scholarly journals Computational Fluid Dynamics for Brain Circulation and Aneurysm with Therapeutic Devices

2004 ◽  
Vol 10 (2_suppl) ◽  
pp. 108-112 ◽  
Author(s):  
K. Fukasaku ◽  
M. Negoro ◽  
H. Iwase ◽  
K. Yokoi ◽  
R. Himeno

We analysed fluid dynamics at brain arteries having multiple inflow and out flow like Willis ring based on clinical imaging modalities. In addition, we analysed fluid dynamics with therapeutic devices like coils and stents to simulate their influences to blood flow. 3D CTA and MRA obtained three-dimensional structures of the brain vessels. The centreline was obtained from the three dimensional structure. Diameter of the blood vessels was measured by 3D CTA/MRA then smooth surfaced blood vessel models were created. For the fluid analysis, we developed a home brew software which can display parameters such as streamline, etc. In addition, our CFD (computational fluid dynamics) software can work in collaboration with a CAD (computer aided design) software which we also developed (VCAD: Volume CAD). So, therapeutic devices such as coils, balloons and stents could be placed in the models and CFD analysis could be performed placing devices in the models. The flow pattern in the complicated vascular structure could be calculated such as Willis ring which has multiple inputs like ICA, VA and multiple outlets like MCA and PCA with communicating arteries. CFD with therapeutic devices could also analysed with our system.

2021 ◽  
Vol 55 (5) ◽  
pp. 94-108
Author(s):  
Harlysson W. S. Maia ◽  
Said Mounsif ◽  
Jassiel V. Hernández-Fontes ◽  
Rodolfo Silva

Abstract This paper extends the work of Maia and Said (“Analysis for Resistance Reduction of an Amazon School Boat through Hull Shape Modification Utilizing a CFD Tool,” 2019), proposing the optimization of a school boat hull using genetic algorithms and computational fluid dynamics (CDF) simulations. The study examines a school boat used for the transportation of children to schools in riverine communities of the Brazilian Amazon. The optimization was focused on reducing the hydrodynamic hull resistance by modifying the hull lines, using the NSGA-II (non-dominated sorting genetic algorithm II) algorithm in the CAD (computer aided design) CAESES environment. The objective of the study was to reduce the resistance coefficients: C wp (wave profile) and C wp trans (transverse wave profile), thus reducing the total resistance coefficient (C t) and the generated wave amplitude. Pressure distributions and flow lines were then evaluated to obtain an optimal modified hull with reduced wave emission (lower wave resistance) and, consequently, lower forward resistance. The proposed methodology resulted in a maximum reduction of 5% in the total resistance coefficient C t and in the identification of a trend of geometric variation of the hull for investigation in further studies.


Author(s):  
Xu Zhang ◽  
David J. J. Toal ◽  
Neil W. Bressloff ◽  
Andy J. Keane ◽  
Frederic Witham ◽  
...  

The following paper presents an overview of the Prometheus design system and its applications to gas turbine combustor design. Unlike a traditional “optimizer-centric” method, Prometheus aims to reduce both the level of workflow complexity and rework by taking a more “geometry-centric” approach to design optimization by shifting the control of script generation away from the optimization program to the computer aided design (CAD) package. Prometheus therefore enables significant geometry changes to be automatically reflected in all subsequent scripts necessary for the analysis of a combustor. Prometheus’ current capabilities include automatic fluid volume generation and aero-thermal and thermo-acoustic network generation as well as automatic mesh and computational fluid dynamics (CFD) script generation.


Author(s):  
Muthuminal R.

In past decades, for developing a site, engineers used the process of creating a scale model in order to determine their behaviour and to sketch the details collected manually using the drafting process, which behaves as a referring material during the construction of structures. Due to the boom in technology and limitations in drafting, the drawings have been digitized using computer-aided design (CAD) software as a two-dimensional structure (2D). Currently, these drawings are detailed as a three-dimensional structure (3D) that is briefly noted as 3D modelling. Three-dimensional site modelling is an active area that is involved in research and development of models in several fields that has been originated from the scale modelling. In this chapter, the topic 3D site modelling in civil engineering is discussed. First of all, the basic concepts of scale modelling, architectural modelling, and structural modelling are discussed. Then the concept of virtual-based 3D site modelling, its importance, benefits, and steps involved in site modelling are briefed.


2021 ◽  
Vol 27 (2) ◽  
pp. 139-148
Author(s):  
Yousef Abu-Zidan ◽  
Kate Nguyen ◽  
Priyan Mendis ◽  
Sujeeva Setunge ◽  
Hojjat Adeli

The novel coronavirus (SARS-CoV-2) has spread at an unprecedented rate, resulting in a global pandemic (COVID-19) that has strained healthcare systems and claimed many lives. Front-line healthcare workers are among the most at risk of contracting and spreading the virus due to close contact with infected patients and settings of high viral loads. To provide these workers with an extra layer of protection, the authors propose a low-cost, prefabricated, and portable sanitising chamber that sprays individuals with sanitising fluid to disinfect clothing and external surfaces on their person. The study discusses computer-aided design of the chamber to improve uniformity of sanitiser deposition and reduce discomfort due to excessive moisture. Advanced computational fluid dynamics is used to simulate the dispersion and deposition of spray particle, and the resulting wetting pattern on the treated person is used to optimise the chamber design.


Author(s):  
Avinash T

Abstract: The objective of the present study is to design and analyze semi-tangential ogive bullets using simulatation software such as Computer-aided design & Computational Fluid Dynamics (CFD). It is observed that been a quite steady increase in the bullet research design in the past few decades. The nose section of ballistic bullet is the most important part of the design process. Hence design optimizations are achieved by adjusting the bullet's form to improve precision and stability by reducing its drag force. CFD is the study used to verify the findings. Since provides most accurate results. It is observed that present study optimizes the behavior of the at M= 2.5. This present work shows the flow of air around the bullet surface providing pressure & velocity contours at every segment. The Various parametric studies over bullet model are drag co-efficient, ballistic coefficient and turbulence viscosity are plotted’.


Micromachines ◽  
2019 ◽  
Vol 10 (4) ◽  
pp. 256
Author(s):  
Woo Young Choi ◽  
Gyuhan Yoon ◽  
Woo Young Chung ◽  
Younghoon Cho ◽  
Seongun Shin ◽  
...  

A full three-dimensional technology-computer-aided-design-based reliability prediction model was proposed for dynamic random-access memory (DRAM) storage capacitors. The model can be used to predict the time-dependent dielectric breakdown as well as leakage current of a state-of-the-art DRAM storage capacitor with a complex three-dimensional structure.


Physiology ◽  
1998 ◽  
Vol 13 (4) ◽  
pp. 182-189 ◽  
Author(s):  
Amedeo Caflisch ◽  
Rudolf Wälchli ◽  
Claus Ehrhardt

Computer-aided ligand design is an active, challenging, and multidisciplinary research field that blends knowledge of biochemistry, physics, and computer sciences. Whenever it is possible to experimentally determine or to model the three-dimensional structure of a pharmacologically relevant enzyme or receptor, computational approaches can be used to design specific high-affinity ligands. This article describes methods, applications, and perspectives of computer-assisted ligand design.


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