scholarly journals Nebuliser hygiene in cystic fibrosis: evidence-based recommendations

Breathe ◽  
2020 ◽  
Vol 16 (2) ◽  
pp. 190328 ◽  
Author(s):  
Jane Bell ◽  
Lauren Alexander ◽  
Jane Carson ◽  
Amanda Crossan ◽  
John McCaughan ◽  
...  

Nebulised therapies are extensively used in the daily therapeutic management of cystic fibrosis both for mucociliary clearance and for the management of chronic infections. Extensive developments have been made in relation to nebulised drug delivery mechanisms and drug formulations, and guidelines have been prepared that have addressed the appropriate use of such therapies. However, due to these developments, a plethora of nebuliser devices and drug chambers exist, and frequently, the limited guidance provided in relation to nebuliser hygiene is to follow manufacturers' instructions. Such instructions are inconsistent and at times confusing, translating to an increase in the burden associated with nebuliser maintenance. An evidence-based universal guideline relating to nebuliser care and hygiene is urgently required that is applicable to both at-home use and inpatient use. This article reviews the scientific literature in order to propose an evidence-based approach to nebuliser hygiene to ensure optimum drug delivery, and infection prevention and control.Educational aimsTo understand the reasons why nebuliser hygiene is important.To give an overview of the current nebuliser care instructions that have been described by manufacturers, societies and the scientific literature.To outline the current nebuliser hygiene practices used by persons with cystic fibrosis in the home and hospital settings.To highlight areas that need further evaluation to promote optimum nebuliser care.To establish an evidence-based guideline for nebuliser hygiene in relation to cystic fibrosis.

2021 ◽  
Author(s):  
T. E. F. Abbott ◽  
A. J. Fowler ◽  
T. D. Dobbs ◽  
J. Gibson ◽  
T. Shahid ◽  
...  

AbstractObjectivesTo confirm the incidence of perioperative SARS-CoV-2 infection and associated mortality after surgery.Design and settingAnalysis of routine electronic health record data from National Health Service (NHS) hospitals in England.MethodsWe extracted data from Hospital Episode Statistics in England describing adult patients undergoing surgery between 1st January 2020 and 31st October 2020. The exposure was SARS-CoV-2 infection defined by ICD-10 codes. The primary outcome measure was 90-day in-hospital mortality. Data were analysed using multivariable logistic regression adjusted for age, sex, Charlson co-morbidity index, index of multiple deprivation, presence of cancer, surgical procedure type and admission acuity. Results are presented as n (%) and odds ratios (OR) with 95% confidence intervals.ResultsWe identified 1,972,153 patients undergoing surgery of whom 11,940 (0.6%) had SARS-CoV-2. In total, 19,100 (1.0%) patients died in hospital. SARS-CoV-2 infection was associated with a much greater risk of death (SARS-CoV-2: 2,618/11,940 [21.9%] vs No SARS-CoV-2: 16,482/1,960,213 [0.8%]; OR: 5.8 [5.5 – 6.1]; p<0.001). Amongst patients undergoing elective surgery 1,030/1,374,985 (0.1%) had SARS-CoV-2 of whom 83/1,030 (8.1%) died, compared with 1,092/1,373,955 (0.1%) patients without SARS-CoV-2 (OR: 29.0 [22.5 −37.3]; p<0.001). Amongst patients undergoing emergency surgery 9,742/437,891 (2.2%) patients had SARS-CoV-2, of whom 2,466/9,742 (25.3%) died compared with 14,817/428,149 (3.5%) patients without SARS-CoV-2 (OR: 5.7 [5.4 – 6.0]; p<0.001).ConclusionsThe low incidence of SARS-CoV-2 infection in NHS surgical pathways suggests current infection prevention and control policies are highly effective. However, the high mortality amongst patients with SARS-CoV-2 suggests these precautions cannot be safely relaxed.Summary boxesWhat is already known on this topicHigh mortality rates have been reported amongst surgical patients who develop COVID-19 but we don’t know how this compares to the concurrent surgical population unaffected by COVID-19.Strict infection prevention and control procedures have substantially reduced the capacity of surgical treatment pathways in many hospitals.The very large backlog in delayed and cancelled surgical procedures is a growing public health concern.What this study addsFewer than 1 in 100 surgical patients are affected by COVID-19 in the English National Health Service.Elective surgical patients who do develop COVID-19 are 30 times more likely to die while in hospital.Infection prevention and control procedures in NHS surgical pathways are highly effective but cannot be safely relaxed.


2021 ◽  
Vol 35 (3) ◽  
pp. 155-158
Author(s):  
JP Dadhich ◽  
Nupur Bidla

The COVID-19 pandemic has posed a serious challenge to the lactating women to practice optimal infant and young child feeding. Although international and national agencies developed appropriate evidence-based guidelines early in the pandemic, availability of this information to the mothers and their caregivers needs to be enhanced. This becomes important in view of apprehension about the risk of a decline in breastfeeding practices during the pandemic due to various factors. Any decrease in the breastfeeding rates may lead to increased childhood morbidity, mortality, and malnutrition. This article provides a glimpse of available evidence-based guidelines on breastfeeding by Covid-19 positive mothers and attempts by the baby food industry to exploit the situation by promoting their products. The article also deals with infection prevention and control measures to be observed by the mother while caring and breastfeeding her baby and other action required to protect breastfeeding from commercial influence.


2020 ◽  
Vol 19 (3) ◽  
pp. 384-387 ◽  
Author(s):  
Sonja Meyer ◽  
Thomas Nüßlein ◽  
Lutz Nährlich ◽  
Jutta Bend ◽  
Barbara Gärtner ◽  
...  

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Luís Irgang ◽  
Magnus Holmén ◽  
Fábio Gama ◽  
Petra Svedberg

PurposeFacilitation activities support implementation of evidence-based interventions within healthcare organizations. Few studies have attempted to understand how facilitation activities are performed to promote the uptake of evidence-based interventions in hospitals from resource-poor countries during crises such as pandemics. This paper aims to explore facilitation activities by infection prevention and control (IPC) professionals in 16 hospitals from 9 states in Brazil during the COVID-19 pandemic.Design/methodology/approachPrimary and secondary data were collected between March and December 2020. Semi-structured interviews were conducted with 21 IPC professionals in Brazilian hospitals during the COVID-19 pandemic. Public and internal documents were used for data triangulation. The data were analyzed through thematic analysis technique.FindingsBuilding on the change response theory, this study explores the facilitation activities from the cognitive, behavioral and affective aspects. The facilitation activities are grouped in three overarching dimensions: (1) creating and sustaining legitimacy to continuous and rapid changes, (2) fostering capabilities for continuous changes and (3) accelerating individual commitment.Practical implicationsDuring crises such as pandemics, facilitation activities by IPC professionals need to embrace all the cognitive, behavioral and affective aspects to stimulate positive attitudes of frontline workers toward continuous and urgent changes.Originality/valueThis study provides unique and timely empirical evidence on the facilitation activities that support the implementation of evidence-based interventions by IPC professionals during crises in hospitals in a resource-poor country.


2019 ◽  
Vol 10 (3) ◽  
Author(s):  
André Luiz Alvim ◽  
Braulio Couto

Objetivo: Desenvolver aplicativo para avaliação das práticas de higiene de mãos nos serviços de saúde, coletando dados no App e enviando as informações diretamente para formulário do Google Forms, de forma automatizada. Métodos: Trata-se de uma pesquisa de produção tecnológica contendo desenvolvimento de aplicativo para celular com sistema operacional Android 2.1 ou superior, desenvolvido na plataforma MIT App Inventor (appinventor.mit.edu/) e disponibilizado gratuitamente na Plataforma Google Play. Para avaliação de problemas de usabilidade através da interface com usuário, optou-se pela aplicação da heurística de Nielsen. Resultados: O aplicativo “Hands Clean pode ser acessado em: https://play.google.com/store/apps/details?id=appinventor.ai_coutobraulio.HC_Hands_Clean. Através da avaliação de problemas de usabilidade não foram detectados desvios classificados como catastrófico, grave e simples. Conclusão: O aplicativo mostrou-se uma excelente ferramenta para avaliação das práticas de higienização das mãos, contribuindo para direcionar as ações de prevenção e controle de infecções.Descritores: Aplicativos móveis; Informática em enfermagem; Infecção hospitalar.HANDS CLEAN - AUTOMATIC RATE FOR HAND HYGIENE: DEVELOPMENT OF APPLICATION FOR INFECTION CONTROLLERSObjective: To develop an app to evaluate hand hygiene practices in health services, collecting data in the App and sending the information directly to the Google Forms form, in an automated way. Methodology: This is a technology production survey containing mobile application development with Android 2.1+ operating system, developed on the MIT App Inventor platform and available for free on the Google Play Platform. In order to evaluate usability problems through the user interface, the Nielsen heuristic was applied. Results: Hands Clean app can be accessed at: https://play.google.com/store/apps/details?id=appinventor.ai_coutobraulio.HC_Hands_Clean.Through the evaluation of usability problems no problems classified as catastrophic, serious and simple were detected. Conclusion: The application proved to be an excellent tool to evaluate hand hygiene practices, contributing to better target infection prevention and control actions.Descriptors: Mobile Applications; Nursing Informatics; Cross Infection.HANDS CLEAN - TASA AUTOMÁTICA PARA HIGIENIZACIÓN DE LAS MANOS: DESARROLLO DE APLICACIÓN PARA CONTROLADORES DE INFECCIÓNObjetivo: Desarrollar aplicaciones para evaluar las prácticas de higiene de manos en los servicios de salud, recogiendo datos en la App y enviando la información directamente al formulario de Google Forms, de forma automatizada. Metodologia: Se trata de una investigación de producción tecnológica que contiene desarrollo de aplicaciones para móviles con sistema operativo Android 2.1 o superior, desarrollado en la plataforma MIT App Inventor y disponible gratuitamente en la Plataforma Google Play. Para la evaluación de problemas de usabilidad a través de la interfaz de usuario, se optó por la aplicación de la heurística de Nielsen. Resultados: Se puede acceder a la aplicación "Hands Clean" en: https://play.google.com/store/apps/details?id=appinventor.ai_coutobraulio.HC_Hands_Clean.A través de la evaluación de problemas de usabilidad no se detectaron problemas clasificados como catastrófico, grave y simple. Conclusión: La aplicación se mostró una excelente herramienta para evaluar las prácticas de higienización de las manos, contribuyendo a orientar mejor las acciones de prevención y control de infecciones. Descriptores: Aplicaciones móviles; Informática Aplicada a la Enfermería; Infección hospitalaria.


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