Why non-inferiority is more challenging than superiority?
2017 ◽
Vol 23
(6)
◽
pp. 790-791
◽
Demonstrating non-inferiority in clinical trials is usually more challenging than showing superiority. In multiple sclerosis (MS), non-inferiority trials are rarely designed since they would require prohibitive sample sizes. In this brief report, the reasons why non-inferiority trials are usually larger than superiority trials is explored.
2012 ◽
Vol 19
(4)
◽
pp. 466-474
◽
Keyword(s):
2020 ◽
2021 ◽
Vol 39
(15_suppl)
◽
pp. 1082-1082