scholarly journals Bioprosthetic mitral valve effective orifice area using 4D flow cardiac magnetic resonance derived time velocity integral. An in vitro comparison with Doppler Echocardiography

Author(s):  
Dimitrios Maragiannis ◽  
Matthew Jackson ◽  
Stephen Igo ◽  
Karen Chin ◽  
Kyle Autry ◽  
...  
Author(s):  
Yuichiro Kitada ◽  
Mamoru Arakawa ◽  
Homare Okamura ◽  
Kei Akiyoshi ◽  
Daijiro Hori ◽  
...  

Background and Aim of the Study: Negative impact of prosthesis-patient mismatch (PPM) on long term survival after valve replacement has been reported. However, the effect of PPM after bioprosthetic mitral valve replacement (MVR) has not yet been well examined. The purpose of this study was to investigate the effect of PPM on late outcomes after bioprosthetic MVR for mitral regurgitation (MR). Methods: A total of 181 patients underwent bioprosthetic MVR between April 2008 and December 2016. After excluding patients with mitral stenosis and those with incomplete data, 128 patients were included in the study. Postoperative transthoracic echocardiography was performed for all patients and the effective orifice area (EOA) was calculated using the pressure half-time method. The effective orifice area index (EOAI) was calculated by the formula: EOA/body surface area (BSA). PPM was defined as a postoperative EOAI ≤ 1.2 cm2/m2. The characteristics and outcomes were compared between the groups. Results: There were 34 patients (26.6%) with PPM and 94 patients (73.4%) without PPM. Although proportion of males and BSA were higher in the PPM group, valve size distributions were similar between the two groups. There were no significant differences in the in-hospital mortality and morbidities. Multivariable analysis showed that PPM was an independent predictor of late mortality (hazard ratio [HR] 3.38; 95% confidence interval [CI] 1.69-6.75; p = .001) and death from heart failure (HR 31.03, 95% CI 4.49-214.40, p < .001). Conclusions: PPM after MVR for MR was associated with long-term mortality and death from heart failure.


2015 ◽  
Vol 65 (10) ◽  
pp. A1296
Author(s):  
Dimitrios Maragiannis ◽  
Matthew Jackson ◽  
Jose Flores-Arrendondo ◽  
Paulino Alvarez ◽  
Autry Kyle ◽  
...  

2018 ◽  
Vol 4 (1) ◽  
pp. 149-151
Author(s):  
Michael Stiehm ◽  
Stefanie Kohse ◽  
Kerstin Schümann ◽  
Sebastian Kaule ◽  
Stefan Siewert ◽  
...  

AbstractVenous ulcers of the lower limbs are one clinical manifestation of chronic venous insufficiency. Currently, there is no venous valve prosthesis available. This study presents novel venous valve prostheses made of threedimensional electrospun fibrous nonwoven leaflets. The aim of this study was to prove the feasibility of the manufacturing process as well as to investigate design features of the venous valve prostheses from a hemodynamic point of view. An adapted pulse duplicator system (ViVitrolabs, Victoria, BC, CA) was used for characterization of the hydrodynamic performance. For eight different venous valve prototypes flow rate, effective orifice area and regurgitation fraction was investigated in vitro. In particular, tricusp valve designs showed an up to 40% higher effective orifice area as well as 15% higher maximum flowrate compared to bicusp valve designs. However, the regurgitation fraction of the bicusp valve designs is up to 86% lower compared to tricusp valve. Additionally, the hemodynamic performance of the tricuspid valves showed a high sensitivity regarding the leaflet length. Bicuspid valves are less sensitive to changes of design parameters, more sufficient and therefore highly reliable.


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