Untreated depressive symptoms significantly worsen quality of life in old age and may lead to the misdiagnosis of dementia: a cross-sectional study

Abstract Background Several studies demonstrated the role of depressive mood and cognitive impairment in the background of elevated mortality and decreased Quality of Life (QoL) in old age. Our aim was to assess depressive and cognitive symptoms among older people in order to determine if those are recognized and treated or not, to elucidate the association between them and to investigate their impact on QoL. Methods In the framework of the ICT4Life project self-administered questionnaires and clinical screening tools were used to assess QoL, depressive symptoms and cognitive functions of 60 older persons over the age of 65. Results Males found to be depressed (53.8 vs. 40.4%) and cognitively declined (53.8 vs. 48.9%) more frequently; and had higher scores on the depression (6.85 vs. 5.32) and lower on the QoL (47.38 vs. 50.19) scales. Depressed older persons had lower cognitive levels (24.39 vs. 21.52) and their QoL was significantly poorer (53.97 vs. 43.85) than that of the non-depressed subjects. Depressive symptoms were detected in almost half of the older adults (43.9%), and the majority (80.77%) did not receive antidepressant medication. Conclusions Depressive and cognitive symptoms found to be common among older people, but were not recognized and treated in most cases. Close correlation between depression and cognitive impairment was also confirmed, as well as the key role of depression in the background of pseudo-dementia and QoL decline. Early recognition of depressive symptoms is important not only to treat the underlying mood disorder, but also to improve QoL of older persons.

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Untreated Depressive Symptoms Significantly Worsen Quality of Life of the Elderly and may Lead to the Misdiagnosis of Dementia: A Cross-Sectional Study

10.21203/rs.3.rs-32991/v1 ◽

2020 ◽

Author(s):

Viktor Voros ◽

Sandor Fekete ◽

Tamas Tenyi ◽

Zoltan Rihmer ◽

Ilona Szili ◽

...

Keyword(s):

Quality Of Life ◽

Cognitive Impairment ◽

Depressive Symptoms ◽

Depressive Disorders ◽

Early Recognition ◽

The Elderly ◽

Screening Tools ◽

Adequate Treatment

Abstract Background: Several studies demonstrated the role of depressive mood and cognitive impairment in the background of elevated mortality and decreased Quality of Life (QoL) of the elderly.Methods: In the framework of the ICT4Life project self-administered questionnaires and clinical screening tools were used to assess QoL, depressive symptoms and cognitive functions of 60 elderly over the age of 65.Results: Males found to be depressed and cognitively declined more frequently; and had higher scores on the depression and lower on the QoL scales. Depressed elderly had lower cognitive levels and their QoL was significantly poorer than that of the non-depressed subjects. Depressive disorders were detected in a quarter of the elderly, and the majority of them did not receive adequate antidepressant medication.Conclusions: Close correlation between depression and cognitive impairment was confirmed, as well as the key role of depression in the background of QoL decline. Results also highlighted the problems of recognition and adequate treatment of depression and cognitive decline in elderly, which can be further complicated by the common symptoms of depressive pseudo-dementia. Early recognition of depressive symptoms is important not only to treat the underlying mood disorder, but also to improve QoL of the elderly.

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Multimorbidity and Health-Related Quality of Life in Old Age: Role of Functional Dependence and Depressive Symptoms

Journal of the American Medical Directors Association ◽

10.1016/j.jamda.2019.02.024 ◽

2019 ◽

Vol 20 (9) ◽

pp. 1143-1149 ◽

Cited By ~ 5

Author(s):

Rui She ◽

Zhongrui Yan ◽

Hui Jiang ◽

Davide L. Vetrano ◽

Joseph T.F. Lau ◽

...

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Old Age ◽

Functional Dependence ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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The Relationship Between Mild Cognitive Impairment and Mood in Older People

10.31237/osf.io/pu7sg ◽

2018 ◽

Author(s):

Jennifer Yates

Keyword(s):

Quality Of Life ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Older People ◽

Empirical Work ◽

Ageing Study ◽

Using Data ◽

The Relationship

Mild cognitive impairment (MCI) has received increasing attention since the early 1990s. However, considerable controversy exists over exactly how the concept of MCI is defined and measured, and the implications of assigning or receiving a diagnosis of MCI. There is evidence of a link between MCI and mood, but empirical work remains conflicted and inconclusive. The first chapter provides an overview of the MCI concept and highlights some of the issues surrounding its definition. Chapter 2 provides a detailed description of the methodology and background to the empirical work presented in Chapters 4-6. A systematic review of the literature forms the third chapter of this thesis and establishes the need for further study into the relationship between MCI and mood. Chapter 4 makes use of data from the first Cognitive Function and Ageing Study (MRC-CFAS I) to investigate the role of subjective memory complaints (SMC) in the relationship between MCI and mood over a two year period. The results indicated that SMC may be related more strongly to mood than to objective cognitive performance, which raises questions about whether SMC should be included as a criterion in the MCI definition. Chapter 5 clarifies these findings using data from a contemporary cohort in the Cognitive Function and Ageing Study Wales (CFAS Wales). Chapter 6 investigates the role of health in the relationship between MCI and mood, again using data from CFAS Wales. The findings suggest that health problems constitute a risk factor for developing depression and anxiety, which may in turn affect cognitive functioning. This presents a useful opportunity for intervention to improve the quality of life for older people by improving their physical health, or improving the management of long-term conditions. Social networks were investigated as an influential factor in the relationship between MCI and mood, using data from CFAS Wales. Whilst increases in social network size were associated with fewer mood problems and increased cognitive functioning, they did not moderate the relationship between the two. However, this finding still showed that having more social contacts is beneficial and important to the quality of life of older people. The last chapter presents a discussion of the findings in relation to each of the research questions outlined in Chapter 1. The chapter also includes a commentary on the methodological considerations that were faced when developing this thesis, the implications of the findings and directions for future research.

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Is Tai Chi an effective intervention for enhancing health‐related quality of life in older people with mild cognitive impairment? An interventional study

International Journal of Older People Nursing ◽

10.1111/opn.12400 ◽

2021 ◽

Author(s):

Mei‐yi Siu ◽

Diana T. F. Lee

Keyword(s):

Quality Of Life ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Older People ◽

Tai Chi ◽

Health Related Quality ◽

Interventional Study ◽

Related Quality ◽

Health Related

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Sleep Quality and Health-Related Quality of Life in Older People With Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer Disease

The Journal of Nervous and Mental Disease ◽

10.1097/nmd.0000000000001137 ◽

2020 ◽

Vol 208 (5) ◽

pp. 387-396 ◽

Cited By ~ 1

Author(s):

Minmin Leng ◽

Huiru Yin ◽

Ping Zhang ◽

Yong Jia ◽

Mingyue Hu ◽

...

Keyword(s):

Quality Of Life ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Alzheimer Disease ◽

Older People ◽

Subjective Cognitive Decline ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Quality of life in individuals with attenuated psychotic symptoms: Possible role of anxiety, depressive symptoms, and socio-cognitive impairments

Psychiatry Research ◽

10.1016/j.psychres.2017.08.024 ◽

2017 ◽

Vol 257 ◽

pp. 431-437 ◽

Cited By ~ 12

Author(s):

Tsutomu Takahashi ◽

Yuko Higuchi ◽

Yuko Komori ◽

Shimako Nishiyama ◽

Mihoko Nakamura ◽

...

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Cognitive Impairments ◽

Psychotic Symptoms

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What Does Imaging Add to the Management of Alzheimer's Disease?

CNS Spectrums ◽

10.1017/s1092852900024779 ◽

2004 ◽

Vol 9 (S5) ◽

pp. 20-23 ◽

Cited By ~ 4

Author(s):

Gary W. Small

Keyword(s):

Quality Of Life ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Imaging Techniques ◽

Screening Tools ◽

Surrogate Markers ◽

Genetic Disposition ◽

Number Of Patients

AbstractThe prevalence of Alzheimer's disease (AD) and dementia continues to rise. However, a significant number of patients are undiagnosed or untreated. Given the complexities of detecting cognitive impairment and the early signs of AD, this review discusses how advances in brain imaging can help assist in improving overall management. Imaging techniques and surrogate markers may provide unique opportunities to diagnose accurately AD in presymptomatic stages with practical consequences for patients, caregivers, and physicians. The possible outcomes for using imaging and surrogate markers as adjuncts to clinical examination and as screening tools for AD, as well as tangible and intangible advantages to early diagnosis and treatment, will be discussed. The specific value of using advanced serial imaging in patients with a genetic disposition to AD will be evaluated. If neurons can be protected from neurodegenerative damage in early stages, this may preserve patient cognition, function, and quality of life, and may confer considerable societal healthcare benefits.

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Pengaruh pelatihan kader yandu lansia dalam menciptakan desa ramah dan sehat lansia di Desa Purwobinangun, Sleman

Journal of Community Empowerment for Health ◽

10.22146/jcoemph.41273 ◽

2019 ◽

Vol 2 (2) ◽

Author(s):

Sumarni Sumarni ◽

Adi Heru Sutomo ◽

Cempaka Tursina ◽

Purwanta Purwanta ◽

Ade Indah Wahdini ◽

...

Keyword(s):

Quality Of Life ◽

Social Support ◽

Cognitive Impairment ◽

Old Age ◽

Health Problem ◽

Elderly Care ◽

Depression Scale ◽

Secondary Data ◽

Community Research

Merapi eruption can cause a psychological traumatic for elderly such as depression, increase disability, and decrease quality of life. We need to train the cadres to make an elderly care village. The study aim is to know the influence of cadre training on knowledge and skill for elderly healthiness. This study uses secondary data from community research on May until September 2018 in Desa Purwobinangun, Sleman. The target is cadres and 80 elderlies in Desa Purwobinangun, Sleman. The tools in this study such as Module Ramah dan Sehat Lansia, Geriatric Depression Scale (GDS), Mini-Mental State Examination (MMSE), questionnaire about knowledge and skills of traditional games, and questionnaire about early detection and treatment in old age health. The data will be shown in quantitative data. After trained, the result was showed: 1) average points of knowledge about health problem in old age especially in social support increased 50%; traditional game increased 30%; old friendly increased 45%; and brain games increased 40%. 2) average points of skills to treat elderly health problem especially in social support elevated 19,81%; traditional games rose 17,02%; elderly care increased 27,58%; and brain games increased 28,68%. 3) tendency to get health problem in elderly: hypertension decreased 8,75%, diabetes mellitus stayed at 37 subjects; depression decreased 22,5%; good cognitive increased 16,25%; moderate cognitive impairment decreased 16,28%; and severe cognitive impairment stayed at 9 subjects; and low quality of life was decreased 27,5%). Cadres empowerment can increase knowledge and skill of cadre to treat health problems in elderly.

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