scholarly journals Trypanocidal activity of ethanolic extracts of Commiphora swynnertonii Burtt on Trypanosoma congolense

Author(s):  
Yakob P. Nagagi ◽  
Richard S. Silayo ◽  
Eliningaya J. Kweka
2016 ◽  
Vol 60 (7) ◽  
pp. 4391-4393 ◽  
Author(s):  
Keisuke Suganuma ◽  
Albertus Eka Yudistira Sarwono ◽  
Shinya Mitsuhashi ◽  
Marcin Jąkalski ◽  
Tadashi Okada ◽  
...  

ABSTRACTThis study aimed to evaluate the trypanocidal activity of mycophenolic acid (MPA) and its derivatives forTrypanosoma congolense. The proliferation ofT. congolensewas completely inhibited by adding <1 μM MPA and its derivatives. In addition, the IMP dehydrogenase inT. congolensewas molecularly characterized as the target of these compounds. The results suggest that MPA and its derivatives have the potential to be new candidates as novel trypanocidal drugs.


Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
WR Cunha ◽  
FM Dos Santos ◽  
JA Peixoto ◽  
RCS Veneziani ◽  
AEM Crotti ◽  
...  

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
M Bival Tefan ◽  
D Jelic ◽  
S Vladimir-Kneevic ◽  
M Trzun ◽  
K Frka Boric ◽  
...  

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
M Niculae ◽  
CD Sandru ◽  
E Pall ◽  
S Popescu ◽  
L Stan ◽  
...  

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
RF Abdel-Rahman ◽  
H Yusufoglu ◽  
GA Soliman ◽  
I Tatli-Çankaya

Planta Medica ◽  
2006 ◽  
Vol 72 (11) ◽  
Author(s):  
B Nickavar ◽  
FS Abolhasani ◽  
M Kamalinejad ◽  
MR Reza Khani ◽  
F Mojab

2018 ◽  
Vol 24 (2) ◽  
Author(s):  
GITA MISHRA ◽  
HEMESHWER KUMAR CHANDRA ◽  
NISHA SAHU ◽  
SATENDRA KUMAR NIRALA ◽  
MONIKA BHADAURIA

Pergularia daemia belongs to the family Asclepiadaceae, known to have anticancer, anti-inflammatory activity. Aim of the present study was to evaluate qualitative and quantitative phytochemical and antioxidant properties of ethanolic extracts of leaf, stem and root parts of P. daemia . Preliminary phytochemical analysis and in vitro antioxidant properties were evaluated by standard methods. The qualitative phytochemical analysis of P. daemia showed presence of flavonoids, tannins, alkaloid, phytosterol, carbohydrate, phenol, saponin, glycosides, terpenoids, steroids proteins and reducing sugars. Quantitative analysis showed polyphenol, flavonoid, flavonone, flavone and flavonol in P. daemia leaves, stem and root in considerable quantity. The in vitro antioxidant activity of P. daemia clearly demonstrated that leaf, stem and root parts have prominent antioxidant properties and was effective in scavenging free radicals.


Sign in / Sign up

Export Citation Format

Share Document