P3 and other Long Latency Auditory Evoked Potentials in Presenile Dementia Alzheimer Type and Alcoholic Korsakoff Syndrome

The P300 (P3) and other long latency auditory evoked potentials were measured in 15 patients with presenile dementia Alzheimer type (ATD), 16 patients with alcoholic Korsakoff syndrome (KS) and 23 age-matched control subjects. All were drug free for at least four weeks before testing. The latency of the P3 was significantly longer and the amplitude significantly smaller in the ATD group than in both the KS and control groups. The KS group did not differ significantly from the control group in either latency or amplitude of P3 but both the KS and ATD groups had reduced N1 and P2 compared to controls. Using a combination of P3 latency and amplitude, 70% of the ATD patients could be separated from the other groups with no false positives. These findings suggest that evoked potential recording may be of value in the diagnosis of early ATD.

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Long latency auditory evokedpotentials in malnourished children

CoDAS ◽

10.1590/s2317-1782201300050000 ◽

2013 ◽

Vol 25 (5) ◽

pp. 407-412 ◽

Cited By ~ 7

Author(s):

Renata Parente de Almeida ◽

Carla Gentile Matas

Keyword(s):

Evoked Potentials ◽

Auditory Evoked Potentials ◽

Impedance Measurement ◽

Pure Tone Audiometry ◽

Control Group ◽

Study Group ◽

Malnourished Children ◽

Long Latency ◽

Significant Difference ◽

The Right

PURPOSE: To characterize the findings obtained in the long latency auditory evoked potentials in malnourished children, as well as to compare them to the results obtained for children at the same age who present typical development. METHODS: Sixty-five children aged between 7 and 12 years old, of both genders, were evaluated. The control group consisted of 34 children with normal development and the study group consisted of 31 children diagnosed with malnutrition. All children underwent conventional pure tone audiometry, acoustic impedance measurement, dichotic digit test and long latency auditory evoked potentials. RESULTS: The study group presented a statistically significant difference for latencies of the components P1, N1 and P300. The latencies of these components were higher than those of the control group. Concerning the types of alterations found in the study group, increased latency for P1 and P300 and the absence of response in N1 were predominant. The control group showed a statistically significant difference in the amplitude of P300 when compared to the right and left ears. CONCLUSION: Malnourished children present with changes in the long latency auditory evoked potentials, suggesting a deficit in central auditory pathways and alterations in the processing of acoustic information.

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Characteristic Deviations of Auditory Evoked Potentials in Individuals with Autism Spectrum Disorder

Journal of the American Academy of Audiology ◽

10.1055/s-0041-1730365 ◽

2021 ◽

Vol 32 (06) ◽

pp. 379-385

Author(s):

Kamakshi V. Gopal ◽

Erin C. Schafer ◽

Rajesh Nandy ◽

Ashley Brown ◽

Joshua Caldwell ◽

...

Keyword(s):

Autism Spectrum Disorder ◽

Evoked Potentials ◽

Auditory Evoked Potentials ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Auditory Training ◽

Control Group ◽

Control Groups ◽

And Control ◽

Adults With Asd

Abstract Background Neurological, structural, and behavioral abnormalities are widely reported in individuals with autism spectrum disorder (ASD); yet there are no objective markers to date. We postulated that by using dominant and nondominant ear data, underlying differences in auditory evoked potentials (AEPs) between ASD and control groups can be recognized. Purpose The primary purpose was to identify if significant differences exist in AEPs recorded from dominant and nondominant ear stimulation in (1) children with ASD and their matched controls, (2) adults with ASD and their matched controls, and (3) a combined child and adult ASD group and control group. The secondary purpose was to explore the association between the significant findings of this study with those obtained in our previous study that evaluated the effects of auditory training on AEPs in individuals with ASD. Research Design Factorial analysis of variance with interaction was performed. Study Sample Forty subjects with normal hearing between the ages of 9 and 25 years were included. Eleven children and 9 adults with ASD were age- and gender-matched with neurotypical peers. Data Collection and Analysis Auditory brainstem responses (ABRs) and auditory late responses (ALRs) were recorded. Adult and child ASD subjects were compared with non-ASD adult and child control subjects, respectively. The combined child and adult ASD group was compared with the combined child and adult control group. Results No significant differences in ABR latency or amplitude were observed between ASD and control groups. ALR N1 amplitude in the dominant ear was significantly smaller for the ASD adult group compared with their control group. Combined child and adult data showed significantly smaller amplitude for ALR N1 and longer ALR P2 latency in the dominant ear for the ASD group compared with the control group. In our earlier study, the top predictor of behavioral improvement following auditory training was ALR N1 amplitude in the dominant ear. Correspondingly, the ALR N1 amplitude in the dominant ear yielded group differences in the current study. Conclusions ALR peak N1 amplitude is proposed as the most feasible AEP marker in the evaluation of ASD.

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Long Latency Auditory Evoked Potentials and Object-Related Negativity Based on Harmonicity in Hearing-Impaired Children

Neuroscience Research ◽

10.1016/j.neures.2022.01.001 ◽

2022 ◽

Author(s):

Saeideh Mehrkian ◽

Abdollah Moossavi ◽

Nasrin Gohari ◽

Mohammad Ali Nazari ◽

Enayatollah Bakhshi ◽

...

Keyword(s):

Evoked Potentials ◽

Auditory Evoked Potentials ◽

Hearing Impaired ◽

Long Latency ◽

Impaired Children ◽

Hearing Impaired Children

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Auditory Responses

MEG-EEG Primer ◽

10.1093/med/9780190497774.003.0012 ◽

2017 ◽

pp. 200-213

Author(s):

Riitta Hari ◽

Aina Puce

Keyword(s):

Steady State ◽

Evoked Potentials ◽

Auditory Evoked Potentials ◽

Evoked Responses ◽

Brainstem Auditory Evoked Potentials ◽

Auditory Evoked Responses ◽

Auditory Responses ◽

Long Latency ◽

Left And Right ◽

Auditory Cortices

This chapter briefly describes the various types of evoked and event-related responses that can be recorded in response to auditory stimulation, such as clicks and tones, and speech. Transient auditory-evoked responses are generally grouped into three major categories according to their latencies: (a) brainstem auditory evoked potentials occur within the first 10 ms, typically with 5–7 deflections, (b) middle-latency auditory-evoked potentials occur within 12 to 50 ms, and (c) long-latency auditory-evoked potentials range from about 50 to 250 ms with generators in the supratemporal auditory cortex. Steady-state auditory responses can be elicited by periodic stimuli, They can be used in frequency-tagging experiments, for example in following inputs from the left and right ear to the auditory cortices of both hemispheres.

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