scholarly journals Effects of inspiratory flow waveforms on arterial blood gases and respiratory mechanics after open heart surgery

1997 ◽  
Vol 10 (12) ◽  
pp. 2820-2824 ◽  
Author(s):  
G. Polese ◽  
P. Lubli ◽  
R. Poggi ◽  
A. Luzzani ◽  
J. Milic-Emili ◽  
...  
Keyword(s):  
Heart Surgery ◽  
Respiratory Mechanics ◽  
Open Heart Surgery ◽  
Blood Gases ◽  
Inspiratory Flow ◽  
Open Heart ◽  
Arterial Blood Gases ◽  
Arterial Blood ◽  
Flow Waveforms

scholarly journals Open and Closed Endotracheal Suctioning and Arterial Blood Gas Values: A Single-Blind Crossover Randomized Clinical Trial

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Azam Faraji ◽  
Alireza Khatony ◽  
Gholamreza Moradi ◽  
Alireza Abdi ◽  
Mansour Rezaei
Keyword(s):  
Clinical Trial ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Blood Gases ◽  
Open Heart ◽  
Blood Gas ◽  
Open Technique ◽  
Endotracheal Suctioning ◽  
Arterial Blood Gas ◽  
Arterial Blood

Aim. This study was aimed at comparing the effects of the open and closed suctioning techniques on the arterial blood gas values in patients undergoing open-heart surgery.Methods. In a clinical trial, we recruited 42 patients after open-heart surgery in an educational hospital. Each patient randomly underwent both open and closed suctioning. ABGs, PaO2, SaO2, PaCO2, were analyzed before and one, five, and fifteen minutes after each suctioning episode.Results. At first the pressure of oxygen in arterial blood increased; however, this increase in the open technique was greater than that of the closed system(P<0.001). The pressure of oxygen decreased five and fifteen minutes after both suctioning techniques(P<0.05). The trends of carbon dioxide variations after the open and closed techniques were upward and downward, respectively. Moreover, the decrease in the level of oxygen saturation five and fifteen minutes after the open suctioning was greater than that of the closed suctioning technique(P<0.05).  Conclusion. Arterial blood gas disturbances in the closed suctioning technique were less than those of the open technique. Therefore, to eliminate the unwanted effects of endotracheal suctioning on the arterial blood gases, the closed suctioning technique is recommended.

No potentiation of fentanyl by use of transdermal buprenorphine in patients undergoing fast-track anesthesia for open-heart surgery

2005 ◽  
Vol 1 (3) ◽  
pp. 162 ◽  
Author(s):  
Enno Freye, MD, PhD ◽  
Erhard Hartung, MD ◽  
Joseph Victor Levy, PhD
Keyword(s):  
Fast Track ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Blood Gases ◽  
Control Group ◽  
Open Heart ◽  
Arterial Blood ◽  
Enflurane Anesthesia ◽  
Significant Difference ◽  
Development Of Tolerance

Simultaneous use of opioids with a different pharmacological profile during anesthesia may lead to unexpected prolongation of effects. In addition, long-term use of transdermal buprenorphine may result in a reduced sensitivity to opioid anesthesia. In a prospective study, possible overlap of opioid effects and vigilance was determined in a group of patients (n = 22) using a buprenorphine patch for at least two months for treatment of chronic pain, and undergoing fentanyl-based fast-track enflurane anesthesia for open-heart surgery. The patients using buprenorphine were compared with a control group (n = 21) undergoing similar open-heart procedures with no opioid other than fentanyl on board. Aside from time to extubation, total dose of fentanyl, postoperative blood gases, and vigilance assessment score were used to determine possible overlap of opioid effects and/or development of opioid tolerance in the buprenorphine group compared to the control group. Both groups had similar operation and anesthesia times and comparable doses of fentanyl (0.69 mg ± 0.23 vs. 0.67 mg ± 0.16 SD). There was no significant difference in postoperative arterial blood gases (PaO2 136 ± 48 torr vs. 128 ± 35 torr SD; PCO2 43.3 ± 3.3 torr vs. 41.9 ± 1.2 torr SD), time until extubation (27 ± 22 min vs. 33 ± 24 min), and postanesthetic vigilance and recovery score (6.8 ± 1.0 vs. 7.5 ± 0.8, arbitrary units) between the two groups. Because of adaptive mechanisms and the development of tolerance in patients using buprenorphine, respiratory depression or sedation does not project into the postoperative period. The significant (p < 0.05) lower incidence of nausea and emesis in patients with transdermal buprenorphine owes to the development of tolerance to these opioid-related side effects.

scholarly journals Lung Mechanics in Type L CoVID-19 Pneumonia: A Pseudo-Normal ARDS.

2020 ◽  
Author(s):  
Lorenzo Viola ◽  
Emanuele Russo ◽  
Marco Benni ◽  
Emiliano Gamberini ◽  
Alessandro Circelli ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Respiratory System ◽  
Respiratory Mechanics ◽  
Blood Gases ◽  
Lung Mechanics ◽  
Prone Positioning ◽  
Arterial Blood Gases ◽  
Arterial Blood ◽  
Esophageal Balloon ◽  
Early Phases

Abstract Background. This study was conceived to provide systematic data about lung mechanics during early phases of CoVID-19 pneumonia, as long as to explore its variations during prone positioning. Methods. We enrolled four patients hospitalized in the Intensive Care Unit of “M. Bufalini” hospital, Cesena (Italy); after the positioning of an esophageal balloon, we measured mechanical power, respiratory system and transpulmonary parameters and arterial blood gases every 6 hours, just before decubitus change and 1 hour after prono-supination. Results. Both respiratory system and transpulmonary compliance and driving pressure confirmed the pseudo-normal respiratory mechanics of early CoVID-19 pneumonia (respectively, CRS 40.8 ml/cmH2O and DPRS 9.7 cmH2O; CL 53.1 ml/cmH2O and DPL 7.9 cmH2O). Interestingly, prone positioning involved a worsening in respiratory mechanical properties (CRS,SUP 56.3 ml/cmH2O and CRS,PR 41.5 ml/cmH2O – P 0.37; CL,SUP 80.8 ml/cmH2O and CL,PR 53.2 ml/cmH2O – P 0.23). Conclusions. Despite the severe ARDS pattern, respiratory system and lung mechanical properties during CoVID-19 pneumonia are pseudo-normal and tend to worsen during pronation. Trial registration. Restrospectively registered.

Respiratory Mechanics and Arterial Blood Gases During and After Laparoscopic Cholecystectomy

1997 ◽  
Vol 41 (1) ◽  
pp. 44
Author(s):  
H. IWASAKA ◽  
H. MIYAKAWA ◽  
H. YAMAMOTO ◽  
T. KITANO ◽  
R. TANIGUCHI ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Respiratory Mechanics ◽  
Blood Gases ◽  
Arterial Blood Gases ◽  
Arterial Blood

scholarly journals Change in Free Radical and Antioxidant Enzyme Levels in the Patients Undergoing Open Heart Surgery with Cardiopulmonary Bypass

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Fevzi Sarper Türker ◽  
Ayşe Doğan ◽  
Gonca Ozan ◽  
Kurtuluş Kıbar ◽  
Mine Erışır
Keyword(s):  
Cardiopulmonary Bypass ◽  
Oxidative Damage ◽  
Postoperative Period ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Early Postoperative Period ◽  
Open Heart ◽  
Arterial Blood ◽  
Antioxidant Parameters ◽  
Antioxidant Supplements

Objective. The purpose of this study is to determine the changes in oxidative damage and antioxidant parameters in open heart surgeries with cardiopulmonary bypass (CPB) in preoperative and early postoperative periods.Methods. A total of three consecutive arterial blood samples were obtained from the patients in the study group, in preoperative, early postoperative, and postoperative periods, respectively. Oxidative damage indicator (MDA) and antioxidant indicators (GPx, GSH, CAT, and SOD) were examined.Results. A statistically significant increase was observed in MDA level in postoperative period compared to preoperative and early postoperative periods. GSH levels and CAT activities increased significantly in early postoperative and postoperative periods. Analyses revealed an increase in GPx and SOD enzyme activities only in the postoperative period.Conclusion. Even though the increase in MDA level was suppressed by the increased GSH level and CAT activity like in early postoperative period, efficiency can be brought for the increases in insufficient significant antioxidant parameters in postoperative period by administering antioxidant supplements to the patients and thus the increase in MDA in postoperative period can be significantly suppressed.

Relationship between serum lactate and ionized calcium in open-heart surgery.

1986 ◽  
Vol 32 (10) ◽  
pp. 1849-1853 ◽  
Author(s):  
J Toffaletti ◽  
R H Christenson ◽  
S Mullins ◽  
R E Harris
Keyword(s):  
Linear Regression ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Blood Gases ◽  
Serum Lactate ◽  
Ionized Calcium ◽  
Open Heart ◽  
Total Calcium ◽  
Before And After ◽  
The Relationship

Abstract We studied 16 patients undergoing open-heart surgery and heart-lung bypass, to examine the relationship between ionized calcium and lactate. Blood was sampled at successive stages of the operation for measurement of ionized and total calcium, lactate, blood gases, pH, hematocrit, and other constituents. We found that correlations between ionized calcium and lactate were positive and statistically significant (p less than 0.05), both among and within patients. The linear regression of ionized calcium on lactate remained highly significant (p less than 0.0001) after adjustment for variability among patients and across operative stages as well as after correction for pH and hemodilution. The significant regressions between calcium and lactate, both before and after administration of calcium, indicate a relationship for calcium and lactate in patients undergoing open-heart surgery.

S-100ao protein in blood and urine during open-heart surgery.

1989 ◽  
Vol 35 (9) ◽  
pp. 1942-1944 ◽  
Author(s):  
A Usui ◽  
K Kato ◽  
T Abe ◽  
M Murase ◽  
M Tanaka ◽  
...  
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Mitral Valve Surgery ◽  
Open Heart ◽  
Arterial Blood ◽  
The Mean ◽  
Serial Samples ◽  
Mean Concentration ◽  
Coronary Sinus Blood

Abstract Concentrations of S100a0 protein and CK-MB were measured by enzyme immunoassay in serial samples of arterial and coronary-sinus blood and urine taken from 26 patients who were undergoing mitral valve surgery. The mean concentration of arterial S100a0 in plasma was 0.32 (SD 0.28) ng/mL at the beginning of anesthesia, increased sharply after reperfusion, peaking [14.4 (SD 6.63) ng/mL] after 45 min of reperfusion, then decreased rapidly. The concentration of creatine kinase (CK) isoenzyme MB in arterial blood plasma was greatest 3 h after reperfusion [107 (SD 54.5) ng/mL]. S100a0 concentrations in urine increased dramatically after reperfusion [16,300 (SD 12,000) ng/h vs 44 (SD 32) ng/h], while CK-MB increased slightly [135 (SD 75) ng/h vs 19 (SD 12) ng/h]. These results suggest that S100a0 in cardiac muscle is released into the bloodstream during open-heart surgery and is discharged into the urine more rapidly than is CK-MB. Determination of S100a0 in plasma or urine thus may be useful for estimating damage to heart muscle during open-heart surgery.

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