scholarly journals Using tocolysis in pregnant women with symptomatic placenta praevia does not significantly improve prenatal, perinatal, neonatal and maternal outcomes: a systematic review and meta-analysis

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Frederick Morfaw ◽  
Mercy Fundoh ◽  
Jessica Bartoszko ◽  
Lawrence Mbuagbaw ◽  
Lehana Thabane
2021 ◽  
Vol 10 (4) ◽  
pp. 666
Author(s):  
Fahimeh Ramezani Tehrani ◽  
Marzieh Saei Ghare Naz ◽  
Razieh Bidhendi Yarandi ◽  
Samira Behboudi-Gandevani

This systematic review and meta-analysis aimed to examine the impact of different gestational-diabetes (GDM) diagnostic-criteria on the risk of adverse-maternal-outcomes. The search process encompassed PubMed (Medline), Scopus, and Web of Science databases to retrieve original, population-based studies with the universal GDM screening approach, published in English language and with a focus on adverse-maternal-outcomes up to January 2020. According to GDM diagnostic criteria, the studies were classified into seven groups. A total of 49 population-based studies consisting of 1409018 pregnant women with GDM and 7,667,546 non-GDM counterparts were selected for data analysis and knowledge synthesis. Accordingly, the risk of adverse-maternal-outcomes including primary-cesarean, induction of labor, maternal-hemorrhage, and pregnancy-related-hypertension, overall, regardless of GDM diagnostic-criteria and in all diagnostic-criteria subgroups were significantly higher than non-GDM counterparts. However, in meta-regression, the increased risk was not influenced by the GDM diagnostic-classification and the magnitude of the risks among patients, using the IADPSG criteria-classification as the most strict-criteria, was similar to other criteria. In conclusion, a reduction in the diagnostic-threshold increased the prevalence of GDM, but the risk of adverse-maternal-outcome was not different among those women who were diagnosed through more or less intensive strategies. Our review findings can empower health-care-providers to select the most cost-effective approach for the screening of GDM among pregnant women.


Author(s):  
Diego Barata Bandeira ◽  
Thaina Oliveira Felicio Olivatti ◽  
Fernanda Bolfi ◽  
Cesar Luiz Boguszewski ◽  
Vania dos Santos Nunes- Nogueira

Introduction: Although the association between acromegaly and pregnancy has been studied, recent evidence synthesis is lacking. Objective: To evaluate the association between acromegaly and pregnancy in terms of disease control and newborn/maternal outcomes. Methods: We will perform a systematic review according to Joanna Briggs Institute methodology for systematic reviews of etiology and risk. We will include studies with pregnant women, over 18 years old, diagnosed with acromegaly before or during the first trimester of pregnancy. Studies with pregnancy before acromegaly diagnosis will be excluded. We will consider cohort and case-control studies, and case series (at least 3 participants). Maternal primary outcomes will be acromegaly control, preterm birth, presence of diabetes, hypertension and/or eclampsia, and frequency of abortion. Newborn primary outcomes will be perinatal mortality and low birthweight. General and adaptive search strategies have been created for the Embase, Medline, LILACS, and CENTRAL databases. Two independent reviewers will assess eligibility of the studies, extract data, and evaluate their risk of bias. For dichotomous data, effect estimates will be calculated using relative risk with 95% confidence intervals (CIs). Continuous data will be expressed as means and standard deviation (SD) for each study, and the mean difference will be calculated with respective 95% CIs. For non-controlled studies, maternal outcomes will be compared pre- and postpartum, and for abortion frequency and newborn outcomes, we will perform proportional meta-analysis. Conclusion: We hope that the results of this review can help the management of pregnant women with acromegaly.


2020 ◽  
Author(s):  
Pengming Sun ◽  
Hangjing Gao ◽  
Xiqi Huang ◽  
Huanrui Zheng ◽  
Hongning Cai ◽  
...  

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yi-jie Gao ◽  
Lei Ye ◽  
Jia-shuo Zhang ◽  
Yang-xue Yin ◽  
Min Liu ◽  
...  

2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Angeline Jeyakumar ◽  
Vidhya Shinde ◽  
Reshma Ravindran

Abstract Background Vitamin D deficiency among pregnant women is a public health concern globally. In India, individual studies report high prevalence. However, lack of national data masks the true burden. This work determined the pooled prevalence of vitamin D deficiency among pregnant women in India through a systematic review of literature and meta-analysis. Methods Three different search engines yielded 15 eligible articles. Study quality was assessed by 10 different criteria and summary of study quality was categorized as per Cochrane standards. Meta-analysis was performed to estimate pooled prevalence of vitamin D deficiency among healthy pregnant women and heterogeneity among selected studies. A sample of n = 4088 was used to study the pooled prevalence among pregnant women. Results The random effects combined estimate was 32.35% (95% CI, (12.58–117.48). High heterogeneity (tau2 = 0.39, I2 = 100%) and high risk of bias was observed among the selected studies. The test for overall effect was observed to be z = 2.54(P = 0.01). Conclusion Pooled estimate > 30% emphasizes the need for screening through antenatal care services and initiate preventive measures to address the deficiency.


2021 ◽  
pp. 100952
Author(s):  
Nefsu Awoke ◽  
Tiwabwork Tekalign ◽  
Mistre Teshome ◽  
Tsegaye Lolaso ◽  
Getahun Dendir ◽  
...  

Author(s):  
Nadja A. Vielot ◽  
Christian E. Toval-Ruíz ◽  
Rachel Palmieri Weber ◽  
Sylvia Becker-Dreps ◽  
Teresa de Jesús Alemán Rivera

Author(s):  
Chiara Cerra ◽  
Roberta Morelli ◽  
Daniele Di Mascio ◽  
Danilo Buca ◽  
Francesca Di Sebastiano ◽  
...  

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