scholarly journals Relationship Between Prepregnancy and Early Pregnancy Uterine Blood Flow and Resistance Index

2009 ◽  
Vol 16 (11) ◽  
pp. 1091-1096 ◽  
Author(s):  
Sarah A. Hale ◽  
Adrienne Schonberg ◽  
Gary J. Badger ◽  
Ira M. Bernstein
Keyword(s):  
Blood Flow ◽  
Early Pregnancy ◽  
Resistance Index ◽  
Uterine Blood Flow

Increasing Maternal Blood Pressure with Ephedrine Increases Uterine Artery Blood Flow Velocity during Uterine Contraction

2002 ◽  
Vol 96 (3) ◽  
pp. 612-616 ◽  
Author(s):  
Laurent Ducros ◽  
Philippe Bonnin ◽  
Bernard P. Cholley ◽  
Eric Vicaut ◽  
Moncef Benayed ◽  
...  
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Uterine Artery ◽  
Uterine Contraction ◽  
Perfusion Pressure ◽  
Resistance Index ◽  
Hemodynamic Parameters ◽  
Uterine Blood Flow ◽  
Uterine Contractions ◽  
Uterine Perfusion

Background During labor, ephedrine is widely used to prevent or to treat maternal arterial hypotension and restore uterine perfusion pressure to avoid intrapartum fetal asphyxia. However, the effects of ephedrine on uterine blood flow have not been studied during uterine contractions. The purpose of the study was to assess the effects of ephedrine on uterine artery velocities and resistance index using the Doppler technique during the active phase of labor. Methods Ten normotensive, healthy parturients with uncomplicated pregnancies at term received intravenous ephedrine during labor to increase mean arterial pressure up to a maximum of 20% above their baseline pressure. Peak systolic and end-diastolic Doppler flow velocities and resistance indices were measured in the uterine artery before and immediately after administration of bolus intravenous ephedrine and after ephedrine washout. Umbilical and fetal middle cerebral arterial resistance indices and fetal heart rate were also calculated. Results After ephedrine administration, mean arterial pressure increased by 17 +/- 4%. End-diastolic flow velocity in the uterine artery at peak amplitude of uterine contraction was restored to 74% of the value observed in the absence of contraction. The systolic velocity was totally restored, and the uterine resistance index was significantly decreased, compared with the values in the absence of contraction. Between uterine contractions, ephedrine induced similar but less marked effects. Fetal hemodynamic parameters were not altered by ephedrine administration. Conclusions Bolus administration of intravenous ephedrine reversed the dramatic decrease in diastolic uteroplacental blood flow velocity and the increase in resistance index during uterine contraction, without altering fetal hemodynamic parameters. This suggests that the increase in uterine perfusion pressure during labor could in part restore uterine blood flow to the placenta during uterine contraction.

P04.07: A prospective study of the effect of mifepristone on the uterine blood flow during early pregnancy

2004 ◽  
Vol 24 (3) ◽  
pp. 289-289
Author(s):  
C. F. Li ◽  
C. C. W. Chan ◽  
W. Cheung ◽  
W. W. K. So ◽  
P. C. Ho
Keyword(s):  
Blood Flow ◽  
Prospective Study ◽  
Early Pregnancy ◽  
Uterine Blood Flow ◽  
A Prospective Study

Elevated NK cell level and autoimmunity synergistically decrease uterine blood flow during early pregnancy

2012 ◽  
Vol 98 (3) ◽  
pp. S27
Author(s):  
H. Yi ◽  
J.Y. Kwak-Kim ◽  
H. Koo ◽  
M. Choi ◽  
C. Park ◽  
...  
Keyword(s):  
Blood Flow ◽  
Early Pregnancy ◽  
Nk Cell ◽  
Uterine Blood Flow ◽  
Cell Level

Uterine blood flow in relation to endogenous hormones during estrous cycle and early pregnancy

1983 ◽  
Vol 245 (6) ◽  
pp. R843-R849 ◽  
Author(s):  
H. Roman-Ponce ◽  
D. Caton ◽  
W. W. Thatcher ◽  
R. Lehrer
Keyword(s):  
Blood Flow ◽  
Estrous Cycle ◽  
Early Pregnancy ◽  
Significant Relationship ◽  
Peripheral Blood ◽  
Endogenous Hormones ◽  
Uterine Blood Flow ◽  
Data Support ◽  
The Relationship

To evaluate the extent to which endogenous hormones in peripheral blood can account for uterine blood flow (UBF), rates of blood flow and concentrations of estrone (E1), estradiol (E2), and progesterone (P4) were measured simultaneously in four sheep during the estrous cycle and the first 3 wk of pregnancy. During the estrous cycle, UBF was inversely related to the concentration of P4 (P less than 0.01) and directly related to (E1 + E2)/P4 (P less than 0.01). There was no animal in which UBF was related to estrogen alone. No statistically significant relationship between endogenous hormones and UBF was detected in any ewe during the first 3 wk of pregnancy. Data support the idea that UBF varies during the estrous cycle in relation to peripheral concentrations of P4 and (E1 + E2)/P4 but leaves open the nature of the relationship in early pregnancy.

BLOOD FLOW IN THE REPRODUCTIVE ORGANS OF THE MOUSE AFTER HYPOPHYSECTOMY, AFTER GONADOTROPHIN TREATMENT, DURING THE OESTROUS CYCLE AND DURING EARLY PREGNANCY

1969 ◽  
Vol 44 (4) ◽  
pp. 523-536 ◽  
Author(s):  
B. M. BINDON
Keyword(s):  
Blood Flow ◽  
Early Pregnancy ◽  
Reproductive Organs ◽  
Oestrous Cycle ◽  
Unit Weight ◽  
Organ Blood Flow ◽  
Uterine Blood Flow ◽  
Low Levels ◽  
The Brain ◽  
In Pregnancy

SUMMARY The indicator fractionation technique was examined and found to be of value in the measurement of organ blood flow in the anaesthetized female mouse with [131I]iodoantipyrine as the indicator substance. Blood flow per unit weight of the brain and ovary was shown to decline rapidly after hypophysectomy. A single injection of pregnant mare serum gonadotrophin (PMS), given 4 days after hypophysectomy, restored the blood flow of these organs to normal levels. Uterine blood flow was unaffected by hypophysectomy, and was significantly increased by PMS injection. Significant changes in brain, ovarian and uterine blood flow were observed during the oestrous cycle, early pregnancy and in mice induced to ovulate by injections of gonadotrophin. There was a tendency for brain and ovarian blood flow to decline before ovulation. By contrast, significant transient increases in blood flow to the brain and ovary were observed on day 3 of pregnancy. It is thought that these changes are related to the mechanisms which initiate implantation. Uterine blood flow was lowest in mated and unmated mice on the day of oestrus and rose to peak levels 2 days later. In pregnancy, however, peak uterine blood flow was recorded between days 3 and 4 and was higher than at any stage in the oestrous cycle. Although it tended to fall after day 3, uterine blood flow in pregnancy did not decline again to low levels as it did in the oestrous cycle. The possible physiological significance of the results is discussed, and the limitations to their interpretation are considered.

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