scholarly journals Recovery effect of lignans and fermented extracts from Forsythia koreana flowers on pancreatic islets damaged by alloxan in zebrafish (Danio rerio)

2019 ◽  
Vol 62 (1) ◽  
Author(s):  
Yeong-Geun Lee ◽  
Isabel Rodriguez ◽  
Youn Hee Nam ◽  
Jung Eun Gwag ◽  
Sang Ho Woo ◽  
...  
Keyword(s):  
Pancreatic Islets ◽  
Danio Rerio ◽  
Recovery Effect ◽  
Forsythia Koreana

Recovery Effect of a Rutin-Enriched Fraction Prepared From Forsythia koreana Flowers on Alloxan-Induced Pancreatic Islets in Zebrafish Larvae (Danio rerio)

2021 ◽  
Vol 16 (10) ◽  
pp. 1934578X2110437
Author(s):  
Yeong-Geun Lee ◽  
Youn Hee Nam ◽  
Jung Eun Gwag ◽  
Jung-Hwan Ko ◽  
Kyeong-Hwa Seo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Pancreatic Islets ◽  
Danio Rerio ◽  
Spectroscopic Data ◽  
Recovery Effect ◽  
Meoh Extract ◽  
Simple Method ◽  
Zebrafish Larvae ◽  
Forsythia Koreana ◽  
First Time

A simple method to prepare a high-content rutin fraction from Forsythia koreana flowers (HRFK) is described. Rutin, isolated for the first time from the flowers, was identified from spectroscopic data including nuclear magnetic resonance, mass spectrometry, and infrared. As a result of HPLC quantitative analysis, the content of rutin was found to be 80.0 ± 0.02% in HRFK. Our previous study reported that F koreana MeOH extract (FK) significantly recovered alloxan-induced pancreatic islets in zebrafish. However, HRFK as well as rutin exhibited an enhanced anti-diabetic effect compared to FK in our latest experiments. In conclusion, HRFK, as well as rutin and FK, have potential as anti-diabetic agents.

Recovery effect of phenylpropanoid glycosides from Magnolia obovata fruit on alloxan-induced pancreatic islet damage in zebrafish ( Danio rerio )

2015 ◽  
Vol 416 ◽  
pp. 70-74 ◽  
Author(s):  
Kyeong-Hwa Seo ◽  
Youn-Hee Nam ◽  
Dae-Young Lee ◽  
Eun-Mi Ahn ◽  
Tong-Ho Kang ◽  
...  
Keyword(s):  
Pancreatic Islet ◽  
Danio Rerio ◽  
Recovery Effect ◽  
Magnolia Obovata ◽  
Phenylpropanoid Glycosides

Plasmalemma localisation of inorganic phosphate in B cells pancreas

1978 ◽  
Vol 36 (2) ◽  
pp. 528-529
Author(s):  
F. B. P. Wooding ◽  
K. Pedley ◽  
N. Freinkel ◽  
R. M. C. Dawson
Keyword(s):  
Electron Microscope ◽  
B Cells ◽  
B Cell ◽  
Pancreatic Islets ◽  
High Glucose ◽  
Lead Acetate ◽  
Inorganic Phosphate ◽  
Slight Modification ◽  
Uranyl Acetate ◽  
Lead Phosphate

Freinkel et al (1974) demonstrated that isolated perifused rat pancreatic islets reproduceably release up to 50% of their total inorganic phosphate when the concentration of glucose in the perifusion medium is raised.Using a slight modification of the Libanati and Tandler (1969) method for localising inorganic phosphate by fixation-precipitation with glutaraldehyde-lead acetate we can demonstrate there is a significant deposition of lead phosphate (identified by energy dispersive electron microscope microanalysis) at or on the plasmalemma of the B cell of the islets (Fig 1, 3). Islets after incubation in high glucose show very little precipitate at this or any other site (Fig 2). At higher magnification the precipitate seems to be intracellular (Fig 4) but since any use of osmium or uranyl acetate to increase membrane contrast removes the precipitate of lead phosphate it has not been possible to verify this as yet.

Local interaction rules and collective motion in black neon tetra (Hyphessobrycon herbertaxelrodi) and zebrafish (Danio rerio).

2019 ◽  
Vol 133 (2) ◽  
pp. 143-155 ◽  
Author(s):  
Vicenç Quera ◽  
Elisabet Gimeno ◽  
Francesc S. Beltran ◽  
Ruth Dolado
Keyword(s):  
Danio Rerio ◽  
Collective Motion ◽  
Local Interaction

IONIC EFFECTS ON THE UPTAKE OF CHLOROMERCURIBENZENE-p-SULPHONIC ACID BY PANCREATIC ISLETS

1977 ◽  
Vol 86 (3) ◽  
pp. 552-560 ◽  
Author(s):  
Monica Söderberg ◽  
Inge-Bert Täljedal
Keyword(s):  
Pancreatic Islets ◽  
Islet Cell ◽  
Choline Chloride ◽  
Inorganic Ions ◽  
Sulphonic Acid ◽  
Cell Uptake ◽  
Β Cells ◽  
Sulphydryl Groups ◽  
Microdissected Pancreatic Islets ◽  
Ionic Effects

ABSTRACT Effects of inorganic ions on the uptake of chloromercuribenzene-p-sulphonic acid (CMBS) were studied in microdissected pancreatic islets of non-inbred ob/ob-mice. Na2SO4 stimulated the total islet cell uptake of CMBS but decreased the amount of CMBS remaining in islets after brief washing with L-cysteine. CaCl2 stimulated both the total and the cysteine-non-displaceable uptake; the stimulatory effect of CaCl2 on the cysteine-non-displaceable CMBS uptake was counteracted by Na2SO4. NaCl, KCl or choline chloride had no significant effect on the total islet cell uptake of CMBS, whereas LiCl was stimulatory. It is concluded that β-cells resemble erythrocytes in having a permeation path for CMBS that is inhibited by SO42−. By analogy with existing models of the erythrocyte membrane, it is suggested that the SO42−-sensitive path leads to sulphydryl groups controlling monovalent cationic permeability in β-cells.

Genetic Effects on Enhancer Activity in Human Pancreatic Islets

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1706-P ◽  
Author(s):  
ARUSHI VARSHNEY ◽  
STEPHEN PARKER ◽  
Keyword(s):  
Pancreatic Islets ◽  
Genetic Effects ◽  
Enhancer Activity ◽  
Human Pancreatic Islets
Sign in / Sign up

Export Citation Format

Share Document