scholarly journals The Relationship of Tumor Necrosis to Red Blood Cell Changes in the Hamster

Blood ◽  
1959 ◽  
Vol 14 (11) ◽  
pp. 1223-1229 ◽  
Author(s):  
JOSEPH D. SHERMAN
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cheek Pouch ◽  
Hamster Cheek Pouch ◽  
Sterile Cell ◽  
Tumor Bearing ◽  
Cell Counts ◽  
Cell Changes ◽  
Relationship Of ◽  
The Relationship

Abstract 1. Sterile, cell-free saline extracts of the necrotic portion of methylcholanthrene-induced hamster sarcoma injected into non-tumor bearing hamsters produced a statistically significant decrease in hemoglobin, hematocrit and red blood cell levels. 2. These changes in hemoglobin, hematocrit and red blood cells are comparable to those observed during sarcoma growth. 3. Sterile, cell-free, extracts of viable sarcoma injected into hamsters failed to produce alterations in the hemoglobin, hematocrit or red blood cell values. 4. The necrosis produced during sarcoma growth in the hamster cheek pouch is concluded to be responsible for alterations in the red blood cell counts, hemoglobin and hematocrit values.

Red blood cell size and the Fåhraeus–Lindqvist effect

2006 ◽  
Vol 84 (3) ◽  
pp. 419-424 ◽  
Author(s):  
G K Snyder ◽  
R D Sears
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Viscosity ◽  
Canis Familiaris ◽  
Relative Viscosity ◽  
Tube Diameter ◽  
Capillary Viscometer ◽  
Glass Capillary ◽  
Relationship Of ◽  
The Relationship

The reason for the large interspecies variation in vertebrate red blood cell (RBC) size is poorly understood. To test the effect of RBC size on blood viscosity, blood samples from two vertebrates, the dog (Canis familiaris L., 1758) and the greater siren (Siren lacertina L., 1766), with extremely different RBC sizes were examined. In this study, we examined whether RBC size altered the relationship of viscosity and viscometer tube diameter, the well-known Fåhraeus–Lindqvist effect (FLE). We used a glass capillary viscometer that incorporates tubes with a diameter narrow enough to evoke the FLE. At similar RBC concentrations, viscosity of suspensions with the larger siren RBCs were greater than the viscosity of suspensions with the smaller dog RBCs. However, the relationship between viscosity and tube diameter is independent of RBC size. The results of this study allow us to conclude that the FLE is not related to RBC size. While packaging hemoglobin in RBCs appears adaptive by reducing blood viscosity through the FLE, RBC size does not contribute to the reductions in tube-relative viscosity.

scholarly journals Subclinical inflammation markers in hyperemesis gravidarum and ketonuria: A case–control study

2019 ◽  
Vol 11 (02) ◽  
pp. 149-153 ◽  
Author(s):  
Ersin çintesun ◽  
Serra Akar ◽  
Ayhan Gul ◽  
Feyza Nur Incesu Çintesun ◽  
Gözde Sahin ◽  
...  
Keyword(s):  
Blood Cell ◽  
Pregnant Women ◽  
Hyperemesis Gravidarum ◽  
Subclinical Inflammation ◽  
Inflammation Markers ◽  
Distribution Width ◽  
Lymphocyte Ratio ◽  
Cell Counts ◽  
Relationship Of ◽  
The Relationship

Abstract INTRODUCTION: Subclinical inflammation markers play a significant role in hyperemesis gravidarum (HEG). Simple hematological markers such as mean platelet volume (MPV), platelet distribution width (PDW), neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW), plateletcrit (PCT), and platelet-to-lymphocyte ratio (PLR) have been shown to reflect inflammatory burden and disease activity in several disorders. Ketonuria is a parameter used in the diagnosis of severe HEG, but its correlation with disease severity remains controversial. The relationship of subclinical inflammation markers with degree of ketonuria has not been examined previously. In this study, we aimed to determine the diagnostic value of these subclinical inflammation markers and the relationship between these markers and grade of ketonuria in patients with HEG. MATERIALS AND METHODS: A total of 94 pregnant women with a diagnosis of HEG and 100 gestational age-matched healthy pregnant women were enrolled in this retrospective study. MPV, PDW, NLR, PLR, PCT, and ketonuria were calculated and analyzed from complete blood cell counts and total urine analyses. RESULTS: Lymphocyte count was significantly higher in the control group (P < 0,001); NLR and PLR values were significantly higher in the HEG group (P < 0,001). Among inflammation markers, RDW increased significantly (P = 0,008) with an increase in ketonuria in patients with HEG. A statistically significant correlation was found between white blood cell (WBC) and NLR, PLR, PCT. A moderate uphill relationship was observed between NLR and WBC and a weak uphill linear relationship was observed between WBC and PLR and between WBC and PCTCONCLUSIONS: PLR and NLR can be considered effective markers to aid in the diagnosis of HEG. No marker was found to correlate with ketonuria grade except RDW, although the relationship of the severity of ketonuria with severity of disease is controversial. RDW increases as the degree of ketonuria increases.

scholarly journals Exploring the relationship of peripheral total bilirubin, red blood cell, and hemoglobin with blood pressure during childhood and adolescence

2018 ◽  
Vol 94 (5) ◽  
pp. 532-538 ◽  
Author(s):  
Xiao-tian Chen ◽  
Song Yang ◽  
Ya-ming Yang ◽  
Hai-long Zhao ◽  
Yan-chun Chen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Total Bilirubin ◽  
Childhood And Adolescence ◽  
Relationship Of ◽  
The Relationship

The relationship between nucleated red blood cell counts and early-onset neonatal seizures

2000 ◽  
Vol 182 (6) ◽  
pp. 1452-1457 ◽  
Author(s):  
Sean C. Blackwell ◽  
Jerrie S. Refuerzo ◽  
Honor M. Wolfe ◽  
Sonia S. Hassan ◽  
Stanley M. Berry ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Early Onset ◽  
Neonatal Seizures ◽  
Cell Counts ◽  
Blood Cell Counts ◽  
The Relationship ◽  
Nucleated Red Blood Cell

The relationship of red blood cell transfusion to intestinal mucosal injury in premature infants

2017 ◽  
Vol 52 (7) ◽  
pp. 1152-1155 ◽  
Author(s):  
Nhan Hyung ◽  
Insiyah Campwala ◽  
Danilo S. Boskovic ◽  
Laurel Slater ◽  
Yayesh Asmerom ◽  
...  
Keyword(s):  
Blood Cell ◽  
Premature Infants ◽  
Red Blood Cell ◽  
Mucosal Injury ◽  
Red Blood Cell Transfusion ◽  
Intestinal Mucosal Injury ◽  
Relationship Of ◽  
The Relationship

scholarly journals Changes of Hematocrit, Hemoglobin, Serum Protein Levels and Red Blood Cell Counts Before and After Stroke

1976 ◽  
Vol 13 (4) ◽  
pp. 207-214
Author(s):  
Hiroshi Yamanouchi ◽  
Hideo Tohgi ◽  
Masakuni Kameyama ◽  
Mototaka Murakami ◽  
Tamotsu Matsuda
Keyword(s):  
Blood Cell ◽  
Serum Protein ◽  
Red Blood Cell ◽  
Protein Levels ◽  
Cell Counts ◽  
Blood Cell Counts ◽  
Before And After

Length-tension relationship of vascular smooth muscle in single arterioles

1989 ◽  
Vol 256 (3) ◽  
pp. H630-H640 ◽  
Author(s):  
M. J. Davis ◽  
R. W. Gore
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Wall Stress ◽  
Physiological Saline ◽  
Intraluminal Pressure ◽  
Cheek Pouch ◽  
Hamster Cheek Pouch ◽  
Longitudinal Response ◽  
Physiological Saline Solution ◽  
Relationship Of

Longitudinal response gradients in the microcirculation may in part be explained in terms of the length-tension relationship of vascular smooth muscle at different points along the vascular tree. To test this hypothesis, four branching orders of arterial vessels (20-80 microns ID) were dissected from the hamster cheek pouch and cannulated with concentric micropipettes. Intraluminal pressure was monitored with a servo-null micropipette, and arteriolar dimensions were measured using a videomicrometer. All arterioles developed spontaneous tone in physiological saline solution. Pressure-diameter curves were recorded for maximally activated vessels and for passive vessels. Maximal active wall tension varied nearly threefold, but maximal active medial wall stress (approximately 4 x 10(6) dyn/cm2) varied only approximately 20% between the different vessel orders. These data support the concept that smooth muscle cells from vessels of different sizes are mechanically similar but do not completely explain the longitudinal response gradients reported in the cheek pouch microcirculation. An analysis of the effect of arteriolar wall buckling suggests that the luminal folds that develop at short vessel radii may broaden the peak of the active stress-length curve and extend the pressure range over which arterioles are most sensitive to physical and chemical stimuli.

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