Depression and self-reported memory problems in adult-onset cancer survivors.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 9586-9586
Author(s):  
Pascal Jean-Pierre ◽  
Paul Winters

9586 Background: Memory impairments are debilitating adverse effects of cancer and its treatments. Depression may predispose or exacerbate memory problems. We examined the relationship between depression and memory problems in adult-onset cancer survivors. Methods: We included data from individuals who completed the National Health and Nutrition Examination Survey, a nationally representative, stratified, multistage probability sample of the civilian, non-institutionalized population of the United States from 2005 to 2010. We excluded individuals with a history of brain cancer or stroke since these conditions are expected to cause cognitive problems because of direct brain insults. We determined the prevalence of depression and its relationship to memory problems in cancer survivors by weighting our results proportionally. We controlled for demographic predictors of memory problems. Results: The sample included 14249 adults (6875 men and 7274 women) age 20 years and older. There were 6959 Whites, 2792 Blacks, 3903 Hispanics, and 589 other race/multiracial. Overall, individuals in the United States with a history of depression were 8.4 times more likely to report memory problems (Odds Ratio (OR), 8.406; 95%CI, 6.73 to 10.64). We further explored the depression-memory relationship in a subsample of cancer survivors. Adjusting for age, sex, race-ethnicity, education, income, and general health, cancer survivors with a history of depression were approximately 5 times more likely to report memory problems (N=1283; OR, 4.921; 95%CI, 2.141 to 11.313) than those without a history of depression. Other predictors of memory problems were age (≥ 60 years old, OR = 4.756, 95%CI, 1.957 to 11.560) and lower income (OR, 3.721; 95%CI, 1.951 to 7.098). Conclusions: The likelihood of memory problems is higher in cancer survivors with a history of depression. Future studies are needed to systematically delineate the depression-memory problems relationship, and to inform the development of interventions to treat these conditions for cancer survivors.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 9588-9588
Author(s):  
Pascal Jean-Pierre ◽  
Michael Grandner ◽  
Ashley Jean-Pierre ◽  
Sheila N. Garland ◽  
Gloria Maciorowski ◽  
...  

2018 ◽  
Vol 27 (8) ◽  
pp. 2039-2044 ◽  
Author(s):  
Gemechu B. Gerbi ◽  
Stranjae Ivory ◽  
Elaine Archie-Booker ◽  
Mechelle D. Claridy ◽  
Stephanie Miles-Richardson

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. e20588-e20588
Author(s):  
Pascal Jean-Pierre ◽  
Michael Grandner ◽  
Ashley Jean-Pierre ◽  
Sheila N. Garland ◽  
Erin Richards ◽  
...  

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e18085-e18085
Author(s):  
Maryam Doroudi ◽  
Diarmuid Coughlan ◽  
Matthew P. Banegas ◽  
K Robin Yabroff

e18085 Background: Financial hardships experienced by cancer survivors in the United States have become significant social and public health issues. Few studies have assessed the underlying financial holdings, including ownership and values of assets and debts, of individuals following a cancer diagnosis. This study assessed the association between a cancer history and asset ownership, debt, and net worth. Methods: We identified 1,603 cancer survivors and 34,915 individuals without a history of cancer aged 18-64 from the nationally representative Medical Expenditure Panel Survey (MEPS) Household Component and Asset sections (years 2008-2011). Descriptive statistics were used to assess demographic characteristics, cancer history, asset ownership, debt, and net worth by cancer history. Regression analysis was conducted to assess the association between cancer history and net worth, stratified by age group (18-34, 35-44, 45-54, and 55-64 years) to reflect stages of the life-course. Results: Asset ownership was least common for cancer survivors and individuals without a cancer history in the 18-34 age group and most common in the 55-64 age group. Cancers survivors aged 45-54 had a lower proportion of home ownership than individuals without a cancer history (59% vs 67%; p = 0.001). Nearly 20% of all respondents reported at least some debt. The proportion of cancer survivors with debt was higher than individuals without a history of cancer, especially in the 18-34 age group (41% vs 27%; p < 0.001), although it did not vary by age group. When asset and debt values were combined to assess net worth, cancer survivors aged 45-54 were significantly more likely to have a negative net worth and significantly less likely to have a positive net worth than those individuals without a history of cancer in fully adjusted models. Findings on net worth were similar in the 18-34 age group, although only statistically significant in unadjusted and partially adjusted models. Conclusions: We found that cancer history is associated with asset ownership, debt, and net worth, especially in those aged 45-54 years. Longitudinal studies to assess patterns of financial holdings throughout the cancer experience are warranted.


2017 ◽  
Vol 35 (1) ◽  
pp. 78-85 ◽  
Author(s):  
Nikki A. Hawkins ◽  
Ashwini Soman ◽  
Natasha Buchanan Lunsford ◽  
Steven Leadbetter ◽  
Juan L. Rodriguez

Purpose This study used population-based data to estimate the percentage of cancer survivors in the United States reporting current medication use for anxiety and depression and to characterize the survivors taking this type of medication. Rates of medication use in cancer survivors were compared with rates in the general population. Methods We analyzed data from the National Health Interview Survey, years 2010 to 2013, identifying cancer survivors (n = 3,184) and adults with no history of cancer (n = 44,997) who completed both the Sample Adult Core Questionnaire and the Adult Functioning and Disability Supplement. Results Compared with adults with no history of cancer, cancer survivors were significantly more likely to report taking medication for anxiety (16.8% v 8.6%, P < .001), depression (14.1% v 7.8%, P < .001), and one or both of these conditions combined (19.1% v 10.4%, P < .001), indicating that an estimated 2.5 million cancer survivors were taking medication for anxiety or depression in the United States at that time. Survivor characteristics associated with higher rates of medication use for anxiety included being younger than 65 years old, female, and non-Hispanic white, and having public insurance, a usual source of medical care, and multiple chronic health conditions. Survivor characteristics associated with medication use for depression were largely consistent with those for anxiety, with the exceptions that insurance status was not significant, whereas being widowed/divorced/separated was associated with more use. Conclusion Cancer survivors in the United States reported medication use for anxiety and depression at rates nearly two times those reported by the general public, likely a reflection of greater emotional and physical burdens from cancer or its treatment.


Cancer ◽  
2021 ◽  
Author(s):  
Elizabeth K. Do ◽  
Albert J. Ksinan ◽  
Sunny Jung Kim ◽  
Egidio G. Del Fabbro ◽  
Bernard F. Fuemmeler

Cancer ◽  
2017 ◽  
Vol 123 (8) ◽  
pp. 1453-1463 ◽  
Author(s):  
Zhiyuan Zheng ◽  
Xuesong Han ◽  
Gery P. Guy ◽  
Amy J. Davidoff ◽  
Chunyu Li ◽  
...  

2021 ◽  
Author(s):  
Kennethea A. Wilson ◽  
Sarahmona M. Przybyla ◽  
Jacob Bleasdale ◽  
Steven Gabriel ◽  
Natalie Leblanc ◽  
...  

Abstract In the United States, low rates of pre-exposure prophylaxis (PrEP) awareness and utilization persist among Black adults. To date, few studies have assessed PrEP awareness and use among a nationally representative sample of Black adults. The present study explored factors associated with PrEP awareness and use among Black adults in the United States. Most participants were unaware of PrEP (71%). Those reporting a history of incarceration [aOR 1.73 (1.04, 2.90), p <.05] and lifetime sexually transmitted infection testing [aOR 1.76 (1.19, 2.59), p <.05] had greater odds of awareness. In the sample, only 6% of participants had ever taken PrEP. Those with a history of incarceration [aOR 9.96 (2.82, 35.14), p <.05], concurrent sexual partners [aOR 1.09 (1.00, 1.18), p <.05], and substance use during sex [aOR 4.23 (1.02, 17.48), p <.05] had greater odds of use. Interventions to improve PrEP uptake among Black adults must consider the contextual factors associated with awareness and use.


Stroke ◽  
2021 ◽  
Author(s):  
Neal S. Parikh ◽  
Melvin Parasram ◽  
Halina White ◽  
Alexander E. Merkler ◽  
Babak B. Navi ◽  
...  

Background and Purpose: Continued smoking after stroke is associated with a high risk of stroke recurrence and other cardiovascular disease. We sought to comprehensively understand the epidemiology of smoking cessation in stroke survivors in the United States. Furthermore, we compared smoking cessation in stroke and cancer survivors because cancer is another smoking-related condition in which smoking cessation is prioritized. Methods: We performed a cross-sectional analysis of data from the Centers for Disease Control and Prevention Behavioral Risk Factor Surveillance System, an annual, nationally representative health survey. Using pooled data from 2013 to 2019, we identified stroke and cancer survivors with a history of smoking. We used survey procedures to estimate frequencies and summarize quit ratios with attention to demographic and geographic (state-wise and rural-urban) factors for stroke survivors. The quit ratio is conventionally defined as the proportion of ever smokers who have quit. Then, we used multivariable logistic regression to compare quit ratios in stroke and cancer survivors while adjusting for demographics and smoking-related comorbidities. Results: Among 4 434 604 Americans with a history of stroke and smoking, the median age was 68 years (interquartile range, 59–76), and 45.4% were women. The overall quit ratio was 60.8% (95% CI, 60.1%–61.6%). Quit ratios varied by age group, sex, race and ethnicity, and several geographic factors. There was marked geographic variation in quit ratios, ranging from 48.3% in Kentucky to 71.5% in California. Furthermore, compared with cancer survivors, stroke survivors were less likely to have quit smoking (odds ratio, 0.72 [95% CI, 0.67–0.79]) after accounting for differences in demographics and smoking-related comorbidities. Conclusions: There were considerable demographic and geographic disparities in smoking quit ratios in stroke survivors, who were less likely to have quit smoking than cancer survivors. A targeted initiative is needed to improve smoking cessation for stroke survivors.


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