scholarly journals Characterization of burn wound healing gel prepared from human amniotic membrane and Aloe vera extract

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Md Shaifur Rahman ◽  
Rashedul Islam ◽  
Md Masud Rana ◽  
Lucas-Sebastian Spitzhorn ◽  
Mohammad Shahedur Rahman ◽  
...  
Keyword(s):  
Wound Healing ◽  
Amniotic Membrane ◽  
Aloe Vera ◽  
Human Amniotic Membrane ◽  
Burn Wound ◽  
Burn Wound Healing

Assortment of human amniotic membrane and curcumin: a potential therapeutic strategy for burn wound healing

2020 ◽  
Vol 15 ◽  
Author(s):  
Ayesha Siddika ◽  
Md. Arifuzzaman ◽  
Liakat Hossain ◽  
Md. Hasib Adnan ◽  
Farzana Diba ◽  
...  
Keyword(s):  
Wound Healing ◽  
Amniotic Membrane ◽  
Therapeutic Strategy ◽  
Burn Injury ◽  
Cost Effective ◽  
Human Amniotic Membrane ◽  
Microbial Infection ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Potential Source

: Burn wound associated injury management is one of the major unresolved clinical concerns. Most of the drugs and dressing materials found in the market cause dose escalation and even exert side effects. Besides, a severe burn injury is susceptible to microbial infection that leads to prolonged hospital stay which ultimately causes a financial crisis to the victims. To get rid of this problem, researchers are being interested in developing such materials that are cost-effective, easily available and accelerate faster healing. Human amniotic membrane (AM) and various herbal extracts like curcumin are a potential source of burn wound healing. AM has various healing properties and is being used as a best burn wound dressing material for centuries. Similarly, curcumin has been proven as faster dressing material for the treatment of burn injury. Since both AM and curcumin are a potential source of burn and wound healing, if a gel/agent could be formulated by mixing these two things, this combination may be a potential therapeutic strategy to treat burn wound healing.

The efficacy of aloe vera used for burn wound healing: A systematic review

Burns ◽  
2007 ◽  
Vol 33 (6) ◽  
pp. 713-718 ◽  
Author(s):  
Ratree Maenthaisong ◽  
Nathorn Chaiyakunapruk ◽  
Surachet Niruntraporn ◽  
Chuenjid Kongkaew
Keyword(s):  
Systematic Review ◽  
Wound Healing ◽  
Aloe Vera ◽  
Burn Wound ◽  
Burn Wound Healing

Preparation and characterization of human keratinocyte–fibroblast cell sheets constructed using PNIAM-co-AM grafted surfaces for burn wound healing

2020 ◽  
Vol 31 (12) ◽  
Author(s):  
Kanokaon Benchaprathanphorn ◽  
Phongphot Sakulaue ◽  
Wanwipa Siriwatwechakul ◽  
Pornprom Muangman ◽  
Kusuma Chinaroonchai ◽  
...  
Keyword(s):  
Wound Healing ◽  
Fibroblast Cell ◽  
Burn Wound ◽  
Cell Sheets ◽  
Burn Wound Healing ◽  
Human Keratinocyte

ALOE VERA AND BURN WOUND HEALING

1989 ◽  
Vol 83 (6) ◽  
pp. 1075 ◽  
Author(s):  
Teddy Kaufman ◽  
A. R. Newman ◽  
M. R. Wexler
Keyword(s):  
Wound Healing ◽  
Aloe Vera ◽  
Burn Wound ◽  
Burn Wound Healing

The Safety and Efficacy of Mupirocin Topical Spray for Burn Wound Healing in A Rat Model

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Sritharadol Rutthapol ◽  
Chunhachaichana Charisopon ◽  
Kumlungmak Sukanjana ◽  
Buatong Wilaiporn ◽  
Dechraksa Janwit ◽  
...  
Keyword(s):  
Wound Healing ◽  
Matrix Metalloproteinase ◽  
Rat Model ◽  
Transforming Growth Factor ◽  
Immunohistochemical Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Burn Wound ◽  
Safety And Efficacy ◽  
Burn Wound Healing ◽  
Tgf Β1

ABSTRACT This study evaluated the effect of mupirocin topical spray on burn wound healing in a rat model. Fifteen male Sprague Dawley rats were used to create full-thickness burns on the rat dorsum using a cylindrical stainless steel rod. The rats were topically treated with normal saline solution (NSS), mupirocin spray, ointment, and solution. The wound size and morphological evaluation were investigated by photographs and clinical criterions for wound healing. The histology was observed by hematoxylin and eosin (HandE) staining assay. The immunohistochemical study was evaluated by detection of transforming growth factor-beta 1 (TGF-β1), and the ratio of matrix metalloproteinase-9 to the tissue inhibitor of matrix metalloproteinase-1 (MMP-9/TIMP-1) was quantified using the enzyme-linked immunosorbent assay (ELISA) assay. A complete healing was observed at 28 days in all treatments. Mupirocin formulations accelerated the wound healing faster than NSS in size. However, the clinical criteria indicated a desirable skin appearance in the mupirocin spray and ointment treated groups. The histological evaluations showed no differences between the treatments while the immunohistochemical study revealed that all treatments reduced the level of TGF-β1 over time, particularly on day 28 in the mupirocin spray and ointment treated groups. The MMP-9/TIMP-1 ratio was significantly lower in the mupirocin spray and ointment treated groups than in the NSS and mupirocin solution groups. This study shows the safety and efficacy in the use of mupirocin topical spray. The topical mupirocin spray is an alternative suitable for development as a human topical anti-infective and wound protection spray.

scholarly journals Validity of thermography for measuring burn wound healing potential

2019 ◽  
Vol 28 (3) ◽  
pp. 347-354 ◽  
Author(s):  
Michelle E. Carrière ◽  
Louise E. M. Haas ◽  
Anouk Pijpe ◽  
Annebeth Meij‐de Vries ◽  
Kim L. M. Gardien ◽  
...  
Keyword(s):  
Wound Healing ◽  
Burn Wound ◽  
Burn Wound Healing
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