scholarly journals Cardiac troponin and skeletal muscle oxygenation in severe post-partum haemorrhage

Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 5) ◽  
pp. S8 ◽  
Author(s):  
Laurent Heyer ◽  
Alexandre Mebazaa ◽  
Etienne Gayat ◽  
Matthieu Resche-Rigon ◽  
Christophe Rabuel ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cardiac Troponin ◽  
Post Partum ◽  
Muscle Oxygenation ◽  
Skeletal Muscle Oxygenation ◽  
Post Partum Haemorrhage

Oxygen delivery-utilization mismatch in contracting locomotor muscle in COPD: peripheral factors

2015 ◽  
Vol 308 (2) ◽  
pp. R105-R111 ◽  
Author(s):  
Wladimir M. Medeiros ◽  
Mari C. T. Fernandes ◽  
Diogo P. Azevedo ◽  
Flavia F. M. de Freitas ◽  
Beatriz C. Amorim ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Near Infrared ◽  
Neuromuscular Electrical Stimulation ◽  
Muscle Oxygenation ◽  
Whole Body ◽  
Chronic Obstructive ◽  
Copd Patients ◽  
Skeletal Muscle Oxygenation ◽  
Severe Copd

Central cardiorespiratory and gas exchange limitations imposed by chronic obstructive pulmonary disease (COPD) impair ambulatory skeletal muscle oxygenation during whole body exercise. This investigation tested the hypothesis that peripheral factors per se contribute to impaired contracting lower limb muscle oxygenation in COPD patients. Submaximal neuromuscular electrical stimulation (NMES; 30, 40, and 50 mA at 50 Hz) of the quadriceps femoris was employed to evaluate contracting skeletal muscle oxygenation while minimizing the influence of COPD-related central cardiorespiratory constraints. Fractional O2 extraction was estimated by near-infrared spectroscopy (deoxyhemoglobin/myoglobin concentration; deoxy-[Hb/Mb]), and torque output was measured by isokinetic dynamometry in 15 nonhypoxemic patients with moderate-to-severe COPD (SpO2 = 94 ± 2%; FEV1 = 46.4 ± 10.1%; GOLD II and III) and in 10 age- and gender-matched sedentary controls. COPD patients had lower leg muscle mass than controls (LMM = 8.0 ± 0.7 kg vs. 8.9 ± 1.0 kg, respectively; P < 0.05) and produced relatively lower absolute and LMM-normalized torque across the range of NMES intensities ( P < 0.05 for all). Despite producing less torque, COPD patients had similar deoxy-[Hb/Mb] amplitudes at 30 and 40 mA ( P > 0.05 for both) and higher deoxy-[Hb/Mb] amplitude at 50 mA ( P < 0.05). Further analysis indicated that COPD patients required greater fractional O2 extraction to produce torque (i.e., ↑Δdeoxy-[Hb/Mb]/torque) relative to controls ( P < 0.05 for 40 and 50 mA) and as a function of NMES intensity ( P < 0.05 for all). The present data obtained during submaximal NMES of small muscle mass indicate that peripheral abnormalities contribute mechanistically to impaired contracting skeletal muscle oxygenation in nonhypoxemic, moderate-to-severe COPD patients.

scholarly journals Changes in skeletal muscle oxygenation during exercise measured by near-infrared spectroscopy on ascent to altitude

Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 5) ◽  
pp. S7 ◽  
Author(s):  
Daniel S Martin ◽  
Denny ZH Levett ◽  
Michael Mythen ◽  
Mike PW Grocott ◽  
Keyword(s):  
Skeletal Muscle ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Muscle Oxygenation ◽  
Skeletal Muscle Oxygenation

scholarly journals Image-based modelling of skeletal muscle oxygenation

2017 ◽  
Vol 14 (127) ◽  
pp. 20160992 ◽  
Author(s):  
B. Zeller-Plumhoff ◽  
T. Roose ◽  
G. F. Clough ◽  
P. Schneider
Keyword(s):  
Skeletal Muscle ◽  
Blood Vessel ◽  
Ex Vivo ◽  
Imaging Techniques ◽  
Muscle Oxygenation ◽  
Skeletal Muscle Oxygenation ◽  
Health And Disease ◽  
Vessel Networks

The supply of oxygen in sufficient quantity is vital for the correct functioning of all organs in the human body, in particular for skeletal muscle during exercise. Disease is often associated with both an inhibition of the microvascular supply capability and is thought to relate to changes in the structure of blood vessel networks. Different methods exist to investigate the influence of the microvascular structure on tissue oxygenation, varying over a range of application areas, i.e. biological in vivo and in vitro experiments, imaging and mathematical modelling. Ideally, all of these methods should be combined within the same framework in order to fully understand the processes involved. This review discusses the mathematical models of skeletal muscle oxygenation currently available that are based upon images taken of the muscle microvasculature in vivo and ex vivo . Imaging systems suitable for capturing the blood vessel networks are discussed and respective contrasting methods presented. The review further informs the association between anatomical characteristics in health and disease. With this review we give the reader a tool to understand and establish the workflow of developing an image-based model of skeletal muscle oxygenation. Finally, we give an outlook for improvements needed for measurements and imaging techniques to adequately investigate the microvascular capability for oxygen exchange.

Slower Skeletal Muscle Oxygenation Kinetics in Adults With Complex Congenital Heart Disease

2019 ◽  
Vol 35 (12) ◽  
pp. 1815-1823 ◽  
Author(s):  
Camilla Sandberg ◽  
Albert G. Crenshaw ◽  
Guilherme H. Elçadi ◽  
Christina Christersson ◽  
Joanna Hlebowicz ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Muscle Oxygenation ◽  
Complex Congenital Heart Disease ◽  
Skeletal Muscle Oxygenation

Effects of Ultratrail Running on Skeletal-Muscle Oxygenation Dynamics

2017 ◽  
Vol 12 (4) ◽  
pp. 496-504 ◽  
Author(s):  
Gianluca Vernillo ◽  
Alfredo Brighenti ◽  
Eloisa Limonta ◽  
Pietro Trabucchi ◽  
Davide Malatesta ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Vastus Lateralis ◽  
Oxygenation Index ◽  
Constant Load ◽  
Negative Influence ◽  
Muscle Oxygenation ◽  
Vastus Lateralis Muscle ◽  
Skeletal Muscle Oxygenation ◽  
Power Outputs ◽  
And Function

Purpose:To quantify changes in skeletal-muscle oxygenation and pulmonary O2 uptake (V̇O2) after an extreme ultratrail running bout.Methods:Before (PRE) and after (POST) the race (330-km, 24000 D±), profiles of vastus lateralis muscle oxygenation (ie, oxyhemoglobin [O2Hb], deoxyhemoglobin [HHb], and tissue oxygenation index [TOI]) and V̇O2 were determined in 14 athletes (EXP) and 12 control adults (CON) during two 4-min constant-load cycling bouts at power outputs of 1 (p1) and 1.5 (p1.5) W/kg performed in randomized order.Results:At POST, normalized [HHb] values increased (p1, +38.0%; p1.5, +27.9%; P < .05), while normalized [O2Hb] (p1, –20.4%; p1.5, –14.4%; P < .05) and TOI (p1, –17.0%; p1.5, –17.7%; P < .05) decreased in EXP. V̇O2 values were similar (P > 0.05). An “overshoot“ in normalized [HHb]:V̇O2 was observed, although the increase was significant only during p1.5 (+58.7%, P = .003). No difference in the aforementioned variables was noted in CON (P > .05).Conclusions:The concentric and, particularly, the eccentric loads characterizing this extreme ultratrail-running bout may have led to variations in muscle structure and function, increasing the local muscle deoxygenation profile and the imbalance between O2 delivery to working muscles and muscle O2 consumption. This highlights the importance of incorporating graded training, particularly downhill bouts, to reduce the negative influence of concentric and severe eccentric loads to the microcirculatory function and to enhance the ability of runners to sustain such loading.

scholarly journals Dynamics of skeletal muscle oxygenation during sequential bouts of moderate exercise

2005 ◽  
Vol 90 (3) ◽  
pp. 393-401 ◽  
Author(s):  
Leonardo F. Ferreira ◽  
Barbara J. Lutjemeier ◽  
Dana K. Townsend ◽  
Thomas J. Barstow
Keyword(s):  
Skeletal Muscle ◽  
Muscle Oxygenation ◽  
Moderate Exercise ◽  
Skeletal Muscle Oxygenation

The Effects Of Incremental Treadmill Walking On Skeletal Muscle Oxygenation In Older Cardiovascular Rehabilitation Participants

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S225
Author(s):  
Gregory Martel ◽  
Ryan Fleming ◽  
Timothy Garrison ◽  
Barak Kraus ◽  
Arthur Scofield ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Treadmill Walking ◽  
Muscle Oxygenation ◽  
Cardiovascular Rehabilitation ◽  
Skeletal Muscle Oxygenation
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