Molar-incisor malformation: A case report and clinical considerations

2019 ◽  
Vol 46 (4) ◽  
pp. 343-348 ◽  
Author(s):  
Hui-Lin Luisa Neo ◽  
Eileen N Watt ◽  
Priti Acharya

Molar-incisor malformation (MIM) is a dental anomaly that has recently been presented in the literature. It features morphological root abnormalities affecting the permanent first molars, resulting in narrow, shortened or almost completely absent roots in patients who interestingly still present with clinically normal crowns. In some cases, this condition also involves the roots of the deciduous second molars in a similar manner and the maxillary central incisors may exhibit notching around the cervical region of the clinical crown. Root dysplasia of the permanent first molars compromises the long-term survival of these teeth and, in itself, presents a challenge when attempting to undertake any orthodontic treatment. This case report describes an incidental finding of a patient presenting with similar features to that of MIM, discusses the features and clinical implications of this newly discovered condition, and highlights the importance of undertaking a comprehensive radiological investigation before treatment.

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Satoshi Takamori ◽  
Hiroyuki Oizumi ◽  
Jun Suzuki ◽  
Katsuyuki Suzuki

Abstract Background Repeat pulmonary metastasectomy (PM) considerably improves the prognosis of patients with pulmonary metastases of osteosarcoma. Reports have demonstrated a significantly improved prognosis in patients who have undergone repeat metastasectomy for osteosarcoma; however, there have been no reports with more than six metastasectomies. Herein, we describe the long-term survival of a patient following resection of multiple tumors and other treatments for metastatic osteosarcoma. Case presentation A 28-year-old woman underwent extensive resection and postoperative adjuvant chemotherapy for right tibial sarcoma. Over the years, she developed repeated pulmonary metastases. First, 116 metastases were removed from the bilateral lungs. After that, multiple PMs of approximately 250 tumors and other treatments for deep metastatic lesions were performed. The patient died of the underlying disease 24 years after the primary surgery. Conclusions This case report demonstrates the long-term survival benefit of a multidisciplinary treatment centered on multiple metastasectomies.


2011 ◽  
Vol 2 (7) ◽  
pp. 206-207 ◽  
Author(s):  
Iraklis Perysinakis ◽  
Alexander Nixon ◽  
Aggeliki Katopodi ◽  
Emmanouil Tzirakis ◽  
Despoina Georgiadou ◽  
...  

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