Unusual complications following left ventricular assisted device implantation: case series

Abstract Background While left ventricular assisted devices (LVAD) have revolutionized the treatment of advanced heart failure, they are associated with a wide range of complications, including bleeding and infection which are the most common complications reported in the literature. Our case series report four unusual complications not related to gastrointestinal bleeding and infections and their management. Case presentation A 61 year old female after LVAD implantation with late onset of severe symptomatic aortic regurgitation treated by transfemoral transcatheter valve implantation (TAVI) with good long term results. A 75 year old male patient with acute pump failure secondary to cable damage, who underwent urgent pump replacement. A 49 year old female patient with a history of myoma who developed massive uterine bleeding which was treated with emergent open hysterectomy after failed gonadotropin-releasing hormone therapy replacement. A 57 year old male patient with device display failure 1 month after LVAD implantation without the ability to monitor speed, power consumption and blood flow. Conclusions LVAD patients can be presented with a great variety of complications. Physicians should be aware of their manifestations and the management options.

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Unusual Complications Following Left Ventricular Assisted Device Implantation: Case Series

10.21203/rs.3.rs-38988/v1 ◽

2020 ◽

Author(s):

Amjad Shalabi ◽

Erez Kachel ◽

Yigal Kassif ◽

Muin Faqeeh ◽

Sergey Preisman ◽

...

Keyword(s):

Gastrointestinal Bleeding ◽

Male Patient ◽

Late Onset ◽

Case Series ◽

Left Ventricular ◽

Long Term Results ◽

Pump Failure ◽

Wide Range ◽

Case Series Report ◽

Transcatheter Valve

Abstract Background:While left ventricular assisted devices (LVAD) have revolutionized the treatment of advanced heart failure, they are associated with a wide range of complications, including bleeding and infection which are the most common complications reported in the literature. Our case series report four unusual complications not related to gastrointestinal bleeding and infections and their management.Case presentation: A sixty one year old female after LVAD implantation with late onset of severe symptomatic aortic regurgitation treated by transfemoral transcatheter valve implantation (TAVI) with good long term results. A Seventy-five year old male patient with acute pump failure secondary to cable damage, who underwent urgent pump replacement. A forty-nine year old female patient with a history of myoma who developed massive uterine bleeding which was treated with emergent open hysterectomy after failed gonadotropin-releasing hormone therapy replacement. A fifty-seven year old male patient with device display failure one month after LVAD implantation without the ability to monitor speed, power consumption and blood flow.Conclusions:The incidence of LVAD complications not related to gastrointestinal bleeding and infections is variable and generally unexpected. It is important to know these complications and their management.

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Safety and efficacy of posterior iris claw intraocular lens fixation in aphakic patients

Asian Journal of Ophthalmology ◽

10.35119/asjoo.v16i2.368 ◽

2018 ◽

Vol 16 (2) ◽

pp. 124-133

Author(s):

Rosemary Tomy ◽

Rajkumar Maheshwari ◽

Ansa Parveen Kunhu Muhammed ◽

Venkataramana Kalikivayi ◽

Sajeev Cherian Jacob

Keyword(s):

Intraocular Lens ◽

Anterior Segment ◽

Case Series ◽

Visual Outcome ◽

Applanation Tonometry ◽

Long Term Results ◽

Retrospective Case ◽

Case Series Study ◽

Wide Range

Purpose: To assess the indications and visual outcome of eyes undergoing posterior iris fixated intraocular lens (IFIOL) implantation for aphakia, to identify reasons for poor visual outcome, and report occurrence of complications. Methods: In this retrospective case series study, all cases of posterior IFIOL fixation performed over a 30-month period were identified retrospectively. Preoperative and postoperative evaluations comprised objective and subjective refraction, best corrected visual acuity (BCVA), slit lamp biomicroscopy, applanation tonometry, and dilated fundus examination. Results: Fifty-six eyes of 56 patients were analyzed. Mean age was 60.55 ± 17.2 years. The most common indication for IFIOL implantation was surgical aphakia following complicated cataract surgery (n = 33; 58.9%) followed by trauma (n = 10; 17.9%), dropped nucleus/IOL during primary surgery (n = 6; 10.7%), and subluxated/dislocated lens-induced glaucomas (n = 5; 8.9%). BCVA better than or equal to their preoperative BCVA was achieved in 96.43% patients. The surgical aphakia and paediatric/adolescent groups had the best visual results while the dropped nucleus/IOL group and subluxated lens-induced glaucoma groups fared poorly. On the long-term follow-up visit, the most common complication noted was pigment dusting on the corneal endothelium (65.7%). Conclusion: The long-term results suggest that posterior IFIOL implantation is a safe and effective method for correction of aphakia and can be used for a wide range of indications in eyes without adequate capsule support. It may be considered an easier and faster alternative with minimal manipulation to anterior segment structures in paediatric and post-traumatic aphakic eyes.

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Neurologic Features Associated With SARS-CoV-2 Infection in Children: A Case Series Report

Journal of Child Neurology ◽

10.1177/0883073821989164 ◽

2021 ◽

pp. 088307382198916

Author(s):

Francisca Sandoval ◽

Katherine Julio ◽

Gastón Méndez ◽

Carolina Valderas ◽

Alejandra C. Echeverría ◽

...

Keyword(s):

Pediatric Population ◽

Case Series ◽

Neurologic Manifestations ◽

Retrospective Case ◽

Neurologic Symptoms ◽

Clinical Presentations ◽

Wide Range ◽

Neurophysiological Studies ◽

Case Series Report ◽

Series Report

Introduction: Although multiple neurologic manifestations associated with SARS-CoV-2 infection have been described in adults, there is little information about those presented in children. Here, we described neurologic manifestations associated with COVID-19 in the pediatric population. Methods: Retrospective case series report. We included patients younger than 18 years, admitted with confirmed SARS-CoV-2 infection and neurologic manifestations at our hospital in Santiago, Chile. Demographics, clinical presentations, laboratory results, radiologic and neurophysiological studies, treatment, and outcome features were described. Cases were described based on whether they presented with predominantly central or peripheral neurologic involvement. Results: Thirteen of 90 (14.4%) patients admitted with confirmed infection presented with new-onset neurologic symptoms and 4 patients showed epilepsy exacerbation. Neurologic manifestations ranged from mild (headache, muscle weakness, anosmia, ageusia), to severe (status epilepticus, Guillain-Barré syndrome, encephalopathy, demyelinating events). Conclusions: We found a wide range of neurologic manifestations in children with confirmed SARS-CoV-2 infection. In general, neurologic symptoms were resolved as the systemic presentation subsided. It is essential to recognize and report the main neurologic manifestations related to this new infectious disease in the pediatric population. More evidence is needed to establish the specific causality of nervous system involvement.

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Intramyocardial dissecting haematoma mimicking left ventricular clot, a rare complication of myocardial infarction: a case report

European Heart Journal - Case Reports ◽

10.1093/ehjcr/ytz056 ◽

2019 ◽

Vol 3 (2) ◽

Author(s):

Tjen Jhung Lee ◽

Aslannif Roslan ◽

Khai Chih Teh ◽

Azmee Ghazi

Keyword(s):

Myocardial Infarction ◽

Case Reports ◽

Rare Complication ◽

Case Series ◽

Left Ventricular ◽

Pump Failure ◽

Case Summary ◽

Risk Of Mortality ◽

Endocardial Layer ◽

Supportive Management

Abstract Background Intramyocardial dissecting haematoma is a rare complication of myocardial infarction (MI) associated with high mortality rates. Studies and research of this occurrence are limited largely to isolated case reports or case series. Case summary We report a case of late presenting MI, where on initial echocardiogram had what was thought to be an intraventricular clot. However, upon further evaluation, the patient actually had an intramyocardial haematoma, with the supporting echocardiographic features to distinguish it from typical left ventricular (LV) clot. While this prevented the patient from receiving otherwise unnecessary anticoagulation, this diagnosis also put him at a much higher risk of mortality. Despite exhaustive medical and supportive management, death as consequence of pump failure occurred after 2 weeks. Discussion This report highlights the features seen on echocardiography which support the diagnosis of an intramyocardial haematoma rather than an LV clot, notably the various acoustic densities, a well visualized myocardial dissecting tear leading into a neocavity filled with blood, and an independent endocardial layer seen above the haematoma. Based on this report, we wish to highlight the importance of differentiating intramyocardial haematomas from intraventricular clots in patients with recent MI.

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Treatment Modalities for Multiple Gingival Recession– A New Prospects

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i631190 ◽

2021 ◽

pp. 65-83

Author(s):

Ena Sharma ◽

Amit Lakhani ◽

Rasveen Kaur ◽

Ravneet Kaur

Keyword(s):

Soft Tissues ◽

Surgical Techniques ◽

Case Series ◽

Multiple Root ◽

Gingival Recession ◽

Long Term Results ◽

Treatment Modalities ◽

Platelet Rich Fibrin ◽

Advantages And Disadvantages ◽

Wide Range

This case series reports the various treatment modalities to treat the multiple recessions. Gingival recession is a widespread clinical manifestation affecting single or multiple root surfaces at all teeth types. Periodontal reconstructive surgery consists of various mucogingival procedures. The primary goal of these procedures is to benefit periodontal health through the reconstruction of lost hard and soft tissues, or by preventing its additional loss, and also enhancing the esthetic appearance. Platelet-rich fibrin is a second generation platelet concentrate and is defined as an autologous leukocyte and platelet-rich fibrin biomaterial. Care was taken not to extend the incisions till the tip of the interdental papilla. A full thickness mucoperiosteal flap was reflected, extending beyond the mucogingival junction. A wide range of surgical techniques has been proposed for the treatment of the gingival recessions, each with its advantages and disadvantages. To provide predictable and long-term results, it is of paramount importance that the surgical technique is individually selected, taking into account several crucial factors such as the size of the defect, the width of the keratinised gingiva apical to the defect and the thickness of the flap.

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https://researchopenworld.com/dont-break-my-heart-a-case-series-report-of-acute-traumatic-injury-in-left-ventricular-assist-device-lvad-patients/#

10.31038/srr.2018112 ◽

2018 ◽

Vol 1 (1) ◽

Keyword(s):

Left Ventricular Assist Device ◽

Ventricular Assist Device ◽

Traumatic Injury ◽

Case Series ◽

Left Ventricular ◽

Assist Device ◽

Ventricular Assist ◽

Left Ventricular Assist ◽

Case Series Report ◽

Series Report

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Virtual Eye Simulation: An Aid in Evaluation of Capsular Block Syndrome

The Open Ophthalmology Journal ◽

10.2174/1874364101913010051 ◽

2019 ◽

Vol 13 (1) ◽

pp. 51-56

Author(s):

Joseph L. Hu ◽

Chao-Chien Hu

Keyword(s):

Intraocular Lens ◽

Yttrium Aluminum Garnet ◽

Late Onset ◽

Case Series ◽

Posterior Chamber ◽

Nd:Yag Laser Capsulotomy ◽

Case Series Report ◽

Blurry Vision ◽

The One ◽

Capsular Block Syndrome

Objective: To demonstrate the findings of three consecutive cases of postoperative Capsular Block Syndrome (CBS) diagnosed with the aid of Pentacam virtual eye simulation images. Methods: Observational case series report. Three patients underwent uneventful cataract removal and presented with blurry vision ranging from 4 days to 5 years after the surgeries were performed. Results: In a case of early-onset postoperative CBS, virtual eye simulation images clearly revealed a reduced posterior chamber depth caused by the accumulation of transparent fluid in the area between the intraocular lens and the posterior capsule. In two cases of late-onset postoperative CBS, virtual eye simulation images better visualized the alignment between intraocular lens (IOL) and iris than slit lamp examination and Schiemflug images. All three of the cases underwent neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy, and their capsular bag distensions were resolved immediately. The patients with misalignments between IOL and iris experienced more improvement in best-corrected visual acuity as opposed to the one who did not. Conclusion: Virtual eye simulation is found to be a useful way in visualizing misalignment between IOL and iris and assisting diagnoses of both early- and late-onset postoperative capsular block syndrome.

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Management of inappropriate sexual behaviors in dementia: a literature review

International Psychogeriatrics ◽

10.1017/s1041610210000189 ◽

2010 ◽

Vol 22 (5) ◽

pp. 683-692 ◽

Cited By ~ 53

Author(s):

Inese Tucker

Keyword(s):

Sexual Behavior ◽

Sexual Behaviors ◽

Case Reports ◽

Case Series ◽

Pharmacological Agents ◽

Inappropriate Sexual Behavior ◽

Wide Range ◽

Case Series Report ◽

Sexual Disinhibition ◽

Psychoactive Medications

ABSTRACTBackground: This paper reviews published literature on the pharmacological and non-pharmacological treatment of inappropriate sexual behavior in dementia.Methods: A literature search of Psychinfo and Cochrane databases was performed and data from case reports and case series were analyzed.Results: No randomized controlled trials exist for any treatment of sexual disinhibition in dementia and there are no trials comparing different pharmacological agents. Case reports and case series report a wide range of pharmacotherapies as efficacious in the treatment of inappropriate sexual behaviors in dementia. There is only one case report of non-pharmacological strategies to manage inappropriate sexual behavior.Conclusions: Inappropriate sexual behaviors in dementia can be difficult to treat. Frequently, multiple psychoactive medications are used and many pharmacotherapies are trialed prior to finding an effective agent. More research is needed to clarify the usefulness of these medications and to identify non-pharmacological strategies to prevent unnecessary use of medications.

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Restoration Of Left Ventricular Function Following LVAD Implantation – Remission Or Recovery? A Case series

The VAD Journal ◽

10.14434/vad.v4i0.28050 ◽

2018 ◽

Author(s):

Shiksha Joshi ◽

Mariah Barlow ◽

Maya Guglin

Keyword(s):

Mechanical Circulatory Support ◽

Case Series ◽

Left Ventricular ◽

Circulatory Support ◽

Lv Function ◽

Ventricular Assist ◽

Wide Range ◽

Left Ventricular Assist ◽

The Status ◽

Lvad Support

Background A wide range of left ventricular (LV) recovery rates on left ventricular assist device (LVAD) support have been reported. In this case series, we summarize our experience with LVAD explantation for presumed LV recovery. Case series Out of 240 patients who received an LVAD implant in our program since its inception, we explanted/inactivated the pump for presumed LV recovery in only three patients. All three of these patients had relapse of cardiomyopathy within 6 months of explantation. Conclusion Our experience does not support the existence of LV recovery following LVAD implantation as a common phenomenon. Improvement in LV function on LVAD is sustainable only with mechanical circulatory support and once the offloading support provided by the device is removed recurrent failure quickly ensue. Likely the term “remission” reflects the status more accurately than the term “recovery”.

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