The use of multiple population-based data sources for estimating MS sex ratio trends over time

Abstract Background There is limited to no evidence of the prevalence and incidence rates of inflammatory bowel disease (IBD) among Indigenous peoples. In partnership with Indigenous patients and family advocates, we aimed to estimate the prevalence, incidence, and trends over time of IBD among First Nations (FNs) since 1999 in the Western Canadian province of Saskatchewan. Methods We conducted a retrospective population-based study linking provincial administrative health data from the 1999-2000 to 2016-2017 fiscal years. An IBD case definition requiring multiple health care contacts was used. The prevalence and incidence data were modeled using generalized linear models and a negative binomial distribution. Models considered the effect of age groups, sex, diagnosis type (ulcerative colitis [UC], Crohn disease [CD]), and fiscal years to estimate prevalence and incidence rates and trends over time. Results The prevalence of IBD among FNs increased from 64/100,000 (95% confidence interval [CI], 62-66) in 1999-2000 to 142/100,000 (95% CI, 140-144) people in 2016-2017, with an annual average increase of 4.2% (95% CI, 3.2%-5.2%). Similarly, the prevalence of UC and CD, respectively, increased by 3.4% (95% CI, 2.3%-4.6%) and 4.1% (95% CI, 3.3%-4.9%) per year. In contrast, the incidence rates of IBD, UC, and CD among FNs depicted stable trends over time; no statistically significant changes were observed in the annual change trend tests. The ratio of UC to CD was 1.71. Conclusions We provided population-based evidence of the increasing prevalence and stable incidence rates of IBD among FNs. Further studies are needed in other regions to continue understanding the patterns of IBD among Indigenous peoples.

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EP644 Trends over time in use of primary and adjuvant hormonal therapy for endometrial cancer: a population based study

10.1136/ijgc-2019-esgo.700 ◽

2019 ◽

Author(s):

WJ van Weelden ◽

R Bretveld ◽

S van Erp ◽

S Engels ◽

A Romano ◽

...

Keyword(s):

Endometrial Cancer ◽

Hormonal Therapy ◽

Population Based ◽

Adjuvant Hormonal Therapy ◽

Population Based Study ◽

Trends Over Time ◽

Over Time

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Geographical Variations in Sex Ratio Trends over Time in Multiple Sclerosis

PLoS ONE ◽

10.1371/journal.pone.0048078 ◽

2012 ◽

Vol 7 (10) ◽

pp. e48078 ◽

Cited By ~ 108

Author(s):

Maria Trojano ◽

Guglielmo Lucchese ◽

Giusi Graziano ◽

Bruce V. Taylor ◽

Steve Simpson ◽

...

Keyword(s):

Multiple Sclerosis ◽

Sex Ratio ◽

Geographical Variations ◽

Trends Over Time ◽

Over Time

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Mo1917 - 5-Asa Prescription Trends over Time in Inflammatory Bowel Disease 1996-2015 - A UK Population-Based Study

Gastroenterology ◽

10.1016/s0016-5085(18)32881-6 ◽

2018 ◽

Vol 154 (6) ◽

pp. S-851

Author(s):

Vipul Jairath ◽

Suvi Hokkanen ◽

Leonard Guizzetti ◽

Naomi Boxall ◽

Sarah Campbell-Hill ◽

...

Keyword(s):

Inflammatory Bowel Disease ◽

Bowel Disease ◽

Population Based ◽

Population Based Study ◽

Trends Over Time ◽

Inflammatory Bowel ◽

Over Time

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Data Linkage Methods in Manitoba

International Journal for Population Data Science ◽

10.23889/ijpds.v3i4.942 ◽

2018 ◽

Vol 3 (4) ◽

Author(s):

Ken Turner ◽

Randy Walld ◽

Shelley Derksen

Keyword(s):

Data Linkage ◽

Population Based ◽

Data Sources ◽

Data Repository ◽

Linkage Methods ◽

The Individual ◽

Privacy And Confidentiality ◽

Manual Review ◽

Over Time ◽

Outcome Metrics

IntroductionAt the Manitoba Centre for Health Policy (MCHP), we have been performing data linkage for over 25 years. Over time, the Manitoba Population Research Data Repository (MPRDR) has expanded to over 80 datasets. Data linkage methods are key to bringing all this data together for population-based research. Objectives and ApproachThe presentation will include a detailed description of the individual steps involved in the data linkage process and provide information about the methods developed and knowledge gained over time at MCHP. We will present different scenarios linking health, education, social and justice data and the choices that are made prior to and during data linkage. The data linkage process and linkage methods, including data validation techniques, will be illustrated with examples from our work. ResultsThe presentation will describe the different types of data we have in the MPRDR and illustrate how the data are processed in a de-identified manner so that privacy and confidentiality are maintained. The presentation will provide details on the data linkage methods used, dependent on the type of data sources being linked. This involves identifying and describing a 5-step data linkage process, including: pre-processing (gaining knowledge about the data and cleaning/standardization techniques); searching for and selecting the appropriate linkage variables; applying different linkage techniques (e.g.: deterministic, probabilistic, “fuzzy matching” and manual review) to the data, “rules” for deciding when data linkage should occur, and reporting and Interpreting linkage outcome metrics and quality. Conclusion/ImplicationsOur ability to link different data sources provides the capacity to study questions and complex issues related to health, social, education and justice from a population perspective. The techniques and methods described in this presentation should be applicable to other organizations linking administrative data.

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What do we know about financial protection in health in Africa? A systematic review

10.21203/rs.3.rs-19482/v1 ◽

2020 ◽

Author(s):

Grace Achungura Kabaniha ◽

Doris Osei Afriyie ◽

Mayur L Mandalia ◽

John E Ataguba

Keyword(s):

Systematic Review ◽

Health Spending ◽

Health Expenditures ◽

Data Sources ◽

Financial Protection ◽

African Region ◽

Equity Analysis ◽

Wide Range ◽

Trends Over Time ◽

Over Time

Abstract Background Financial protection is one of the main indicators to assess progress towards Universal Health Coverage. Efforts have been made globally to monitor financial protection. However, progress in the African Region is limited. Methods A systematic review was conducted to assess financial protection in health in Africa. The search of five databases was conducted between March and May 2019. Studies were included if they conducted empirical analyses on one or two dimensions of financial protection—catastrophic and impoverishing health expenditures, at the national or subnational levels. The review included peer-review articles, grey literature and reports. Data extraction included study characteristics, the dimension of financial protection, including methods and data sources, and the type of analysis (incidence, equity analysis, determinants, trends over time) of financial protection. Results Fifty-one studies met the inclusion criteria of the review with at least one study in 41 out of the 47 countries in the WHO African Region. The analyses of the included studies showed that catastrophic and impoverishing health spending occurs in all the countries in the region, albeit at different levels. Various national household surveys were used as data sources. Also, the studies used different methods to assess financial protection. The incidence ranged from 0.29% in Zambia in 2010 to 16.4% in Nigeria in 2009 at a 10% threshold. Due to the wide range of data sources and methods, comparison of findings within and across countries was difficult. Furthermore, the majority of the studies focused on in-depth analysis of catastrophic health spending than impoverishing. Trends over time of both catastrophic and impoverishing health expenditures were even limited in single-country analysis. Conclusion This review provides evidence that generally, financial protection is being monitored at the national level in the African Region, and the incidence of financial protection has increased generally in the Region. Further research on financial protection should explore methods to harmonize the estimation of OOP from different surveys In addition, analyses should go beyond measuring the incidence of financial protection and also focus on equity analysis, looking at the drivers and trends of both dimensions of financial protection.

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1325Longitudinal epidemiology of MS in the Greater Hobart region, 1961 to 2019

International Journal of Epidemiology ◽

10.1093/ije/dyab168.605 ◽

2021 ◽

Vol 50 (Supplement_1) ◽

Author(s):

Steve Simpson-Yap ◽

Roberts Atvar ◽

Bruce Taylor

Keyword(s):

Mortality Rate ◽

Sex Ratio ◽

Poisson Regression ◽

Latitudinal Gradient ◽

Mortality Rates ◽

Data Sources ◽

Lower Latitude ◽

Incidence And Mortality ◽

Crude Prevalence ◽

Over Time

Abstract Background The Greater Hobart region (42.3°S) of Tasmania has the highest frequencies of MS in Australia, this consistent across studies conducted over the last half century. However, the degree of excess compared to mainland sites like Newcastle (32.5°S) has declined over time. Methods Cases were recruited from clinic-based samples and other multiple other data sources. Prevalence date was 1 June 2019. 2019 prevalence and 2009-19 incidence and mortality rates were estimated. Prevalence and incidence and mortality rates were age/sex-standardised to the 1961 and 1954 Hobart populations, respectively, to allow longitudinal comparisons. Female:male prevalence and incidence sex-ratios were also assessed. Differences between timepoints were assessed using Poisson regression. Results 472 MS cases (female:71.4%) resident on prevalence day were identified, a crude prevalence=212.3/100,000 (155.8 age/sex-standardised), 57% increase vs 2009 and 388.0% vs 1961. The 2009-19 incidence rate=7.56/100,000 person-years (7.03 age/sex-standardised), 91% increase vs 2001-9 and 218.1% vs 1951-61. The 2009-19 mortality rate was 2.25/100,000 person-years (1.12 age/sex-standardised), comparable to 2001-9 (1.00). The age/sex-standardised prevalence-sex-ratio was 2.61, comparable to 2009 (2.65), but the incidence-sex-ratio was 2.68, 31% increase vs 2001-9 (2.05). Conclusions Prevalence and incidence continue to be high in Hobart, although the differences compared to lower-latitude Newcastle have attenuated significantly. Changes in lifestyle may underlie the deterioration of the latitudinal gradient of MS in Australia. Further investigation is required to define the factors that drive these associations. Key messages MS prevalence and incidence are still highest in Australia in southern Tasmania but the latitudinal variation is declining.

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Challenges and Way Forward for Establishing Population Based Cancer Registry in Nepal

Journal of Nepal Health Research Council ◽

10.33314/jnhrc.v18i3.2703 ◽

2020 ◽

Vol 18 (3) ◽

pp. 544-546

Author(s):

Ranjeeta Subedi ◽

Meghnath Dhimal ◽

Atul Budukh ◽

Pradeep Gyawali ◽

Anjani Kumar Jha

Keyword(s):

Information System ◽

Cancer Registry ◽

Health Management ◽

Cancer Control ◽

Population Based ◽

Mortality Pattern ◽

Trends Over Time ◽

Adequate Coverage ◽

Sustainable Population ◽

Over Time

Population Based Cancer Registry plays a crucial role in cancer control through identifying cancer incidence, mortality, pattern and trends over time in a particular population. The registry is in a very infancy stage in Nepal. During the process of establishing Population Based Cancer Registry in Nepal, the major challenges include adequate coverage of the cases, high cost of registration, sustainability along with expansion of the registry to other regions and non-linkage of Hospital Based Cancer Registry with Population Based Cancer Registry. However, the approach of mobilization of field enumerators at the end of year once had increased coverage of the cases. Similarly, the linkage of Population Based Cancer Registry with the existing Health Management and Information System will help in developing sustainable Population Based Cancer Registry and also provides an opportunity to increase coverage and expand it to other districts as well. Keywords: Challenges; Nepal; population based cancer registry; way forward

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