scholarly journals Isoniazid-induced gynaecomastia: report of a paediatric case and review of literature

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sarah Wing Yiu Poon ◽  
Ka Ka Siu ◽  
Anita Man Ching Tsang
Keyword(s):  
Case Report ◽  
Paediatric Population ◽  
Adult Males ◽  
Common Condition ◽  
Review Of Literature ◽  
Case Presentation ◽  
Paediatric Case ◽  
Prepubertal Boys ◽  
Prompt Diagnosis ◽  
New Onset

Abstract Background Gynaecomastia is a fairly common condition in puberty but is rare in prepubertal boys. While it is necessary to exclude possible endocrinopathay in prepubertal gynaecomastia, medication is an important and potentially reversible cause to consider in new onset gynaecomastia. Isoniazid-induced gynaecomastia has been reported in adult males, but none was reported in the paediatric population and general paediatricians may not be aware of this uncommon side effect. Case presentation We hereby report a 11-year-old prepubertal boy who developed gynaecomastia while taking anti-tuberculosis drugs. Investigations excluded endocrinopathies. Gynaecomastia subsided 8 weeks after stopping isoniazid. Conclusion This case is the first paediatric case report describing the association of gynaecomastia with isoniazid use. It is important for general paediatricians to recognize this entity, as prompt diagnosis and cessation of the offending drug can lead to resolution of the problem.

scholarly journals Case report: a 5-year-old with new onset nephrotic syndrome in the setting of COVID-19 infection

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kelsi M. Morgan ◽  
Peace D. Imani
Keyword(s):  
Nephrotic Syndrome ◽  
Case Report ◽  
Pediatric Patient ◽  
Corticosteroid Therapy ◽  
Clinical Remission ◽  
Laboratory Findings ◽  
Case Presentation ◽  
The Third ◽  
First Case ◽  
New Onset

Abstract Background This is a case report of an asymptomatic SARS-CoV-2 infection associated with new-onset nephrotic syndrome in a pediatric patient. This is the third case of new-onset nephrotic syndrome in children associated with SARS-CoV-2 infection, but is the first case report describing a new-onset nephrotic syndrome presentation in a patient who had asymptomatic COVID-19 infection. Case presentation This is a case of a previously healthy 5 year old female who presented with new-onset nephrotic syndrome in the setting of an asymptomatic COVID-19 infection. She presented with progressive edema, and laboratory findings were significant for proteinuria and hypercholesterolemia. She was treated with albumin, diuretics, and corticosteroid therapy, and achieved clinical remission of her nephrotic syndrome within 3 weeks of treatment. Though she was at risk of hypercoagulability due to her COVID-19 infection and nephrotic syndrome, she was not treated with anticoagulation, and did not develop any thrombotic events. Conclusions Our case report indicates that SARS-CoV-2 infection could be a trigger for nephrotic syndrome, even in the absence of overt COVID-19 symptoms.

scholarly journals Clinical features of acute kidney injury in Coronavirus disease 2019—A case report with review of literature

2020 ◽  
Author(s):  
Hai Yuan ◽  
Xiaohan Lu ◽  
E Guo ◽  
Fengqi Hu ◽  
Zhao Gao
Keyword(s):  
Acute Kidney Injury ◽  
Case Report ◽  
Kidney Function ◽  
Kidney Injury ◽  
Hubei Province ◽  
Review Of Literature ◽  
Case Presentation ◽  
High Incidence ◽  
Careful Management ◽  
High Incidence Area

Abstract Background: In December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, Hubei province, China. We surveyed 91 patients who were diagnosis as coronavirus disease 2019 (COVID-19) in Xiangyang, Hubei province. And we found the incident of acute kidney injury (AKI) was 3.29% (3/91), which was higher than in the whole country but similar in Hubei province.Case presentation: We describe a case of 58-year-old man who was diagnosis as AKI stage 3 and non-oliguria AKI in the SARS-CoV-2 infection. After antiviral and other supporting treatment, his kidney function improved and he was transferred to normal ward.Conclusions: This case illustrated that careful management and strict monitoring of kidney function should be employed in COVID-19 patients especially in high incidence area of COVID-19.

AN UNUSUAL CASE OF NEW ONSET NEPHROPATHY IN A PATIENT OF PSORIASIS: CASE REPORT AND REVIEW OF LITERATURE

2021 ◽  
pp. 13-14
Author(s):  
VPS Punia ◽  
Apoorva Shetty ◽  
Prashant Prashant ◽  
Akash Bharti ◽  
Praveen Raman Mishra ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Case Report ◽  
Male Patient ◽  
Renal Damage ◽  
Unusual Case ◽  
Review Of Literature ◽  
Immune Mediated ◽  
Different Types ◽  
Glomerular Lesions ◽  
New Onset

Psoriasis is known to cause chronic inammatory disorder of the skin through an immune mediated mechanism, it may be complicated by different types of glomerular lesions. Three different mechanisms have been implicated by which psoriasis can cause renal damage: immune-mediated renal damage, drug-related renal damage and chronic renal damage. This report presents a case of 35 years old male patient with extensive psoriasis, who presented to our hospital with nephrotic syndrome

A Case Report on the Surgical Management of Subhepatic Perforated Appendicitis: A Rare Presentation

2020 ◽  
Author(s):  
Mumin Hakim ◽  
Rania Mostafa ◽  
Mohammed Al Shehri ◽  
Sherif Sharawy
Keyword(s):  
Case Report ◽  
Acute Appendicitis ◽  
Female Patient ◽  
Surgical Management ◽  
Perforated Appendicitis ◽  
Exploratory Laparotomy ◽  
Atypical Presentation ◽  
Review Of Literature ◽  
Rare Presentation ◽  
Case Presentation

Abstract Background: Subhepatic appendicitis is an exceedingly rare presentation accounting for 0.01% of Acute appendicitis. It is of prime importance to be aware of various variants and thereby managing such challenging cases accordingly.Case presentation: We present a middle-aged female patient with subhepatic perforated appendicitis and peritonitis who underwent an exploratory laparotomy and appendectomy.Conclusions: Surgical management of such patients is challenging due to an atypical presentation. The surgical management of such patients is discussed with a brief review of literature.

scholarly journals An unusual combined parotideal and neck abscess - Case report

2016 ◽  
Vol 6 (24) ◽  
pp. 229-231
Author(s):  
Ricardo de Hoyos ◽  
Michele Loglisci ◽  
Hugo Anibal Rodriguez ◽  
Desiderio Passali
Keyword(s):  
Antibiotic Resistance ◽  
Case Report ◽  
Paediatric Population ◽  
Rare Finding ◽  
Neck Abscess ◽  
Paediatric Case ◽  
Cervical Swelling

Abstract Cervical and parotideal abscess is a rare finding in all populations and even more so in the paediatric population. The antibiotic resistance of the bacteria that cause these diseases can make it very dangerous. We present a paediatric case in which there is a combined left-cervical and parotideal abscess in a female 3-month-old baby who presented fever, pain and cervical swelling.

scholarly journals New Onset Focal Seizure Following COVID-19 Vaccination: Case Report

2021 ◽  
Author(s):  
Chun Seng Phua ◽  
Shalini Bhaskar ◽  
Azman Ali Raymond
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Focal Seizure ◽  
Seizure Threshold ◽  
Hippocampal Atrophy ◽  
Case Presentation ◽  
Mri Brain ◽  
Focal Seizures ◽  
Patient’S History ◽  
New Onset

Abstract IntroductionAs more novel COVID-19 vaccines are being rolled out in a frantic pace globally, any complication that might be related to COVID-19 vaccines should be highlighted, especially since COVID-19 vaccines are relatively new, and side effects may yet to be fully elucidated. We report a case of a healthy 18-year-old male who presented with new onset focal seizures 5 days after receiving 1st dose of Oxford/AstraZeneca COVID-19 vaccine. Case PresentationThe patient was treated with intravenous phenytoin and oral levetiracetam 250mg twice daily with no further events. There was no documented fever. CT venogram and EEG were unremarkable. MRI brain revealed generalised atrophy including mild bilateral hippocampal atrophy with no evidence of sclerosis. There was no predilection for seizures identified from the patient’s history. The patient was discharged the following day on levetiracetam and advised to proceed with the 2nd dose of Oxford/AstraZeneca COVID-19 vaccination in 3 months’ time.ConclusionSeizures following COVID-19 vaccination have only been reported in a handful of cases. COVID-19 vaccination could lower seizure threshold, or unmask an underlying predisposition for epilepsy. As most COVID-19 vaccines worldwide are given in 2 doses, clinicians should consider maintaining patients on anti-seizure drugs if vaccination was thought to be a provoking factor.

scholarly journals Percutaneous Balloon Pericardiotomy (PBP) Revisited: A Case Report and Review of Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Raed Aqel ◽  
Muawiyah Elqadi ◽  
Ahmad Hammouri ◽  
Mohammad S. Alqadi
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Stage Iv ◽  
Shortness Of Breath ◽  
Review Of Literature ◽  
Pericardial Window ◽  
Severe Respiratory Distress ◽  
Case Presentation ◽  
Percutaneous Balloon ◽  
Recurrent Pericardial Effusion

Background. A Percutaneous Balloon Pericardiotomy (PBP) procedure is a reemerging nonsurgical technique that helps in preventing the reaccumulation of pericardial effusion. It is done percutaneously without general anaesthesia. It has been proved to be effective in alleviating and preventing recurrent pericardial effusion. Case Presentation. We reported a 52-year-old male with stage IV adenocarcinoma causing recurrent pericardial effusion. The patient experienced a worsening shortness of breath. A surgical pericardial window was denied by the surgery team secondary to severe respiratory distress; subsequently, the patient underwent Percutaneous Balloon Pericardiotomy. Conclusion. Percutaneous Balloon Pericardiotomy is efficacious and safe when done by well-trained physicians. We think it should be considered as a preferred treatment modality in most sicker patients with recurrent pericardial effusion.

Atypical Congenital Triangular Alopecia (Brauer Nevus): Case Report and Review of Literature in Occipital and Mid-Frontal Localizations

2021 ◽  
pp. 1-6
Author(s):  
Ana Rodríguez-Villa Lario ◽  
Juan Ferrando ◽  
Óscar M. Moreno-Arrones ◽  
Alba Gómez-Zubiaur
Keyword(s):  
Case Report ◽  
Alopecia Areata ◽  
Frontal Region ◽  
Atypical Presentation ◽  
Review Of Literature ◽  
Case Presentation ◽  
Male Sex

<b><i>Introduction:</i></b> Brauer nevus, also known as congenital triangular alopecia (CTA) is a localized alopecia that rarely affects the occipital or mid-frontal region. CTA is a localized follicular hypoplasia, commonly misdiagnosed as alopecia areata. Although named congenital, onset in adulthood is possible. <b><i>Case Presentation:</i></b> We present a review of literature of eighteen atypical locations, providing 4 new cases to the 9 previously published, with particular attention to trichoscopy and histopathological descriptions in this exceptional presentation forms. <b><i>Discussion:</i></b> Occipital and mid-frontal Brauer nevus are unusual findings with very few cases reported so far. Because of its rarity and atypical presentation, it can often lead to a misdiagnosis. A higher incidence in the male sex stands clear in these locations. Detection at birth is slightly more frequent than in the classical CTA. Histopathological and trichoscopy findings do not differ from the classical entity, although white or hypopigmented hairs do not seem to be an item present in the mid-frontal forms.

scholarly journals Severe Generalized Bullous Fixed Drug Eruption Treated with Cyclosporine: A Case Report and Literature Review

2021 ◽  
pp. 154-163
Author(s):  
Hailey C. Barootes ◽  
Erin R. Peebles ◽  
Doreen Matsui ◽  
Michael Rieder ◽  
Awatif Abuzgaia ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cyclosporine A ◽  
Drug Eruption ◽  
Paediatric Population ◽  
Fixed Drug Eruption ◽  
Drug Eruptions ◽  
Fixed Drug ◽  
Paediatric Case ◽  
Oral Ibuprofen

Generalized bullous fixed drug eruptions (GBFDEs) are rare in the paediatric population. We present the case of a 7-year-old girl with GBFDE believed to be secondary to oral ibuprofen, who experienced rapid resolution of lesions and cessation of blistering with a 3-week course of oral cyclosporine. To the best of our knowledge, this is the first report of a paediatric case of GBFDE treated with cyclosporine. In our report, we review published cases of GBFDE in children, and all adult cases managed with cyclosporine.

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