Sleep disturbance, psychiatric issues, and employment status of Iranian people living with HIV

Abstract Objectives There are limited studies on the psychological issues and sleep problems among the Iranian people living with HIV (HIV). In this study, we aimed to assess sleep disorders, psychiatric characteristics, and employment status among Iranian PLWH. Results In total, 304 PLWH with a mean age of 40.01 (SD = 9.60) years participated in the study. About 72% of the participants had a global PSQI score of more than 5, with a mean score of 7.71 (SD = 3.31). About 55.6%, 50%, and 67.4% of subjects had abnormal scores for depression, anxiety, and stress. Unemployed participants had 2.13 times more chance (95% CI 1.01–4.53) of having poor sleep quality compared to employed patients, and stress increased its likelihood by 3.18 times (95% CI 1.47–5.88).

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Quality of sleep and associated factors among people living with HIV/AIDS on follow up at Ethiopian Zewditu Memorial Hospital,2018

10.21203/rs.3.rs-26745/v3 ◽

2020 ◽

Author(s):

Nebiyu Mengistu ◽

Telake Azale ◽

Solomon Yimer ◽

Mahilet Fikreyesus ◽

Elsa Melaku ◽

...

Keyword(s):

Sleep Quality ◽

Sleep Disturbance ◽

Associated Factors ◽

Poor Sleep ◽

People Living With Hiv ◽

Quality Of Sleep ◽

Poor Sleep Quality ◽

Living With Hiv ◽

Hiv Aids

Abstract Background: Sleep disturbance is a common complaint in people living with HIV/AIDS. Despite the influence of sleep disturbance on treatment adherence, quality of life, work productivity, risk of chronic illness, it remains under-recognized and under-studied in Ethiopia. Therefore it is necessary to produce scientific evidence to fill the knowledge gap and areas of management. The current study aimed to assess sleep quality and its associated factors among people living with HIV/AIDS. Methods: An institution-based cross-sectional study was utilized among 408 participants who were selected by a systematic random sampling technique at Zewditu memorial hospital from April to May 2018. The Pittsburgh Sleep Quality Index questionnaire was used to measure sleep quality. Ethical clearance was obtained from the joint ethics committee of the University of Gondar and Amanuel Mental Specialized Hospital. Oral informed consent was obtained from each participant. Binary and multivariable logistic regression models were fitted. Odds ratios (OR) with the corresponding 95% confidence interval (95%CI) was computed. Results: The magnitude of poor sleep quality was 55.6%. Being female [AOR=3.40, 95% CI: (1.80, 6.41)], depression [AOR =3.52, 95% CI: (1.95, 6.32)], CD4count ≤ 200 cells/mm3 [AOR=3.18,95%CI: (1.65,6.13)], duration of HIV/AIDS diagnosis [AOR=3.43,95% CI: (1.61,7.29)], current use of tobacco [AOR=5.69, 95% CI: (2.04,15.9)] and chat or caffeinated drinks [AOR=2.65, 95% CI: (1.06,6.64)] and poor sleep hygiene [AOR=3.55, 95% CI: (1.85, 6.78)] were significantly associated with poor sleep quality.Conclusions: More than half of the study participants were found to have poor sleep quality. A range factors influence quality of sleep of people with HIV/AIDS. Routine screening of sleep condition among people living with HIV/AIDS and early intervention based on the findings is suggested.

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Quality of sleep and associated factors among people living with HIV/AIDS on follow up at Ethiopian Zewditu memorial hospital, 2018

Sleep Science and Practice ◽

10.1186/s41606-020-00056-w ◽

2021 ◽

Vol 5 (1) ◽

Author(s):

Nebiyu Mengistu ◽

Telake Azale ◽

Solomon Yimer ◽

Mahlet Fikreyesus ◽

Elsa Melaku ◽

...

Keyword(s):

Sleep Quality ◽

Sleep Disturbance ◽

Associated Factors ◽

Poor Sleep ◽

People Living With Hiv ◽

Quality Of Sleep ◽

Poor Sleep Quality ◽

Living With Hiv ◽

Hiv Aids

Abstract Background Sleep disturbance is a common complaint in people living with HIV/AIDS. Despite the influence of sleep disturbance on treatment adherence, quality of life, work productivity, risk of chronic illness, it remains under-recognized and under-studied in Ethiopia. Therefore it is necessary to produce scientific evidence to fill the knowledge gap and areas of management. The current study aimed to assess sleep quality and its associated factors among people living with HIV/AIDS. Methods An institution-based cross-sectional study was utilized among 408 participants who were selected by a systematic random sampling technique at Zewditu memorial hospital from April to May 2018. The Pittsburgh Sleep Quality Index questionnaire was used to measure sleep quality. Ethical clearance was obtained from the joint ethics committee of the University of Gondar and Amanuel Mental Specialized Hospital. Oral informed consent was obtained from each participant. Binary and multivariable logistic regression models were fitted. Odds ratios (OR) with the corresponding 95% confidence interval (95%CI) was computed. Results The magnitude of poor sleep quality was 55.6%. Being female [AOR = 3.40, 95% CI: (1.80, 6.41)], depression [AOR =3.52, 95% CI: (1.95, 6.32)], CD4count ≤ 200 cells/mm3 [AOR = 3.18,95%CI: (1.65,6.13)], duration of HIV/AIDS diagnosis [AOR = 3.43,95% CI: (1.61,7.29)], current use of tobacco [AOR = 5.69, 95% CI: (2.04,15.9)] and chat or caffeinated drinks [AOR = 2.65, 95% CI: (1.06,6.64)] and poor sleep hygiene [AOR = 3.55, 95% CI: (1.85, 6.78)] were significantly associated with poor sleep quality. Conclusions More than half of the study participants were found to have poor sleep quality. A range factors influence quality of sleep of people with HIV/AIDS. Routine screening of sleep condition among people living with HIV/AIDS and early intervention based on the findings is suggested.

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Sleep Disturbance, Psychiatric Issues, and Employment Status of Iranian People Living with HIV

10.21203/rs.3.rs-645998/v1 ◽

2021 ◽

Author(s):

Arezu Najafi ◽

Marzieh Mahboobi ◽

Saber Soltani ◽

Ali Jafarpour ◽

Khosro Sadeghniiat Haghighi ◽

...

Keyword(s):

Sleep Disturbance ◽

Employment Status ◽

Response To Treatment ◽

Poor Sleep ◽

People Living With Hiv ◽

High Risk Behaviors ◽

Living With Hiv ◽

Treatment Prognosis ◽

Psychiatric Problems ◽

Psychiatric Issues

Abstract Objectives. Psychiatric problems and sleep disturbance among people living with HIV (PLWH) are associated with response to treatment, prognosis, and high-risk behaviors. We aimed to assess sleep disorders, psychiatric characteristics, and employment status among Iranian PLWH. Results. In total, 304 patients with a mean age of 40.01 (SD=9.60) years participated in the study. About 72% of the participants had a global PSQI score of more than 5, with a mean of 7.71 (SD=3.31). About 55.6%, 50%, and 67.4% of patients had abnormal scores for depression, anxiety, and stress. Unemployed patients had 2.13 times more chance (95% CI: 1.01-4.53) of having poor sleep quality compared to employed patients, and stress increased its likelihood by 3.18 times (95% C: 1.47-5.88).

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Multimodality assessment of sleep outcomes in people living with HIV performed using validated sleep questionnaires

International Journal of STD & AIDS ◽

10.1177/0956462420941693 ◽

2020 ◽

Vol 31 (10) ◽

pp. 996-1003 ◽

Cited By ~ 1

Author(s):

Ana Milinkovic ◽

Suveer Singh ◽

Bryony Simmons ◽

Anton Pozniak ◽

Marta Boffito ◽

...

Keyword(s):

Drug Use ◽

Sleep Quality ◽

Sleep Disturbance ◽

Comprehensive Evaluation ◽

Poor Sleep ◽

People Living With Hiv ◽

Recreational Drug ◽

Cd4 Cell Count ◽

Recreational Drug Use ◽

Living With Hiv

Studies conducted in people living with HIV (PLHIV) report high rates of sleep disturbance, without a clear explanation as to cause or effect. Therefore, we proposed use of multiple validated questionnaires that would allow a more comprehensive evaluation of sleep quality in PLHIV. We administered eight validated sleep and wellbeing questionnaires, recording different aspects of sleep in order to provide a comprehensive description of sleep quality, quantity, daytime functioning, wakefulness, and general wellbeing. Associations with demographics and clinical data were analyzed by univariable/multivariable analyses. Of 254 subjects 99% were male (98% men who have sex with men), 88% white, mean age 41 (SD ± 9.9) years, HIV duration eight years (SD ± 6.3), 94% were on antiretroviral therapy, mean CD4 cell count was 724 cells/mm3, 81% had HIV RNA<40 copies/ml, 72% were university educated, and 60% used ‘chemsex’ drugs. Almost half (45%) reported poor sleep quality, 22% insomnia, 21% daytime sleepiness, and 33% fatigue. As individual factors, HIV duration ≥10 years, anxiety, depression, and recreational drug use were associated with poor quality sleep, fatigue, and poorer functional outcomes (p ≤ 0.05). The prevalence of sleep disturbance was high in our cohort of PLHIV. Sleep disturbance was associated with longer duration of HIV infection, depression, anxiety, and recreational drug use.

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Quality of sleep and associated factors among people living with HIV/AIDS on follow up at Ethiopian Zewditu Memorial Hospital,2018

10.21203/rs.3.rs-26745/v2 ◽

2020 ◽

Author(s):

Nebiyu Mengistu ◽

Telake Azale ◽

Solomon Yimer ◽

Mahilet Fikreyesus ◽

Elsa Melaku ◽

...

Keyword(s):

Sleep Quality ◽

Associated Factors ◽

Poor Sleep ◽

People Living With Hiv ◽

Quality Of Sleep ◽

Poor Sleep Quality ◽

Sleep Condition ◽

Living With Hiv ◽

Hiv Aids

Abstract Background: Sleep disturbance is a common complaint in people living with HIV/AIDS. Individuals with it are less likely to adhere to their treatment, have decreased quality of life, have decreased work productivity, and have increased risk of psychiatric disorders, cardiovascular morbidity, and disease progression. However, sleep condition remains under-recognized by clinicians and is not well studied in Ethiopia. Therefore it is necessary to produce scientific evidence to fill the clinical knowledge gap and recommend the focus area of management. The aim of the study was to assess sleep quality and its associated factors among people living with HIV/AIDS. Methods: An institution-based cross-sectional study was utilized among 408 participants who were selected by a systematic random sampling technique at Zewditu memorial hospital from April to May 2018. The Pittsburgh Sleep Quality Index questionnaire was used to measure sleep quality. Ethical clearance was obtained from the joint ethics committee of the University of Gondar and Amanuel Mental Specialized Hospital. Oral informed consent was obtained from each participant. Binary and multivariable logistic regression models were fitted. Odds ratios (OR) with the corresponding 95% confidence interval (95%CI) was computed to assess the strength of the association. Results: The magnitude of poor sleep quality was 55.6%. Being female [AOR=3.40, 95% CI: (1.80, 6.41)], depression [AOR =3.52, 95% CI: (1.95, 6.32)], CD4count ≤ 200 cells/mm3 [AOR=3.18,95%CI: (1.65,6.13)], duration of HIV/AIDS diagnosis [AOR=3.43,95% CI: (1.61,7.29)], current use of tobacco [AOR=5.69, 95% CI: (2.04,15.9)] and chat or caffeinated drinks [AOR=2.65, 95% CI: (1.06,6.64)] and poor sleep hygiene [AOR=3.55, 95% CI: (1.85, 6.78)] were significantly associated with poor sleep quality. Conclusions: More than half of the study participants were found to have poor sleep quality. A range factors influence quality of sleep of people with HIV/AIDS. Routine screening of sleep condition among people living with HIV/AIDS and early intervention based on the findings is suggested.

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Prevalence of Sleep Disturbance and Potential Associated Factors among Medical Students from Mashhad, Iran

Sleep Disorders ◽

10.1155/2020/4603830 ◽

2020 ◽

Vol 2020 ◽

pp. 1-4

Author(s):

Ahmad Janatmakan Amiri ◽

Negar Morovatdar ◽

Atefeh Soltanifar ◽

Ramin Rezaee

Keyword(s):

Medical Students ◽

Sleep Quality ◽

Sleep Disturbance ◽

Sleep Disorders ◽

Associated Factors ◽

Sleep Problems ◽

Poor Sleep ◽

Poor Sleep Quality ◽

Related Factors ◽

Cross Sectional

Study Objectives. A very limited number of studies have evaluated the prevalence of sleep problems, and related factors, in Iranian medical students. The aim of this study was to determine the prevalence of sleep disturbance and potential associated factors among medical students of Mashhad University of Medical Sciences, Mashhad, Iran. Methods. In this cross-sectional study, 315 medical students chosen by stratified random sampling participated in the academic year 2018-2019. The Pittsburgh Instrument and DASS-21 questionnaire were used to evaluate sleep quality and anxiety, depression, and stress, respectively. Also, demographic, educational, and socioeconomic information was collected. SPSS 16 software was used for data analysis. Results. Out of 300 students who completed the questionnaires, 165 (55%) were male, with a mean age of 21.94±2.28 years old. The prevalence of poor sleep quality was 51.3%. We did not find significant associations among age, sex, and poor sleep quality. Concurrent psychological symptoms such as stress, depression, and anxiety were significantly associated with sleep disorders. After adjusting variables in the multivariable regression model, depression (OR=2.81, 95% CI: 1.35-5.87; p=0.006) and the number of hours spent on using smartphones in 24 hours (OR=1.13, 95% CI: 1.02-1.25; p=0.01) were significantly associated with poor sleep quality among medical students. Conclusion. The prevalence of poor sleep quality among medical students was high, and we found that increased use of smartphones during the day and depression were associated with sleep disorders.

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Association between sleep quality and central obesity among southern Chinese reproductive-aged women

10.21203/rs.3.rs-15728/v1 ◽

2020 ◽

Author(s):

Bingbing Li ◽

Nan Liu ◽

Donghui Guo ◽

Bo Li ◽

Yan Liang ◽

...

Keyword(s):

Sleep Quality ◽

Sleep Disturbance ◽

Central Obesity ◽

Sleep Problems ◽

Poor Sleep ◽

Poor Sleep Quality ◽

Independent Contribution ◽

Southern Chinese ◽

Health Related ◽

Reproductive Aged Women

Abstract Background Females are more prone to complain about sleep problems. Poor sleep quality in this group may make them more vulnerable to suffering obesity and other diseases, which can seriously affect their fitness and quality of life. Nevertheless, the connections between sleep quality and central obesity among reproductive-aged women are not clear. The aims of this study were to explore the association between sleep quality as measured by the Pittsburgh Sleep Quality Index (PSQI) and central obesity among Chinese reproductive-aged women and to identify the independent contributions of sociodemographic characteristics, health-related factors, and sleep quality to central obesity. Methods In this cross-sectional survey, 2449 Chinese reproductive-aged women aged 18-49 years were studied. Sleep quality was assessed using the Chinese version of the PSQI. Central obesity as the outcome of interest was a binary variable; women were categorized as with versus without central obesity. Clustered logistic regression was used to analyze the independent contribution of sleep quality to central obesity. Results The risk of central obesity increased significantly with poor sleep quality (assessed by global PSQI score) (adjusted OR(Odds Ratio)=2.20 per SD increase; P=0.004), increased sleep disturbance score (adjusted OR=1.11 per SD increase; P=0.042) and decreased subjective sleep quality score (adjusted OR=0.81 per SD increase; P<0.001). The independent contribution of sleep quality was 9.9%, less than those of sociodemographic (73.3%) and health-related (16.8%) variables. Among complaints related to sleep disturbance, the inability to breathe comfortably and having bad dreams showed significant associations with central obesity. Conclusions There exists some degree of correlation between sleep quality and central obesity among Chinese reproductive-aged women. Understanding this link has public health relevance because of the important role sleep plays in health. It also has some implications for the discovery of novel strategies to prevent central obesity and the implementation of weight maintenance programs in this population group.

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Quality of sleep and associated factors among people living with HIV/AIDS on follow up at Ethiopian Zewditu Memorial Hospital,2018

10.21203/rs.3.rs-26745/v1 ◽

2020 ◽

Author(s):

Nebiyu Mengistu ◽

Telake Azale ◽

Solomon Yimer ◽

Mahilet Fikreyesus ◽

Elsa Melaku ◽

...

Keyword(s):

Sleep Quality ◽

Systematic Sampling ◽

P Value ◽

Poor Sleep ◽

People Living With Hiv ◽

Poor Sleep Quality ◽

Cross Sectional ◽

Living With Hiv ◽

Hiv Aids

Abstract Background Sleep disturbance is a common complaint in people living with HIV/AIDS. Those individuals with it are less likely to adhere to their antiretroviral therapy regimens, have decreased quality of life, have decreased work productivity as well as it may increase the risk for psychiatric disorders, cardiovascular morbidity and disease progression. However, it is not well studied in Ethiopia. Methods An institution based cross-sectional study was utilized among 408 participants selected by systematic sampling technique. The Pittsburgh Sleep Quality Index questionnaire was used to measure sleep quality. Binary and multivariable logistic regression models were fitted. Odds ratios (OR) with the corresponding 95% confidence interval (95%CI)) was computed to assess the strength of association. P-value < 0.05 was considered as statistically significant. Results The magnitude of poor sleep quality was 55.6%. Being female [AOR = 3.40, 95% CI: (1.80, 6.41)], depression [AOR = 3.52, 95% CI: (1.95, 6.32)], CD4count ≤ 200 cells/mm3 [AOR = 3.18,95%CI: (1.65,6.13)], duration of HIV/AIDS diagnosis [AOR = 3.43,95% CI: (1.61,7.29)], current use of tobacco [AOR = 5.69, 95% CI: (2.04,15.9)] and chat or caffeinated drinks [AOR = 2.65, 95% CI: (1.06,6.64)] and poor sleep hygiene [AOR = 3.55, 95% CI: (1.85, 6.78)] were significantly associated with poor sleep quality. Conclusions More than half of the study participants were found to have poor sleep quality. Routine screening of sleep condition among people living with HIV/AIDS and early intervention based on the findings is suggested.

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Gambling Problems Are Associated with Alcohol Misuse and Insomnia: Results from a Representative National Telephone Survey

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18136683 ◽

2021 ◽

Vol 18 (13) ◽

pp. 6683

Author(s):

Hannah Briony Thorne ◽

Matthew Justus Rockloff ◽

Sally Anne Ferguson ◽

Grace Elizabeth Vincent ◽

Matthew Browne

Keyword(s):

At Risk ◽

Alcohol Consumption ◽

Sleep Quality ◽

Problem Gambling ◽

Alcohol Misuse ◽

Sleep Problems ◽

Online Gambling ◽

Poor Sleep ◽

Gambling Problems ◽

Poor Sleep Quality

Gambling has significant costs to the community, with a health burden similar in scale to major depression. To reduce its impact, it is necessary to understand factors that may exacerbate harm from gambling. The gambling environment of late-night licensed venues and 24/7 online gambling has the potential to negatively impact sleep and increase alcohol consumption. This study explored gambling, alcohol, and sleep problems to understand whether there is a relationship between these three factors. Telephone interviews were conducted with a representative sample of Australian adults (n = 3760) combined across three waves of the National Social Survey. Participants completed screening measures for at-risk gambling, at-risk alcohol consumption, insomnia (2015 wave only), and sleep quality. There were small but significant positive correlations between problem gambling and alcohol misuse, problem gambling and insomnia, and problem gambling and poor sleep quality. A regression model showed that gambling problems and alcohol misuse were significant independent predictors of insomnia. A separate regression showed gambling problems (and not alcohol misuse) were a significant predictor of poor sleep quality, but only in one survey wave. Findings suggest that gambling, alcohol, and sleep problems are related within persons. Further research should examine the mechanisms through which this relationship exists.

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Left superior temporal sulcus morphometry mediates the impact of anxiety and depressive symptoms on sleep quality in healthy adults

Social Cognitive and Affective Neuroscience ◽

10.1093/scan/nsab012 ◽

2021 ◽

Author(s):

Yanlin Wang ◽

Ping Jiang ◽

Shi Tang ◽

Lu Lu ◽

Xuan Bu ◽

...

Keyword(s):

Depressive Symptoms ◽

Sleep Quality ◽

Sleep Problems ◽

Superior Temporal Sulcus ◽

Healthy Adults ◽

Poor Sleep ◽

Emotional Symptoms ◽

Neural Basis ◽

Poor Sleep Quality ◽

The Impact

Abstract Anxiety and depressive symptoms may predispose individuals to sleep disturbance. Understanding how these emotional symptoms affect sleep quality, especially the underlying neural basis, could support the development of effective treatment. The aims of the present study were therefore to investigate potential changes in brain morphometry associated with poor sleep quality and whether this structure played a mediating role between the emotional symptoms and sleep quality. One hundred and forty-one healthy adults (69 women, mean age = 26.06 years, SD = 6.36 years) were recruited. A structural magnetic resonance imaging investigation was performed, and self-reported measures of anxiety, depressive symptoms and sleep quality were obtained for each participant. Whole-brain regression analysis revealed that worse sleep quality was associated with thinner cortex in left superior temporal sulcus (STS). Furthermore, the thickness of left STS mediated the association between the emotional symptoms and sleep quality. A subsequent commonality analysis showed that physiological component of the depressive symptoms had the greatest influence on sleep quality. In conclusion, thinner cortex in left STS may represent a neural substrate for the association between anxiety and depressive symptoms and poor sleep quality and may thus serve as a potential target for neuromodulatory treatment of sleep problems.

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