Protective effect of curcumin, silymarin and N-acetylcysteine on antitubercular drug-induced hepatotoxicity assessed in an in vitro model

2012 ◽  
Vol 31 (8) ◽  
pp. 788-797 ◽  
Author(s):  
M Singh ◽  
P Sasi ◽  
V H Gupta ◽  
G Rai ◽  
D N Amarapurkar ◽  
...  
Keyword(s):  
Protective Effect ◽  
In Vitro Model ◽  
Antitubercular Drug ◽  
Drug Induced ◽  
Vitro Model

Synergism between fluoxetine and the mGlu2/3 receptor agonist, LY379268, in an in vitro model for antidepressant drug-induced neurogenesis

2008 ◽  
Vol 54 (2) ◽  
pp. 428-437 ◽  
Author(s):  
F. Matrisciano ◽  
M. Zusso ◽  
I. Panaccione ◽  
B. Turriziani ◽  
A. Caruso ◽  
...  
Keyword(s):  
Receptor Agonist ◽  
In Vitro Model ◽  
Antidepressant Drug ◽  
Drug Induced ◽  
Vitro Model

scholarly journals Porcine hepatocytes culture on biofunctionalized 3D inverted colloidal crystal scaffolds as an in vitro model for predicting drug hepatotoxicity

RSC Advances ◽  
2019 ◽  
Vol 9 (31) ◽  
pp. 17995-18007 ◽  
Author(s):  
Lingyan Wu ◽  
Gaia Ferracci ◽  
Yan Wang ◽  
Teng Fei Fan ◽  
Nam-Joon Cho ◽  
...  
Keyword(s):  
In Vitro Model ◽  
Colloidal Crystal ◽  
Three Dimensional ◽  
Drug Induced ◽  
Attrition Rates ◽  
Common Causes ◽  
Vitro Model ◽  
Colloidal Crystal Scaffolds

As drug-induced hepatotoxicity represents one of the most common causes of drug failure, three-dimensional in vitro liver platforms represent a fantastic toolbox to predict drug toxicity and reduce in vivo studies and drug attrition rates.

Novel in vitro model captures drug-induced inflammation as a mechanism contributing to hepatotoxicity

2021 ◽  
Vol 350 ◽  
pp. S59
Author(s):  
F. Tasnim ◽  
X. Huang ◽  
Y.T. Soong ◽  
H. Yu
Keyword(s):  
In Vitro Model ◽  
Drug Induced ◽  
Vitro Model
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