Dolutegravir-induced liver injury leading to sub-acute liver failure requiring transplantation: a case report and review of literature
2017 ◽
Vol 29
(4)
◽
pp. 414-417
◽
Keyword(s):
A patient with human immunodeficiency virus-1 infection presented with sub-acute liver failure, temporally related to commencement of an antiretroviral therapy regimen containing dolutegravir (Triumeq). The patient was not a carrier of HLA-B5701, and abacavir hypersensitivity was unlikely. We believe this is the first report of severe dolutegravir-related hepatotoxicity resulting in sub-acute liver failure and transplantation and highlights a potential need for closer monitoring after drug initiation.
Keyword(s):
2003 ◽
Vol 35
(1)
◽
pp. 62-66
◽
2017 ◽
Vol 21
(2)
◽
pp. 316
◽
2006 ◽
Vol 25
(5)
◽
pp. 427-431
◽
2018 ◽
Vol 67
(8)
◽
pp. 1182-1190
◽