Treatment patterns in women seeking care for endometriosis at an endometriosis center

2021 ◽  
pp. 228402652110456
Author(s):  
Katharine E Linder ◽  
Tatnai L Burnett ◽  
Chia-Sui Weng ◽  
Zaraq Khan ◽  
Kristin Mara ◽  
...  
Keyword(s):  
Drug Use ◽  
Pelvic Pain ◽  
Significant Relationship ◽  
Illicit Drug ◽  
Pelvic Floor Dysfunction ◽  
Illicit Drug Use ◽  
Surgical Excision ◽  
Hormonal Contraceptives ◽  
Opioid Use ◽  
Prior Surgery

Objective: To determine the clinical characteristics and prior medical and surgical treatments in women undergoing surgical excision of endometriosis for pelvic pain at a single institution. Methods: In this retrospective cohort study we identified 140 women with pathology-proven endometriosis who completed a preoperative standardized pain form and underwent surgery at an endometriosis center. Women were stratified into three groups for analysis: no prior surgery, 1 prior surgery, and 2+ prior surgeries. Results: The most common treatments used prior to seeking care were hormonal contraceptives (51.6%) and surgery (46.1%). More than half of women were diagnosed with pelvic floor dysfunction at time of presentation or prior to consultation. There was a significant relationship between an increasing number of surgeries (none vs 1 vs 2+) and gonadotropin-releasing hormone (GnRH) agonist use (19.0% vs 27.5% vs 56.0%, p = 0.003). Though not significant, a trend was noted between increasing surgeries and opioid use (20.6% vs 30.0% vs 40.0%, p = 0.17). There was a statistically significant relationship between multiple surgeries and illicit drug use ( p < 0.001). Conclusion: Patients with pelvic pain and endometriosis who have undergone multiple surgeries are more likely to have used GnRH agonists and report illicit drug use prior to presenting to specialized care.

Non‐medical prescription opioid use and in‐hospital illicit drug use among people who use drugs

2021 ◽  
Author(s):  
Gurjit S. Parmar ◽  
Kanna Hayashi ◽  
Seonaid Nolan ◽  
M.‐J. Milloy ◽  
Kora DeBeck ◽  
...  
Keyword(s):  
Drug Use ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Prescription Opioid ◽  
People Who Use Drugs ◽  
Opioid Use ◽  
Medical Prescription ◽  
Prescription Opioid Use

Opioid Use Disorder and Associated Infectious Disease: The Role of the Laboratory in Addressing Health Disparities

2020 ◽  
Author(s):  
Christopher W Farnsworth ◽  
Matthew Lloyd ◽  
Sophonie Jean
Keyword(s):  
Infectious Disease ◽  
Health Disparities ◽  
Drug Use ◽  
Laboratory Testing ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Opioid Use Disorder ◽  
Morbidity And Mortality ◽  
Opioid Use

Abstract Background Opioid use disorder, defined as a pattern of problematic opioid use leading to clinically significant impairment, has resulted in considerable morbidity and mortality throughout the world. This is due, at least in part, to the marginalized status of patients with opioid use disorder, limiting their access to appropriate laboratory testing, diagnosis, and treatment. Infections have long been associated with illicit drug use and contribute considerably to morbidity and mortality. However, barriers to testing and negative stigmas associated with opioid use disorder present unique challenges to infectious disease testing in this patient population. Content This review addresses the associations between opioid use disorder and infectious organisms, highlighting the health disparities encountered by patients with opioid use disorder, and the important role of laboratory testing for diagnosing and managing these patients. Summary Infections are among the most frequent and adverse complications among patients with opioid use disorder. As a result of health disparities and systemic biases, patients that misuse opioids are less likely to receive laboratory testing and treatment. However, laboratories play a crucial in identifying patients that use drugs illicitly and infections associated with illicit drug use.

Prevalence of Self-Reported Prescription Opioid Use and Illicit Drug Use among U.S. Adults

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ja K. Gu ◽  
Penelope Allison ◽  
Alexis Grimes Trotter ◽  
Luenda E. Charles ◽  
Claudia C. Ma ◽  
...  
Keyword(s):  
Drug Use ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Prescription Opioid Use

scholarly journals Concurrent drug use among methadone maintenance patients in mountainous areas in northern Vietnam

BMJ Open ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. e015875 ◽  
Author(s):  
Bach Xuan Tran ◽  
Victoria L Boggiano ◽  
Huong Lan Thi Nguyen ◽  
Long Hoang Nguyen ◽  
Hung Van Nguyen ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Drug Use ◽  
Illicit Drug ◽  
Methadone Maintenance ◽  
Illicit Drug Use ◽  
Secondary Outcome ◽  
Mountainous Area ◽  
Mountainous Areas ◽  
Opioid Use ◽  
Factors Associated

ObjectivesWith the rise in methadone maintenance therapy (MMT) for drug users in Vietnam, there has been growing interest in understanding if and how often MMT patients engage in concurrent illicit drug use while on methadone therapy in various settings. This study examined factors associated with concurrent opioid use among patients on MMT in a mountainous area in Vietnam.SettingOne urban and one rural MMT clinics in Tuyen Quang province.ParticipantsSurvey participants consisted of patients who were taking MMT at the selected study sites. A convenience sampling approach was used to recruit the participants.Primary and secondary outcome measuresParticipants were asked a series of questions about their socioeconomic status, current alcohol and tobacco use, health problems (measured by the EuroQol-Five Dimension-Five Level instrument), psychological distress (measured by Kessler score), and factors associated with current and/or previous drug use. Regression models were used to determine factors associated with concurrent drug use among MMT patients.ResultsAmong the 241 male MMT patients included in the study, 13.4% reported concurrent opioid use. On average, the longer patients had been enrolled in MMT, the less likely they were to concurrently use drugs. Conversely, patients with higher levels of psychological distress were more likely to engage in concurrent drug use while on MMT.ConclusionLonger duration of MMT was significantly correlated with reduced illicit drug use among participants. Higher levels of psychological distress were associated with increased use of illicit drugs among MMT patients. Regardless of distance, long-term MMT is still effective and should be expanded in mountainous areas.

scholarly journals The prospective association between illicit drug use and nonprescription opioid use among vulnerable adolescents

2021 ◽  
Vol 143 ◽  
pp. 106383
Author(s):  
James Russell Pike ◽  
Javad Salehi Fadardi ◽  
Alan W. Stacy ◽  
Bin Xie
Keyword(s):  
Drug Use ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Opioid Use ◽  
Prospective Association

scholarly journals Urine Screening for Opiod and Illicit Drugs in the Total Joint Arthroplasty Population

2020 ◽  
Vol 13 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Matthew Vopat ◽  
William Messamore ◽  
Jesse Trent ◽  
Ken Schmanke ◽  
Rosey Zackula ◽  
...  
Keyword(s):  
Drug Use ◽  
Illicit Drugs ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Joint Arthroplasty ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Number Of Patients ◽  
Patient Reported ◽  
History Of

Introduction. Recent studies have shown an increase in post-operative orthopaedic complications associated with pre-operative opioid use. It is, therefore, important to know if patients use opioids before scheduled surgery. The purpose of this study was to determine if urine drug screening (UDS) is an effective screening tool for detecting opioid and illicit drug use prior to joint arthroplasty (JA) procedures. Methods. This retrospective chart review was performed with IRB approval on 166 out of 172 consecutive patients in a community-based practice. All the patients had a pre-operative UDS prior to primary or revision JA by a fellowship trained orthopaedic surgeon between March 2016 and April 2017. Patient demographics documented opioid and illicit drug use, co-morbid diagnosis, and UDS results were collected from clinical charts. Statistical analysis was conducted using Pearson Chi-square, Fisher’s exact, McNemar test, and t-tests with IBM SPSS Statistics, ver. 23. Significant differences were p < 0.05. Results. Sixty-four of 166 patients (38.6%) tested positive for opioids. Among them, 55.0% (35/64) had no history of prescription opioid use. Significant differences were observed when comparing the test results of the UDS with the patient reported history of prescribed opioids (p = 0.001). Conclusion. With a significant number of patients testing positive for opioids without evidence of a previous prescription, UDS may be beneficial for initial risk assessment for patients undergoing JA procedures.

Jurisdictional differences in opioid use, other licit and illicit drug use, and harms associated with substance use among people who tamper with pharmaceutical opioids

2015 ◽  
Vol 34 (6) ◽  
pp. 611-622 ◽  
Author(s):  
Amy Peacock ◽  
Raimondo Bruno ◽  
Elena Cama ◽  
Ivana Kihas ◽  
Briony Larance ◽  
...  
Keyword(s):  
Substance Use ◽  
Drug Use ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Opioid Use

Storage, disposal, and utilization of opioids among cancer outpatients.

2013 ◽  
Vol 31 (31_suppl) ◽  
pp. 222-222
Author(s):  
Akhila Sunkepally Reddy ◽  
Maxine Grace Jaucian De La Cruz ◽  
Eden Mae Rodriguez ◽  
Jessica Thames ◽  
Jimin Wu ◽  
...  
Keyword(s):  
Drug Use ◽  
Adult Children ◽  
Illicit Drug ◽  
Care Center ◽  
Illicit Drug Use ◽  
Patient Characteristics ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Never Married ◽  
History Of

222 Background: Prescription opioid abuse is an epidemic in the US. Of the abusers, 75% obtain the opioid from a friend or relative, which may be related to improper opioid storage and disposal practices. Our aim was to determine patients’ practices of opioid use, storage, and disposal. Methods: We surveyed 300 cancer outpatients presenting to our Supportive Care Center who were receiving opioids for at least 1 month and collected information regarding opioid use, storage, and disposal along with patient characteristics and scores on Cut-down, Annoyed, Guilty, Eye-opener (CAGE) questionnaire for alcoholism. Sharing or losing their opioids was defined as an unsafe use. Results: The median age of the patients was 57 years; 53% were female, 72% were white, and 63% were married. Most (89%) had advanced cancer, and lung cancer was the most common (22%). CAGE was positive in 19%, 9% had history of illicit drug use, and 36% lived with adult/young adult children. Of the 300 respondents, 19% stored opioids in the open, 69% kept opioids hidden but unlocked, and 9% locked their opioids. Patients with history of CAGE positivity (P=.007), illicit drug use (.0002), smoking (P=.03), and those living with adult children (P=.004) were more likely to keep their opioids locked. 66% were unaware of proper opioid disposal methods. 46% had unused opioids at home. 53% did not routinely dispose opioids, of whom 44% saved them for future use. 26% indulged in unsafe use by sharing (9%) or losing (17%) their opioids, and 44% informed their family and friends that they were on pain medications. 39% were unaware that their opioid could be fatal when taken by others. Compared with married patients, those who were never married [OR=2.92; 95% CI 1.48-5.77], separated [OR=11.38; 1.52-112.5], or divorced [OR=1.27; 0.55-2.91] had higher odds of unsafe use (P=.006). CAGE positivity (40% vs. 21%, P=.003) and illicit drug use (42% vs. 23%, P=.031) were also significant predictors of unsafe use. Conclusions: An alarming proportion of patients improperly and unsafely use, store, and dispose of opioids. Patient education by physicians/pharmacists and creation of more drug take back programs may reduce availability of prescription opioids for potential abuse. More research is needed in this area.

scholarly journals Outcomes in patients with acute myocardial infarction and a history of illicit drug use: a nationwide analysis

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Genet ◽  
I Ma ◽  
A Bisson ◽  
A Bodin ◽  
J Herbert ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Drug Use ◽  
Illicit Drug ◽  
Univariate Analysis ◽  
Illicit Drug Use ◽  
Opioid Use ◽  
Risk Of Death ◽  
History Of ◽  
One Year

Abstract Background Several reports suggest that illicit drug use may be a major cause of acute myocardial infarction (AMI) independently of smoking habits, and associated with a poorer prognosis. Purpose We sought to determine the frequency of history of illicit drug use in an AMI population and its impact on short- and mid-term prognosis. Methods Based on the administrative hospital-discharge database, we collected information for all patients treated with AMI between 2010 and 2018 in France. We identified patients with history of illicit drug use and the adverse outcomes were investigated during follow-up. Results Among 797,212 patients with ST-segment elevation myocardial infarction (STEMI) or non-STEMI (mean age 69 years, 66% male), 3827 patients (0.5%) had a known history of illicit drug use (cannabis, cocaine or opioid). Patients with illicit drug use were younger and had less comorbidities. They presented more frequently with STEMI and anterior localization compared to those with no history of illicit drug use. In univariate analysis, patients with illicit drug use had lower short-term mortality rates compared to those without history of illicit drug use: 4.9% vs 10.1% at one month (p&lt;0.0001), respectively. However, this might be attributed to a younger age at the time of presentation. Using logistic multivariable analysis with adjustment on age, gender, other cardiovascular and non-cardiovascular comorbidities, type and localisation of MI and procedures of revascularization, history of illicit drug use was associated with a non-significant higher risk of death at one year (adjusted odds ratio OR 1.12 95% CI 0.98–1.29). This trend was supported by a significantly higher risk of death at one year in patients with a history of opioid use (OR 1.27 95% CI 1.04–1.29, p=0.01). Conclusion In a large and systematic nationwide analysis of patients with AMI, history of illicit drug use was associated with a non-significant higher overall odds of mortality, which was significant among those with opioid use. Funding Acknowledgement Type of funding source: None

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