scholarly journals The Current Status of Treatment Strategies for Cerebral Aneurysms in Nagoya University and Affiliated Hospitals Based on a Questionnaire Survey

2007 ◽  
Vol 13 (1_suppl) ◽  
pp. 39-43
Author(s):  
T. Izumi ◽  
S. Miyachi ◽  
K. Hattori ◽  
H. Iizuka ◽  
Y. Nakane ◽  
...  
Keyword(s):  
Treatment Strategies ◽  
Cerebral Aneurysms ◽  
Treatment Method ◽  
Current Status ◽  
Low Grade ◽  
Anterior Circulation ◽  
International Subarachnoid Aneurysm Trial ◽  
Sedative Drugs ◽  
Almost All ◽  
Anterior Circulation Aneurysms

We investigated differences in the treatment strategies for ruptured aneurysms among 26 hospitals affiliated with Nagoya University and any changes in those strategies based on responses to a questionnaire. We also surveyed the data concerning patients with a ruptured aneurysm collected from our affiliated hospitals between 2001 and 2002. In half of the institutes, angiography is performed immediately after an urgent medical examination, there are only five hospitals (20%) which have a basic policy of terminating the angiography within three to six hours after onset. In half of the institutes, the timing of the treatment also depends on the location of the aneurysm. In particular, the treatment for vertebro-basilar aneurysms tends to be done the next day or later. Low-grade subarachnoid hemorrhage (SAH) patients with mild symptoms tended not to be given any sedative drugs (46%), while patients with SAH in some institutes were sedated without informed consent regardless of the severity. The main treatment method for most anterior circulation aneurysms was clipping. Concerning aneurysms located in the posterior circulation and the origin of the ophthalmic artery, clipping and coiling were equally selected. Almost all the hospitals (92%) responded that their treatment strategy had not changed even after the report of the International Subarachnoid Aneurysm Trial (ISAT). There is a great deal of difference in treatment strategies and indications among institutions. In particular, institutions without neuroendovascular interventionists (NETists) frequently persist in the conventional policy, making it urgently necessary to bring NETists up-to-date on the latest advance in endovascular treatment.

OLFACTORY DYSFUNCTION AFTER IPSILATERAL AND CONTRALATERAL PTERIONAL APPROACHES FOR CEREBRAL ANEURYSMS

Neurosurgery ◽  
2009 ◽  
Vol 65 (4) ◽  
pp. 727-732 ◽  
Author(s):  
Jaechan Park ◽  
Sun-Ho Lee ◽  
Dong-Hun Kang ◽  
Jung-Soo Kim
Keyword(s):  
Aneurysmal Subarachnoid Hemorrhage ◽  
Cerebral Aneurysms ◽  
Olfactory Dysfunction ◽  
Anterior Communicating Artery ◽  
Pterional Approach ◽  
Anterior Circulation ◽  
Related Risk ◽  
Lateral Distance ◽  
Contralateral Pterional Approach ◽  
Anterior Circulation Aneurysms

Abstract OBJECTIVE This study investigated olfactory dysfunction after using a contralateral or ipsilateral pterional approach for anterior circulation aneurysms and related risk factors. METHODS This study included 189 patients who experienced an aneurysmal subarachnoid hemorrhage and in whom a pterional approach was used, including a contralateral pterional approach (12 patients), a pterional approach for an anterior communicating artery (AComA) aneurysm (70 patients), and an ipsilateral pterional approach for aneurysms of the anterior circulation, excluding the AComA (107 patients). In addition to questionnaires on olfactory function, Sniffin' Sticks tests were performed 12 to 38 months after the operation. RESULTS The incidence of olfactory dysfunction was high: 58% (7 of 12) with a contralateral pterional approach, 14% (10 of 70) with a pterional approach for an AComA aneurysm, and 4% (4 of 107) with an ipsilateral pterional approach for aneurysms of the anterior circulation, except for the AComA. In addition, patients 55 years and older had a higher incidence of olfactory dysfunction. Among the 12 patients in whom the contralateral pterional approach was used, 5 (42%) were anosmic and 2 (17%) were hyposmic. The incidence of olfactory dysfunction was also significantly higher at ages 55 years and older. The size and location of the contralateral aneurysm, if small (<1 cm) and located within a 3-cm lateral distance from the midline, were not found to influence the incidence. CONCLUSION A higher incidence of olfactory dysfunction was found in those patients in whom a contralateral pterional approach and a pterional approach for an AComA aneurysm were used. Another major risk factor was an age of 55 years and older.

scholarly journals Transient Adenosine-Induced Asystole During the Surgical Treatment of Anterior Circulation Cerebral Aneurysms: Technical Note

2010 ◽  
Vol 67 (suppl_2) ◽  
pp. ons461-ons470 ◽  
Author(s):  
Ciaran J. Powers ◽  
David R. Wright ◽  
David L. McDonagh ◽  
Cecil O. Borel ◽  
Ali R. Zomorodi ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Cerebral Aneurysms ◽  
Technical Note ◽  
Aortic Aneurysms ◽  
Anterior Circulation ◽  
Aneurysm Neck ◽  
Short Period ◽  
Delayed Complication ◽  
Patient Responses ◽  
Anterior Circulation Aneurysms

Abstract BACKGROUND: Transient adenosine-induced asystole is a reliable method for producing a short period of relative hypotension during surgical and endovascular procedures. Although the technique has been described in the endovascular treatment of brain arteriovenous malformations, aortic aneurysms, and posterior circulation cerebral aneurysms, little description of its use in anterior circulation aneurysms is available. OBJECTIVE: To assess the benefits of adenosine-induced transient asystole in complex anterior circulation aneurysms, to describe our experience in selected cases, and to provide the first experience of the use of adenosine in anterior circulation aneurysms. METHODS: The adenosine-induced cardiac arrest protocol allows us to titrate the duration of cardiac arrest on the basis of individual patient responses. The operative setup is the same as with all aneurysm clippings, with the addition of the placement of transcutaneous pacemakers as a precaution for prolonged bradycardia or asystole. Escalating doses of adenosine are given to determine the approximate dose that results in 30 seconds of asystole. When requested by the surgeon, the dose of adenosine is administered for definitive dissection and clipping. We present 6 cases in which this technique was used. RESULTS: The use of transient adenosine-induced asystole provided excellent circumferential visualization of the aneurysm neck and safe clip application. All patients did well neurologically and suffered no evidence of perioperative cerebral ischemia or delayed complication from the use of adenosine itself. CONCLUSION: Transient adenosine-induced asystole is a safe and effective technique in select circumstances that may aid in safe and effective aneurysm clipping. Along with the traditional techniques of brain relaxation, skull base approaches, and temporary clipping, adenosine-induced asystole facilitates circumferential visualization of the aneurysm neck and is another technique available to cerebrovascular surgeons.

scholarly journals Microsurgical clipping of the anterior circulation aneurysms

2018 ◽  
Vol 20 (4) ◽  
pp. 409-414
Author(s):  
Carlos Eduardo Da Silva ◽  
Paulo Eduardo Peixoto De Freitas ◽  
Alicia Del Carmen Becerra Romero ◽  
Fáberson João Mocelin Oliveira ◽  
Márcio Aloisio Bezerra Cavalcanti Rockenbach ◽  
...  
Keyword(s):  
Relevant Literature ◽  
Cerebral Aneurysms ◽  
Series Data ◽  
Anterior Communicating Artery ◽  
Anterior Circulation ◽  
Ruptured Aneurysms ◽  
Microsurgical Clipping ◽  
The Mean ◽  
Anterior Circulation Aneurysms

Introduction: The authors present the analysis of the microsurgical clipping of 100 cerebral aneurysms of the anterior circulation and compare the series data with the literature. Methods: Eighty-eight patients presenting with 100 anterior circulation aneurysms operated on microsurgical techniques between 2002 and 2008 by the first author (CES) were retrospectively reviewed. Results: A total of 88 patients with 100 aneurysms of the anterior circulation were treated in a six years period. Fifty eight female (66%) and thirty male (34%) with nine patients (10.2%) presenting with multiple aneurysms. The mean age was 52 years (range from 26 to 76 years). Eighty five percent of the cases were ruptured aneurysms. The mean follow-up was 52.4 months (range from 5 to 76 months). The topography of the aneurysms was distributed as it follows: Anterior communicating artery (ACoA) 25%; posterior communicating artery (p-comm) 29%; middle cerebral artery (MCA) 27%; paraclinoidal aneurysms 8%; pericallosal artery 6% and internal carotid artery (ICA) tip 5%. The mortality was 7.9%, and such cases presenting with Hunt Hess graduation 3 and 4. The permanent morbidity was 4.5%, cases with Hunt Hess graduation 3 and 4. Perioperative rupture occurred in 17% of the cases, only in previous ruptured aneurysms. There was no clinical evidence of rebleeding during the follow-up period of the series. Conclusions: The microsurgical clipping of cerebral aneurysms of the anterior circulation is a safe and curative treatment for most of such lesions. At present, studies suggest evidences of superior results of surgery compared to the endovascular techniques in the rates of total occlusion of the aneurysms, lesser rates of rebleeding of the treated cases. The results of the present series are similar to the rates of the most relevant literature.

Efficacy and safety of flow diverters in posterior circulation aneurysms and comparison with their efficacy in anterior circulation aneurysms: A systematic review and meta-analysis

2021 ◽  
pp. 159101992110030
Author(s):  
Mohamed Abdel-Tawab ◽  
Ahmed K Abdeltawab ◽  
Mohamed Abdelmonem ◽  
Mahmoud A Moubark ◽  
Mohamed AH Taha ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Cerebral Aneurysms ◽  
Flow Diverter ◽  
Posterior Circulation ◽  
Efficacy And Safety ◽  
Analysis Model ◽  
Anterior Circulation ◽  
Mortality And Morbidity ◽  
Posterior Circulation Aneurysms ◽  
Anterior Circulation Aneurysms

Purpose We aimed to assess the efficacy and safety of flow-diverter stents (FDs) in the management of posterior circulation cerebral aneurysms and compare FD efficacy between anterior and posterior circulation aneurysms. Methods We searched the PubMed, Scopus, Cochrane, and Web of Science databases for relevant studies through March 2020. Studies assessing FDs for posterior circulation aneurysms that included ≥20 treated aneurysms were included. Moreover, the studies compared FD efficacy between anterior and posterior circulation aneurysms were included. Data regarding angiographic aneurysmal occlusion, procedural complications, mortality, and morbidity were extracted and pooled in a random-effects meta-analysis model. Results Fourteen studies with a total of 659 patients and 676 posterior circulation aneurysms were included. The pooled rate of aneurysmal occlusion at long-term angiographic follow-up was 78% [95% confidence interval (CI), 71–85]. The pooled rates of intraparenchymal hemorrhage, ischemia, and procedure-related mortality and neurological morbidity were 2%, 8%, 7%, and 6%, respectively. Complete occlusion occurred in 82.4% of the posterior circulation aneurysm subgroup and 77.5% of the anterior circulation aneurysm subgroup. The difference was not significant (relative risk 1.01; 95% CI, 0.86–1.19; p = 0.91). Regression analysis showed that elderly patients and females had higher morbidity. Conclusion Posterior circulation aneurysms can be effectively treated with FDs with comparable occlusion rates to those in anterior circulation aneurysms. However, periprocedural complications are not negligible.

scholarly journals Application of the Endoscopic Micro-Inspection Tool QEVO® in the Surgical Treatment of Anterior Circulation Aneurysms—A Technical Note and Case Series

2020 ◽  
Vol 7 ◽  
Author(s):  
Karl-Michael Schebesch ◽  
Christian Doenitz ◽  
Amer Haj ◽  
Julius Höhne ◽  
Nils Ole Schmidt
Keyword(s):  
Case Series ◽  
Cerebral Aneurysms ◽  
Technical Note ◽  
The Novel ◽  
Digital Subtraction ◽  
Aneurysm Surgery ◽  
Anterior Circulation ◽  
Unruptured Cerebral Aneurysms ◽  
Cerebral Ischemic ◽  
Anterior Circulation Aneurysms

Introduction: The application of neuro-endoscopes in cerebral aneurysm surgery may help to avoid unintended aneurysm remnants and the accidental clipping of perforating arteries and aid the detection of blood collecting in the subdural spaces. Here, we present our experience with the novel endoscopic micro-inspection tool QEVO® (Carl Zeiss Meditec, Germany) in aneurysm surgery.Materials and Equipment: In all patients the surgical microscope KINEVO® (Carl Zeiss Meditec, Germany) and the Microinspection tool QEVO® were applied.Methods: The case series comprises 22 unruptured cerebral aneurysms of the anterior circulation. All aneurysms were treated surgically. All patients routinely underwent computed tomography and digital subtraction angiography within 10 days after surgery.Results: No aneurysm remnants, cerebral ischemic deficits, or subdural hematomas were detected.Discussion: In this technical note, we discuss the benefits and limitations of the QEVO® tool and illustrate the major paradigms by means of intraoperative photographs.

scholarly journals Comparison of Efficacy of Intraoperative Indocyanine Green Videoangiography in Clipping of Anterior Circulation Aneurysms with Postoperative Digital Subtraction Angiography

2017 ◽  
Vol 08 (03) ◽  
pp. 342-345 ◽  
Author(s):  
Vikas Kumar ◽  
Anita Jagetia ◽  
Daljit Singh ◽  
Arvind Kumar Srivastava ◽  
Monica Sehgal Tandon
Keyword(s):  
Indocyanine Green ◽  
Digital Subtraction Angiography ◽  
Cerebral Aneurysms ◽  
Postoperative Outcome ◽  
Cost Effective ◽  
Digital Subtraction ◽  
Anterior Circulation ◽  
Indocyanine Green Videoangiography ◽  
Aneurysm Neck ◽  
Anterior Circulation Aneurysms

ABSTRACT Introduction: The aim of this study is to assess the efficacy of intraoperative indocyanine green videoangiography (ICG-VA) using postoperative digital subtraction angiography (DSA) in clipped anterior circulation aneurysms. Materials and Methods: A prospective study was conducted for 1 year which included thirty patients of anterior circulation aneurysm treated by clipping of aneurysm. Intraoperative ICG-VA was performed on all the patients. Postoperative DSA was performed to assess the efficacy of ICG-VA. Results: Intraoperative ICG-VA revealed the occlusion of aneurysm in all the thirty patients. Postoperative DSA revealed aneurysm neck remnant in two patients and demonstrated no branch occlusion. Conclusions: Intraoperative ICG-VA is useful in assessing the completeness of clipping of cerebral aneurysms and ensures patency of branch vessels, thus providing a better postoperative outcome. It replaces the need for invasive postoperative angiographic imaging in a selected group of patients and is also cost effective.

scholarly journals Selective cerebral revascularization as an adjunct in the treatment of giant anterior circulation aneurysms

2003 ◽  
Vol 14 (3) ◽  
pp. 1-8 ◽  
Author(s):  
Brian A. O'Shaughnessy ◽  
Sean A. Salehi ◽  
Stefan A. Mindea ◽  
H. Hunt Batjer
Keyword(s):  
Cerebral Aneurysms ◽  
Preoperative Assessment ◽  
Cerebral Revascularization ◽  
Definitive Treatment ◽  
Parent Artery ◽  
Revascularization Procedure ◽  
Anterior Circulation ◽  
Cerebrovascular Reserve ◽  
Temporary Occlusion ◽  
Anterior Circulation Aneurysms

Cerebral revascularization, an indispensable component of neurovascular surgery, has been performed in the treatment of cranial base tumors, complex cerebral aneurysms, and occlusive cerebrovascular disease. The goal of a revascularization procedure is to augment blood flow distally. It can therefore be used as an adjunctive measure in the treatment of complex neurosurgical disease processes that require parent artery sacrifice for definitive treatment. In the treatment of giant anterior circulation aneurysms, for instance, a cerebral revascularization procedure may be considered in patients in whom the collateral circulation is marginal and in whom lesions may be treated either using a Hunterian-based strategy or clip-assisted reconstruction requiring a prolonged period of temporary occlusion. To date, there is no entirely effective method known to produce long-term tolerance to carotid artery (CA) sacrifice and, largely for that reason, some neurovascular surgeons advocate universal revascularization. The authors of this report, however, prefer to perform revascularization only in the limited subset of patients in whom preoperative assessment has revealed risk factors for cerebral ischemia due to hypoperfusion. In this paper, the authors introduce their protocol for assessing cerebrovascular reserve capacity, indications for cerebral revascularization in the treatment of complex anterior circulation aneurysms, and discuss their rationale for choosing to practice selective, rather than universal, revascularization.

scholarly journals A Systematic Review on Mucormycosis in Corona Patients and its Treatment in India

2021 ◽  
Vol 53 (03) ◽  
pp. 236-243
Author(s):  
S Rehan Ahmad ◽  
Keyword(s):  
Fungal Infections ◽  
Secondary Infection ◽  
Management Strategies ◽  
Organ Transplant ◽  
Treatment Strategies ◽  
Current Status ◽  
Monitoring Process ◽  
Associated Risk Factors ◽  
Opportunistic Pathogenic ◽  
Almost All

Several cases of mucormycosis infection are being reported from almost all states of India currently. Mucormycosis infection is rare but fatal.It is strongly associated with COVID- 19 as a secondary infection and increases the severity of COVID-19 infection. Fungi under Mucoralesorder are responsible for mucormycosis infection condition, especially people with a weak immune system and under steroid-based medication and antibiotic treatment are more vulnerable. COVID- 19 infected patients with associated risk factors like diabetes mellitus, neutropenia, diabetic ketoacidosis, organ transplant, cancer, AIDS, weak immunity, autoimmune disorders are more prone tosecondary opportunistic pathogenic infections. Special care and continuous monitoring process should be initiated as early as possible to prevent any kind of secondary fungal infections during COVID-19 infection. Though preventive strategies like antifungal therapy,and surgical debridement are present yetthemortality rate is very high in mucormycosis infection. Moreover, this current study is a brief summary of the current status, pathogenesis, management strategies, and latest guidelines for mucormycosis infection during the pandemic of coronavirusdisease 2019. Several treatment strategies like drugs, surgery, and other proper methods in hospital setups are also mentioned elaborately in this study. Appropriate doses, administration route and duration as well as reported cases of mucormycosis infection from different parts of India are also clearly documented here.

Comparative Anatomical Analysis between Minipterional and Supraorbital Approaches in the Treatment of Anterior Circulation Aneurysms

2020 ◽  
Author(s):  
Rafael Martinez-Perez ◽  
Thiago Albonette-Felicio ◽  
Giuliano Silveira-Bertazzo ◽  
Luis Requena ◽  
Ruichun Li ◽  
...  
Keyword(s):  
Anterior Circulation ◽  
Anatomical Analysis ◽  
Anterior Circulation Aneurysms
Sign in / Sign up

Export Citation Format

Share Document