Diagnosis and Management of Suspected Pediatric Autoimmune Encephalitis: A Comprehensive, Multidisciplinary Approach and Review of Literature

2021 ◽  
pp. 088307382110646
Author(s):  
Melissa A. Wright ◽  
Cristina C. Trandafir ◽  
Gary R. Nelson ◽  
Aimee O. Hersh ◽  
C. J. Inman ◽  
...  
Keyword(s):  
Iterative Process ◽  
Multidisciplinary Approach ◽  
Pediatric Patients ◽  
Treatment Initiation ◽  
Young Patients ◽  
Autoimmune Encephalitis ◽  
Comprehensive Approach ◽  
Review Of Literature ◽  
Duration Of Treatment ◽  
Diagnosis And Management

Autoimmune encephalitis is an increasingly recognized entity in children. When treated promptly, favorable outcomes are seen in a majority of pediatric patients. However, recognition of autoimmune encephalitis in young patients is challenging. Once autoimmune encephalitis is suspected, additional difficulties exist regarding timing of treatment initiation and duration of treatment, as evidence to guide management of these patients is emerging. Here, we review available literature regarding pediatric autoimmune encephalitis and present our institution's comprehensive approach to the evaluation and management of the disease. These guidelines were developed through an iterative process involving both pediatric neurologists and rheumatologists.

Cyclical Cushing’s Syndrome: A Multidisciplinary Approach to Diagnosis and Management

2019 ◽  
Author(s):  
Ghaith Habboub ◽  
Lee Hwang ◽  
Shahed Tish ◽  
Zahrae Sandouk ◽  
Philip Johnston ◽  
...  
Keyword(s):  
Cushing’S Syndrome ◽  
Multidisciplinary Approach ◽  
Cushing's Syndrome ◽  
Diagnosis And Management

scholarly journals LINC-39. PERFORMANCE STATUS OF PEDIATRIC PATIENTS WITH CENTRAL NERVOUS SYSTEM TUMORS TREATED IN MEXICO, A SINGLE-CENTER EXPERIENCE

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii385-iii386
Author(s):  
Claudia Madrigal-Avila ◽  
Alfonso Perez-Bañuelos ◽  
Rafael Ruvalcaba-Sanchez ◽  
Lourdes Vega-Vega ◽  
Gabriela Escamilla-Asiain
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Multidisciplinary Approach ◽  
Pediatric Patients ◽  
Performance Status ◽  
Retrospective Chart Review ◽  
Cns Tumors ◽  
Surgical Morbidity ◽  
Tertiary Center

Abstract BACKGROUND Central nervous system (CNS) tumors are the most common solid neoplasms in the pediatric age, they comprise about a quarter of all cancers at this age. Little is known about the specific epidemiology of this group in Mexico and there are no reports of results focused on the Performance Status of patients who are treated in a multidisciplinary setting. OBJECTIVE To describe the Performance Status of CNS pediatric patients after being treated with a multidisciplinary approach in a tertiary center. METHODS We report a retrospective chart review of all pediatric patients who presented to the Neuro-Oncology Clinic at Teleton Pediatric Oncology Hospital in Queretaro, Mexico, from December 2014 to January 2020. We analyzed age, gender, the extent of surgical resection and histopathology. Performance Status was assessed using ECOG and Karnofsky/Lansky scores during every patient’s last follow-up visit. RESULTS A total of 56 patients were treated, epidemiology and histopathology variants are similar to those described in the international literature. With a median follow-up of 33 months, 35 patients are alive (62.5%), 28 of them (74.2%) have an excellent Performance Status (ECOG score 0 or Lansky/Karnofsky ≥ 90), 5 (14.2%) scored ECOG 1–2 and only 4 (11.4%) scored ECOG 3–4. CONCLUSIONS A multidisciplinary approach with a focus on Performance Status and the potential for neurological recovery is essential in the management of pediatric patients with CNS tumors. Efforts should be aimed at reducing post-surgical morbidity and early rehabilitation to reintegrate patients into society in the long term.

Catastrophic Antiphospholipid Syndrome Following Lower Extremity Arterial Bypass Surgery: Case Report and Evidence Review

2021 ◽  
pp. 153857442110462
Author(s):  
Ahmed A. Sorour ◽  
Levester Kirksey ◽  
Sarah Keller ◽  
Michael S. O’Connor ◽  
Sean P. Lyden
Keyword(s):  
Case Report ◽  
Lower Extremity ◽  
Antiphospholipid Syndrome ◽  
Current Literature ◽  
Bypass Surgery ◽  
Multidisciplinary Approach ◽  
Catastrophic Antiphospholipid Syndrome ◽  
Diagnosis And Management ◽  
Life Threatening ◽  
Evidence Review

Catastrophic antiphospholipid syndrome (CAPS) is a rare life threatening presentation of antiphospholipid syndrome. Surgery has been proposed as one of the triggering factors for this life threatening entity. There are no detailed published reports in the current literature describing CAPS as a complication after surgery. We report a case of a 21 year old that developed CAPS postoperatively and discuss the multidisciplinary approach for diagnosis and management.

ARTIFICIAL INTELLIGENCE AND ITS STARRING ROLE IN DENTISTRY: A PERSPECTIVE QUESTIONNAIRE STUDY WITH REVIEW OF LITERATURE.

2021 ◽  
pp. 44-47
Author(s):  
V. Shakuntala Soujanya. V ◽  
N.Abhishek Reddy ◽  
K. Kranthi ◽  
Vinuthna Vinuthna ◽  
Prabhakar Rao
Keyword(s):  
Artificial Intelligence ◽  
Oral Cancer ◽  
Multidisciplinary Approach ◽  
Geriatric Patients ◽  
Special Care ◽  
Questionnaire Study ◽  
Review Of Literature ◽  
Advanced Technologies ◽  
Severe Infections ◽  
Dental Diseases

As there is increased preponderance and prevalence of varied diseases affecting huge population including dental diseases like severe infections secondary to pulpal and periodontal pathologies, Maxillary pathologies, Oral cancer, Osteoporosis, esthetical issues like Malocclusion, etc. which in turn should be given special care when it comes to geriatric patients and people suffering with various comorbidities where sometimes it demands for advanced technologies especially in terms of multidisciplinary approach, Articial intelligence has become a boon to dentistry making their work more simpler and accurate. This article is one of its own kind of rare questionnaire study which focus on knowing knowledge, awareness and perception of dentists of northern telangana population regarding Articial intelligence.

scholarly journals Clinical analysis and review of literature on pilomatrixoma in pediatric patients

2020 ◽  
Vol 21 (5) ◽  
pp. 288-293
Author(s):  
Ju Long Hu ◽  
Hyokyung Yoo ◽  
Sung Tack Kwon ◽  
Sukwha Kim ◽  
Jee Hyeok Chung ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Clinical Analysis ◽  
Review Of Literature

scholarly journals Management Of Cardiogenic Shock In Pediatric Patients

2020 ◽  
Vol 9 (2) ◽  
pp. 60
Author(s):  
Dyaris Koentartiwi ◽  
Naura Candini ◽  
Renny Suwarnianty
Keyword(s):  
Cardiogenic Shock ◽  
Cardiac Failure ◽  
Pediatric Patients ◽  
Comprehensive Approach ◽  
Unfavorable Outcome ◽  
Proper Management

Cardiogenic shock is an acute state of end-organ hypoperfusion following cardiac failure. Usually many children have good compensation if they suffered from cardiogenic shock and sometimes delay diagnosis leads to unfavorable outcome. Comprehensive approach in treatment following investigation about the cause of cardiogenic shock is very important and proper management will prevent complication and mortality. 

scholarly journals NURS-10. IMPROVEMENTS IN A BEHAVIORAL TRAINING AND PHARMACOLOGICAL ANXIOLYSIS ALGORITHM FOR INCREASED COMPLIANCE IN PEDIATRIC PATIENTS IN PREPARATION FOR RADIATION THERAPY: A RETROSPECTIVE ANALYSIS

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii422-iii423
Author(s):  
Judy Tran ◽  
Jennifer Holt ◽  
Danielle Crump ◽  
Anita Shea ◽  
Lin Whetzel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pediatric Patients ◽  
Pediatric Population ◽  
Statistical Significance ◽  
Radiation Risk ◽  
Proton Radiation ◽  
Behavioral Training ◽  
Duration Of Treatment ◽  
Behavioral Compliance ◽  
Patients At Risk

Abstract BACKGROUND In the pediatric population, the probability of compliance with radiation involves multifactorial elements. Younger pediatric patients often require anesthesia to ensure accurate delivery of radiotherapy. The purpose of this analysis was to refine our algorithm in pediatric patients to better identify children who would benefit from behavioral training and/or anxiolyxis intervention with the goal of minimizing anesthesia use. METHOD Retrospective data was collected from electronic medical records from 150 pediatric oncology patients <18 years old, treated with photon and proton radiation at our center from August 2016 to December 2019. We identified potential socio-developmental treatment factors thought to impact behavioral compliance and categorized risk factors based on an algorithm to determine risk for noncompliance with radiotherapy. RESULTS Six categories demonstrated statistical significance (p<0.05) in their influence on behavioral compliance during radiotherapy: age category (specifically age <7: Odds ratio [OR] 3.0, 95% Confidence Interval [CI] 1.0, 9.1), need for sedation with prior imaging studies (p<0.001), parental premonition of requiring anesthesia for successful treatment (p<0.001), duration of treatment, primary language (p<0.001), and use of total body irradiation (OR 3.1, 95% CI 1.1, 9.3). CONCLUSION Identification of pre-radiation risk factors allowed for better recognition of patients at risk for treatment non-compliance and for requiring daily sedation. Future studies should focus on implementing the algorithm prospectively in an effort to identify and direct early intervention with behavioral training and/or anxiolytics to minimize the need for sedation.

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