scholarly journals Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia

2018 ◽  
Vol 11 ◽  
pp. 117955221877862 ◽  
Author(s):  
Hassan Brim ◽  
Anahita Shahnazi ◽  
Mehdi Nouraie ◽  
Dilhana Badurdeen ◽  
Adeyinka O Laiyemo ◽  
...  

Background: Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients. Aim: To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men. Methods: We reviewed medical records (n = 422) of patients referred for evaluation of IDA from 2008 to 2012. Iron deficiency anemia was diagnosed using clinical laboratory tests. The results of esophagogastroduodenoscopy, colonoscopy, and pathology specimens along with demographic data were abstracted and analyzed using Stata. Results: The mean age was 61.9 years, and 50.5% were women. In total, 189 patients (45%) had gross gastrointestinal (GI) bleeding. The most frequent diagnoses were gastritis (40%), benign colonic lesions (13%), esophagitis (9%), gastric ulcer (6%), and duodenitis (6%). GI bleeding was significantly more frequent in men ( P = 0.001). Benign and malignant colonic lesions were significantly more present among older patients: 16% vs 6% ( P = .005) and 5% vs 0% ( P = .008), respectively. Colitis was more prevalent in younger patients (⩽50): 11% vs 2% ( P = .001). In patients with gross lower GI bleeding, the top diagnoses were gastritis (25%), benign colon tumors (10%), and duodenitis (6%). Colon cancer was diagnosed among 15 patients, and all these patients were older than 50 years of age. Conclusions: Gastritis and colonic lesions are most common associated lesions with IDA among African Americans. So bidirectional endoscopy is required for unrevealing of the cause of IDA in asymptomatic patients.

2015 ◽  
Vol 148 (4) ◽  
pp. S-596
Author(s):  
Anahita Shahnazi ◽  
Hassan Brim ◽  
Tahmineh Haidary ◽  
Mya T. Myint ◽  
Shiva Salehian ◽  
...  

2020 ◽  
Vol 21 (11) ◽  
pp. 3821
Author(s):  
Antonino Davide Romano ◽  
Annalisa Paglia ◽  
Francesco Bellanti ◽  
Rosanna Villani ◽  
Moris Sangineto ◽  
...  

Iron deficiency (ID) is the most frequent nutritional deficiency in the whole population worldwide, and the second most common cause of anemia in the elderly. The prevalence of anemia is expecting to rise shortly, because of an ageing population. Even though WHO criteria define anemia as a hemoglobin serum concentration <12 g/dL in women and <13 g/dL in men, several authors propose different and specific cut-off values for the elderly. Anemia in aged subjects impacts health and quality of life, and it is associated with several negative outcomes, such as longer time of hospitalization and a higher risk of disability. Furthermore, it is an independent risk factor of increased morbidity and mortality. Even though iron deficiency anemia is a common disorder in older adults, it should be not considered as a normal ageing consequence, but a sign of underlying dysfunction. Relating to the molecular mechanism in Iron Deficiency Anemia (IDA), hepcidin has a key role in iron homeostasis. It downregulates the iron exporter ferroportin, inhibiting both iron absorption and release. IDA is frequently dependent on blood loss, especially caused by gastrointestinal lesions. Thus, a diagnostic algorithm for IDA should include invasive investigation such as endoscopic procedures. The treatment choice is influenced by the severity of anemia, underlying conditions, comorbidities, and the clinical state of the patient. Correction of anemia and iron supplementation should be associated with the treatment of the causal disease.


2005 ◽  
Vol 135 (11) ◽  
pp. 2572-2577 ◽  
Author(s):  
Lora L. Iannotti ◽  
Kimberly O. O'Brien ◽  
Shih-Chen Chang ◽  
Jeri Mancini ◽  
Maureen Schulman-Nathanson ◽  
...  

2021 ◽  
Vol 29 (01) ◽  
pp. 121-125
Author(s):  
Samina Batool ◽  
Nadia Qamar ◽  
Akasha Islam ◽  
Saman Jamal ◽  
Qurat-ul-Ain Rana

Objective: To determine frequency of iron deficiency anemia among the children having febrile seizures. Study Design: Descriptive Cross Sectional study. Setting: Pediatric Unit Allama Iqbal Memorial Teaching Hospital Sialkot. Period: September 2020 to February 2021. Material & Methods: Total 70 children were studied with age six months to 10 years with either gender presenting with febrile seizures. All data of the patients was documented including demographic data like age, gender, residential area, educational status, socioeconomic status and clinical findings at the time of presentation like fever, fits and duration of symptoms etc. Blood hemoglobin and ferritin level were tested of each patient to evaluate iron deficiency anemia. Results: There were 65.7% male and 34.3% female cases in this study. Age range of the patients was 6 months to 10 years with mean age of 4.36 ± 2.71 years. Most of the children (60%) were below three years of age. Mostly children belonged to low and middle socioeconomic status with the frequency of 42.8% and 45.7% respectively. Iron deficiency anemia was found in 38.6% cases. Majority of the mothers were illiterate (65%). There were 44.3% cases from rural areas and 55.7% from urban area. Conclusion:  Iron deficiency anemia is a common problem among children with febrile seizures, younger than 03 years and belonging to rural areas. Illiterate mothers, is an important risk factor of iron deficiency anemia in their children.


2020 ◽  
Vol 10 (2) ◽  
pp. 68-73
Author(s):  
Omid Sabet Ghadam ◽  
Mohammad Fararouei ◽  
Mansour Shahraki   ◽  
Zahra Sohrabi

Background and Objective: Iron deficiency anemia (IDA) is the most common type of micronutrient deficiency in the world. Numerous reports indicated that adolescence is a period which has an increased risk of development of IDA. Given the importance of IDA and lack of studies in Saravan, a city of Iran, this study was performed to assess the prevalence of IDA among adolescent girls.Methods: In this cross-sectional study, 460 high-school girls were randomly selected. Demographic data was collected using a questionnaire. Knowledge, attitude and practice of participants with regard to iron deficiency anemia was measured at the beginning of the interview. Accordingly, five cc of blood sample was drawn from each student to determine the prevalence of anemia, which was defined by a hemoglobin level lower than 12 mg / dL. The level of ferritin was analyzed to confirm the IDA for students diagnosed with anemia. Ferritin level lower than 12 ?g / dl was considered as IDA. Data was analyzed using SPSS software version 22.Results: Prevalence of anemia and IDA was 24% (n = 111) and 12.6% (n = 58), respectively. Results showed that 37 % of students had good knowledge, 45. 5 % good attitude, and 6.7 % had good practice. Also, there was no significant association between IDA and socio-economic status including parental education, job, and household income (P>0.05).Conclusion: The findings of this study showed that the prevalence of IDA was moderate in Saravan city. Given the importance of IDA and its complications, further studies are needed, especially in high risk populations for IDA such as children.


2021 ◽  
Vol 116 (1) ◽  
pp. S975-S976
Author(s):  
Jamil M. Shah ◽  
Eric O. Then ◽  
Manan A. Jhaveri ◽  
Mohamed Barakat ◽  
Yingxian Liu ◽  
...  

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