Six-minute walk test vs cardiopulmonary exercise test in the assessment of exercise tolerance in adults with cystic fibrosis

Author(s):  
Marcello Di Paolo ◽  
Daniela Savi ◽  
Serena Quattrucci ◽  
Luigi Graziano ◽  
Elisabetta Arcieri ◽  
...  
2020 ◽  
Vol 19 (4) ◽  
pp. 2561
Author(s):  
M. G. Bubnova ◽  
A. L. Persiyanova-Dubrova

Six-minute walk test (6MWT) is a simple and safe tool for assessing exercise tolerance in  various  categories  of  patients.  Currently,  6MWT  is  used to assess the functional status of a patient and determine the strategy of increasing physical activity, primarily in patients with reduced exercise tolerance and contraindications for cardiopulmonary exercise  test. The basic requirements for the 6MWT are presented, taking into account the factors affecting its  informativeness  and  accuracy,  as  well  as the interpretation of results. The diagnostic and prognostic value of 6MWT in different categories of patients are discussed. The prospects for 6MWT use in cardiac rehabilitation for planning rehabilitation program, prescribing exercises,  determining  the  risk   of   complications,   and   evaluating the effectiveness  are  considered.  The  limitations  of  6MWT  and  ways to overcome it, as well as directions for further research are presented.


2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i476-i477
Author(s):  
Wioletta Dziubek ◽  
Mariusz Kusztal ◽  
Katarzyna Bulińska ◽  
Bartosz Ochmann ◽  
Łukasz Rogowski ◽  
...  

Author(s):  
Vivian Z. Tan ◽  
Meredith Q. Lee ◽  
Daryl L. Wong ◽  
Katherin S. Huang ◽  
Melissa Y. Chan ◽  
...  

Background/Objective: To date, a validated Chinese (Mandarin) six-minute walk test (6MWT) translated instruction is not available. Translation of the Chinese 6MWT instruction is done in an ad hoc manner within the Chinese-speaking populations. This study aimed to develop a set of valid and reliable Chinese (Mandarin) instructions of the 6MWT. Methods: Translation was performed from the original English instruction via the recommended “Process of translation and adaptation of instruments” by the World Health Organization to generate the Chinese instructions. The Chinese instructions were tested with 52 healthy adult participants for its validity. Each participant underwent three 6MWTs and a cardiopulmonary exercise test. Randomization allowed participants to undergo the walk test in both the original English and the new Chinese instructions. Face and content validity, intra-rater and inter-rater reliability of the Chinese instructions of the 6MWT were established through the translation process. Criterion validity was established by analyzing the results of the 6MWT and cardiopulmonary exercise test. Results: Intraclass correlation coefficient for inter-rater reliability was excellent ([Formula: see text], 95% confidence [Formula: see text]–1.000). Similarly, the intra-rater reliability across the three raters was high (R1: [Formula: see text], 95% confidence interval [Formula: see text]–1.000; R2: [Formula: see text], 95% [Formula: see text]–1.000; R3: [Formula: see text], 95% [Formula: see text]–1.000). The 6-min walk distances collected from the Chinese and English instructed trials correlated positively with the maximal oxygen consumption ([Formula: see text], [Formula: see text]; [Formula: see text], [Formula: see text]). Conclusion: This is the first study to develop and validate the Chinese (Mandarin) instructions of the 6MWT, and the translation is as reliable and valid as the original English instructions.


2020 ◽  
Vol 127 (Suppl_1) ◽  
Author(s):  
Adeel Yousphi ◽  
Ayesha Bakhtiar ◽  
Adnaan Sheikh ◽  
Lan Yang ◽  
Shahkar A Khan ◽  
...  

Introduction: Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia that can present as orthostatic tachycardia, dizziness, nausea, and anxiety, and many other symptoms that can be debilitating enough to cause functional impairment. The cardiopulmonary exercise test (CPET) has become a reliable test for evaluating the functional capacity (fc) in POTS patients. The test requires utilization of a bicycle ergometer, blood pressure apparatus, ECG, pulse oximeter, and a face mask that measures the oxygen uptake and carbon dioxide release. The 6-minute walk test (6MWT) is another test that can also be utilized to assess fc in patients. Objective: The aim of this study is to differentiate whether the 6MWT and CPET give similar results with regards to fc in POTS patients. Methods: A total of 27 POTS patients visiting the clinic consented to participate in the voluntary study. There were 2 males and 25 females, with ages between 16 to 58 years. For the 6MWT, we used wrist worn pulse oximeter, electronic tablet device, sphygmomanometer and a lap counter. Patients walked in a straight flat corridor which was marked at 3 meter intervals, for six minutes. At the end of 6 minutes, patients were asked to stop and the six minute walk distance (6MWD) was recorded. The predicted 6MWD, the distance the patient was expected to walk based on patient’s sex, age, height and weight was calculated by the application installed on the tablet. The percentage of the predicted 6MWD that was actually walked by the patients was calculated (6MWD % predicted), and considered as their fc. Using the electronic medical records, we obtained their CPET fc results, where fc was calculated as a percentage of the predicted maximal oxygen uptake per unit body weight per unit time (VO 2max ) that was actually consumed. The VO 2max measurement depends on patient’s sex, age, weight and height. Pearson correlation coefficient was used to compare the results of the 6MWT (6MWD % predicted) and CPET (fc). Results: Pearson correlation coefficient shows that there is no linear association between the CPET (fc) results and 6MWT (6MWD % predicted) results in POTS patients, with p=0.3368. Conclusion: The results convey no statistically significant association between the CPET (fc) results and the 6MWT (6MWD % predicted) results in POTS patients; the results of the 6MWT were not similar to that of the CPET in terms of fc testing in POTS patients. This suggests that the 6MWT has limited utility in POTS patients.


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