scholarly journals Free-breathing radial 3D fat-suppressed T1-weighted gradient echo (r-VIBE) sequence for assessment of pulmonary lesions: a prospective comparison of CT and MRI

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nan Yu ◽  
Haifeng Duan ◽  
Chuangbo Yang ◽  
Yong Yu ◽  
Shan Dang

Abstract Purpose To determine whether the pulmonary MR imaging with free-breathing radial 3D fat-suppressed T1-weighted gradient echo (r-VIBE) sequence can detect lung lesions and display lesion profiles with an accuracy comparable to that of computed tomography (CT), which is the reference standard in this study. Population Sixty-three consecutive patients were prospectively enrolled between October, 2016 and March, 2017. All the patients received both 3T MRI scanning with a free-breathing r-VIBE sequence and chest standard CT. Morphologic features of lesions were evaluated by two radiologists with a 5-point system. Chest standard CT were used as reference standard. Weighted kappa analysis and chi-squared test were used to determine both inter-observer agreement and inter-method agreement. Results A total of 210 solid pulmonary nodules or masses and 1 ground-glass nodule were detected by CT. Compared to CT, r-VIBE correctly detected 95.7% of pulmonary nodules, including 100% of detection rate with diameter greater than 6 mm, 92.3% of pulmonary nodules with diameter between 4 and 6 mm, and 83.3% of pulmonary nodules with diameter less than 4 mm The inter-method agreements between r-VIBE and standard-dose CT were either “substantial” or “excellent” in the evaluation of following features of pulmonary nodules with diameter more than 10mm: including lobulation, spiculation, convergence of vessels, bubble-like attenuation, cavitation and mediastinal lymph node enlargement (0.605≤K≤1.000; P<0.0001). However, K values for inter-method agreements were significant but “moderate” or “poor” for evaluating pleural tag, halo, and calcification (0.355≤ K≤0.451; P<0.0001). Conclusion The use of pulmonary MR imaging with r-VIBE showed high detection rate of pulmonary nodules and inter-method agreement with CT. It is also useful for nodule morphologic assessment.

PLoS ONE ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. e0156272 ◽  
Author(s):  
Andrzej Cieszanowski ◽  
Antonina Lisowska ◽  
Marta Dabrowska ◽  
Piotr Korczynski ◽  
Malgorzata Zukowska ◽  
...  

2002 ◽  
Vol 43 (5) ◽  
pp. 464-473
Author(s):  
M. Alemany Ripoll ◽  
R. Raininko

Purpose: To compare the detectability of small experimental intracranial haemorrhages on MR imaging at 0.5 T and 1.5 T, from hyperacute to subacute stages. Material and Methods: 1 ml of autologous blood was injected into the brain of 15 rabbits to create intraparenchymal haematomas. Since the blood partially escaped into the cerebrospinal fluid (CSF) spaces, detectability of subarachnoid and intraventricular blood was also evaluated. MR imaging at 0.5 T and at 1.5 T was repeated up to 14 days, including T1-, proton density- and T2-weighted (w) spin-echo (SE), FLAIR and T2*-w gradient echo (GE) pulse sequences. The last MR investigation was compared to the formalin-fixed brain sections in 7 animals. Results: The intraparenchymal haematomas were best revealed with T2*-w GE sequences, with 100% of sensitivity at 1.5 T and 90–95% at 0.5 T. Blood in the CSF spaces was significantly ( p < 0.05) better detected at 1.5 T with T2*-w GE sequences and detected best during the first 2 days. The next most sensitive sequence for intracranial blood was FLAIR. SE sequences were rather insensitive. Conclusion: 1.5 T equipment is superior to 0.5 T in the detection of intracranial haemorrhages from acute to subacute stages. T2*-w GE sequences account for this result but other sequences are also needed for a complete examination.


Radiology ◽  
2014 ◽  
Vol 272 (2) ◽  
pp. 397-406 ◽  
Author(s):  
Hsin-Jung Yang ◽  
Roya Yumul ◽  
Richard Tang ◽  
Ivan Cokic ◽  
Michael Klein ◽  
...  

2017 ◽  
Vol 59 (5) ◽  
pp. 627-634 ◽  
Author(s):  
Sungmin Woo ◽  
Sang Youn Kim ◽  
Jeong Yeon Cho ◽  
Seung Hyup Kim

Background Recent literature suggests that intratumoral hemorrhage detection may be helpful in differentiating papillary renal cell carcinoma (pRCC) from fat-poor angiomyolipoma (fpAML). Purpose To determine whether intratumoral hemorrhage detected using chemical shift magnetic resonance imaging (MRI) and T2*-weighted (T2*W) gradient echo (GRE) can be used to differentiate pRCC from fpAML. Material and Methods This retrospective study included 42 patients with pRCC (n = 28) and fpAML (n = 14) who underwent MRI followed by surgery. Two blinded radiologists independently assessed the presence of intratumoral hemorrhage using chemical shift MRI (decrease in signal intensity from opposed- to in-phase) and T2*W GRE (“blooming”). Consensus reading was determined for discrepant cases. MRI findings were compared using Chi-square test. Inter-observer agreement was assessed using kappa statistics. Results Inter-observer agreement was substantial for both sequences ( k = 0.622 and 0.793, P < 0.001). For chemical shift MRI, the prevalence of intratumoral hemorrhage was significantly greater in pRCC than in fpAML (71.4% versus 28.6%, P = 0.019 for reader 1; 64.3% versus 14.3%, P = 0.003 for reader 2; and 75% versus 21.4%, P = 0.002 for the consensus). T2*W GRE showed a similar tendency (46.4% versus 14.3%, P = 0.049 for both readers; and 50% versus 14.3%, P = 0.042 for the consensus). Using the consensus reading, sensitivity and specificity of determining pRCC were 75% and 78.6% for chemical shift MRI and 50% and 85.7% for T2*W GRE. Conclusion The prevalence of intratumoral hemorrhage identified from chemical shift MRI or T2*W GRE was significantly different between pRCC and fpAML. These hemorrhage-sensitive MRI sequences may be used as an adjunctive tool for discriminating between the two entities.


2006 ◽  
Vol 23 (3) ◽  
pp. 339-344 ◽  
Author(s):  
Kengo Yoshimitsu ◽  
Daisuke Kakihara ◽  
Hiroyuki Irie ◽  
Tsuyoshi Tajima ◽  
Akihiro Nishie ◽  
...  

1998 ◽  
Vol 39 (2) ◽  
pp. 161-166
Author(s):  
A. Sundin ◽  
C. Wang ◽  
A. Ericsson ◽  
A.-K. Fahlvik

Purpose: to evaluate reticular endothelial system-specific magnetic starch microspheres (MSM) as an i.v. contrast agent for MR imaging in a model of experimental liver metastases Material and Methods: the study comprised 15 nude rats, 7 of which were carrying hepatic metastases from a human colonic cancer. the 15 rats were examined at 0.5 T using a T1-weighted spin-echo (SE) sequence and a gradientecho sequence. the examinations were performed before and 15 min after the administration of accumulated doses of MSM at 0.25–2.5 mg Fe/kg b.w. the images were compared with corresponding serial liver specimens Results: A loss of liver signal intensity was obtained at all MSM dose levels. No metastases were detected in the pre-contrast images. the optimum detection rate of hepatic metastases was reached with the SE sequence at a dose of 1.0 mg Fe/kg b.w. MSM and the diameters of the smallest lesions depicted were 1 mm. However, in the SE sequence, the measured lesion-to-liver contrast and liver signal damping were highest at the largest dose, indicating a possible image degrading effect of MSM at high doses. Administration of MSM as a short bolus over 30 s resulted in congestion of the liver with dilatation of the hepatic veins. When MSM was instead injected slowly over 5 min, this adverse effect was not seen Conclusion: the use of MSM dramatically increased the detection of experimental hepatic metastases


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