Targeted enzyme prodrug therapy for metastatic prostate cancer – a comparative study of L-methioninase, purine nucleoside phosphorylase, and cytosine deaminase

Cytosine Deaminase ◽

Purine Nucleoside ◽

Enzyme Prodrug Therapy ◽

Nucleoside Phosphorylase

Purine nucleoside phosphorylase and fludarabine phosphate gene-directed enzyme prodrug therapy suppresses primary tumour growth and pseudo-metastases in a mouse model of prostate cancer

The Journal of Gene Medicine ◽

10.1002/jgm.629 ◽

2004 ◽

Vol 6 (12) ◽

pp. 1343-1357 ◽

Cited By ~ 24

Author(s):

Rosetta Martiniello-Wilks ◽

Xiao Yang Wang ◽

Dale J. Voeks ◽

Allison Dane ◽

Jan M. Shaw ◽

...

Keyword(s):

Prostate Cancer ◽

Mouse Model ◽

Tumour Growth ◽

Primary Tumour ◽

Purine Nucleoside ◽

Enzyme Prodrug Therapy ◽

Fludarabine Phosphate ◽

Primary Tumour Growth

Erratum: Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy

The Journal of Gene Medicine ◽

10.1002/jgm.2617 ◽

2012 ◽

Vol 14 (3) ◽

pp. 217-217

Author(s):

Xinhua Xie ◽

Jiaoli Guo ◽

Yanan Kong ◽

Gene Xianquan Xie ◽

Laishen Li ◽

...

Keyword(s):

Prostate Cancer ◽

Escherichia Coli ◽

Cancer Therapy ◽

Purine Nucleoside ◽

Prostate Cancer Therapy ◽

Targeted Expression

18. Comparison of Antitumor Activity of Cytosine Deaminase::Uracil Phosphoribosyl Transferase (CD::UPRT) and Purine Nucleoside Phosphorylase (PNP) Suicide Genes Using Replicative but Non-Disseminative Adenovirus Vectors

Molecular Therapy ◽

10.1016/j.ymthe.2006.08.029 ◽

2006 ◽

Vol 13 ◽

pp. S8

Author(s):

Jairo Jaime ◽

Nadine Jabbour ◽

William Parker ◽

Eric Sorscher ◽

Josephine Nalbantoglu ◽

...

Keyword(s):

Antitumor Activity ◽

Cytosine Deaminase ◽

Purine Nucleoside ◽

Suicide Genes ◽

Phosphoribosyl Transferase ◽

Adenovirus Vectors

Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models

Gene Therapy ◽

10.1038/sj.gt.3301698 ◽

2002 ◽

Vol 9 (12) ◽

pp. 759-768 ◽

Cited By ~ 44

Author(s):

D Voeks ◽

R Martiniello-Wilks ◽

V Madden ◽

K Smith ◽

E Bennetts ◽

...

Keyword(s):

Prostate Cancer ◽

Gene Therapy ◽

Mouse Models ◽

Purine Nucleoside ◽

Nucleoside Phosphorylase

1199. Novel Gene Therapy for Prostate Cancer: In Vivo-Targeted Expression of the E. Coli Purine Nucleoside Phosphorylase Gene by Adenoviral Delivery

Molecular Therapy ◽

10.1016/s1525-0016(16)44029-3 ◽

2002 ◽

Vol 5 (5) ◽

pp. S389-S390

Keyword(s):

Prostate Cancer ◽

Gene Therapy ◽

Purine Nucleoside ◽

E Coli ◽

Novel Gene ◽

Adenoviral Delivery ◽

Targeted Expression

Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer

British Journal of Cancer ◽

10.1038/bjc.2011.462 ◽

2011 ◽

Vol 106 (2) ◽

pp. 405-413 ◽

Cited By ~ 140

Author(s):

S Kojima ◽

T Chiyomaru ◽

K Kawakami ◽

H Yoshino ◽

H Enokida ◽

...

Keyword(s):

Prostate Cancer ◽

Purine Nucleoside ◽

Tumour Suppressors ◽

Oncogenic Function

Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy

The Journal of Gene Medicine ◽

10.1002/jgm.1620 ◽

2011 ◽

Vol 13 (12) ◽

pp. 680-691 ◽

Cited By ~ 13

Author(s):

Xinhua Xie ◽

Jiaoli Guo ◽

Yanan Kong ◽

Gene Xianquan Xie ◽

Laishen Li ◽

...

Keyword(s):

Prostate Cancer ◽

Escherichia Coli ◽

Cancer Therapy ◽

Purine Nucleoside ◽

Prostate Cancer Therapy ◽

Targeted Expression

842 Tumor suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer

European Urology Supplements ◽

10.1016/s1569-9056(12)60839-2 ◽

2012 ◽

Vol 11 (1) ◽

pp. e842-e842a

Author(s):

S. Kojima ◽

T. Chiyomaru ◽

K. Kawakami ◽

H. Yoshino ◽

H. Enokida ◽

...

Keyword(s):

Prostate Cancer ◽

Tumor Suppressors ◽

Purine Nucleoside ◽

Oncogenic Function

Purine Nucleoside Phosphorylase Targeted by Annexin V to Breast Cancer Vasculature for Enzyme Prodrug Therapy

PLoS ONE ◽

10.1371/journal.pone.0076403 ◽

2013 ◽

Vol 8 (10) ◽

pp. e76403 ◽

Cited By ~ 10

Author(s):

John J. Krais ◽

Olivier De Crescenzo ◽

Roger G. Harrison

Keyword(s):

Breast Cancer ◽

Annexin V ◽

Purine Nucleoside ◽

Enzyme Prodrug Therapy ◽

Nucleoside Phosphorylase

487 IDENTIFICATION OF PURINE NUCLEOSIDE PHOSPHORYLASE (PNP) AS A NOVEL TARGET OF TUMOR SUPPRESSORS MIR-1 AND MIR-133A IN PROSTATE CANCER

The Journal of Urology ◽

10.1016/j.juro.2012.02.556 ◽

2012 ◽

Vol 187 (4S) ◽

Author(s):

Satoko Kojima ◽

Takeshi Chiyomaru ◽

Hirofumi Yoshino ◽

Hideki Enokida ◽

Nijiro Nohata ◽

...

Keyword(s):

Prostate Cancer ◽

Tumor Suppressors ◽

Purine Nucleoside ◽

Novel Target