scholarly journals Considerations for conducting systematic reviews: evaluating the performance of different methods for de-duplicating references

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Sandra McKeown ◽  
Zuhaib M. Mir
Keyword(s):  
Systematic Reviews ◽  
False Positive ◽  
Evidence Synthesis ◽  
False Negative ◽  
Ease Of Use ◽  
Bibliographic Databases ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Central Register

Abstract Background Systematic reviews involve searching multiple bibliographic databases to identify eligible studies. As this type of evidence synthesis is increasingly pursued, the use of various electronic platforms can help researchers improve the efficiency and quality of their research. We examined the accuracy and efficiency of commonly used electronic methods for flagging and removing duplicate references during this process. Methods A heterogeneous sample of references was obtained by conducting a similar topical search in MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and PsycINFO databases. References were de-duplicated via manual abstraction to create a benchmark set. The default settings were then used in Ovid multifile search, EndNote desktop, Mendeley, Zotero, Covidence, and Rayyan to de-duplicate the sample of references independently. Using the benchmark set as reference, the number of false-negative and false-positive duplicate references for each method was identified, and accuracy, sensitivity, and specificity were determined. Results We found that the most accurate methods for identifying duplicate references were Ovid, Covidence, and Rayyan. Ovid and Covidence possessed the highest specificity for identifying duplicate references, while Rayyan demonstrated the highest sensitivity. Conclusion This study reveals the strengths and weaknesses of commonly used de-duplication methods and provides strategies for improving their performance to avoid unintentionally removing eligible studies and introducing bias into systematic reviews. Along with availability, ease-of-use, functionality, and capability, these findings are important to consider when researchers are selecting database platforms and supporting software programs for conducting systematic reviews.

scholarly journals Protetores de ouvido e olhos na promoção do sono em cuidados intensivos

2018 ◽  
Vol 12 (10) ◽  
pp. 2784 ◽  
Author(s):  
João Vitor Vieira ◽  
Rogério Ferrinho Ferreira ◽  
Margarida Palma Goes
Keyword(s):  
Intensive Care ◽  
Systematic Reviews ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Levels Of Evidence ◽  
Protective Devices ◽  
Quantitative Studies ◽  
Cochrane Database ◽  
Central Register

RESUMOObjetivo: analisar a contribuição dos protetores auriculares e das máscaras oculares para a promoção do sono do doente admitido em cuidados intensivos. Método: revisão integrativa da literatura que conduziu à pesquisa no motor de busca EBSCOHost, nas bases de dados CINAHL Complete, MEDLINE Complete, Cochrane Central Register of Controlled Trials e Cochrane Database of Systematic Reviews, para a identificação de estudos publicados entre 2014 e 2018. Foram selecionados quatro ensaios controlados randomizados. Esta revisão considerou a recomendação PRISMA. Os níveis de evidência foram assegurados pelos níveis de evidência do The Joanna Briggs Institute e a qualidade metodológica foi analisada com recurso ao Clinical Appraisal Skills Programme. Resultados: todos os artigos selecionados apontam para os benefícios da utilização desses dispositivos para a promoção da qualidade do sono do doente em cuidados intensivos. Conclusão: pela segurança e benefícios associados a esses dispositivos, sugere-se a sua utilização para a promoção da qualidade do sono do doente em cuidados intensivos. No entanto, pela escassez de estudos sobre o tema e pelas limitações dos estudos analisados, sugere-se a realização de mais estudos quantitativos com amostras mais representativas. Descritores: Protetores para Ouvido; Dispositivos de Proteção dos Olhos; Sono; Cuidados Críticos; Delírio.ABSTRACT Objective: to analyze the contribution of ear protectors and eye masks to promote the sleep of the patient admitted to intensive care. Method: integrative review of the literature that led to the search in the EBSCOHost search engine, in the databases CINAHL Complete, MEDLINE Complete, Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews, for the identification of studies published between 2014 and 2018. Four randomized controlled trials were selected. This review considered the PRISMA recommendation. Levels of evidence were secured by the levels of evidence from The Joanna Briggs Institute and methodological quality was analyzed using the Clinical Appraisal Skills Program. Results: all articles selected, point to the benefits of using these devices to promote the quality of sleep of the patient in intensive care. Conclusion: due to the safety and benefits associated with these devices, it is suggested that they be used to promote the quality of the patient's sleep in intensive care. However, due to the scarcity of studies on the subject and the limitations of the studies analyzed, it is suggested that more quantitative studies with more representative samples be carried out. Descritores: Ear Protective Devices; Eye Protective Devices; Sleep; Critical Care; Delirium.RESUMEN Objetivo: analizar la contribución de los protectores auriculares y de las máscaras oculares para la promoción del sueño del enfermo admitido en cuidados intensivos. Método: revisión integrativa de la literatura que condujo a la investigación en el motor de búsqueda EBSCOHost, en las bases de datos CINAHL Complete, MEDLINE Complete, Cochrane Central Register de Controlled Trials y Cochrane Database of Systematic Reviews, para la identificación de estudios publicados entre 2014 y 2018. Se seleccionaron cuatro ensayos controlados aleatorizados. Esta revisión consideró la recomendación PRISMA. Los niveles de evidencia fueron asegurados por los niveles de evidencia del The Joanna Briggs Institute y la calidad metodológica fue analizada con recurso al Clinical Appraisal Skills Programme. Resultados: todos los artículos seleccionados apuntan a los beneficios de la utilización de estos dispositivos para la promoción de la calidad del sueño del enfermo en cuidados intensivos. Conclusión: por la seguridad y los beneficios asociados a estos dispositivos, se sugiere su utilización para la promoción de la calidad del sueño del paciente en cuidados intensivos. Sin embargo, por la escasez de estudios sobre el tema y las limitaciones de los estudios analizados, se sugiere realizar más estudios cuantitativos con muestras más representativas. Descritores: Dispositivos de Protectores de Oídos; Dispositivos de Protección de los Ojos; Sueño; Cuidados Críticos; Delirio.

scholarly journals Efficacy and safety of atropine to control myopia progression: a systematic review and meta-analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Congling Zhao ◽  
Chunyan Cai ◽  
Qiang Ding ◽  
Hongbin Dai
Keyword(s):  
Meta Analysis ◽  
Optimal Dose ◽  
Control Group ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Myopia Progression ◽  
Central Register ◽  
Atropine Treatment ◽  
Observation Period

Abstract Background The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal dose is still unclear. Therefore, the purpose of this meta-analysis is to systematically evaluate the safety and effectiveness of atropine in controlling the progression of myopia, and to explore the relationship between the dose of atropine and the effectiveness of controlling the progression of myopia. Methods This work was done through the data searched from PubMed, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. The Cochrane Handbook was also used to evaluate the quality of the included studies. In addition, a meta-analysis was performed using Revman5.3 software. Results A total of 10 randomized controlled trials (RCTs) were included. Myopia progression was mitigated greater in the atropine treatment group than that in the control group, with MD = − 0.80, 95% CI (− 0.94, − 0.66) during the whole observation period. There was a statistical difference among 0.05, 0.5, and 1.0% atropine (P = 0.004). In addition, less axial elongation was shown, with MD = − 0.26, 95% CI (− 0.33, − 0.18) during the whole observation period. Conclusion The effectiveness of atropine in controlling the progression of myopia was dose related. A 0.05% atropine was likely to be the optimal dose.

scholarly journals The efficacy of psychotherapy, pharmacotherapy and their combination on functioning and quality of life in depression: a meta-analysis

2016 ◽  
Vol 47 (3) ◽  
pp. 414-425 ◽  
Author(s):  
K. Kamenov ◽  
C. Twomey ◽  
M. Cabello ◽  
A. M. Prina ◽  
J. L. Ayuso-Mateos
Keyword(s):  
Quality Of Life ◽  
Depressive Disorders ◽  
Meta Analysis ◽  
Combined Treatment ◽  
Effect Sizes ◽  
Controlled Trials ◽  
Depression Symptom ◽  
Cochrane Central Register ◽  
Central Register

BackgroundThere is growing recognition of the importance of both functioning and quality of life (QoL) outcomes in the treatment of depressive disorders, but the meta-analytic evidence is scarce. The objective of this meta-analysis of randomized controlled trials (RCTs) was to determine the absolute and relative effects of psychotherapy, pharmacotherapy and their combination on functioning and QoL in patients with depression.MethodOne hundred and fifty-three outcome trials involving 29 879 participants with depressive disorders were identified through database searches in Pubmed, PsycINFO and the Cochrane Central Register of Controlled Trials.ResultsCompared to control conditions, psychotherapy and pharmacotherapy yielded small to moderate effect sizes for functioning and QoL, ranging from g = 0.31 to g = 0.43. When compared directly, initial analysis yielded no evidence that one of them was superior. After adjusting for publication bias, psychotherapy was more efficacious than pharmacotherapy (g = 0.21) for QoL. The combination of psychotherapy and medication performed significantly better for both outcomes compared to each treatment alone yielding small effect sizes (g = 0.32 to g = 0.39). Both interventions improved depression symptom severity more than functioning and QoL.ConclusionDespite the small number of comparative trials for some of the analyses, this study reveals that combined treatment is superior, but psychotherapy and pharmacotherapy alone are also efficacious for improving functioning and QoL. The overall relatively modest effects suggest that future tailoring of therapies could be warranted to better meet the needs of individuals with functioning and QoL problems.

scholarly journals Efficacy and Safety of Atropine to Control Myopia Progression: A Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Congling Zhao ◽  
Chunyan Cai ◽  
Qiang Ding ◽  
Hongbin Dai
Keyword(s):  
Meta Analysis ◽  
Optimal Dose ◽  
Control Group ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Myopia Progression ◽  
Central Register ◽  
Atropine Treatment ◽  
Observation Period

Abstract Background: The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal effect dose is still unclear. Therefore, the purpose of this meta-analysis is to systematically evaluate the safety and effectiveness of atropine in controlling the progression of myopia, and to explore the relationship between the dose of atropine and the effect of controlling the progression of myopia. Methods: This work was done through the data search from PubMed, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. The Cochrane Handbook was also used to evaluate the quality of these included studies. In addition, a meta-analysis was performed using Revman5.3 software. Results: A total of 10 randomized controlled trials (RCTs) were included. Myopia progression was mitigated greater in the atropine treatment group than the control group, with MD = -0.80, 95% CI (-0.94, -0.66) during the whole observation period. There was a statistical difference between 0.05%, 0.5%, and 1.0% atropine (P = 0.004). In addition, less axial elongation was showed, with MD = -0.26, 95% CI (-0.33, -0.18) during the whole observation period. Conclusion: The effect of atropine in controlling the progression of myopia was dose related. A 0.05% atropine was likely to be the optimal dose.

scholarly journals Nonpharmacological Interventions to Improve Depression, Anxiety, and Quality of Life (QoL) in People With Dementia: An Overview of Systematic Reviews

2019 ◽  
Vol 33 (1) ◽  
pp. 28-41 ◽  
Author(s):  
Naoko Kishita ◽  
Tamara Backhouse ◽  
Eneida Mioshi
Keyword(s):  
Quality Of Life ◽  
Systematic Reviews ◽  
Cognitive Stimulation ◽  
Current Evidence ◽  
Future Research ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
People With Dementia ◽  
Current Evidence Base

This overview aimed to systematically synthesize evidence from existing systematic reviews to signpost practitioners to the current evidence base on nonpharmacological interventions to improve depression, anxiety, and quality of life (QoL) in people with dementia and to discuss priorities for future research. The databases MEDLINE, PsycINFO, Scopus, and Cochrane Central Register of Controlled Trials were searched in August 2017 with an updated search in January 2019. Fourteen systematic reviews of randomized controlled trials of nonpharmacological interventions were identified. Dementia stage was rated moderate or severe in the majority of the reviews and type of dementia varied. Interventions reported to be effective were cognitive stimulation (QoL: standardized mean difference [SMD] = 0.38), music-based therapeutic interventions (depression: SMD = −0.27, anxiety: SMD = −0.43, QoL: SMD = 0.32), and psychological treatments (mainly cognitive behavior therapy; depression: SMD = −0.22, anxiety: MD = −4.57). Although health-care professionals are recommended to continue using these approaches, future research needs to focus on the type and form of interventions that are most effective for different stages and types of dementia.

scholarly journals “Restauraciones de lesiones cervicales no cariosas: un protocolo de revisión sistemática para la práctica clínica”.

2018 ◽  
Vol 43 (2) ◽  
pp. 33-41
Author(s):  
Duniel Ricardo Ortuño Borroto ◽  
Beatriz Mellado ◽  
Sebastián Prado ◽  
Juan Pablo Vargas ◽  
Gabriel Rada
Keyword(s):  
Systematic Reviews ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Central Register ◽  
Revisión Sistemática ◽  
Meta Analyses

Introducción: Las lesiones cervicales no cariosas son condiciones patológicas no bacterianas localizadas en el límite amelocementario de los dientes. Los principales biomateriales descritos para el tratamiento restaurador de estas lesiones son: vidrios ionómeros, vidrios ionómeros modificados con resinas, compómeros y resinas compuestas. El objetivo de este protocolo, consiste en establecer los elementos metodológicos de una revisión sistemática que evaluará el comportamiento clínico de restauraciones cervicales realizadas con estos biomateriales. Métodos: El protocolo fue diseñado, y será reportado, en línea con Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P 2015). Se realizará una búsqueda sensible en MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials y ClinicalTrials.gov, sin restricción por lenguaje o publicación, para identificar ensayos controlados aleatorizados que comparen dos o más tratamientos restauradores en lesiones cervicales no cariosas. Los desenlaces a evaluar serán la retención de las restauraciones y caries secundaria, según criterios RYGE/USPHS. Al menos dos investigadores realizarán de manera independiente la selección de los ensayos y la extracción de los datos. El riesgo de sesgo será evaluado utilizando la herramienta recomendada por la colaboración Cochrane. Si es posible, se realizará un metanálisis y los datos serán presentados en tablas de resúmenes de resultados mediante el método Grading of Recommendations Assesment, Development and Evaluation (GRADE). Fortalezas y debilidades: Esta revisión sistemática entregará evidencia actualizada sobre el comportamiento de cuatro biomateriales en el tratamiento de lesiones cervicales no cariosas. La principal limitación proviene de la baja cantidad o deficiencias metodológicas de los estudios primarios. Número de registro (PROSPERO): CRD42017071114.

scholarly journals Buteyko method for people with asthma: a protocol for a systematic review and meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e049213
Author(s):  
Karla Morganna Pereira Pinto de Mendonça ◽  
Sean Collins ◽  
Tácito ZM Santos ◽  
Gabriela Chaves ◽  
Sarah Leite ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Meta Analysis ◽  
Secondary Data ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Plain Language ◽  
Randomised Controlled ◽  
Meta Analyses

IntroductionButeyko method is recommended as a non-pharmacological treatment for people with asthma. Although the worldwide interest in the Buteyko method, there is a paucity of studies gathering evidence to support its use. Therefore, we aim to conduct a systematic review and meta-analysis to assess the effects of the Buteyko method in children and adults with asthma.Methods and analysisWe will search on Cochrane Central Register of Controlled Trials, MEDLINE, Embase, US National Institutes of Health Ongoing Trials Register ClinicalTrials.gov and WHO International Clinical Trials Registry Platform for studies focusing on the Buteyko method for children and adults with asthma. The searches will be carried out in September 2021 from database’s inception to the present. We will include randomised controlled trials comparing Buteyko method alone with asthma education or inactive control intervention. There will be no restriction on language. Primary outcomes include quality of life, asthma symptoms and adverse events/side effects. Two review authors will independently screen the studies for inclusion and extract data. We will assess the quality of the included studies using the ‘Risk of Bias’ tool. The certainty of the evidence will be assessed using the GRADE approach. Data synthesis will be conducted using Review Manager software. Reporting of the review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance and the Cochrane Handbook for Systematic Reviews of Interventions.Ethics and disseminationThis study will assess and provide evidence for the use of the Buteyko method in people with asthma. We will analyse secondary data and this does not require ethics approval. The findings will be published in peer-reviewed journals, at relevant conferences and will be shared in plain language in social media. Moreover, the findings of this review could guide the direction of healthcare practice and research.PROSPERO registration numberCRD42020193132.

scholarly journals Efficacy and Safety of Specific Immunotherapy with Aeroallergens in the Management of Atopic Dermatitis: A Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Cita Rosita Sigit Prakoeswa ◽  
Sylvia Anggraeni ◽  
Damayanti Damayanti ◽  
Menul Ayu Umborowati ◽  
Cintya Dipta Riswanto ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Specific Immunotherapy ◽  
Meta Analysis ◽  
Placebo Control ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Efficacy And Safety ◽  
Central Register ◽  
And Gender

Abstract Background: Specific immunotherapy with standardized aeroallergens can reduce symptoms and increase the quality of life for related allergy patients. This therapy is still controversial for atopic dermatitis (AD). Hence, a meta-analysis to assess efficacy and safety of specific immunotherapy with aeroallergens on patients with AD could provide a clear oversight on advantages and limitations of such treatment.Methods: We systematically searched PubMed, DOAJ, and Cochrane Central Register of Controlled Trials databases for relevant studies published Randomized controlled trials (RCTs) up to October 2020. Studies involving all ages and gender with AD who treated with specific immunotherapy employing aeroallergens compared with placebo/control.Results: Seven studies RCTs were identified with 832 participants. Significantly decreased of SCORAD values favoring immunotherapy were observed (MD: -5.42; 95% CI - 10.31, -0.52; p=0.03). VAS score was significantly decrease (MD: -1.21; 95% CI -2.10, -0.31; p=0.008). However, immunotherapy showed no significant local and systemic adverse events ((RR 1.77; 95% CI 0.98, 3.19, p=0.06); (RR 0.69; 95% CI 0.16, 3.01, p=0.62)) and IgG4 Dermatophagoides farinae (MD: 92.36, 95% CI -89.14,273.87; p=0.32). Conclusion: Our five years meta-analysis included small number studies, indicated moderate-level evidence for immunotherapy with standardized extract of aeroallergens is effective and safe for AD patients.

scholarly journals Efficacy and Safety of Atropine to Control Myopia Progression: A Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Congling Zhao ◽  
Chunyan Cai ◽  
Qiang Ding ◽  
Hongbin Dai
Keyword(s):  
Meta Analysis ◽  
Optimal Dose ◽  
Control Group ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Myopia Progression ◽  
Central Register ◽  
Atropine Treatment ◽  
Observation Period

Abstract Background: The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal effect dose is still unclear. Therefore, the purpose of this meta-analysis is to systematically evaluate the safety and effectiveness of atropine in controlling the progression of myopia, and to explore the relationship between the dose of atropine and the effect of controlling the progression of myopia. Methods: This work was done through the data search from PubMed, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. The Cochrane Handbook was also used to evaluate the quality of these included studies. In addition, a meta-analysis was performed using Revman5.3 software. Results: A total of 10 randomized controlled trials (RCTs) were included. Myopia progression was mitigated greater in the atropine treatment group than the control group, with MD = -0.80, 95% CI (-0.94, -0.66) during the whole observation period. There was a statistical difference between 0.05%, 0.5%, and 1.0% atropine (P = 0.004). In addition, less axial elongation was showed, with MD = -0.26, 95% CI (-0.33, -0.18) during the whole observation period. Conclusion: The effect of atropine in controlling the progression of myopia was dose related. A 0.05% atropine was likely to be the optimal dose.

scholarly journals Does Acupuncture Improve Quality of Life for Patients with Pain Associated with the Spine? A Systematic Review

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Shao-chen Lu ◽  
Zhen Zheng ◽  
Charlie Changli Xue
Keyword(s):  
Physical Functioning ◽  
Waiting List ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Mental Functioning ◽  
Short Term ◽  
Point Selection ◽  
Central Register ◽  
Better Than

This paper aimed to evaluate the effectiveness of acupuncture for qualities of life (QoL) in patients suffering from pain associated with the spine (PAWS). Acupuncture has been shown to reduce pain severity, but its effect on QoL is unknown. PubMed, CINAHL, and Cochrane Central Register of Controlled Trials as well as EMBASE were searched. Published randomized controlled trials on PAWS comparing acupuncture with waiting-list or sham interventions were considered. Eight out of 186 trials were included. For physical functioning, acupuncture was better than waiting-list at immediate and short-term followups; and was better than sham interventions at immediate assessment (SMD = 0.40. 95% CI 0.06 to 0.74). For mental functioning, acupuncture was better than waiting-list at short-term followup and sham interventions at intermediate-term followup (SMD = 0.27. 95% CI 0.03 to 0.51). A similar effect was observed on pain reduction. Discrepancies in point selection for relieving anxiety and insufficient training of trial acupuncturists were also identified. Acupuncture has a moderate effect on the improvement of physical functioning and pain for PAWS patients in the short term; but the effect for mental functioning is small and delayed. Future trials should address point selection and consistency in the qualifications of trial acupuncturists.

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