scholarly journals Folic acid deficiency optic neuropathy: A case report

2008 ◽  
Vol 2 (1) ◽  
Author(s):  
Punyanganie de Silva ◽  
Gerard Jayamanne ◽  
Robin Bolton
Blood ◽  
1953 ◽  
Vol 8 (2) ◽  
pp. 175-181 ◽  
Author(s):  
H. O. NIEWEG ◽  
A. ARENDS

Abstract Atrophy of the spleen was observed in 3 cases of nontropical sprue, 1 case of chronic glomerulonephritis and 1 case of Whipple's disease. The occurrence of orthochromatic normoblasts and Howell-Jolly bodies in the peripheral blood in the absence of splenectomy may be a manifestation of atrophy of the spleen. Folic acid therapy was tried in 1 case and resulted in the disappearance of the orthochromatic normoblasts and fragmentation of the Howell-Jolly bodies. Some arguments are put forward in favor of the conception that atrophy of the spleen may be caused by a disturbance of cell regeneration due to a chronic folic acid deficiency.


2002 ◽  
Vol 216 (1) ◽  
pp. 65-67 ◽  
Author(s):  
Cynthia T. Hsu ◽  
Neil R. Miller ◽  
Misty L. Wray

2021 ◽  
Vol 14 (7) ◽  
pp. e242399
Author(s):  
Karina Pique ◽  
William Taber ◽  
Anthony Thompson ◽  
Charles Gerry Maitland

Isolated optic neuropathy due to folate deficiency is rarely reported. Poor dietary practices, malabsorption, and tobacco/alcohol abuse are usually responsible. We examined a patient with blinding optic neuropathies and isolated folic acid deficiency. Visual acuity recovered after folate replacement. At the same time, serological investigation revealed high ferritin and iron saturation levels with negative genetic markers for haemochromatosis consistent with the diagnosis of iron overload syndrome. There are no reports of blindness associated with iron overload syndrome.


2020 ◽  
Vol 61 (10) ◽  
pp. 1235-1239
Author(s):  
Sangbum Kim ◽  
Jongyeop Park ◽  
Seungwoo Lee ◽  
Junwoo Chun

The Lancet ◽  
1959 ◽  
Vol 274 (7110) ◽  
pp. 1033-1034 ◽  
Author(s):  
H.H. Francis ◽  
J.S. Scott

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