Lithium Intoxication Mimicking Clinical and Electrographic Features of Status Epilepticus: A Case Report and Review of the Literature

2003 ◽  
Vol 34 (1) ◽  
pp. 28-31 ◽  
Author(s):  
M. Gansaeuer ◽  
T. M. Alsaadi
Keyword(s):  
Case Report ◽  
Status Epilepticus ◽  
Plasma Level ◽  
Mental Status ◽  
Plasma Levels ◽  
Mental Function ◽  
Review Of The Literature ◽  
Lithium Intoxication ◽  
Eeg Abnormalities ◽  
Previously Treated

A 58-year-old patient who was somnolent, distractible and confused is presented. She was previously treated with lithium, and a plasma level was mildly elevated at 1.7 mmol/l (normal 0.5–1.5 mmol/l). The EEG was suggestive of electrographic status epilepticus. Following treatment with i.v. lorazepam, neither mental status nor EEG abnormalities improved. She had a full recovery of mental function and markedly improved EEG findings following discontinuation of lithium. The EEG is an effective tool for diagnosing lithium neurotoxicity in patients with normal or mildly elevated lithium plasma levels. However, caution is needed before making an assumption of status epilepticus.

scholarly journals Phenytoin Toxicity Treatment with Haemodialysis in Epilepsy due to Glioblastoma Multiforme: Case Report and Review of the Literature

2019 ◽  
Vol 11 (3) ◽  
pp. 344-350 ◽  
Author(s):  
Karishma Sharma ◽  
Aditi Vakil ◽  
Ahmed Sokwala ◽  
Dilraj Sokhi
Keyword(s):  
Urinary Tract Infection ◽  
Case Report ◽  
Status Epilepticus ◽  
Glioblastoma Multiforme ◽  
Review Of The Literature ◽  
Level Of Consciousness ◽  
Symptomatic Epilepsy ◽  
Previously Treated ◽  
Phenytoin Toxicity ◽  
Fatal Complications

Phenytoin is one of the most commonly used anticonvulsants in the developing world, but lack of monitoring and concurrent medications can easily lead to toxicity. We report the case of a 35-year-old female on phenytoin for symptomatic epilepsy due to previously treated glioblastoma multiforme, who presented with status epilepticus 1 week after being treated for a urinary tract infection. She was loaded with phenytoin and levetiracetam as per emergency protocol but had a persistently low level of consciousness, and her preloading phenytoin level result came back in the toxic range. She was managed conservatively, but after 4 days with no change she was dialyzed and her level of consciousness improved within 24 h, allowing for safe discharge home shortly after. Our case illustrates the option of haemodialysis in phenytoin-toxic patients who do not improve with conservative measures or who may need urgent reduction due to potentially fatal complications of phenytoin toxicity.

Norovirus Causes Pediatric Encephalopathy and Status Epilepticus: A Case Report and Review of the Literature

2021 ◽  
Author(s):  
Gabriela Tantillo ◽  
Navyamani Kagita ◽  
Maite LaVega-Talbott ◽  
Anuradha Singh ◽  
David Kaufman
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Status Epilepticus ◽  
Magnetic Resonance ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Common Cause ◽  
Diffusion Restriction ◽  
Neurologic Impairment ◽  
Norovirus Gastroenteritis

AbstractNorovirus is a common cause of acute gastroenteritis outbreaks worldwide. The disease can present with varying degrees of neurologic impairment from benign convulsions to rare cases of severe encephalopathy. We describe a case report of a North American infant who presented with norovirus gastroenteritis, status epilepticus, severe encephalopathy, and abnormal but reversible diffusion restriction changes on magnetic resonance imaging of brain.

A rare cause of status epilepticus; alpha lipoic acid intoxication, case report and review of the literature

2015 ◽  
Vol 19 (6) ◽  
pp. 730-732 ◽  
Author(s):  
Orkun Tolunay ◽  
Tamer Çelik ◽  
Mustafa Kömür ◽  
Ali Emre Gezgin ◽  
Musa Soner Kaya ◽  
...  
Keyword(s):  
Case Report ◽  
Status Epilepticus ◽  
Lipoic Acid ◽  
Alpha Lipoic Acid ◽  
Review Of The Literature

Pediatric Metronidazole-Induced Encephalopathy: A Case Report and Review of the Literature

2020 ◽  
Author(s):  
Alberto M. Cappellari ◽  
Donata Rossetti ◽  
Sabrina Avignone ◽  
Elisa Scola ◽  
Antonio Di Cesare
Keyword(s):  
Case Report ◽  
Status Epilepticus ◽  
Antimicrobial Drug ◽  
Adult Patients ◽  
Nonconvulsive Status Epilepticus ◽  
Toxic Encephalopathy ◽  
Review Of The Literature ◽  
The Common

AbstractMetronidazole-induced encephalopathy is a rare toxic encephalopathy secondary to the common use to this antimicrobial drug. It has been reported mainly in adult patients but only rarely in children. Owing to possible devastating complication of this disease, clinicians should have a higher index of suspicion for encephalopathic patients on metronidazole therapy. Here, we report a 5-month-old infant with metronidazole-induced encephalopathy presenting with nonconvulsive status epilepticus. A review of the literature in pediatric, as well as adult metronidazole-induced encephalopathy, is also provided.

scholarly journals Cortico-basal ganglionic degeneration a case report

1992 ◽  
Vol 50 (2) ◽  
pp. 216-218
Author(s):  
J. Teotônio de Oliveira ◽  
Francisco E. Cota Cardoso
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Mental Status ◽  
Sensory Impairment ◽  
Pathological Features ◽  
Review Of The Literature ◽  
Ideomotor Apraxia ◽  
Brazilian Patient ◽  
Male Displays ◽  
Clinical And Pathological Features

The case of a Brazilian patient with cortico-basal ganglionic degeneration (CBGD) is presented. Since three years ago, a 71-year old male displays asymmetric ideomotor apraxia, gait apraxia, cortical sensory impairment, myoclonus, limp dystonia and rigidity. His mental status is spared. There is neither consanguinity nor similar cases in his family. The differential diagnosis of CBGD is discussed. A brief review of the literature is made stressing the clinical and pathological features of CBGD. This disease is poorly known and probably underdiagnosed. Its diagnosis can be safely made based on clinical grounds.

scholarly journals A spicy status: Synthetic cannabinoid (spice) use and new-onset refractory status epilepticus—A case report and review of the literature

2017 ◽  
Vol 5 ◽  
pp. 2050313X1774520 ◽  
Author(s):  
Marc-Alain Babi ◽  
Christopher P Robinson ◽  
Carolina B Maciel
Keyword(s):  
Case Report ◽  
Status Epilepticus ◽  
Synthetic Cannabinoids ◽  
Refractory Status Epilepticus ◽  
Synthetic Cannabinoid ◽  
Severe Toxicity ◽  
Acute Psychosis ◽  
Review Of The Literature ◽  
Refractory Status ◽  
New Onset

Synthetic cannabinoids refer to a wide variety of chemicals engineered to bind cannabinoid receptors (CB1 and CB2) and mimic the effects of delta-9-tetrahydrocanabinol. The potential for severe toxicity and limited in vivo data make synthetic cannabinoid intake an important public health and safety concern. Neurologic toxidromes associated with their use include mental status changes, panic attacks, memory distortions, acute psychosis (e.g. paranoia, delusional thoughts), disorganized behavior, and suicidal and homicidal thoughts. Systemic complications include vomiting, sinus tachycardia, myocardial infarction, and acute kidney injury. Seizures are common; however, status epilepticus is not widely reported. In this case report, we describe a patient who developed acute psychosis and new-onset refractory status epilepticus necessitating emergent neurological life-support and prolonged admission to an intensive care unit following abuse of synthetic cannabinoids. We include a brief review of the literature to prepare the treating clinician for the broad clinical spectrum of this increasingly common intoxication.

Ecg Changes in Pure Imipramine Overdose as Function of Plasma Level*

1978 ◽  
Vol 23 (8) ◽  
pp. 573-577 ◽  
Author(s):  
K. Reed ◽  
H.R. Mckim
Keyword(s):  
Cardiac Arrest ◽  
Case Report ◽  
Plasma Level ◽  
Plasma Levels ◽  
Tricyclic Antidepressants ◽  
Lethal Effect ◽  
Acute Management ◽  
Relative Toxicity ◽  
Ecg Changes ◽  
Therapeutic Doses

ECG changes occur with therapeutic doses of tricyclic antidepressants and cardiovascular conduction alteration is the lethal effect in overdoses on these drugs. These ECG changes depend on the plasma level and metabolism of the particular antidepressant. Information about the relative toxicity and metabolism characteristics can be obtained by studying overdoses if the attempt simply involves one tricyclic and no other drug ingestion. Such a case report involving a known quantity of imipramine is presented. The early toxic signs leading to cardiac arrest and the recovery from coma are discussed. The ECG along with corresponding plasma levels of imipramine and its metabolite desmethylimipramine are given as a function of time after ingestion. The relative toxicity of these metabolites and the use of anticholinesterase in the acute management is considered.

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