Pre-morbid Psychopathology in Schizophrenia Spectrum

1989 ◽  
Vol 155 (05) ◽  
pp. 623-627 ◽  
Author(s):  
Josef Parnas ◽  
Aage Jørgensen
Keyword(s):  
Longitudinal Study ◽  
High Risk ◽  
Prospective Longitudinal Study ◽  
Schizophrenia Spectrum ◽  
Prospective Longitudinal

In a prospective, longitudinal study of high-risk offspring of schizophrenic mothers, of several dimensions of pre-morbid behaviour ‘peculiarity’ predicted subsequent schizophrenia or schizotypy. Peculiarity/eccentricity may represent a subtle marker of the schizophrenic genotype. ‘Pre-schizophrenics', as compared with ‘pre-schizotypes', were characterised by affective dyscontrol, reflected in less introverted and more disturbed behaviour.

Pre-morbid Psychopathology in Schizophrenia Spectrum

1989 ◽  
Vol 155 (5) ◽  
pp. 623-627 ◽  
Author(s):  
Josef Parnas ◽  
Aage Jørgensen
Keyword(s):  
Longitudinal Study ◽  
High Risk ◽  
Prospective Longitudinal Study ◽  
Schizophrenia Spectrum ◽  
Prospective Longitudinal

In a prospective, longitudinal study of high-risk offspring of schizophrenic mothers, of several dimensions of pre-morbid behaviour ‘peculiarity’ predicted subsequent schizophrenia or schizotypy. Peculiarity/eccentricity may represent a subtle marker of the schizophrenic genotype. ‘Pre-schizophrenics', as compared with ‘pre-schizotypes', were characterised by affective dyscontrol, reflected in less introverted and more disturbed behaviour.

Peripartum outcomes of high-risk pregnancies complicated by oligo- and polyhydramnios: A prospective longitudinal study

2010 ◽  
Vol 36 (2) ◽  
pp. 268-277 ◽  
Author(s):  
Everett F. Magann ◽  
Dorota A. Doherty ◽  
Monica A. Lutgendorf ◽  
Marcia I. Magann ◽  
Suneet P. Chauhan ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
High Risk ◽  
Prospective Longitudinal Study ◽  
Prospective Longitudinal

Development and the fragmented self: Longitudinal study of dissociative symptomatology in a nonclinical sample

1997 ◽  
Vol 9 (4) ◽  
pp. 855-879 ◽  
Author(s):  
JOHN R. OGAWA ◽  
L. ALAN SROUFE ◽  
NANCY S. WEINFIELD ◽  
ELIZABETH A. CARLSON ◽  
BYRON EGELAND
Keyword(s):  
Longitudinal Study ◽  
High Risk ◽  
Developmental Psychopathology ◽  
Age Of Onset ◽  
Sense Of Self ◽  
Strong Support ◽  
Prospective Longitudinal Study ◽  
Extreme Deviation ◽  
Highly Correlated ◽  
Prospective Longitudinal

Dissociative behaviors and their relation to both the self and self-organization were examined using the developmental psychopathology perspective in a prospective longitudinal study of high-risk children. Participants were 168 young adults (n = 79 females, n = 89 males, age = 18–19 years) considered high-risk for poor developmental outcomes at birth due to poverty. The present study investigated whether trauma, sense of self, quality of early mother–child relationship, temperament, and intelligence were related to dissociative symptomatology measured at four times across 19 years. Findings were (a) age of onset, chronicity and severity of trauma were highly correlated and predicted level of dissociation; (b) both the avoidant and disorganized patterns of attachment were strong predictors of dissociation; (c) dissociation in childhood may be a more normative response to disruption and stress, while dissociation in adolescence and young adulthood may be more indicative of psychopathology; (d) preliminary support was found for a model proposed by G. Liotti that links disorganized attachment, later trauma, and dissociation in adulthood; and (e) strong support was found for N. Waller, F. W. Putnam, and E. B. Carlson's contention that psychopathological dissociation should not be viewed as the top end of a continuum of dissociative symptomatology, but as a separate taxon that represents an extreme deviation from normal development.

scholarly journals Rationale, study design and methodology of the hypertension registry: a Pan-India, prospective, longitudinal study to assess management and real-world outcomes of high-risk essential hypertension

2021 ◽  
Vol 8 (3) ◽  
pp. 223
Author(s):  
Jabir Abdullakutty ◽  
Jay Shah ◽  
Abraham Oomman ◽  
J. Ezhilan ◽  
N. C. Krishnamani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Longitudinal Study ◽  
High Risk ◽  
Clinical Outcomes ◽  
Real World ◽  
Trial Registration ◽  
Dose Titration ◽  
Treatment Preferences ◽  
Prospective Longitudinal Study ◽  
Prospective Longitudinal

<p class="abstract"><strong>Background:</strong> India contributes significantly towards a large part of the worldwide epidemic of hypertension (HTN) and its associated complications. As, there are limited longitudinal studies available in India to understand its occurrence over time, this Pan-India longitudinal study will aid to assess the real world outcomes of HTN across the country.</p><p class="abstract"><strong>Methods:</strong> This was a prospective, multi-centered, longitudinal, observational study investigating a large COHORT of people with HTN across India over a period of one year. The primary objective of this study was to evaluate blood pressure (BP) control and clinical outcomes in high-risk hypertensive patients distributed over 5 visits (including baseline visit). The secondary objective is to assess the co-morbidities/risk factors in different clinical settings across India. Participants (4,000) with HTN will be included from 200 centres across India and data will be recorded for the use of anti-hypertensives, demographics, socio-economic status, anthropometric measurements, family history, personal history, risk factors, co-morbid conditions and physician treatment preferences. Overall, clinical practice patterns were assessed for their relationship with clinical outcomes.</p><p class="abstract"><strong>Conclusions: </strong>This study is expected to reveal the trends in complications associated with HTN, treatment strategies used by physicians, and correlation among treatment, control and complications of HTN within the Indian context. The outcome of this study will help to identify the burden of HTN, along with pin-pointing the emergence of early-onset complications and dose titration patterns. This will eventually help to develop person-centred care and facilitate public health agencies to invest appropriate resources in the management of high-risk HTN across India.</p><p class="abstract"><strong>Trial registration:</strong> Since this is a real world evidence study no trial registration was needed as per Indian regulations.</p>

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