scholarly journals Cerebral microbleeds shouldn’t dictate treatment of acute stroke: a retrospective cohort study evaluating risk of intracerebral hemorrhage

BMC Neurology ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Martin A. Chacon-Portillo ◽  
Rafael H. Llinas ◽  
Elisabeth B. Marsh
Keyword(s):  
Cohort Study ◽  
Intracerebral Hemorrhage ◽  
Acute Stroke ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Cerebral Microbleeds

ROLE OF COMPUTED TOMOGRAPHY SCAN IN EVALUATION OF NEUROLOGICAL MANIFESTATIONS IN COVID 19 POSITIVE PATIENTS AND ITS CORRELATION WITH D-DIMER VALUE AND GCS: A RETROSPECTIVE COHORT STUDY IN A TERTIARY CARE HOSPITAL IN CENTRAL INDIA

2021 ◽  
pp. 17-21
Author(s):  
Debraj Saha ◽  
Aarti Anand ◽  
Jawahar Rathod ◽  
Prajwaleet Gour ◽  
Shivprasad Jaybhay ◽  
...  
Keyword(s):  
Cohort Study ◽  
Acute Stroke ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Neurological Symptoms ◽  
Government Medical College ◽  
Stroke Patients ◽  
Medical College ◽  
Neuro Imaging ◽  
D Dimer

Objective: To investigate the incidence and spectrum of neuroimaging ndings and their prognostic role in hospitalized COVID-19 patients in Government Medical College Nagpur along with their correlation with D-Dimer Values and GCS . Methods: This is a retrospective cohort study of 774 COVID-19 conrmed patients admitted to Government Medical College st st Nagpur between 1 April 2020 and 31 October 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuro-radiologists evaluated all neuroimaging studies for acute neuroimaging ndings related to COVID-19. Plasma D-dimer levels were measured using a particle-enhanced, immunoturbidimetric assay on admission in the 116 patients who came for evaluation of neurological symptoms. Moreover ,the patients were classied into different groups as mild, moderate and severe based on their GCS scores and was assessed with respect to their neuro-imaging ndings. Results: 15 % of the admitted patients suffered from neurological symptoms. Acute stroke was the most common nding in the patients with positive neuroimaging ndings resulting in 34.4% of the patients with positive neuroimaging ndings. Other ndings were subacute infarcts (13.8%), Chronic lacunar infarcts (20.6%) , Intraparenchymal hemorrhage in 10.4 %, hypertensive encephalopathy in 7 % and subarachanoid hemorrhage in 3.4 %. Plasma median D-dimer levels were signicantly (P฀ =฀ 0.000) higher in Acute stroke patients as compared to COVID 19 positive patients who had negative CT scan imaging features(0.88; interquartile range [IQR], 0.28–2.11 mg/L and 0.31; IQR, 0.17–0.74 mg/L). Patients who have positive neuroimaging ndings presented with a lower GCS whereas patients who had negative neuroimaging ndings presented with a higher GCS. Conclusions: Our study demonstrates acute stroke is the most common neuroloimaging nding in hospitalized COVID 19 Patients. Moreover D-Dimer values are highly predictive of acute ischemic stroke. Patients with positive neuro-imaging ndings have poor GCS scores.

Intervention by Speech Therapists to Promote Oral Intake of Patients with Acute Stroke: A Retrospective Cohort Study

2017 ◽  
Vol 26 (3) ◽  
pp. 480-487 ◽  
Author(s):  
Tomoko Nakazora ◽  
Junko Maeda ◽  
Konosuke Iwamoto ◽  
Sayori Hanashiro ◽  
Yoshikazu Nakamura ◽  
...  
Keyword(s):  
Cohort Study ◽  
Acute Stroke ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Oral Intake ◽  
Speech Therapists

scholarly journals Early intervention to promote oral feeding in patients with intracerebral hemorrhage: a retrospective cohort study

BMC Neurology ◽  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Hideaki Takahata ◽  
Keisuke Tsutsumi ◽  
Hiroshi Baba ◽  
Izumi Nagata ◽  
Masahiro Yonekura
Keyword(s):  
Cohort Study ◽  
Early Intervention ◽  
Intracerebral Hemorrhage ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Oral Feeding

scholarly journals Stroke care and case fatality in people with and without schizophrenia: a retrospective cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e044766
Author(s):  
Moira K Kapral ◽  
Paul Kurdyak ◽  
Leanne K Casaubon ◽  
Jiming Fang ◽  
Joan Porter ◽  
...  
Keyword(s):  
Cohort Study ◽  
Acute Stroke ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Case Fatality ◽  
Stroke Care ◽  
Lipid Lowering ◽  
Stroke Severity ◽  
Processes Of Care ◽  
Stroke Case

BackgroundSchizophrenia is associated with an increased risk of death following stroke; however, the magnitude and underlying reasons for this are not well understood.ObjectiveTo determine the association between schizophrenia and stroke case fatality, adjusting for baseline characteristics, stroke severity and processes of care.DesignRetrospective cohort study used linked clinical and administrative databases.SettingAll acute care institutions (N=152) in the province of Ontario, Canada.ParticipantsAll patients (N=52 473) hospitalised with stroke between 1 April 2002 and 31 March 2013 and included in the Ontario Stroke Registry. Those with schizophrenia (n=612) were identified using validated algorithms.Main outcomes and measuresWe compared acute stroke care in those with and without schizophrenia and used Cox proportional hazards models to examine the association between schizophrenia and mortality, adjusting for demographics, comorbidity, stroke severity and processes of care.ResultsCompared with those without schizophrenia, people with schizophrenia were less likely to undergo thrombolysis (10.1% vs 13.4%), carotid imaging (66.3% vs 74.0%), rehabilitation (36.6% vs 46.6% among those with disability at discharge) or be treated with antihypertensive, lipid-lowering or anticoagulant therapies. After adjustment for age and other factors, schizophrenia was associated with death from any cause at 1 year (adjusted HR (aHR) 1.33, 95% CI 1.14 to 1.54). This was mainly attributable to early deaths from stroke (aHR 1.47, 95% CI 1.20 to 1.80, with survival curves separating in the first 30 days), and the survival disadvantage was particularly marked in those aged over 70 years (1-year mortality 46.9% vs 35.0%).ConclusionsSchizophrenia is associated with increased stroke case fatality, which is not fully explained by stroke severity, measurable comorbid conditions or processes of care. Future work should focus on understanding this mortality gap and on improving acute stroke and secondary preventive care in people with schizophrenia.

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