Fetal Alcohol Syndrome: A Review

AAESPH Review ◽  
1977 ◽  
Vol 2 (3) ◽  
pp. 164-168
Author(s):  
Sam Delaney ◽  
Alice Hayden

In the paper the authors synthesize the information regarding the impact of alcohol consumption upon the offspring of alcoholic women, a condition more specifically known as Fetal Alcohol Syndrome. It is the intent of the authors that this information spur the development of a number of strategies aimed at primary and secondary preventative interventions for women who either have the disposition to the disease or have the disease, affecting them and their offspring.

2001 ◽  
Vol 7 (5) ◽  
pp. 648-649 ◽  
Author(s):  
Paul D. Connor

The primary focus of this volume is on the impact of alcohol on brain development. It is a perfect example of how research on both animals and humans can interact to produce very important findings. In the case of prenatal alcohol exposure, dialogue between animal and human researchers has proved to be very profitable for both lines of research. Initial observations by human researchers identified a syndrome of facial stigmata, physical malformations, and early behavioral disturbances that was related to maternal alcohol abuse during pregnancy. They gave this syndrome the name Fetal Alcohol Syndrome. However, human researchers were unable to state unequivocally that prenatal alcohol exposure was teratogenic to the fetus. Thus, they turned to animal researchers who were able to model Fetal Alcohol Syndrome in a variety of animals and to confirm the teratogenicity of alcohol on the developing fetus. The quarter century of studies of the damage caused by prenatal alcohol exposure is replete with such interactions between these two groups of researchers. Without the input and pioneering studies of animal researchers on the effects of prenatal alcohol exposure, human researchers would have much less understanding of the damage caused by alcohol exposure in utero or insights into possible treatment or remediation strategies for those damaged by alcohol exposure.


2014 ◽  
Vol 95 (2) ◽  
pp. 287-291
Author(s):  
A Yu Marianian

Alcohol consumption during pregnancy can cause serious birth defects and developmental disorders. The article reviews scientific literature describing modern conceptions of alcohol-associated teratogenicity. Problems of public awareness of alcohol negative impact on pregnancy and the fetus (particularly by informing women of reproductive age and pregnant women) are raised. Literature review revealed that there is a lack of information on fetal disorders associated with alcohol consumption by the mother. Nowadays, alcohol consumption in Russia is one of the highest in the world (15.8 liters per capita per year, including newborns, 2011), which is significantly higher than the absolute level of alcohol consumption associated with serious health risk for an individual and for the population as a whole. Awareness among women of reproductive age and pregnant women is very low. Therefore, it is necessary to inform and teach physicians screening methods of medical problems associated with alcohol intake and brief intervention strategies that will help to identify and inform women at risk for having children with fetal alcohol syndrome and fetal alcohol spectrum disorders and prevent the birth of mentally retarded children. The problem of fetal alcohol syndrome and the whole spectrum of fetal alcohol disorders is of great theoretical and practical significance in Russia.


2006 ◽  
Vol 34 (2) ◽  
pp. 342-351 ◽  
Author(s):  
Gregory Carey ◽  
Irving I. Gottesman

Combine the following: medicine, ethics, jurisprudence, behavioral genetics, and antisocial behavior (ASB). Given our level of scientific knowledge today, this combination is more akin to a cerebral smorgasbord than to a dinner where starter, entree, wine, and dessert are carefully chosen to complement one another. Hence, any survey of menus must be highly selective. We accept as a given that there is a noteworthy genetic influence on ASB no matter how it is defined. In terms of behavioral research, the magnitude of that genetic influence is substantial, but so is the impact from the environment, broadly defined to include pre-and post-natal, physical (e.g., anoxia, fetal alcohol syndrome, or crack) as well as psychosocial (e.g., quality of parenting, ethnic culture, or religion) elements.We will discuss some of the major issues raised by this fact of genetic influence that have most applicability to topics usually raised by observers outside of behavioral genetics.


Author(s):  
A. Yu. Marianian ◽  
A. N. Kalkova

Aim: to analyze and summarize the available data of studies aimed at deepening knowledge in the field of the influence of alcohol on the course of pregnancy, possible consequences; to study the prevalence of alcohol consumption by Russian women, as well as possible preventive measures.Materials and Methods. The results of Russian and foreign studies on the effect of alcohol on the fetus and pregnancy outcome, published in the international databases Scopus, Web of Science, PubMed/MEDLINE, Cochrane Library, have been analyzed. The search for scientific publications was limited to the period from 2012 to 2021. We used search queries in Russian ("alcohol", "pregnancy", "prevention", "fetus", "fetal alcohol syndrome") and English ("alcohol", "pregnancy", "prophylaxis", "fetus", "fetal alcohol syndrome").Results. The presented data analysis indicates an extremely negative effect of alcohol on the body of pregnant women, as well as on the health of our future generation. This article proves the importance of the problem, the need for further research on the mechanisms of fetal alcohol syndrome (FAS) and the development of effective prevention measures, possible methods of treatment, and assistance for alcoholic fetal syndrome. Today in Russia there is an acute lack of information on the real extent of the problem with maternal alcohol consumption during pregnancy. There is still no exact data on the prevalence of FAS in Russia.Conclusion. From the analysis of domestic and foreign literature, it can be concluded that the problem of preventing fetal alcohol syndrome is an urgent and unexplored problem in Russia. There is a need for doctors to conduct pregravid preparation of a married couple when they plan to conceive a healthy child. It is necessary to raise awareness and improve the quality of training for obstetricians and gynecologists in order to identify women with high risk factors for alcohol abuse and childbirth with FAS in the early stages of pregnancy management. It is also necessary to identify new or use already known biomarkers of maternal blood to verify excessive alcohol consumption during pregnancy.


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