Spindle Cell Lipoma of the Foot: A Case Report and Literature Review

1995 ◽  
Vol 16 (4) ◽  
pp. 220-226 ◽  
Author(s):  
Kevin R. Math ◽  
Helene Pavlov ◽  
Edward DiCarlo ◽  
Walther H. O. Bohne
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Spindle Cell ◽  
Soft Tissue Tumors ◽  
Imaging Features ◽  
Spindle Cell Lipoma ◽  
Imaging Evaluation ◽  
Presumptive Diagnosis ◽  
Pleomorphic Lipoma ◽  
Atypical Lipoma

Lipomas are among the most commonly encountered soft tissue tumors in clinical practice, though they are rare in the foot. Although a presumptive diagnosis is typically made clinically, those tumors with atypical clinical features may require radiological consultation. Difficulty arises when radiographic features are not typical of lipoma. We present a fatty soft tissue tumor of the foot with nonadipose elements on magnetic resonance imaging evaluation. Differentiation of lipoma variants (e.g., spindle cell lipoma, atypical lipoma, pleomorphic lipoma, lipoblastoma, angiolipoma) from liposarcoma based on imaging features is not possible, necessitating surgical resection for definitive histological diagnosis.

scholarly journals Nodular Mucinosis of the Breast in a Male: Reassessment of Diagnostic Criteria and Proposal for Its Classification as a Soft Tissue Tumor in the Myofibroblastoma and Spindle Cell Lipoma Spectrum

2014 ◽  
Vol 1 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Maria Teresa Fernández-Figueras ◽  
Dmitry V. Kazakov ◽  
Raquel López Martos ◽  
Isabel Ojanguren ◽  
Jordi Vila ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Diagnostic Criteria ◽  
Soft Tissue Tumor ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Tissue Tumor

scholarly journals Lipomas of Larynx: The Rare Entities

2012 ◽  
Vol 2 (2) ◽  
pp. 79-81 ◽  
Author(s):  
Somanath B Megalamani ◽  
Ravindra Gadag ◽  
A Raza ◽  
A Satish
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Spindle Cell ◽  
Anterior Commissure ◽  
The Body ◽  
Spindle Cell Lipoma ◽  
Tissue Tumor

ABSTRACT Lipoma is the commonest soft tissue tumor arising anywhere in the body, but its occurrence in the larynx is relatively rare. We present a rarest case of lipoma with cartilaginous metaplasia arising from the larynx just above the anterior commissure. The second case report is about a large spindle cell lipoma of larynx presented with stridor. How to cite this article Megalamani SB, Gadag R, Raza A, Satish A. Lipomas of Larynx: The Rare Entities. Int J Phonosurg Laryngol 2012;2(2):79-81.

scholarly journals The Rapidly Expanding Group of RB1-Deleted Soft Tissue Tumors: An Updated Review

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 430
Author(s):  
Sasha Libbrecht ◽  
Jo Van Dorpe ◽  
David Creytens
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Adult Population ◽  
Suppressor Gene ◽  
Soft Tissue Tumors ◽  
Mesenchymal Tumors ◽  
Pleomorphic Liposarcoma ◽  
Molecular Features ◽  
Pleomorphic Lipoma ◽  
Older Adult Population

The classification of soft tissue tumors has evolved considerably in the last decade, largely due to advances in understanding the pathogenetic basis of many of these, sometimes rare, tumors. Deletion of Retinoblastoma 1 (RB1), a well-known tumor suppressor gene, has been implicated in the tumorigenesis of a particular group of soft tissue neoplasms. This group of so-called ”RB1-deleted soft tissue tumors” has been rapidly expanding in recent years, currently consisting of spindle cell/pleomorphic lipoma, atypical spindle cell/pleomorphic lipomatous tumor, pleomorphic liposarcoma, myofibroblastoma, cellular angiofibroma, and acral fibromyxoma. Most of these neoplasms, except pleomorphic liposarcoma, are considered benign entities and are mainly described in the older adult population. This article will review the currently known morphological, immunohistochemical, and molecular features of this heterogeneous group of mesenchymal tumors with an emphasis on differential diagnosis.

scholarly journals Dendritic Myxofibrolipoma: Often Misdiagnosed as Sarcoma

2011 ◽  
Vol 4 (3) ◽  
pp. 171-174 ◽  
Author(s):  
Awatif Y. Al-Maskery ◽  
Salem M. Al-Sidairy ◽  
Aisha S. Al-Hamadani
Keyword(s):  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Complete Excision ◽  
Lower Lip ◽  
Benign Soft Tissue Tumor ◽  
Proper Diagnosis ◽  
Fibrous Tumor ◽  
Combined Feature

The author describes a benign soft tissue tumor that could be easily mistaken for sarcoma. It represents a combined feature of solitary fibrous tumor and spindle cell lipoma. The clinical presentation, diagnosis, and management of this lesion are discussed. It highlights the importance of proper diagnosis to prevent unnecessary and ineffective treatment by clinicians as the complete excision of this lesion is the treatment of choice and recurrence is very unlikely. It is believed that this case is the first reported case of dendritic myxofibrolipoma occurring in the lower lip mucosa in an Omani patient.

scholarly journals Lipoma of the Thumb: Spindle Cell Subtype

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Johnny El Rayes ◽  
Roula Bou Sader ◽  
Elie Saliba
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Clinical Examination ◽  
Spindle Cell ◽  
Excisional Biopsy ◽  
Spindle Cell Lipoma ◽  
Cell Subtype ◽  
Soft Tissue Swelling ◽  
Palmar Aspect

We report hereby the case of a 61-year-old man who presented with a soft-tissue swelling on the palmar aspect of the thumb. A detailed clinical examination followed by ultrasonography and excisional biopsy confirmed a spindle cell lipoma. Lipomas are rare in the hand and exceptional in the fingers, and we report, to our knowledge, the first spindle cell lipoma in the thumb to help in the differential diagnosis of a similar swelling.

scholarly journals Ultrasound Ablation: New Possibilities for Treatment of Bone and Soft-Tissue Tumors

2010 ◽  
Vol 17 (2) ◽  
pp. 41-49
Author(s):  
G I Nazarenko ◽  
V Sh Chen ◽  
A N Khitrova
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Secondary Infection ◽  
Local Treatment ◽  
Soft Tissue Tumors ◽  
Treatment Technique ◽  
Tumor Type ◽  
Coagulative Necrosis ◽  
Ultrasound Ablation ◽  
Physical Principles

Focused high intensity ultrasound (HIFU) with sighting influence on tumor enabled to cause its complete coagulative necrosis without damage to intact environmental tissues. The possibilities of ultrasound ablation as the method of local treatment of bone and soft-tissue tumor were considered. Physical principles of method, criteria for patient selection, treatment technique as well as clinical outcomes and their evaluation were presented. Advantages of method are non-invasiveness, less traumatization, less technical complexity and dependence on surgeon skill compared with other sparing operations and methods of ablation. When necessary HIFU may be repeated several times. Effect of HIFU is independent on tumor type. Possible complications (secondary infection in coagulative necrosis zone, peripheral nerves damage, pathological fractures) and measures of their prevention are presented.

Adipocyte-rich CTNNB1-mutated Intramuscular Gardner Fibroma Progressing to Desmoid Fibromatosis

2020 ◽  
pp. 109352662096880
Author(s):  
Andrea Bakker ◽  
Jonathan C Slack ◽  
Mara Caragea ◽  
Kyle C Kurek ◽  
Marie-Anne Bründler
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Soft Tissue Tumors ◽  
Molecular Testing ◽  
Tissue Mass ◽  
Desmoid Fibromatosis ◽  
Benign Soft Tissue Tumor ◽  
First Time ◽  
Generation Sequencing

Gardner fibroma (GF) is a benign soft-tissue tumor that is associated with Gardner syndrome and can progress to, or co-occur with, desmoid fibromatosis (DF). Herein, we report a unique case of an 11-year-old boy who presented with a rapidly growing soft-tissue mass after biopsy of a stable fat-rich lesion present in the calf muscles since infancy, with Magnetic resonance imaging findings suggesting an intramuscular adipocytic tumor. The resection showed GF and DF. DF arising from a preexisting GF (the so-called “GF-DF sequence”) is a well-documented phenomenon. Although immunohistochemistry was negative for nuclear β-catenin expression, a CTTNB1 S45F mutation, which has been associated with aggressive behavior in DF, was identified in both components using a next-generation sequencing-based molecular assay. This is the first time a mutation in CTNNB1 has been identified in GF and the GF–DF sequence, thus expanding our knowledge of the molecular pathogenesis of the GF–DF sequence and highlighting the role of molecular testing in pediatric soft-tissue tumors. The histologic findings of an adipocyte-rich intramuscular GF also are unique, expanding the morphological spectrum of GF and adding GF to the differential diagnosis of intramuscular lesions with an adipocytic component.

Soft-Tissue Tumors of the Hand—Imaging Features

2020 ◽  
Vol 71 (2) ◽  
pp. 161-173 ◽  
Author(s):  
Gregory Scott Stacy ◽  
Jeffrey Bonham ◽  
Anthony Chang ◽  
Stephen Thomas
Keyword(s):  
Soft Tissue ◽  
Daily Practice ◽  
Soft Tissue Tumors ◽  
Vascular Lesions ◽  
Imaging Features ◽  
Imaging Studies ◽  
Adipocytic Tumors ◽  
Imaging Characteristics ◽  
Tumors Of The Hand ◽  
Structured Approach

Imaging studies of the hands and fingers are common, and radiologists are generally comfortable with traumatic and degenerative conditions which arise frequently in daily practice. However, a variety of common and uncommon soft-tissue tumors also occur in the hand, the appropriate diagnosis of which can be a source of confusion for both clinicians and radiologists. These lesions often have overlapping imaging characteristics; however, a structured approach can help provide a focused differential diagnosis and impact further workup and management. We discuss several such tumors, categorizing them as cystic-appearing, noncystic masses along tendons and aponeuroses, adipocytic tumors, vascular lesions, and miscellaneous lesions with imaging features that can aid diagnosis.

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