Comments on one- versus two-stage procedure for transposed brachio-basilic arteriovenous fistulae

2021 ◽  
pp. 112972982199725
Author(s):  
Joon Ho Hong

The maturation and long-term patency of transposed brachio-basilic arteriovenous fistulae can best be achieved not by adopting a two-stage construction procedure, but by using a loop configuration and an anastomosis angle that allows for the most favorable flow dynamics.

2021 ◽  
pp. 000313482110111
Author(s):  
Joon H. Hong

The transposed brachiobasilic arteriovenous fistula is often constructed by employing a two-stage procedure for better maturation and long-term patency, but its validity on overall outcomes remains controversial. A single-center’s experience is presented herein, comparing one- and two-stage approaches on 229 consecutive first-time arteriovenous access constructed in the upper arm with a loop configuration and an obtuse anastomosis angle that provide favorable flow dynamics. The one- and two-year patency rates were equivalent between the two approaches, but the fistula rate was greater and the maturation time was shorter with the one-stage procedure.


BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e044219
Author(s):  
J X Harmeling ◽  
Kevin Peter Cinca ◽  
Eleni-Rosalina Andrinopoulou ◽  
Eveline M L Corten ◽  
M A Mureau

IntroductionTwo-stage implant-based breast reconstruction is the most commonly performed postmastectomy reconstructive technique. During the first stage, a tissue expander creates a sufficiently large pocket for the definite breast implant placed in the second stage. Capsular contracture is a common long-term complication associated with implant-based breast reconstruction, causing functional complaints and often requiring reoperation. The exact aetiology is still unknown, but a relationship between the outer surface of the implant and the probability of developing capsular contracture has been suggested. The purpose of this study is to determine whether polyurethane-covered implants result in a different capsular contracture rate than textured implants.Methods and analysisThe Textured Implants versus Polyurethane-covered Implants (TIPI) trial is a multicentre randomised controlled trial with a 1:1 allocation rate and a follow-up of 10 years. A total of 321 breasts of female adults undergoing a two-stage breast reconstruction will be enrolled. The primary outcome is capsular contracture at 10-year follow-up which is graded with the modified Baker classification. It is analysed with survival analysis using a frailty model for clustered interval-censored data, with both an intention-to-treat and per-protocol approach. Secondary outcomes are other complication rates, surgical revision rate, patient satisfaction and quality of life and user-friendliness. Outcomes are measured 2 weeks, 6 months, 1, 2, 3, 5 and 10 years postoperatively. Interim analysis is performed when 1-year, 3-year and 5-year follow-up is completed.Ethics and disseminationThe trial has been reviewed and approved by the Medical Research Ethics Committee of the Erasmus MC, University Medical Centre Rotterdam (MEC-2018-126) and locally by each participating centre. Written informed consent will be obtained from each study participant. The results will be disseminated by publication in peer-reviewed journals.Trial registrationNTR7265.


1987 ◽  
Vol 29 (5) ◽  
pp. 473-473
Author(s):  
M. Fermand ◽  
D. Reizine ◽  
J. P. Melki ◽  
M. C. Riche ◽  
J. J. Merland

2015 ◽  
Vol 47 (13) ◽  
pp. 1174-1179 ◽  
Author(s):  
Angela Sobiesierski ◽  
Robert Thomas ◽  
Philip Buckle ◽  
David Barrow ◽  
Peter M. Smowton

2019 ◽  
Vol 19 (1) ◽  
pp. 141-157 ◽  
Author(s):  
Paula Guimaraes ◽  
Ricardo P.C. Leal ◽  
Peter Wanke ◽  
Matthew Morey

Purpose This paper aims to investigate the long-term impact of shareholder activism on Brazilian listed companies. Design/methodology/approach This study uses a sample of 194 companies in 2010, 2012 and 2014 and a two-stage data envelopment analysis to generate an efficiency score based on corporate governance, ownership structure and financial characteristics of companies. In the second stage, the study applies a bootstrap truncated regression to identify whether there is a relationship between the efficiency scores and a company-level activism index. Findings The results show a negative correlation between the efficiency scores and the activism index, suggesting that activist shareholders tend to target less efficient companies. A time analysis over the period 2010-2014 does not offer evidence of impacts of activism on changes of the efficiency scores. Practical implications Activist shareholders target less efficient companies. Shareholder activism increased after regulation that facilitated shareholder voting and required greater company transparency was introduced. Originality/value The two-stage nature of the procedure used in the analysis ascertains that this result is not spurious, assuring data separability between productive resources and contextual variables. This study contributes to the scarce literature on activism in emerging markets.


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