Socratic questioning put into clinical practice

2020 ◽  
pp. 1-3
Author(s):  
Carlos Carona ◽  
Charlotte Handford ◽  
Ana Fonseca
Keyword(s):  
Clinical Practice ◽  
Clinical Applications ◽  
Behavioural Medicine ◽  
Clinical Communication ◽  
The Core ◽  
Socratic Questioning ◽  
Recent Developments

SUMMARY Socratic questioning is at the core of collaborative clinical communication, with a wide array of applications in behavioural medicine and psychotherapy. This brief article describes the process of therapeutic Socratic questioning, illustrates its clinical applications in therapy and provides a brief update on its recent developments.

The Primacy of Experience

2019 ◽  
pp. 64-81
Author(s):  
Andrea Schiavio
Keyword(s):  
Ecological Factors ◽  
Assessment Practices ◽  
Flexible Systems ◽  
Phenomenological Philosophy ◽  
The Core ◽  
Learning Contexts ◽  
Grading Systems ◽  
Recent Developments ◽  
Core Issue ◽  
Event Based

This chapter explores a possible alternative to traditional “paper-and-pencil” assessment practices in music classes. It argues that an approach based on phenomenological philosophy and inspired by recent developments in cognitive science may shed new light on learning and help educators reconsider grading systems accordingly. After individuating the core issue in an unresolved tension between subjective-objective methodologies relevant to certain learning contexts, the chapter proposes a possible remedy by appealing to three principles central to “embodied” approaches to cognition. Such principles may help educators reframe cognitive phenomena (learning described as a measurable event based on “information processing”) in terms of cognitive ecosystems (learning understood as a negotiating and transformative activity codetermined by diverse embodied and ecological factors connected in recurrent fashion). Accommodating this shift implies transforming assessment practices into more open and flexible systems that take seriously the challenge of cooperative learning and phenomenological reflections.

scholarly journals CASTING THE LIGHT OF THE THEORY OF OPPOSITION ONTO HOHFELD'S FUNDAMENTAL LEGAL CONCEPTS

Legal Theory ◽  
2021 ◽  
pp. 1-34
Author(s):  
João Alberto de Oliveira Lima ◽  
Cristine Griffo ◽  
João Paulo A. Almeida ◽  
Giancarlo Guizzardi ◽  
Marcio Iorio Aranha
Keyword(s):  
Conceptual Framework ◽  
Legal Theory ◽  
Analytical Framework ◽  
The Core ◽  
Recent Developments ◽  
The Law ◽  
Opposition Theory ◽  
Legal Concepts ◽  
Number Of Authors

Abstract At the core of Hohfeld's contribution to legal theory is a conceptual framework for the analysis of the legal positions occupied by agents in intersubjective legal relations. Hohfeld presented a system of eight “fundamental” concepts relying on notions of opposition and correlation. Throughout the years, a number of authors have followed Hohfeld in applying the notion of opposition to analyze legal concepts. Many of these authors have accounted for Hohfeld's theory in direct analogy with the standard deontic hexagon. This paper reviews some of these accounts and extends them employing recent developments from opposition theory. In particular, we are able to extend application of opposition theory to an open conception of the law. We also account for the implications of abandoning the assumption of conflict-freedom and admitting seemingly conflicting legal positions. This enables a fuller analysis of Hohfeld's conceptual analytical framework. We also offer a novel analysis of Hohfeld's power positions.

scholarly journals Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Ângela C. B. Neves ◽  
Ivanna Hrynchak ◽  
Inês Fonseca ◽  
Vítor H. P. Alves ◽  
Mariette M. Pereira ◽  
...  
Keyword(s):  
Large Scale ◽  
Neuroendocrine Tumours ◽  
Radiochemical Yield ◽  
Clinical Applications ◽  
Clinical Use ◽  
Molar Activity ◽  
Neuropsychiatric Diseases ◽  
Recent Developments ◽  
Key Issues ◽  
Improved Methods

AbstractThe neurotracer 6-[18F] FDOPA has been, for many years, a powerful tool in PET imaging of neuropsychiatric diseases, movement disorders and brain malignancies. More recently, it also demonstrated good results in the diagnosis of other malignancies such as neuroendocrine tumours, pheochromocytoma or pancreatic adenocarcinoma.The multiple clinical applications of this tracer fostered a very strong interest in the development of new and improved methods for its radiosynthesis. The no-carrier-added nucleophilic 18F-fluorination process has gained increasing attention, in recent years, due to the high molar activities obtained, when compared with the other methods although the radiochemical yield remains low (17–30%). This led to the development of several nucleophilic synthetic processes in order to obtain the product with molar activity, radiochemical yield and enantiomeric purity suitable for human PET studies.Automation of the synthetic processes is crucial for routine clinical use and compliance with GMP requirements. Nevertheless, the complexity of the synthesis makes the production challenging, increasing the chance of failure in routine production. Thus, for large-scale clinical application and wider use of this radiopharmaceutical, progress in the automation of this complex radiosynthesis is of critical importance.This review summarizes the most recent developments of 6-[18F]FDOPA radiosynthesis and discusses the key issues regarding its automation for routine clinical use.

scholarly journals Recent Developments in Clinical Applications of Mesenchymal Stem Cells in the Treatment of Rheumatoid Arthritis and Osteoarthritis

2021 ◽  
Vol 12 ◽  
Author(s):  
Joel Jihwan Hwang ◽  
Yeri Alice Rim ◽  
Yoojun Nam ◽  
Ji Hyeon Ju
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Trials ◽  
Clinical Applications ◽  
Clinical Settings ◽  
Positive Outcomes ◽  
Joint Function ◽  
Safety And Efficacy ◽  
High Expectations ◽  
Recent Developments

Mesenchymal stem cell (MSC) therapies have been used as cell-based treatments for decades, owing to their anti-inflammatory, immunomodulatory, and regenerative properties. With high expectations, many ongoing clinical trials are investigating the safety and efficacy of MSC therapies to treat arthritic diseases. Studies on osteoarthritis (OA) have shown positive clinical outcomes, with improved joint function, pain level, and quality of life. In addition, few clinical MSC trials conducted on rheumatoid arthritis (RA) patients have also displayed some optimistic outlook. The largely positive outcomes in clinical trials without severe side effects establish MSCs as promising tools for arthritis treatment. However, further research is required to investigate its applicability in clinical settings. This review discusses the most recent advances in clinical studies on MSC therapies for OA and RA.

scholarly journals Clinical Practice Guidelines for Chagas Disease: Recent Developments and Future Needs

2019 ◽  
Vol 52 ◽  
Author(s):  
Colin Forsyth ◽  
Andrea Marchiol ◽  
Rafael Herazo ◽  
Eric Chatelain ◽  
Carolina Batista ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Chagas Disease ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Future Needs ◽  
Recent Developments

scholarly journals The Evolving Role of Catheter Ablation in Patients With Heart Failure and AF

2019 ◽  
Vol 8 (1) ◽  
pp. 47-53
Author(s):  
Sandeep Prabhu ◽  
Wei H Lim ◽  
Richard J Schilling
Keyword(s):  
Heart Failure ◽  
Clinical Practice ◽  
Catheter Ablation ◽  
Patient Group ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Evidence Base ◽  
Patients With Heart Failure ◽  
Recent Developments

AF and heart failure are emerging epidemics worldwide. Several recent trials have provided a growing evidence base for the benefits of catheter ablation in this patient group, which are yet to be universally adopted in clinical practice guidelines. This paper provides a summary of recent developments in this field and provides pragmatic advice to the treating physician regarding the appropriate role of catheter ablation in the overall management of patients with comorbid AF and heart failure.

Nonviral Vehicles for Gene Delivery

Nano LIFE ◽  
2021 ◽  
Vol 11 (02) ◽  
pp. 2130002
Author(s):  
Eric Warga ◽  
Brian Austin-Carter ◽  
Noelle Comolli ◽  
Jacob Elmer
Keyword(s):  
Gene Delivery ◽  
Lower Cost ◽  
Clinical Applications ◽  
Inorganic Nanoparticles ◽  
Nonviral Gene Delivery ◽  
Viral Gene ◽  
Cationic Polymers ◽  
Recent Developments ◽  
Low Efficiency ◽  
Viral Gene Delivery

Nonviral gene delivery (NVGD) is an appealing alternative to viral gene delivery for clinical applications due to its lower cost and increased safety. A variety of promising nonviral vectors are under development, including cationic polymers, lipids, lipid-polymer hybrids (LPHs) and inorganic nanoparticles. However, some NVGD strategies have disadvantages that have limited their adoption, including high toxicity and low efficiency. This review focuses on the most common NVGD vehicles with an emphasis on recent developments in the field.

Cardiometabolic conditions could be related to vitamin D deficiency. The genetic determinants that affect vitamin D pathways may be solved with nanomedicines.

2021 ◽  
Author(s):  
Moataz Dowaidar
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Clinical Practice ◽  
Vitamin D Deficiency ◽  
Genetic Determinants ◽  
Bulk Materials ◽  
Treatment Regimens ◽  
Recent Developments

Vitamin D deficiency is a risk factor for cardiometabolic disorders.Nanomedicines can be used to treat atherosclerosis and associated ischemicdisorders. They are able to reduce internal clearance pathways and prolongblood circulation. They also have a large surface size and more sensitive andvaried reactivity than bulk materials, making them more effective at targetingand functionalizing nanoparticles for various types of disease. This studyfocuses on the specialized use of nanomedicine for atherosclerotic diseases inpreclinical and clinical practice. It presents the most recent developments innanomedicine-based treatment regimens for the disease. It has the potential tosolve the genetic determinants that influence vitamin D pathways.

Anarchism and Cybernetics: A Missed Opportunity Revisited

2020 ◽  
pp. 35-60
Author(s):  
Thomas Swann
Keyword(s):  
Social Movement ◽  
Viable System Model ◽  
Detailed Understanding ◽  
Functional Roles ◽  
The Core ◽  
Recent Developments ◽  
Functional Hierarchy ◽  
Viable System ◽  
Conceptual Overview ◽  
Missed Opportunity

Chapter Three provides a historical and conceptual overview of both anarchism and cybernetics, focusing on recent developments in anarchist social movement practice and Stafford Beer’s organisational cybernetics respectively. The chapter argues that the core cybernetic principles of complexity, control and autonomy, understood through the overarching idea of self-organisation, can help elaborate a detailed understanding of anarchist organisation. To do so, the chapter develops Beer’s Viable System Model for anarchist social movement organising and uses the example of Occupy to show how the functional hierarchy of Beer’s model can be applied to forms of organisation that are typically understood as rejecting hierarchy. The chapter builds on an important article written by John D. McEwan to show how functional roles in an organisation can be realised on structurally non-hierarchical ways that reinforce the radically democratic and participatory practices of anarchism.

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