Dispersion of nanoclay in Epikote 828 resin is conducted by closed mixing of the liquid composition, mechanical mixing combined with ultrasonic vibration to form masterbatch; meanwhile, nanoclay dispersion in bitumen is processed by melted bitumen mixing. XRD techniques were used to determine the basal d-spacing of nanoclay. The dispersion was performed in Brabender mixer at temperature 40oC, speed 50 rpm, an Epikot/I30E=100/80 masterbatch provided the best dispersion with d001=33.818 Å. After mechanical mixing, an Epikote 828 composition with 4% I30E was sonicated for 5, 10, and 20 minutes. The value d001=41.65 Å achieved after 10 minutes of sonication was deemed optimal. Dispersion of 4% I30E in melted bitumen at 120, 130, 140, 150, and 160oC after 2h reached d001=49.5916 Å for the sample processed at 120oC. At high temperatures, penetration and delamination of bitumen were better than those of Epikote 828 despite the lower molecular weight of Epikote.