scholarly journals White blood cells, C-reactive protein and erythrocyte sedimentation rate in pneumococcal pneumonia in children

1997 ◽  
Vol 10 (5) ◽  
pp. 1125-1129 ◽  
Author(s):  
M . Korppi ◽  
T. Heiskanen-Kosma ◽  
M. Leinonen
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Blood Cells ◽  
Pneumococcal Pneumonia ◽  
White Blood Cells ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

The correlation between the concentration of faecal calprotectin and markers of inflammation in children with gastrointestinal disorders

2017 ◽  
Vol 53 (2) ◽  
pp. 91-96
Author(s):  
Katarzyna Lewandowska ◽  
Olga Ciepiela
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Intestinal Inflammation ◽  
White Blood Cells ◽  
Intestinal Lumen ◽  
C Reactive Protein ◽  
Faecal Calprotectin ◽  
Reactive Protein ◽  
Markers Of Inflammation ◽  
Erythrocyte Sedimentation

Introduction: Calprotectin is an acute phase protein that occurs in large amounts in the granules and cytosolic fluid of neutrophils, and in smaller amounts in monocytes and macrophages. In bowel inflammation, increased neutrophil migration from the circulation to the intestinal lumen is observed as a consequence of mucosal damage. This leads to the release of a significant amount of calprotectin by activated leukocytes in intestine, thereby increasing its concentration in the faeces. This allows the non-invasive assessment of intestinal inflammation. Other markers useful in patients with bowel inflammation are erythrocyte sedimentation rate and C-reactive protein. Aim: The aim of the study was to evaluate the correlation between the concentration of faecal calprotectin (FC) and other markers of inflammation, such as C-reactive protein (CRP) and ferritin in serum, erythrocyte sedimentation rate (ESR) and white blood cells (WBC) count and in children with Crohn’s disease and ulcerative colitis. Material and methods: This study is based on a retrospective analysis of laboratory results of 370 children suspected of inflammatory bowel disease (IBD). Pearson’s coefficient was used to assess the correlation between the parameters. Results: There was a positive correlation between concentration of FC and parameters such as CRP (r=0.16; p=0.0345), ESR (r=0.38; p<0.0001) and WBC (r=0.24; p=0.0008) in children with IBD. There was also a negative correlation between concentration of FC and ferritin (r=-0.24; p=0.0089) in children with IBD. Conclusion: In this study, ESR turned out to be more adequate than CRP and WBC in detecting inflammation in patients with IBD.

Diagnostic value of procalcitonin, erythrocyte sedimentation rate (ESR), quantitative C-reactive protein (CRP) and clinical findings associated with osteomyelitis in patients with diabetic foot

2021 ◽  
pp. 1-7
Author(s):  
Zahra Soleimani ◽  
Fatemeh Amighi ◽  
Zarichehr Vakili ◽  
Mansooreh Momen-Heravi ◽  
Seyyed Alireza Moravveji
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Roc Curve ◽  
Diabetic Foot ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Diabetic Patients ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

BACKGROUND: The diagnosis of osteomyelitis is a key step of diabetic foot management. Procalcitonin (PCT) is a novel infection marker. This study aimed to investigate the diagnostic value of procalcitonin and other conventional infection markers and clinical findings in diagnosis of osteomyelitis in diabetic foot patients. METHODS AND MATERIALS: This diagnostic value study was carried out on ninety patients with diabetic infected foot ulcers admitted in Kashan Beheshti Hospital, 2016. After obtaining consent, 10 cc blood sample was taken for measuring serum PCT, CBC, ESR, CRP and FBS. Clinical characteristics of the wounds were noted. Magnetic resonance imaging of the foot was performed in all patients to diagnose osteomyelitis. All statistical analyses were done with the use of SPSS-16. RESULTS: PCT levels were 0.13 ± 0.02 ng/mili patients with osteomyelitis (n= 45) and 0.04 ± 0.02 ng/ml in patients without osteomyelitis (n= 45). PCT, Erythrocyte sedimentation rate and C-reactive protein was found significantly higher in patients with osteomyelitis (p< 0.001). The ROC curve was calculated for PCT. The area under the ROC curve for infection identification was 1 (p< 0.001). The best cut-off value for PCT was 0.085 ng/ml. Sensitivity, specificity, and positive and negative predictive values were 100%, 97.8%,97.8% and 100%, respectively. CONCLUSION: In this group of patients, PCT was useful to discriminate patients with bone infection. Also, Erythrocyte sedimentation rate and C-reactive protein can be used as a marker of osteomyelitis in diabetic patients.

scholarly journals One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis

2017 ◽  
Vol 11 (2) ◽  
pp. 305-313 ◽  
Author(s):  
Tao Zhang ◽  
Lihua Ma ◽  
Xu Lan ◽  
Ping Zhen ◽  
Shiyong Wang ◽  
...  
Keyword(s):  
Internal Fixation ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Bone Grafting ◽  
Oswestry Disability Index ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
One Stage ◽  
Erythrocyte Sedimentation

<sec><title>Study Design</title><p>Retrospective case series.</p></sec><sec><title>Purpose</title><p>To investigate the clinical efficacy and feasibility of one-stage anterolateral debridement, bone grafting, and internal fixation for treating lumbosacral tuberculosis.</p></sec><sec><title>Overview of Literature</title><p>There has been no consensus regarding the optimal means of treating lumbosacral tuberculosis. The one-stage anterolateral extraperitoneal approach for radical debridement, bone grafting, and internal fixation for treating lumbosacral tuberculosis is rare in literature.</p></sec><sec><title>Methods</title><p>Twenty-one patients with lumbosacral tuberculosis were retrospectively analyzed. All patients underwent the surgery of anterolateral debridement after regularly antituberculous drugs therapy. We evaluated the erythrocyte sedimentation rate, C-reactive protein, radiography, computed tomography, magnetic resonance imaging, visual analogue score, and Oswestry disability index before and after surgery.</p></sec><sec><title>Results</title><p>All patients completed a follow-up survey 9–48 months after surgery. All patients' wounds healed well without chronic infection or sinus formation, and all patients with low-back pain reported relief after surgery. All cases had no tuberculosis recurrence. Solid bony fusion was achieved within 6–12 months. At final follow-up, evaluated the erythrocyte sedimentation rate decreased from 38.1±12.5 to 11.3±7.1 mm/hr, C-reactive protein decreased from 6.2±4.2 to 1.6±1.3 mg/dL, the visual analog scale score decreased from 4.6±1.1 to 1.4±1.0, the Oswestry disability index score decreased from 50.2%±11.9% to 13.0%±6.6%, and the lumbosacral angle increased from 20.0°±4.8° to 29.0°±3.9° (<italic>p</italic>&lt;0.05).</p></sec><sec><title>Conclusions</title><p>One-stage anterolateral debridement, bone grafting, and internal instrument fixation for treating lumbosacral tuberculosis is safe and effective.</p></sec>

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