Antilipidemic activity of organic solvent extract from Sorghum bicolor on rats with diet-induced obesity

2010 ◽  
Vol 30 (11) ◽  
pp. 1865-1868 ◽  
Author(s):  
Ill-Min Chung ◽  
Min-A Yeo ◽  
Sun-Jin Kim ◽  
Myong-Jo Kim ◽  
Dong-Sik Park ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Sorghum Bicolor ◽  
High Fat Diet ◽  
Lipid Lowering ◽  
High Fat ◽  
Plasma Total Cholesterol ◽  
Diet Induced Obesity ◽  
Obese Rats ◽  
Pharmacological Potential ◽  
Ethyl Acetate Extracts

The present study evaluated the antiobesity and lipid-lowering effects from dichloromethane and ethyl acetate extracts of Hwanggeumchal Sorghum varieties on Sorghum bicolor. The Hwanggeumchal Sorghum ethyl acetate extracts significantly reduced the plasma total cholesterol and triglyceride levels significantly when given orally at a dose of 50 and 300 mg/kg/day to the high-fat diet-induced obese rats for 2 weeks. These findings demonstrate the excellent pharmacological potential of Hwanggeumchal Sorghum varieties to prevent obesity.

scholarly journals Antiobesity and lipid‐lowering effects of Bifidobacterium spp. in high fat diet‐induced obese rats

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Hyang Mi An ◽  
Min Ji Kim ◽  
Jung Soon Moon ◽  
Joo Yeon Kang ◽  
Do Kyung Lee ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Lipid Lowering ◽  
High Fat ◽  
Obese Rats

Extruded sorghum flour (Sorghum bicolor L.) modulate adiposity and inflammation in high fat diet-induced obese rats

2018 ◽  
Vol 42 ◽  
pp. 346-355 ◽  
Author(s):  
Priscila Marques Arbex ◽  
Maria Eliza de Castro Moreira ◽  
Renata Celi Lopes Toledo ◽  
Leandro de Morais Cardoso ◽  
Helena Maria Pinheiro-Sant'ana ◽  
...  
Keyword(s):  
Sorghum Bicolor ◽  
High Fat Diet ◽  
High Fat ◽  
Sorghum Flour ◽  
Obese Rats ◽  
Sorghum Bicolor L

scholarly journals Extruded sorghum (Sorghum bicolor L.) reduces metabolic risk of hepatic steatosis in obese rats consuming a high fat diet

2018 ◽  
Vol 112 ◽  
pp. 48-55 ◽  
Author(s):  
Andressa Rodrigues de Sousa ◽  
Maria Eliza de Castro Moreira ◽  
Renata Celi Lopes Toledo ◽  
Laércio dos Anjos Benjamin ◽  
Valéria Aparecida Vieira Queiroz ◽  
...  
Keyword(s):  
Sorghum Bicolor ◽  
Hepatic Steatosis ◽  
High Fat Diet ◽  
Metabolic Risk ◽  
High Fat ◽  
Obese Rats ◽  
Sorghum Bicolor L

Effects of diet and obesity on brown adipose metabolism

1984 ◽  
Vol 246 (5) ◽  
pp. E418-E425
Author(s):  
B. E. Levin ◽  
M. B. Finnegan ◽  
E. Marquet ◽  
J. Triscari ◽  
K. Comai ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Metabolic Activation ◽  
Mitochondrial Morphology ◽  
Sprague Dawley ◽  
High Fat ◽  
Interscapular Brown Adipose Tissue ◽  
Diet Induced Obesity ◽  
Brown Adipose ◽  
Obese Rats ◽  
And Control

The effect of diet-induced obesity on interscapular brown adipose tissue (IBAT) was assessed after feeding male Sprague-Dawley rats a high-fat diet for 3-5 mo beginning at 3 mo of age. IBAT pads in 6-mo-old obese rats were heavier (22%), had more lipid (71%), and larger unilocular cells (38%) than chow-fed controls. Mitochondrial morphology, beta-adrenergic receptor binding ([ 125I]iodocyanopindolol), and norepinephrine-stimulated lipolysis were similar in IBAT from obese and control rats. When 8-mo-old chow-fed rats were switched to the high-fat diet for 7-14 days, IBAT pads became hypercellular without cell hypertrophy and with a 70% increase in norepinephrine-induced lipolysis. However, when 8-mo-old obese rats that had been on the high-fat diet for 5 mo were switched to chow for 3 days, IBAT cellularity was unchanged, but norepinephrine-induced lipolysis was increased 70%. Therefore, in lean and obese 6- to 8-mo-old rats, short-term dietary manipulation led to metabolic activation, whereas chronic diet-induced obesity on a stable diet was associated with a return of IBAT metabolism to control levels.

Lipid Lowering and Antioxidant Effect of Miglitol in Triton Treated Hyperlipidemic and High Fat Diet Induced Obese Rats

Lipids ◽  
2013 ◽  
Vol 48 (6) ◽  
pp. 597-607 ◽  
Author(s):  
Atul Shrivastava ◽  
Upma Chaturvedi ◽  
Shiv Vardan Singh ◽  
Jitendra Kumar Saxena ◽  
Gitika Bhatia
Keyword(s):  
High Fat Diet ◽  
Antioxidant Effect ◽  
Lipid Lowering ◽  
High Fat ◽  
Obese Rats

Antiobesity and lipid lowering effects of theaflavins on high-fat diet induced obese rats

2013 ◽  
Vol 5 (3) ◽  
pp. 1142-1150 ◽  
Author(s):  
Duiyan Jin ◽  
Yi Xu ◽  
Xin Mei ◽  
Qing Meng ◽  
Ying Gao ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Lipid Lowering ◽  
High Fat ◽  
Obese Rats

scholarly journals High-fat diet-induced metabolic syndrome and oxidative stress in obese rats are ameliorated by yogurt supplementation

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Shoumen Lasker ◽  
Md Mizanur Rahman ◽  
Faisal Parvez ◽  
Mushfera Zamila ◽  
Pintu Miah ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Metabolic Syndrome ◽  
High Fat Diet ◽  
Alternative Therapy ◽  
High Fat ◽  
Stress Markers ◽  
Diet Induced Obesity ◽  
Obese Rats ◽  
Male Wistar Rats ◽  
And Oxidative Stress

AbstractThe main objective of this experiment was to determine the effects of yogurt supplementation on fat deposition, oxidative stress, inflammation and fibrosis in the liver of rats with high-fat (HF) diet-induced obesity. Male Wistar rats were used in this study and were separated into the following four different groups: the control, control + yogurt, high fat and high fat+ yogurt groups. The high fat groups received a HF diet for eight weeks. A 5% yogurt (w/w) supplement was also provided to rats fed the HF diet. Yogurt supplementation prevented glucose intolerance and normalized liver-specific enzyme activities in the HF diet-fed rats. Yogurt supplementation also significantly reduced the levels of oxidative stress markers in the plasma and liver of HF diet-fed rats. Moreover, inflammatory cell infiltration, collagen deposition and fibrosis in the liver of HF diet-fed rats were also prevented by yogurt supplementation. Furthermore, yogurt supplementation normalized the intestinal lining and brush border in HF diet-fed rats. This study suggests that yogurt supplementation potentially represents an alternative therapy for the prevention of metabolic syndrome in HF diet-fed rats.

Extruded sorghum (Sorghum bicolor L.) improves gut microbiota, reduces inflammation, and oxidative stress in obese rats fed a high-fat diet

2019 ◽  
Vol 58 ◽  
pp. 282-291 ◽  
Author(s):  
Andressa Rodrigues de Sousa ◽  
Maria Eliza de Castro Moreira ◽  
Mariana Grancieri ◽  
Renata Celi Lopes Toledo ◽  
Fernanda de Oliveira Araújo ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gut Microbiota ◽  
Sorghum Bicolor ◽  
High Fat Diet ◽  
High Fat ◽  
Obese Rats ◽  
And Oxidative Stress ◽  
Sorghum Bicolor L
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