scholarly journals Study protocol of a cluster randomized controlled trial of strategies to increase antenatal iron and folic acid supplementation and malaria prophylaxis in rural south-central Côte d’Ivoire

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Siaka Koné ◽  
Jürg Utzinger ◽  
Nicole Probst-Hensch ◽  
Daouda Dao ◽  
Günther Fink
Keyword(s):  
Pregnant Women ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Folic Acid Supplementation ◽  
Cote D’Ivoire ◽  
Malaria Chemoprophylaxis ◽  
South Central ◽  
Côte D'ivoire ◽  
Cluster Randomized ◽  
The Cost

Abstract Background Coverage of antenatal iron and folic acid supplementation (IFAS) and intermittent preventive treatment of malaria in pregnancy (IPTp) remains low in many countries. Evidence on the most effective ways to increase both IFASIPTp is mixed overall, with only few studies directly identifying cost-effective ways to increase coverage of both interventions. The proposed study aims to assess the cost, impact and relative cost-effectiveness of two complementary strategies of increasing IFAS and malaria chemoprophylaxis coverage among pregnant women relative to the current default system in a rural low-income setting of sub-Saharan Africa. Methods/design This study will be carried out in the Taabo health and demographic surveillance system (HDSS) in south-central Côte d’Ivoire. This is a cluster-randomized trial targeting 720 consenting pregnant women aged ≥15 years. The 118 clusters constituting the Taabo HDSS monitoring area will be randomly allocated to one of the following three groups with equal probability: a control group, an information only group, and an information plus home delivery group. To assess the relative effectiveness of each strategy, we will conduct an endline survey within the first 2 weeks after delivery. The primary outcomes of the trial will be maternal post-partum anaemia and malaria infection. Anaemia will be assessed using HEMOCUE devices; malaria infections will be assessed using standard rapid diagnostic tests named CareStart™ Malaria Pf (HRP2) Ag RDT (Multi Kit with capped lancet and inverted cup specimen transfer device). Other outcomes will include self-reported adherence to supplementation and malaria chemoprophylaxis, as well as miscarriages, stillbirths and low birth weight deliveries. Discussion This study will assess the cost-effectiveness of two alternative strategies to increase antenatal IFAS and malaria chemoprophylaxis coverage among pregnant women in rural Côte d’Ivoire and similar settings. Trial registration ClinicalTrials.govNCT04250428; Registered 31 January 2020.

scholarly journals Etiology of Anemia Among Infants, School-Aged Children, and Young Non-Pregnant Women in Different Settings of South-Central Côte d'Ivoire

2012 ◽  
Vol 87 (3) ◽  
pp. 425-434 ◽  
Author(s):  
Aurélie A. Righetti ◽  
Dominik Glinz ◽  
Sébastien Niamké ◽  
Lukas G. Adiossan ◽  
Eliézer K. N'Goran ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Cote D’Ivoire ◽  
School Aged Children ◽  
South Central ◽  
Côte D'ivoire

Haematological characteristics and HIV status of pregnant women in Abidjan, Côte d'Ivoire, 1995–1996

1999 ◽  
Vol 93 (4) ◽  
pp. 419-422 ◽  
Author(s):  
Rosa Ramon ◽  
Duni Sawadogo ◽  
Fatoumata Sylla Koko ◽  
Valentin Noba ◽  
Ruffin Likikouët ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Hiv Status ◽  
Cote D’Ivoire ◽  
Côte D'ivoire

Prevalence, Risk Factors and Morbidity Profile of Schistosoma Infection Among Adults in the Taabo Health and Demographic Surveillance System, South-central Côte d’Ivoire

2021 ◽  
Author(s):  
Fidèle K. Bassa ◽  
Ikenna C. Eze ◽  
Rufin K. Assaré ◽  
Clémence Essé ◽  
Siaka Koné ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cote D'ivoire ◽  
Surveillance System ◽  
Côte D’Ivoire ◽  
Demographic Surveillance System ◽  
Urine Samples ◽  
Health Examination ◽  
Cote D’Ivoire ◽  
South Central ◽  
Côte D'ivoire

Abstract Background: Schistosomiasis remains an important public health issue among adults and infected individuals not treated serve as a reservoir of the parasite. Despite this fact, evidence on the epidemiology of schistosomiasis in adults in Côte d’Ivoire is scanty. This study aimed to determine the prevalence and risk factors of schistosomiasis among adults in the Taabo health and demographic surveillance system in the south-central part of Côte d’Ivoire.Methods: A cross-sectional survey was carried out in April and May 2017 in the frame of the “Côte d’Ivoire Dual Burden of Disease Study” (CoDuBu). A total of 901 randomly selected individuals, aged 18-90 years, provided blood, stool and urine samples for the diagnosis of malaria and helminth infections. With an emphasis on schistosomiasis, stool samples were subjected to the Kato-Katz technique for detection of Schistosoma mansoni eggs, while urine samples were examined for eggs of Schistosoma haematobium and circulating cathodic antigen of S. mansoni. Risk factors and morbidity profiles were assessed using health examination and questionnaires. Multinomial logistic regressions were employed to identify independent risk factors and morbidity patterns associated with S. mansoni mono- and co-infections.Results: The prevalence of S. mansoni and S. haematobium was 23.2% and 1.0%, respectively. Most S. mansoni were mono-infections (81.3%). Independent determinants of S. mansoni infection were young age, low socioeconomic status (mono- and co-infection) and poor hygiene practices (co-infection). S. mansoni infection was independently associated with higher pain and symptom scores (mono-infection), poor self-rated health and low healthcare use (co-infection).Conclusions: This study showed that adults represent a substantial reservoir of S. mansoni. To sustain schistosomiasis control and improve people’s wellbeing, it is important to expand preventive chemotherapy from school-aged children to adults, coupled with hygiene and health education.

scholarly journals Premières données sur les variations saisonnières de la communauté d’oiseaux du barrage urbain de Koko (Korhogo, Côte d’Ivoire)

2019 ◽  
Vol 41.2 ◽  
pp. 6926-6939
Author(s):  
NIAMIEN Coffi Jean Magloire ◽  
KONAN Ekoun Michaël ◽  
ODOUKPE Kadio Saint Guillaume ◽  
YAOKOKORE-BEIBRO Kouassi Hilaire ◽  
N’GORAN Kouakou Eliézer
Keyword(s):  
Cote D'ivoire ◽  
Rainy Season ◽  
Côte D’Ivoire ◽  
Well Being ◽  
Dry Season ◽  
Resident Species ◽  
Cote D’Ivoire ◽  
South Central ◽  
Frequent Species ◽  
Côte D'ivoire

Les oiseaux rendent d’importants services écologiques nécessaires au bien-être de l’homme. En Côte d’Ivoire, l’essentiel des études ornithologiques se sont déroulées au sud, et accessoirement au centre et au centre-ouest. En outre, très peu de travaux ont porté sur les zones humides. La ville de Korhogo abrite des barrages à vocation agro-pastorale qui n’ont été l’objet d’aucune étude. Pour combler ce manque de connaissance, une étude a été menée de février 2016 à janvier 2017. L’objectif de ce travail est d’évaluer la richesse spécifique et de déterminer l’influence des saisons sur la distribution qualitative de la communauté des oiseaux du barrage urbain de Koko dans la commune de Korhogo. Pour ce faire, des observations directes, utilisant la méthode des transects ponctuée d’arrêts d’environ 15 minutes, ont été effectuées. Les résultats indiquent que cette communauté est constituée de 63 espèces d’oiseaux appartenant à 32 familles et regroupées en 14 ordres. Globalement, l’ordre des Passériformes et la famille des Ardeidae sont les mieux représentés. Du point de vue de leur statut biogéographique, les espèces résidentes (37 individus : 59 %) et accidentelles (23 individus : 36,51%) sont majoritaires. Le plus grand nombre d’espèces a été observé en saison des pluies (52 individus : 82,54%). Sept espèces ont été spécifiques de la saison sèche alors que trois espèces sont caractéristiques de la saison des pluies. Les espèces résidentes ont été les nombreuses en toute saison. Au niveau structural, les espèces accessoires, les espèces assez-fréquentes et les espèces fréquentes ont été les mieux représentées en saison sèche tandis que les espèces assez-fréquentes ont été majoritaires en saison des pluies. Cette étude confirme la distribution des communautés des oiseaux selon les saisons. ABSTRACT Birds provide important ecosystem services necessary for human well-being. In Côte d'Ivoire, ornithological studies were carried out in the south, central and central-west. In addition, very little work has been done on wetlands. The Commune of Korhogo is home to agro-pastoral dams that have not been studied. To fill in this gap of information, a study was conducted from February 2016 to January 2017. The aim of this study was to assess the specific richness and to examine the effect of seasons on the qualitative distribution of the Koko urban dam birds’ community. Direct observations using the method of line transects with a 15 minutes points were carried out. Results show that this community consists of 63 species of birds belonging to 32 families and grouped in 14 orders. Globally, the order of the Passeriformes and the family of Ardeidae were the best represented. In terms of their biogeographical status, resident species (37 individuals: 59%) and accidental species (23 individuals: 36.51%) were dominant. The high number of bird species was observed during the rainy season (52 individuals: 82.54%). Seven species were specific to the dry season while three species are characteristic of the rainy season. Resident species were numerous in all seasons. The accessory and relatively frequent species have been the most abundant during the dry season while the fairly frequent species were predominant in the rainy season. This study confirms the distribution of bird communities according to the seasons.

scholarly journals Mild riboflavin deficiency is highly prevalent in school-age children but does not increase risk for anaemia in Côte d'Ivoire

2007 ◽  
Vol 97 (5) ◽  
pp. 970-976 ◽  
Author(s):  
Fabian Rohner ◽  
Michael B. Zimmermann ◽  
Rita Wegmueller ◽  
Andreas B. Tschannen ◽  
Richard F. Hurrell
Keyword(s):  
Iron Deficiency ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
School Age Children ◽  
Riboflavin Deficiency ◽  
Cote D’Ivoire ◽  
South Central ◽  
Côte D'ivoire ◽  
Iron Deficient ◽  
Riboflavin Deficient

There are few data on the prevalence of riboflavin deficiency in sub-Saharan Africa, and it remains unclear whether riboflavin status influences the risk for anaemia. The aims of this study were to: (1) measure the prevalence of riboflavin deficiency in children in south-central Côte d'Ivoire; (2) estimate the riboflavin content of the local diet; and (3) determine if riboflavin deficiency predicts anaemia and/or iron deficiency. In 5- to 15-year-old children (n281), height, weight, haemoglobin (Hb), whole blood zinc protoporphyrin (ZPP), erythrocyte glutathione reductase activity coefficient (EGRAC), serum retinol, C-reactive protein (CRP) and prevalence ofPlasmodiumspp. (asymptomatic malaria) andSchistosoma haematobium(bilharziosis) infections were measured. Three-day weighed food records were kept in twenty-four households. Prevalence of anaemia in the sample was 52 %; 59 % were iron-deficient based on an elevated ZPP concentration, and 36 % suffered from iron deficiency anaemia.Plasmodiumparasitaemia was found in 49 % of the children. Nineteen percent of the children were infected withS. haematobium. Median riboflavin intake in 5- to 15-year-old children from the food records was 0·42 mg/d, ~47 % of the estimated average requirement for this age group. Prevalence of riboflavin deficiency was 65 %, as defined by an EGRAC value >1·2. Age, elevated CRP and iron deficiency were significant predictors of Hb. Riboflavin-deficient children free of malaria were more likely to be iron deficient (odds ratio; 3·07; 95 % CI 1·12, 8·41). In conclusion, nearly two-thirds of school-age children in south-central Côte d'Ivoire are mildly riboflavin deficient. Riboflavin deficiency did not predict Hb and/or anaemia, but did predict iron deficiency among children free of malaria.

scholarly journals Cost-Effectiveness of Preemptive Switching to Efavirenz-Based Antiretroviral Therapy for Children With Human Immunodeficiency Virus

2019 ◽  
Vol 6 (7) ◽  
Author(s):  
Sophie Desmonde ◽  
Simone C Frank ◽  
Ashraf Coovadia ◽  
Désiré L Dahourou ◽  
Taige Hou ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Cost Saving ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Virologic Failure ◽  
Lifetime Cost ◽  
Second Line ◽  
Cote D’Ivoire ◽  
Côte D'ivoire ◽  
The Cost

Abstract Background The NEVEREST-3 (South Africa) and MONOD-ANRS-12206 (Côte d’Ivoire, Burkina Faso) randomized trials found that switching to efavirenz (EFV) in human immunodeficiency virus–infected children >3 years old who were virologically suppressed by ritonavir-boosted lopinavir (LPV/r) was noninferior to continuing o LPV/r. We evaluated the cost-effectiveness of this strategy using the Cost-Effectiveness of Preventing AIDS Complications–Pediatric model. Methods We examined 3 strategies in South African children aged ≥3 years who were virologically suppressed by LPV/r: (1) continued LPV/r, even in case of virologic failure, without second-line regimens; continued on LPV/r with second-line option after observed virologic failure; and preemptive switch to EFV-based antiretroviral therapy (ART), with return to LPV/r after observed virologic failure. We derived data on 24-week suppression (<1000 copies/mL) after a switch to EFV (98.4%) and the subsequent risk of virologic failure (LPV/r, 0.23%/mo; EFV, 0.15%/mo) from NEVEREST-3 data; we obtained ART costs (LPV/r, $6–$20/mo; EFV, $3–$6/mo) from published sources. We projected discounted life expectancy (LE) and lifetime costs per person. A secondary analysis used data from MONOD-ANRS-12206 in Côte d’Ivoire. Results Continued LPV/r led to the shortest LE (18.2 years) and the highest per-person lifetime cost ($19 470). LPV/r with second-line option increased LE (19.9 years) and decreased per-person lifetime costs($16 070). Switching led to the longest LE (20.4 years) and the lowest per-person lifetime cost ($15 240); this strategy was cost saving under plausible variations in key parameters. Using MONOD-ANRS-12206 data in Côte d’Ivoire, the Switch strategy remained cost saving only compared with continued LPV/r, but the LPV/r with second-line option strategy was cost-effective compared with switching. Conclusion For children ≥3 years old and virologically suppressed by LPV/r-based ART, preemptive switching to EFV can improve long-term clinical outcomes and be cost saving. Clinical Trials Registration NCT01127204

scholarly journals Evaluation of the oral health of pregnant women in prenatal consultations in Côte d’Ivoire

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
G D Meless ◽  
J C Guinan ◽  
A D Sangaré ◽  
M Traoré ◽  
A A Amangoua ◽  
...  
Keyword(s):  
Oral Health ◽  
Pregnant Women ◽  
Cote D'ivoire ◽  
Oral Hygiene ◽  
Côte D’Ivoire ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Cote D’Ivoire ◽  
Côte D'ivoire ◽  
Oral Hygiene Habits

Abstract Background Despite the proven links between oral health status and adverse pregnancy outcomes, oral examination is not systematically integrated into prenatal examinations in Côte d’Ivoire. In addition, there are no prevention messages specifically targeted at pregnant women. Objective: To assess the oral health of pregnant women in Côte d’Ivoire. Methods A cross-sectional survey was conducted at the Maternal and Child Health Department of the National Public Health Institute in Abidjan. The data collected were: age, education level, marital status, source of income, trimester of pregnancy, gestational age, oral hygiene habits and the fact that they whether or not received oral health information. A clinical examination was conducted to assess oral hygiene (OHIS index), periodontal condition (CPI index), dental condition (DMFT index), as well as the presence of epulis, erosion or dental mobility. Frequencies and counts were calculated for the different variables in the study. Results A total of 207 women were observed. The age range was 15 to 44 years with 14.0% under 19 years old. The majority were in couple (76.8%), multi-gesture (77.3%), and more than half had no education (52.2%) or source of income (56.0%); 50.7% snacked between meals and 33.3% had vomiting. They brushed their teeth at least twice a day (70.0%) and had not changed their oral hygiene habits (77.3%) during this pregnancy. Only 3.4% had information on oral health conditions during pregnancy. The frequency of caries was 75.4%, dental erosions 13.0%, gingivitis 57.0%, periodontitis 6.8% and epulis 3.4%. Conclusions The results suggest the integration of systematic dental consultation into prenatal consultations in order permit the sensitization of these women, screening and management of their oral conditions. Key messages Oral diseases of pregnant women are a reality without their knowledge in Côte d’Ivoire. A systematic dental visit is essential during prenatal consultations in Côte d’Ivoire.

scholarly journals Obtaining informed consent from HIV-infected pregnant women, Abidjan, Côte d'Ivoire

AIDS ◽  
2004 ◽  
Vol 18 (10) ◽  
pp. 1486-1488 ◽  
Author(s):  
Koumavi Didier Ekouevi ◽  
Renaud Becquet ◽  
Ida Viho ◽  
Laurence Bequet ◽  
François Dabis ◽  
...  
Keyword(s):  
Informed Consent ◽  
Pregnant Women ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Cote D’Ivoire ◽  
Côte D'ivoire

scholarly journals Prevalence of Schistosoma mono- and co-infections with multiple common parasites and associated risk factors and morbidity profile among adults in the Taabo health and demographic surveillance system, South-Central Côte d’Ivoire

2022 ◽  
Vol 11 (1) ◽  
Author(s):  
Fidèle K. Bassa ◽  
Ikenna C. Eze ◽  
Rufin K. Assaré ◽  
Clémence Essé ◽  
Siaka Koné ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Public Health Problem ◽  
Urine Samples ◽  
Health Examination ◽  
Important Public Health Problem ◽  
Cote D’Ivoire ◽  
South Central ◽  
Côte D'ivoire

Abstract Background Schistosomiasis remains an important public health problem, also among adults, and infected individuals not treated serve as a reservoir for continued transmission. Despite this fact, evidence on the epidemiology of schistosomiasis in adults in Côte d’Ivoire is scanty. This study aimed to determine the prevalence and risk factors of Schistosoma infection and co-infection with other helminth species and Plasmodium among adults in the Taabo region in the south-central part of Côte d’Ivoire. Methods A cross-sectional survey was carried out in April and May 2017 in the frame of the “Côte d’Ivoire Dual Burden of Disease Study” (CoDuBu). A total of 901 randomly selected individuals, aged 18–90 years, provided blood, stool and urine samples for the diagnosis of malaria and helminth infections. Stool samples were subjected to the Kato-Katz technique for detection of Schistosoma mansoni and soil-transmitted helminth eggs, while urine samples were examined for eggs of Schistosoma haematobium and circulating cathodic antigen of S. mansoni. Risk factors and morbidity profiles were assessed using health examination and questionnaires. Multinomial logistic regressions were employed to identify risk factors and morbidity patterns associated with S. mansoni mono- and co-infections. Results The prevalence of S. mansoni and S. haematobium was 23.2% and 1.0%, respectively. Most S. mansoni were mono-infections (81.3%). Independent determinants of S. mansoni infection were young age, low socioeconomic status (mono- and co-infection) and poor hygiene practices (co-infection) (P < 0.05). S. mansoni infection was independently associated with higher pain and symptom scores (mono-infection), poor self-rated health and low healthcare use (co-infection) (P < 0.05). Conclusions This study showed that adults represent a substantial reservoir of S. mansoni. To sustain schistosomiasis control and improve people’s wellbeing, it is important to expand preventive chemotherapy from school-aged children to adults, coupled with hygiene and health education.

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