scholarly journals Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume in patients with idiopathic epiretinal membrane

2021 ◽  
Vol 13 ◽  
pp. 251584142110105
Author(s):  
Gokhan Demir ◽  
Husna Topcu ◽  
Semih Cakmak ◽  
Funda Ebru Aksoy ◽  
Mehmet Emin Sucu ◽  
...  
Keyword(s):  
Mean Platelet Volume ◽  
Epiretinal Membrane ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
Platelet Volume ◽  
Platelet To Lymphocyte Ratio ◽  
Idiopathic Epiretinal Membrane ◽  
Lymphocyte Ratio ◽  
Control Subjects ◽  
The Mean

Purpose: To assess the role of inflammation in the pathogenesis of idiopathic epiretinal membrane (iERM) using the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) as indicators of inflammation and to compare these parameter levels between iERM and control subjects. Methods: We retrospectively analyzed the medical records of 36 patients who underwent vitrectomy-ERM peeling and 39 patients who had cataract surgery. We obtained blood samples from all individuals who participated in the study to investigate these parameters. Results: Seventy-five subjects were included in this study: 36 in the iERM group and 39 in the control group. The mean neutrophil and MPV levels were significantly higher in iERM subjects than in control subjects. The mean lymphocyte level was lower in the iERM group. The mean NLR, PLR, and MPV levels were higher in iERM subjects than in control subjects. Conclusion: The higher NLR, PLR, and MPV levels found in patients with iERM may indicate that subclinical systemic inflammation may associate with iERM.

Investigation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus

2018 ◽  
Vol 132 (2) ◽  
pp. 129-132 ◽  
Author(s):  
B Ulusoy ◽  
K Bozdemir ◽  
M Akyol ◽  
H İ Mişe ◽  
A Kutluhan ◽  
...  
Keyword(s):  
Mean Platelet Volume ◽  
Statistical Significance ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Platelet To Lymphocyte Ratio ◽  
Distribution Width ◽  
Significance Level ◽  
Lymphocyte Ratio

AbstractObjective:This study aimed to evaluate patients with tinnitus in terms of mean platelet volume and platelet distribution width, and to explore neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, recently reported in the literature as being possible inflammation markers.Methods:This study comprised 64 tinnitus patients and 64 age-matched healthy controls. Statistical significance level was accepted as p < 0.05.Results:Mean platelet volume (t = 3.245, p = 0.002) and platelet distribution width (Z = 3.945, p < 0.001) were significantly higher in the patient group than the control group.Conclusion:The results suggest that a prothrombotic condition might play a role in the pathophysiology of tinnitus.

scholarly journals Preoperative Neutrophil to Lymphocyte Ratio, Platelet to Lymphocyte Ratio, and Mean Platelet Volume as Predictors of 1-Year Mortality in Patients Undergoing an Open Repair of Abdominal Aortic Aneurysms: A Retrospective Study

2021 ◽  
Vol 10 (22) ◽  
pp. 5410
Author(s):  
Da Eun Ko ◽  
Hei Jin Yoon ◽  
Sang Beom Nam ◽  
Suk Won Song ◽  
Gisong Lee ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Subgroup Analysis ◽  
Mean Platelet Volume ◽  
Odds Ratio ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet Volume ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Survivor Group ◽  
Abdominal Aortic

Objectives: To investigate if preoperative neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), or mean platelet volume (MPV) could be used to predict 1-year mortality in patients undergoing open abdominal aortic aneurysm (AAA) repair. Methods: We retrospectively reviewed 382 patients who underwent open AAA repair between January 2008 and July 2019. We divided the patients into two groups based on 1-year mortality and compared the preoperative NLR, PLR, and MPV. The patients were then classified into tertiles based on their preoperative NLR (first tertile: < 2.41 (n = 111); second tertile: 2.41 ≤ NLR ≤6.07 (n = 111); and third tertile: > 6.07 (n = 112)). We compared the incidence of mortality and morbidity across the aforementioned tertiles. We performed a stepwise logistic regression analysis to evaluate the predictors for mortality. An additional subgroup analysis was performed by dividing the cases into non-ruptured and ruptured cases. Results: The preoperative NLR was significantly higher in the non-survivor group than in the survivor group (10.53 ± 7.60 vs. 5.76 ± 6.44, respectively, p = 0.003). The PLR and MPV were similar between the groups (145.35 ± 91.11 vs. 154.20 ± 113.19, p = 0.626, 9.38 ± 1.20 vs. 9.11 ± 1.39, p = 0.267, respectively). The incidence of 1-year mortality was 2.7%, 9.0%, and 14.3% in the first, second, and third NLR tertiles, respectively (p = 0.009). Higher NLR (odds ratio 1.085, 95% confidence interval 1.016–1.159, p = 0.015) and ruptured AAA (odds ratio 2.706, 95% confidence interval 1.097–6.673, p = 0.031) were the independent predictors of 1-year mortality in all patients. Moreover, the preoperative NLR was significantly higher in the ruptured AAA than in the non-ruptured AAA group (11.17 ± 7.90 vs. 4.10 ± 4.75, p < 0.001). In subgroup analysis, preoperative NLR (odds ratio 1.144, 95% confidence interval 1.031–1.271, p = 0.012) and PLR (odds ratio 0.986, 95% confidence interval 16 0.975–0.998, p = 0.017) was an independent predictor for 1-year mortality in ruptured cases. Conclusions: We demonstrated an independent relationship between the preoperative NLR and 1-year mortality in patients undergoing open AAA repair, besides PLR and MPV. Furthermore, the NLR and PLR had predictive power for 1-year mortality in ruptured cases.

Diagnostic Value of Neutrophil to Lymphocyte Ratio and Mean Platelet Volume on Early Onset Neonatal Sepsis on Term Neonate

2020 ◽  
Author(s):  
Birol Karabulut ◽  
Silem Ozdem Alatas
Keyword(s):  
Neonatal Sepsis ◽  
Predictive Value ◽  
Mean Platelet Volume ◽  
Early Onset ◽  
Area Under The Curve ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
Platelet Volume ◽  
Term Neonates ◽  
Lymphocyte Ratio

AbstractBy setting out from increased neutrophil count, decreased lymphocyte count, and increased mean platelet volume (MPV), which is a result of the effect of inflammation on blood cells, we aimed to investigate whether neutrophil to lymphocyte ratio (NLP) and MPV can be used as an auxiliary parameter for the diagnosis of early-onset neonatal sepsis (EOS). This study was conducted by analyzing term neonates with EOS and physiological jaundice who were admitted to the neonatal intensive care unit of Izmir Katip Celebi University Ataturk Training and Research Hospital. A total of 63 neonate files were examined to include 30 term neonates with EOS, and 77 neonate files were examined to include 30 term neonates with physiological jaundice as a control group. NLR had an area under the curve (AUC) of 0.891 for prediction of EOS. At a cut-off level of 1.42, NLR had a likelihood ratio (LR) of 5.5, sensitivity of 88%, a specificity of 84%, a positive predictive value (PPV) of 84.6%, and a negative predictive value (NPV) of 87.5%. MPV had an AUC of 0.666 for the prediction of EOS and at a cut-off level of 9.3 fL, MPV had an LR of 1.23, sensitivity of 84%, a specificity of 32%, a PPV of 55.2%, and an NPV of 66.6%. In conclusion, this study provides evidence that NLR and MPV can be used in addition to conventional parameters in the diagnosis of EOS.

scholarly journals The role of the mean platelet volume and neutrophil-to-lymphocyte ratio in peritonsillar abscesses

2016 ◽  
Vol 82 (6) ◽  
pp. 662-667 ◽  
Author(s):  
Mehmet Şentürk ◽  
İsa Azgın ◽  
Gültekin Övet ◽  
Necat Alataş ◽  
Betül Ağırgöl ◽  
...  
Keyword(s):  
Mean Platelet Volume ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet Volume ◽  
Lymphocyte Ratio ◽  
The Mean

Platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, and platelet indices in patients with acute deep vein thrombosis

VASA ◽  
2018 ◽  
Vol 47 (2) ◽  
pp. 143-147 ◽  
Author(s):  
Liang Ming ◽  
Zhiyun Jiang ◽  
Junfen Ma ◽  
Qian Wang ◽  
Fan Wu ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Mean Platelet Volume ◽  
Neutrophil To Lymphocyte Ratio ◽  
Platelet Volume ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Vein Thrombosis ◽  
Increased Risk ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

Abstract. Background: Inflammation is associated with an increased risk of thrombotic events and complete blood count (CBC) is an easily measured test. The purpose of this study was to evaluate the value of CBC relative parameters including mean platelet volume (MPV), platelet-to-lymphocyte ratio (PLR), mean platelet volume-to-lymphocyte ratio (MPVLR), and neutrophil-to-lymphocyte ratio (NLR) for patients with acute deep vein thrombosis (DVT). Patients and methods: A total of 115 patients with unprovoked DVT of the lower extremities and 105 controls were recruited in this study. Blood samples were drawn from all participants to obtain the concentrations of CBCs and D-dimers. Results: MPVs (P = 0.044), PLRs (P = 0.005), MPVLRs (P = 0.001), and NLRs (P < 0.0001) were significantly higher in acute DVT patients compared to controls. The MPV was inversely correlated with platelet count (P < 0.0001) and the NLR was positively associated with D-dimers (P = 0.002) and the PLR (P < 0.0001). Notably, on multivariate logistic regression analysis, NLRs and D-dimers were independent risk factors of acute DVT (OR: 1.889, P = 0.024; OR: 1.009, P < 0.0001, respectively). Conclusions: MPV, PLR, MPVLR, and NLR have potential diagnostic values for patients with unprovoked DVT. NLR is an independent risk factor related to DVT.

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