Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a randomized, double-blind, placebo-controlled trial

Objective: The purpose of the present study was to investigate the efficacy of combined omega-3 and Korean red ginseng supplementation on ADHD symptoms and cognitive function in children with subthreshold ADHD. Method: 120 children from 6 to 12 years with subthreshold ADHD were enrolled in this 12-week, double-blind, randomized, placebocontrolled study. The primary outcome was measured by Attention-Deficit Hyperactivity Disorder Rating Scale (ADHD-RS). Children Behavior Check List (CBCL), and neuropsychological tests assessing attention, memory, and executive function were included as secondary primary outcome measures. Results: Significant effects on the scores of ADHDRS, as well as several subscales of CBCL including ADHD and attention problem subscales were revealed. Conclusion: The combination of omega-3 and Korean red ginseng may have beneficial effects in children with subthreshold ADHD. Increased clinical awareness of ADHD symptoms even at a subthreshold level is needed.

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Effects of Korean Red Ginseng on Dry Mouth: A Randomized, Double-Blind, Placebo-Controlled Trial

Journal of Ginseng Research ◽

10.5142/jgr.2010.34.3.183 ◽

2010 ◽

Vol 34 (3) ◽

pp. 183-191 ◽

Cited By ~ 12

Author(s):

Jae-Woo Park ◽

Beom-Joon Lee ◽

Young-Min Bu ◽

In-Kwon Yeo ◽

Jin-Sung Kim ◽

...

Keyword(s):

Controlled Trial ◽

Dry Mouth ◽

Red Ginseng ◽

Korean Red Ginseng ◽

Double Blind ◽

Double Blind Placebo

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Efficacy and safety of Korean red ginseng for cold hypersensitivity in the hands and feet: A randomized, double-blind, placebo-controlled trial

Journal of Ethnopharmacology ◽

10.1016/j.jep.2014.09.028 ◽

2014 ◽

Vol 158 ◽

pp. 25-32 ◽

Cited By ~ 25

Author(s):

Kyoung-Sun Park ◽

Kang-In Park ◽

Jin-Woo Kim ◽

Young-Jin Yun ◽

Se-Hwa Kim ◽

...

Keyword(s):

Controlled Trial ◽

Efficacy And Safety ◽

Red Ginseng ◽

Korean Red Ginseng ◽

Double Blind ◽

Double Blind Placebo ◽

Hands And Feet ◽

Cold Hypersensitivity

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Supplementation with Korean Red Ginseng Improves Current Perception Threshold in Korean Type 2 Diabetes Patients: A Randomized, Double-Blind, Placebo-Controlled Trial

Journal of Diabetes Research ◽

10.1155/2020/5295328 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8

Author(s):

Kahui Park ◽

YuSik Kim ◽

Junghye Kim ◽

Shinae Kang ◽

Jong Suk Park ◽

...

Keyword(s):

Type 2 Diabetes ◽

Controlled Trial ◽

Diabetes Duration ◽

Red Ginseng ◽

Korean Red Ginseng ◽

Double Blind ◽

Perception Threshold ◽

Double Blind Placebo ◽

Current Perception Threshold

Background. Many Type 2 diabetes (T2DM) patients in Korea take Korean Red Ginseng (KRG) for various reasons. In this study, we investigated the effects of KRG administration on diabetic peripheral neuropathy in T2DM patients. Methods. This study was a randomized, double-blind, placebo-controlled trial. Participants were randomly allocated to either the placebo or KRG group and took corresponding tablets for 24 weeks. The primary outcomes were changes in current perception threshold (CPT) at week 24. Secondary outcomes were altered fasting plasma glucose, HbA1c, and various metabolic and inflammatory markers at week 24. Results. Sixty-one patients completed the study. The CPT of the lower extremities at various frequencies exhibited significant improvements at week 24 in the KRG group. Other metabolic parameters were not altered after 24 weeks in both groups. In the subgroup analysis, CPT levels were improved in those with a longer diabetes duration or who already had neuropathy at the beginning of the study, and insulin resistance was improved in patients with a shorter diabetes duration. Conclusion. Twenty-four week administration of KRG in T2DM patients resulted in a significant improvement in neuropathy, especially in those with a longer diabetes duration. A further, larger population study with a longer follow-up period is warranted to verify the effects of KRG on diabetic neuropathy.

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