scholarly journals Cognition in Stroke Rehabilitation and Recovery Research: Consensus-Based Core Recommendations From the Second Stroke Recovery and Rehabilitation Roundtable

2019 ◽  
Vol 33 (11) ◽  
pp. 943-950 ◽  
Author(s):  
Matthew W. McDonald ◽  
Sandra E. Black ◽  
David A. Copland ◽  
Dale Corbett ◽  
Rick M. Dijkhuizen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Cognitive Rehabilitation ◽  
Stroke Rehabilitation ◽  
Stroke Recovery ◽  
Future Research ◽  
Insufficient Evidence ◽  
Cognitive Assessments ◽  
Important Target

Cognitive impairment is an important target for rehabilitation as it is common following stroke, is associated with reduced quality of life and interferes with motor and other types of recovery interventions. Cognitive function following stroke was identified as an important, but relatively neglected area during the first Stroke Recovery and Rehabilitation Roundtable (SRRR I), leading to a Cognition Working Group being convened as part of SRRR II. There is currently insufficient evidence to build consensus on specific approaches to cognitive rehabilitation. However, we present recommendations on the integration of cognitive assessments into stroke recovery studies generally and define priorities for ongoing and future research for stroke recovery and rehabilitation. A number of promising interventions are ready to be taken forward to trials to tackle the gap in evidence for cognitive rehabilitation. However, to accelerate progress requires that we coordinate efforts to tackle multiple gaps along the whole translational pathway.

scholarly journals Cognition in stroke rehabilitation and recovery research: Consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable

2019 ◽  
Vol 14 (8) ◽  
pp. 774-782 ◽  
Author(s):  
Matthew W McDonald ◽  
Sandra E Black ◽  
David A Copland ◽  
Dale Corbett ◽  
Rick M Dijkhuizen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Cognitive Rehabilitation ◽  
Stroke Rehabilitation ◽  
Stroke Recovery ◽  
Future Research ◽  
Insufficient Evidence ◽  
Cognitive Assessments ◽  
Important Target

Cognitive impairment is an important target for rehabilitation as it is common following stroke, is associated with reduced quality of life and interferes with motor and other types of recovery interventions. Cognitive function following stroke was identified as an important, but relatively neglected area during the first Stroke Recovery and Rehabilitation Roundtable (SRRR I), leading to a Cognition Working Group being convened as part of SRRR II. There is currently insufficient evidence to build consensus on specific approaches to cognitive rehabilitation. However, we present recommendations on the integration of cognitive assessments into stroke recovery studies generally and define priorities for ongoing and future research for stroke recovery and rehabilitation. A number of promising interventions are ready to be taken forward to trials to tackle the gap in evidence for cognitive rehabilitation. However, to accelerate progress requires that we coordinate efforts to tackle multiple gaps along the whole translational pathway.

scholarly journals Cognitive rehabilitation interventions after stroke: protocol for a systematic review and meta-analysis of randomized controlled trials

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Qing Zhao ◽  
Xue Wang ◽  
Tao Wang ◽  
Adam A. Dmytriw ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cognitive Impairment ◽  
Randomized Controlled Trials ◽  
Cognitive Rehabilitation ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Post Stroke ◽  
Randomized Controlled

Abstract Background Stroke is the second leading cause of death worldwide, and 53.4% of stroke survivors suffer from post-stroke cognitive impairment. Post-stroke cognitive impairment can increase hospitalization rate and cost of care and decrease the quality of life of stroke patients. To date, multiple cognitive rehabilitation interventions have been tested in stroke populations with post-stroke cognitive impairment. However, the most efficacious intervention has not been established. This systematic review aims to compare the efficacy of cognitive rehabilitation interventions for patients with post-stroke cognitive impairment. Methods We will search MEDLINE, EMBASE, CENTRAL, PsycINFO, CINAHL, PubMed, and clinical trial registries to identify eligible randomized clinical trials with no restrictions in the date of publication and language. Studies conducted with patients aged 18 or over, with the presence of cognitive impairment after being diagnosed with stroke will be included. Studies will be restricted to randomized controlled trials comparing a cognitive rehabilitation intervention with another intervention. The primary outcome is any clinical changes in the general or specific cognitive domain (e.g., executive function, attention, memory, or perception). The secondary outcomes that will be collected include adverse effects (e.g., stroke, disability, or mortality) and quality of life. Two independent reviewers will assess articles to identify trials eligible for inclusion. Data extraction and risk of bias assessment of the included studies will also be done independently. Any discrepancies will be solved by discussion, or a third reviewer will be consulted if necessary. A meta-analysis will be carried out if appropriate. Discussion This systematic review for patients with post-stroke cognitive impairment will assess the efficacy of cognitive rehabilitation interventions. And our results will help clinical decision-making and support the development of clinical practice guidelines. Trial registration Systematic review registration: PROSPERO CRD42020173988

Stroke rehabilitation and recovery

2021 ◽  
Vol 82 (9) ◽  
pp. 1-7
Author(s):  
Alifa Isaacs-Itua ◽  
Sancho Wong
Keyword(s):  
Quality Of Life ◽  
Stroke Rehabilitation ◽  
Stroke Recovery ◽  
Improve Quality ◽  
Post Stroke ◽  
Communication Impairments

Stroke is the UK's leading cause of disability. Stroke rehabilitation can maximise recovery and improve quality of life. This article discusses some post-stroke impairments, including hemiplegia, dysphagia, communication impairments and neglect, and how rehabilitation can address these. Developing techniques of adaptation or compensation is vital, since the extent of stroke recovery is dependent on successful neuroplasticity, with healthy neurons adapting to compensate for damaged ones.

scholarly journals Managing depressive symptoms in people with mild cognitive impairment and mild dementia with a multicomponent psychotherapy intervention: a randomized controlled trial

2020 ◽  
pp. 1-15 ◽  
Author(s):  
Johanne B. Tonga ◽  
Jūratė Šaltytė Benth ◽  
Espen A. Arnevik ◽  
Katja Werheid ◽  
Maria S. Korsnes ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Randomized Controlled Trial ◽  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Cognitive Rehabilitation ◽  
Controlled Trial ◽  
Control Group ◽  
Reminiscence Therapy ◽  
Randomized Controlled

Abstract Objective: To evaluate the feasibility and effectiveness of the CORDIAL program, a psychosocial intervention consisting of cognitive behavioral therapy (CBT), cognitive rehabilitation, and reminiscence to manage depressive symptoms for people with mild cognitive impairment (MCI) or dementia. Design: We conducted a randomized controlled trial, based on a two-group (intervention and control), pre-/post-intervention design. Setting: Participants were recruited from five different old age psychiatry and memory clinics at outpatients’ hospitals. Participants: Hundred and ninety-eight people with MCI or early-stage dementia were included. Intervention: The intervention group (n = 100) received 11 individual weekly sessions of the CORDIAL program. This intervention includes elements from CBT, cognitive rehabilitation, and reminiscence therapy. The control group (n = 98) received treatment-as-usual. Measurements: We assessed Montgomery–Åsberg Depression Rating Scale (MADRS) (main outcome), Neuropsychiatric Inventory Questionnaire, and Quality of Life in Alzheimer’s disease (secondary outcomes) over the course of 4 months and at a 10-month follow-up visit. Results: A linear mixed model demonstrated that the depressive symptoms assessed by MADRS were significantly more reduced in the intervention groups as compared to the control group (p < 0.001). The effect persisted for 6 months after the intervention. No significant differences between groups were found in neuropsychiatric symptoms or quality of life. Conclusion: Our multicomponent intervention, which comprised 11 individual sessions of CBT, cognitive rehabilitation, and reminiscence therapy, reduced depressive symptoms in people with MCI and dementia.

Targeted Treatment for Cognitive Impairment Associated with Cancer and Cancer Treatment

2017 ◽  
Author(s):  
Shelli R. Kesler ◽  
Jeffrey S. Wefel
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Health Behavior ◽  
Cancer Treatment ◽  
Cancer Patients ◽  
Treatment Adherence ◽  
Management Strategies ◽  
Future Research ◽  
Cognitive Difficulty

Cognitive difficulty is one of the most common quality-of-life complaints among cancer patients and survivors. Cancer-related cognitive impairment (CRCI) is a common problem among cancer patients and survivors that extends disease-related morbidity; reduces quality of life; interferes with treatment adherence; and is a significant predictor of health behavior, disease progression, and survival. Several emerging management strategies for CRCI show promise for preventing and/or ameliorating CRCI. This chapter describes the incidence, symptoms, and putative mechanisms of CRCI and then discusses potential approaches for addressing CRCI. The focus of the interventions discussed in this chapter is on directions for future research that will potentially lead to widely accessible, effective, and ecologically valid approaches.

scholarly journals OPTIMISM, QUALITY OF LIFE, AND COGNITION IN RECENT NURSING HOME RESIDENTS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S113-S113
Author(s):  
Diana DiGasbarro ◽  
Kimberly Van Haitsma ◽  
Suzanne Meeks ◽  
Benjamin T Mast
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Nursing Home ◽  
Cognitive Impairment ◽  
Nursing Home Residents ◽  
Dispositional Optimism ◽  
Well Being ◽  
Future Research ◽  
The Relationship

Abstract Dispositional optimism may be an important resource for well-being across the lifespan. However, the relationship between optimism and quality of life in recent nursing home residents with and without cognitive impairment has not been examined. The aim of this study is to fill this gap in a sample of 66 older adults with a mean age of 74.59 years old (SD=10.37) who were admitted to a nursing home within the previous 30 days. Sixty older adults completed measures of cognition, quality of life, and optimism, and thus were included in analysis for the current study. Participants were split into groups based on the presence or absence of cognitive impairment, and linear regressions were conducted to examine the relationship between optimism and quality of life. In recent nursing home residents without cognitive impairment (n=30), optimism did not predict quality of life and accounted for a very small amount of variance (R2=.042, p=.280). However, in recent nursing home residents with cognitive impairment (n=32), optimism accounted for 20.9% of the variance in quality of life (R2=.209, p=.009). Higher levels of optimism were associated with better quality of life. Future research should explore why a stable trait like dispositional optimism is a stronger predictor of quality of life in recent nursing home residents with cognitive impairment compared to those without cognitive impairment. This line of research would be synergistic with emerging research on the identification and encouragement of strengths in older adults with cognitive impairment.

Geriatric Nephrology Syndromes and Assessment and Management of Cognitive Impairment

2020 ◽  
pp. 188-196
Author(s):  
Edwina A. Brown ◽  
Osasuyi Iyasere
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Kidney Disease ◽  
Management Strategies ◽  
Research Priorities ◽  
The Elderly ◽  
Future Research ◽  
Geriatric Syndromes ◽  
Geriatric Nephrology

The demographics of the renal population have evolved, such that the elderly are the fastest growing group. Consequently, the multidisciplinary renal team often encounters clinical issues associated with advancing age. In this chapter, frailty, falls, and cognitive impairment are discussed as underrecognized geriatric syndromes in patients with chronic kidney disease. A case history illustrates how these syndromes tend to co-exist and affect quality of life and survival. The risk factors, management strategies, and future research priorities are discussed, recognizing the importance of a multidisciplinary approach to the management of elderly patients with kidney disease.

scholarly journals Cognitive Rehabilitation Interventions After Stroke: Protocol for a Systematic Review and Meta-analysis of Randomized Controlled Trials

2020 ◽  
Author(s):  
Qing Zhao ◽  
Xue Wang ◽  
Tao Wang ◽  
Adam A. Dmytriw ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cognitive Impairment ◽  
Randomized Controlled Trials ◽  
Cognitive Rehabilitation ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Post Stroke ◽  
Randomized Controlled

Abstract Background: Stroke is the second leading cause of deaths worldwide, and 53.4% of the stroke survivors suffer from post-stroke cognitive impairment. Post-stroke cognitive impairment can increase hospitalization rate and cost of care, and decrease the quality of life of stroke patients. To date, multiple cognitive rehabilitation interventions have been tested in stroke populations with post-stroke cognitive impairment. However, the most efficacious intervention has not been established. This systematic review aims to compare the efficacy of cognitive rehabilitation interventions for patients with post-stroke cognitive impairment.Methods: We will search MEDLINE, EMBASE, CENTRAL, PsycINFO, CINAHL, PubMed and clinical trial registries to identify eligible randomized clinical trials with no restrictions in the date of publication and language. Studies conducted with patient aged 18 or over, with the presence of cognitive impairment after being diagnosed with stroke will be included. Studies will be restricted to randomized controlled trials comparing a cognitive rehabilitation intervention with another intervention. The primary outcome is any clinical changes in general or specific cognitive domain (e.g. executive function, attention, memory or perception). The secondary outcomes that will be collected include adverse effects (e.g. stroke, disability or mortality) and quality of life. Two independent reviewers will assess articles to identify trials eligible for inclusion. Data extraction and risk of bias assessment of the included studies will also be done independently. Any discrepancies will be solved by discussion, or a third reviewer will be consulted if necessary. A meta-analysis will be carried out if appropriate.Discussion: This systematic review for patients with post-stroke cognitive impairment will assess efficacy of cognitive rehabilitation interventions. And our results will help clinical decision-making and support the development of clinical practice guidelines.Systematic review registration: PROSPERO CRD42020173988

scholarly journals Cognitive rehabilitation interventions after stroke: protocol for a systematic review and meta-analysis of randomized controlled trials

2021 ◽  
Author(s):  
Qing Zhao ◽  
Xue Wang ◽  
Tao Wang ◽  
Adam A. Dmytriw ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cognitive Impairment ◽  
Randomized Controlled Trials ◽  
Cognitive Rehabilitation ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Post Stroke ◽  
Randomized Controlled

Abstract Background: Stroke is the second leading cause of death worldwide, and 53.4% of stroke survivors suffer from post-stroke cognitive impairment. Post-stroke cognitive impairment can increase hospitalization rate and cost of care, and decrease the quality of life of stroke patients. To date, multiple cognitive rehabilitation interventions have been tested in stroke populations with post-stroke cognitive impairment. However, the most efficacious intervention has not been established. This systematic review aims to compare the efficacy of cognitive rehabilitation interventions for patients with post-stroke cognitive impairment.Methods: We will search MEDLINE, EMBASE, CENTRAL, PsycINFO, CINAHL, PubMed, and clinical trial registries to identify eligible randomized clinical trials with no restrictions in the date of publication and language. Studies conducted with patients aged 18 or over, with the presence of cognitive impairment after being diagnosed with stroke will be included. Studies will be restricted to randomized controlled trials comparing a cognitive rehabilitation intervention with another intervention. The primary outcome is any clinical changes in the general or specific cognitive domain (e.g. executive function, attention, memory, or perception). The secondary outcomes that will be collected include adverse effects (e.g. stroke, disability, or mortality) and quality of life. Two independent reviewers will assess articles to identify trials eligible for inclusion. Data extraction and risk of bias assessment of the included studies will also be done independently. Any discrepancies will be solved by discussion, or a third reviewer will be consulted if necessary. A meta-analysis will be carried out if appropriate.Discussion: This systematic review for patients with post-stroke cognitive impairment will assess the efficacy of cognitive rehabilitation interventions. And our results will help clinical decision-making and support the development of clinical practice guidelines.Systematic review registration: PROSPERO CRD42020173988

Invisible Effects of Chemotherapy

2017 ◽  
Vol 41 (S1) ◽  
pp. S668-S668
Author(s):  
D. Brandão ◽  
T. Assunção ◽  
H. Almeida
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Cognitive Rehabilitation ◽  
Cognitive Change ◽  
Behavioural Therapy ◽  
Current Evidence ◽  
Microvascular Damage ◽  
Competing Interest ◽  
The Impact

IntroductionChemotherapy is an essential component in the treatment and alleviation of oncological diseases. To your application are associated, as well as systemic effects, cognitive impairment in patients. These changes have received increasing attention due to the impact on quality of life of cancer survivors.ObjectivesThis study aims to evaluate the current evidence on the association between chemotherapy and cognitive impairment in cancer patients, especially in the areas affected cognitive function, possible mechanisms of action and consequences on the quality of life of these patients and the importance of identifying strategies intervention in order to minimize these effects.MethodsWe conducted a literature review from literature articles addressing this topic with use of databases: Medline and Pubmed. The following keywords were used: “chemobrain”, “cognitive dysfunction”, “chemotherapy”.ResultsAlthough some states have not found differences, several studies have shown that chemotherapy has implications cognitively. Underlying etiology remains unknown, and proposed several mechanisms to explain these changes: neurotoxicity, microvascular damage and inflamamatory response. Cognitive impairment has significant implications in the daily life of patients both personally, socially and labour. The therapeutic approach focuses on the patient and family education, coping strategies, cognitive rehabilitation and cognitive behavioural therapy.ConclusionsIt is vital to educate patients about the possibility of cognitive change as effect of chemotherapy as well as health professionals in the early identification of these changes. It is essential developing specific intervention strategies to improve the quality of life of the oncologic patient during and after treatment.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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