Correlation of sexual dysfunction and brain magnetic resonance imaging in multiple sclerosis

2003 ◽  
Vol 9 (1) ◽  
pp. 108-110 ◽  
Author(s):  
M Zorzon ◽  
R Zivadinov ◽  
L Locatelli ◽  
B Stival ◽  
D Nasuelli ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Sexual Dysfunction ◽  
Bladder Dysfunction ◽  
Resonance Imaging ◽  
Whole Brain ◽  
Total Brain ◽  
Significant Difference ◽  
The Brain

Sixty-two patients (40 women and 22 men) with multiple sclerosis (MS) were examined with 1.5 tesla magnetic resonance imaging (MRI) of the brain. Information on sexual and sphincteric disturbances has been collected, and data on disability, independence, cognitive performances and psychological functioning have been assessed. C alculations of T1- and T2-lesion load (LL) of total brain, frontal lobes and pons have been performed using a reproducible semiautomated technique. Whole brain, frontal and pontine atrophies were estimated using a normalized measure, the brain parenchymal fraction (BPF), obtained with a computerized interactive program. When comparing patients with and without sexual dysfunction (SD), there were no differences in total brain, frontal and pontine T1- and T2-LL, as well as in measures of whole brain and frontal atrophy. The only significant difference was in the pontine BPF (P-0.026). In linear multiple regression analysis, SD was associated with depression (R-0.56, P-0.001) and, after adjusting for depression and anxiety, with bladder dysfunction (R-0.43, P-0.003) and pontine BPF (R-0.56, P-0.001). No association between SD and any of the measures of T1- and T2-LL was found. The findings showed a relationship between SD and pontine atrophy, confirmed the correlation of SD with bladder dysfunction and highlighted the role of psychological factors in determining SD.

NUCLEAR MAGNETIC RESONANCE IMAGING OF THE BRAIN IN MULTIPLE SCLEROSIS

The Lancet ◽  
1981 ◽  
Vol 318 (8255) ◽  
pp. 1063-1066 ◽  
Author(s):  
I.R Young ◽  
A.S Hall ◽  
C.A Pallis ◽  
G.M Bydder ◽  
N.J Legg ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Nuclear Magnetic Resonance Imaging ◽  
Resonance Imaging ◽  
The Brain ◽  
Nuclear Magnetic

Application of Artificial Intelligence in Magnetic Resonance Imaging to reduce Gadolinium accumulation in patients with multiple sclerosis: A Review

2021 ◽  
Vol 1 (4) ◽  
pp. 416-428
Author(s):  
Vijay Anant Athavale ◽  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Artificial Intelligence ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Mri Scans ◽  
The Central Nervous System ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain ◽  
New Onset

Gadolinium (Gd) is a based contrast agent is used for Magnetic Resonance Imaging (MRI). In India, gadobutrolhas been is approved for MRI of the Central Nervous System (CNS), liver, kidneys, and breast. It has been noted in several studies that the accumulation of gadolinium occurs in different structures in the brain. Patients with Multiple Sclerosis (MS) are regularly followed up with MRI scans and MRI with contrast enhancement is the most common method of distinguishing new-onset pathological changes. Developments in technology and methods in artificial intelligence have shown that there is reason to map out the X-ray technician’s work with examinations and medicines administered to patients may be altered to prevent the accumulation of gadolinium.

scholarly journals Diffusion Tensor Magnetic Resonance Imaging in Patients with Multiple Sclerosis and its Relationship with Disability

2013 ◽  
Vol 26 (1) ◽  
pp. 3-17 ◽  
Author(s):  
Ş. Temel ◽  
H.D. Kekliğkoğlu ◽  
G. Vural ◽  
O. Deniz ◽  
K. Ercan
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
White Matter ◽  
Magnetic Resonance ◽  
Diffusion Tensor ◽  
Water Diffusion ◽  
Control Group ◽  
Healthy Individuals ◽  
Resonance Imaging ◽  
Significant Difference

Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. Diffusion tensor magnetic resonance imaging (DTI) can yield important information on the in vivo pathological processes affecting water diffusion. The aim of this study was to quantitatively define water diffusion in normal-appearing white matter (NAWM) distant from the plaque, in the plaque, and around the plaque, and to investigate the correlation of these changes with clinical disability. Conventional MRI and DTI scans were conducted in 30 patients with MS and 15 healthy individuals. Fractional anisotropy maps and visible diffusion coefficients were created and integrated with T2-weighted images. Regions of interest (ROIs) were placed on the plaques on the same side, white matter around the plaques and NAWM on the opposite side. Only the white matter of healthy individuals in the control group, and FA and ADC values were obtained for comparison. The highest FA and lowest ADC were detected in the control group at the periventricular region, cerebellar peduncle and at all ROIs irrespective of location. There was a significant difference in comparison to the control group at all ROIs in patients with MS (p < 0.001 for all comparisons). No significant correlation between diffusion parameters and expanded disability state scale (EDSS) scores was found in patients with MS. DTI may provide more accurate information on the damage due to the illness, compared to T2A sequences, but this damage may not be correlated with the clinical disability measured by EDSS score.

Resolution-dependent estimates of lesion volumes in magnetic resonance imaging studies of the brain in multiple sclerosis

1995 ◽  
Vol 38 (5) ◽  
pp. 749-754 ◽  
Author(s):  
M. Filippi ◽  
M. A. Horsfield ◽  
A. Campi ◽  
S. Mammi ◽  
C. Pereira ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Imaging Studies ◽  
The Brain

scholarly journals Imaging Multiple Sclerosis Pathology at 160μm Isotropic Resolution by Human Whole-Brain Ex Vivo Magnetic Resonance Imaging at 3T

2021 ◽  
Author(s):  
Weigel Matthias ◽  
Dechent Peter ◽  
Galbusera Riccardo ◽  
Bahn Erik ◽  
Nair Govind ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Ex Vivo ◽  
Molecular Layer ◽  
Cortical Lesion ◽  
Resonance Imaging ◽  
Whole Brain

AbstractPostmortem magnetic resonance imaging (MRI) of the fixed healthy and diseased human brain facilitates spatial resolutions and image quality that is not achievable with in vivo MRI scans. Though challenging - and almost exclusively performed at 7T field strength - depicting the tissue architecture of the entire brain in fine detail is invaluable since it enables the study of neuroanatomy and uncovers important pathological features in neurological disorders. The objectives of the present work were (i) to develop a 3D isotropic ultra-high-resolution imaging approach for human whole-brain ex vivo acquisitions working on a standard clinical 3T MRI system, and (ii) to explore the sensitivity and specificity of this concept for specific pathoanatomical features of multiple sclerosis. The reconstructed images demonstrate unprecedented resolution and soft tissue contrast of the diseased human brain at 3T, thus allowing visualization of sub-millimetric lesions in the different cortical layers and in the cerebellar cortex, as well as unique cortical lesion characteristics such as the presence of incomplete / complete iron rims, and patterns of iron accumulation. Further details such as the subpial molecular layer, the line of Gennari, and some intrathalamic nuclei are also well distinguishable.

scholarly journals Distribution of multiple sclerosis lesions detected by brain magnetic resonance imaging in Erbil city

2021 ◽  
Vol 25 (1) ◽  
pp. 446-455
Author(s):  
Dina Tawfeeq ◽  
Shawnam Dawood
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Corpus Callosum ◽  
Brain Stem ◽  
Signal Intensity ◽  
Brain Regions ◽  
Multiple Sclerosis Lesion ◽  
Resonance Imaging ◽  
The Brain

Background and objective: Many epidemiological studies and clinical manifestation studies of multiple sclerosis have been done in Iraq. Up to our knowledge, no such observational study to the radiological feature of the multiple sclerosis lesion has been done yet in Erbil in comparison to other worldwide studies. This study aimed to assess the distribution of multiple sclerosis lesions in brain regions detected by magnetic resonance imaging among Erbil population. Methods: This was a cross-sectional study conducted at the College of Medicine, Hawler Medical University, from April 2018 to July 2019. A review of magnetic resonance imaging scans of the brain of 120 patients was done. Special attention was directed toward identifying the variance in multiple sclerosis lesions distribution in the brain regions and their MR signal intensity characteristics. Results: Periventricular lesions were observed in more than 90% of the study sample. The next common was juxtacortical lesions (24.8%), followed by corpus callosum lesions (16.8 %), while brain stem lesions were the least observed proportions. No significant difference was detected in the distribution of multiple sclerosis lesions among ethnicities and genders, except for basal ganglia lesions, which were significantly more common in women (P = 0.016).The magnetic resonance imaging signal intensity of the lesion was significantly variable among disease duration. Conclusion: The T2 hyper intense lesions were most commonly seen in the periventricular region. Juxtacortical and corpus callosum lesions were also frequently observed. The proportions of the brain stem and cerebellum lesions appeared to be lower in comparison to previous studies. Keywords: Multiple Sclerosis; Magnetic Resonance Imaging; Distribution; Lesion.

scholarly journals Comparison of MRT-research materials of brain in multiple sclerosis and lupus erythematosus

2008 ◽  
Vol 7 (5-1) ◽  
pp. 228-230
Author(s):  
Yu. N. Lisitsyna ◽  
V. M. Alifirova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Lupus Erythematosus ◽  
Differential Diagnostics ◽  
Resonance Imaging ◽  
Specific Sign ◽  
The Brain

It appears that sometimes it is difficult to perform differential diagnostics of multiple sclerosis and autoimmune illness. 29 patients were surveyed with lupus erythematosus and 29 patients hue suffer from multiple sclerosis. Here are presented our own results of magnetic resonance imaging of the brain of there patients. It is discovered that existence of nidus of T2 signal increase doesn’t appear to be a specific sign.

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