Impact of protein supplementation on lean muscle mass in adult survivors of childhood cancer engaged in resistance training.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 10027-10027
Author(s):  
Matthew R Krull ◽  
Carrie R. Howell ◽  
Robyn Partin, MS ◽  
Ginger Carney ◽  
Daniel A. Mulrooney ◽  
...  
Keyword(s):  
Resistance Training ◽  
Muscle Strength ◽  
Childhood Cancer ◽  
Training Program ◽  
Muscle Mass ◽  
Adult Survivors ◽  
Protein Supplementation ◽  
Resistance Training Program ◽  
Lean Muscle Mass ◽  
Survivors Of Childhood Cancer

10027 Background: Muscle weakness, low lean muscle mass and poor physical performance are prevalent among adult survivors of childhood cancer. We evaluated the effects of resistance training with and without protein supplementation on lean muscle mass, and muscle strength among childhood cancer survivors. Methods: This double-blind placebo-controlled trial enrolled survivors aged ≥18 to < 45 years. Participants were randomized to resistance training with daily protein supplement (21g protein/day, 90kcal) (RT+S) or resistance training with placebo (sucrose, 90kcal) (RT+P). Both groups received educational materials, access to a local fitness center and a tailored resistance training program with tapered supervision. Lean muscle mass and muscle strength were assessed at baseline and 24 weeks, using dual x-ray absorptiometry and dynamometer testing respectively. Mean changes were compared within and between groups. Results: Of 93 participants randomized, 57 completed the 24-week intervention (24 in RT+S, 33 in RT+P). The mean age was 33.1 (SD 7.0), 67% were white and 47% female. The RT+S group had a significant increase in lean body mass (1.05 kg [SD 2.34], p = 0.04), while the RT+P group did not (0.13 kg [SD 2.19], p = 0.74). Mean change in handgrip strength also improved in the RT+S group (1.98 [SD 4.30], p = 0.03); change approached significance in the RT+P group (1.49 [SD 4.60], p = 0.07). All survivors significantly improved their strength over time (Table) as measured by one max repetition test at baseline and follow-up. Conclusions: Preliminary findings indicate that a supervised resistance training program among adult survivors of childhood cancer that includes protein supplementation is feasible and may increase total lean body mass and muscle strength. Clinical trial information: NCT02501460. [Table: see text]

Free leucine supplementation during an 8-week resistance training program does not increase muscle mass and strength in untrained young adult subjects

Amino Acids ◽  
2017 ◽  
Vol 49 (7) ◽  
pp. 1255-1262 ◽  
Author(s):  
Andreo Fernando Aguiar ◽  
Alan Pablo Grala ◽  
Rubens Alexandre da Silva ◽  
Lúcio Flávio Soares-Caldeira ◽  
Francis Lopes Pacagnelli ◽  
...  
Keyword(s):  
Young Adult ◽  
Resistance Training ◽  
Training Program ◽  
Muscle Mass ◽  
Leucine Supplementation ◽  
Resistance Training Program ◽  
Increase Muscle Mass

The effect of a resistance-training program on muscle strength, physical workload, muscle fatigue and musculoskeletal discomfort: An experiment

2009 ◽  
Vol 40 (3) ◽  
pp. 396-403 ◽  
Author(s):  
Heleen H. Hamberg-van Reenen ◽  
Bart Visser ◽  
Allard J. van der Beek ◽  
Birgitte M. Blatter ◽  
Jaap H. van Dieën ◽  
...  
Keyword(s):  
Resistance Training ◽  
Muscle Strength ◽  
Training Program ◽  
Muscle Fatigue ◽  
Physical Workload ◽  
Musculoskeletal Discomfort ◽  
Resistance Training Program

scholarly journals Home-Based Resistance Training for Older Subjects during the COVID-19 Outbreak in Italy: Preliminary Results of a Six-Months RCT

2020 ◽  
Vol 17 (24) ◽  
pp. 9533
Author(s):  
Jacopo Antonino Vitale ◽  
Matteo Bonato ◽  
Stefano Borghi ◽  
Carmelo Messina ◽  
Domenico Albano ◽  
...  
Keyword(s):  
Resistance Training ◽  
Muscle Strength ◽  
Training Program ◽  
T Test ◽  
Controlled Study ◽  
Group Differences ◽  
Control Group ◽  
Resistance Training Program ◽  
Home Based ◽  
Older Subjects

Background. The aim of this study was to evaluate the effect of a six-month home-based resistance-training program on muscle health and physical performance in healthy older subjects during the unique condition of home confinement caused by the COVID-19 pandemic. Methods. This was a randomized-controlled study that enrolled older participants that were allocated to either an experimental group performing the six-months exercise prescription (EXE) or a control group (CON). At the beginning (PRE), and after 6 months (POST), participants were assessed for muscle strength, balance, gait assessment and body composition by dual energy X-ray absorptiometry and magnetic resonance imaging. Normality distribution of data was checked with the D’Agostino and Pearson test and changes between PRE and POST were assessed by paired Student’s t-test while percentage and absolute changes between groups at POST were tested by unpaired t-test. Results. Nine participants were included for the final analysis: EXE, n = 5 (age: 66 ± 4; BMI: 27.5 ± 3.7) and CON, n = 4 (age: 71 ± 9; BMI: 24.2 ± 4.1). Significant PRE-to-POST changes were observed in the EXE group only in the chair-stand test (+19.8%, p = 0.048 and ES:1.0, moderate) and in total fat mass (+5.0%, p = 0.035 and ES:1.4, large) with no between-group differences. Moreover, EXE had significantly higher absolute thigh CSA values than CON at POST (14.138 ± 2977 vs. 9039 ± 1015, p = 0.0178, ES = 1.7). No other within- and between-group differences were detected. Conclusions. The home-based resistance-training program during the lockdown period, caused by the COVID-19 outbreak, determined only within-group improvement in lower limb muscle strength but not in muscle mass and composition in older subjects. Home confinement may partially explain the increase in total body fat due to a reduced daily PA regime and altered diet pattern.

scholarly journals The effects of a 12-week resistance training program on muscle strength of elderly women

2002 ◽  
Vol 16 (2) ◽  
pp. 220 ◽  
Author(s):  
Ericka Sant’Ana Federici Trancoso ◽  
Paulo de Tarso Veras Farinatti
Keyword(s):  
Resistance Training ◽  
Muscle Strength ◽  
Training Program ◽  
Elderly Women ◽  
Resistance Training Program ◽  
Leg Press

O treinamento da força (TF) tem se revelado eficaz em idosos frágeis. Contudo, dúvidas persistem sobre a resposta ao treinamento em idosos com nível de independência funcional elevado. O objetivo do estudo foi observar os efeitos de 12 semanas de TF sobre a força muscular em mulheres idosas funcionalmente autônomas, mas sem experiência prévia com este tipo de treinamento. Trinta e cinco mulheres com 62 a 77 anos de idade passaram por anamnese e teste de esforço com ECG. Uma voluntária foi excluída por utilizar marcapasso, outras duas exibiram sinais de isquemia, seis não compareceram ao teste de esforço e sete abandonaram o TF por razões .diversas. A casuística contou com 19 indivíduos (idade = 69 ± 5 anos). Foram realizadas, duas vezes por semana durante 12 semanas, duas séries de 10 repetições máximas (RM) em exercícios para membros inferiores (“leg-press”) e superiores (supino reto). As médias semanais do volume de treinamento foram comparadas através de ANOVA para medidas repetidas (p < 0,05). Os resultados indicaram tendência à melhoria da força durante o período observado, nos dois exercícios, da ordem de 58% para o “leg-press” e 61% para o supino. O ganho de força evoluiu rapidamente nas primeiras quatro semanas, tendendo a estabilizar-se nas semanas finais. Conclui-se que o TF pode apresentar resultados positivos em idosas com bom nível de independência funcional. A possibilidade destes ganhos ocorrerem em treinamentos de prazo mais longo, todavia, revela-se duvidosa

scholarly journals Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2337 ◽  
Author(s):  
Maria Amasene ◽  
Ariadna Besga ◽  
Iñaki Echeverria ◽  
Miriam Urquiza ◽  
Jonatan R. Ruiz ◽  
...  
Keyword(s):  
Resistance Training ◽  
Physical Function ◽  
Whey Protein ◽  
Muscle Mass ◽  
Elderly Population ◽  
Mini Nutritional Assessment ◽  
Protein Supplementation ◽  
Protein Supplement ◽  
Resistance Training Program ◽  
Hospitalized Elderly

Age-related strength and muscle mass loss is further increased after acute periods of inactivity. To avoid this, resistance training has been proposed as an effective countermeasure, but the additional effect of a protein supplement is not so clear. The aim of this study was to examine the effect of a whey protein supplement enriched with leucine after resistance training on muscle mass and strength gains in a post-hospitalized elderly population. A total of 28 participants were included and allocated to either protein supplementation or placebo supplementation following resistance training for 12 weeks (2 days/week). Physical function (lower and upper body strength, aerobic capacity and the Short Physical Performance Battery (SPPB) test), mini nutritional assessment (MNA) and body composition (Dual X-ray Absorptiometry) were assessed at baseline and after 12 weeks of resistance training. Both groups showed improvements in physical function after the intervention (p < 0.01), but there were no further effects for the protein group (p > 0.05). Muscle mass did not improve after resistance training in either group (p > 0.05). In conclusion, 12 weeks of resistance training are enough to improve physical function in a post-hospitalized elderly population with no further benefits for the protein-supplemented group.

scholarly journals Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial

2015 ◽  
Vol 114 (8) ◽  
pp. 1237-1245 ◽  
Author(s):  
Denise Zdzieblik ◽  
Steffen Oesser ◽  
Manfred W. Baumstark ◽  
Albert Gollhofer ◽  
Daniel König
Keyword(s):  
Body Composition ◽  
Resistance Training ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Training Programme ◽  
Protein Supplementation ◽  
Controlled Study ◽  
Elderly Subjects ◽  
Collagen Peptides ◽  
Collagen Peptide

AbstractProtein supplementation in combination with resistance training may increase muscle mass and muscle strength in elderly subjects. The objective of this study was to assess the influence of post-exercise protein supplementation with collagen peptidesv.placebo on muscle mass and muscle function following resistance training in elderly subjects with sarcopenia. A total of fifty-three male subjects (72·2 (sd4·68) years) with sarcopenia (class I or II) completed this randomised double-blind placebo-controlled study. All the participants underwent a 12-week guided resistance training programme (three sessions per week) and were supplemented with either collagen peptides (treatment group (TG)) (15 g/d) or silica as placebo (placebo group (PG)). Fat-free mass (FFM), fat mass (FM) and bone mass (BM) were measured before and after the intervention using dual-energy X-ray absorptiometry. Isokinetic quadriceps strength (IQS) of the right leg was determined and sensory motor control (SMC) was investigated by a standardised one-leg stabilisation test. Following the training programme, all the subjects showed significantly higher (P<0·01) levels for FFM, BM, IQS and SMC with significantly lower (P<0·01) levels for FM. The effect was significantly more pronounced in subjects receiving collagen peptides: FFM (TG +4·2 (sd2·31) kg/PG +2·9 (sd1·84) kg;P<0·05); IQS (TG +16·5 (sd12·9) Nm/PG +7·3 (sd13·2) Nm;P<0·05); and FM (TG –5·4 (sd3·17) kg/PG –3·5 (sd2·16) kg;P<0·05). Our data demonstrate that compared with placebo, collagen peptide supplementation in combination with resistance training further improved body composition by increasing FFM, muscle strength and the loss in FM.

scholarly journals A Review on Aging, Sarcopenia, Falls, and Resistance Training in Community-Dwelling Older Adults

2022 ◽  
Vol 19 (2) ◽  
pp. 874
Author(s):  
Filipe Rodrigues ◽  
Christophe Domingos ◽  
Diogo Monteiro ◽  
Pedro Morouço
Keyword(s):  
Resistance Training ◽  
Muscle Strength ◽  
Physical Exercise ◽  
Muscle Mass ◽  
Well Being ◽  
The Elderly ◽  
Community Dwelling ◽  
Narrative Review ◽  
Current Evidence ◽  
Resistance Training Program

As aging continues to grow in our society, sarcopenia and associated fall risk is considered a public health problem since falling is the third cause of chronic disability. Falls are negatively related to functionality and independence and positively associated with morbidity and mortality. The cost of treatment of secondary injuries related to falls is high. For example, one in ten fall incidents leads to bone fractures and several other comorbidities. As demonstrated by several experimental studies, adopting a more active lifestyle is critical for reducing the number of fall episodes and their consequences. Therefore, it is essential to debate the proven physical exercise methods to reduce falls and fall-related effects. Since muscle mass, muscle strength, bone density, and cartilage function may play significant roles in daily activities, resistance training may positively and significantly affect the elderly. This narrative review aimed to examine current evidence on existing resistance training using resistance machines and bodyweight or low-cost equipment for the elderly and how they are related to falls and fall-related consequences. We provide theoretical links between aging, sarcopenia, and falls linking to resistance training and offer practical suggestions to exercise professionals seeking to promote regular physical exercise to promote quality of life in this population. Exercise programs focusing on strength may significantly influence muscle mass and muscle strength, minimizing functional decline and risk of falling. Resistance training programs should be customized to each elderly according to age, sex, and other fundamental and individual aspects. This narrative review provides evidence to support recommendations for practical resistance training in the elderly related to intensity and volume. A properly designed resistance training program with adequate instructions and technique is safe for the elderly. It should include an individualized approach based on existing equipment (i.e., body weight, resistance machines). Existing literature shows that exercise performance towards 2–3 sets of 1–2 exercises per major muscle group, performing 5–8 repetitions or achieving intensities of 50–80% of 1RM, 2–3 times per week should be recommended, followed by training principles such as periodization and progression. Bearing this in mind, health and exercise professionals should combine efforts focusing on efficient strategies to reduce falls among the elderly and promote higher experiences of well-being at advanced stages in life.

scholarly journals Resistance Training Improves Muscle Strength and Function, Regardless of Protein Supplementation, in the Mid- to Long-Term Period after Gastric Bypass

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 14
Author(s):  
Gabriela S. Oliveira ◽  
Flávio T. Vieira ◽  
Fernando Lamarca ◽  
Ricardo M. Lima ◽  
Kênia M. B. Carvalho ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Resistance Training ◽  
Muscle Strength ◽  
Whey Protein ◽  
Controlled Trial ◽  
Peak Torque ◽  
Protein Supplementation ◽  
Placebo Control ◽  
Resistance Training Program

Inadequate protein intake and low levels of physical activity are common long-term sequelae after bariatric surgery and can negatively affect muscle strength (MS) and physical function (PF). The study investigated the effects of resistance training with or without protein supplementation on MS and PF. The study, which involved a 12-week controlled trial (n = 61) of individuals 2–7 years post-Roux-en-Y gastric bypass (RYGB), comprised four groups: whey protein supplementation (PRO; n = 18), maltodextrin placebo (control [CON]; n = 17), resistance training combined with placebo (RTP; n = 11), and resistance training combined with whey protein supplementation (RTP+PRO; n = 15). An isokinetic dynamometer was used to measure MS (peak torque at 60°/s and 180°/s). PF was measured with the 30-s sit-to-stand (30-STS), 6-min walk (6-MWT), and timed up-and-go (TUG) tests. There were improvements in the absolute and relative-to-bodyweight peak torque at 60°/s and 180°/s, TUG, 6-MWT and 30-STS in the RTP and RTP+PRO groups, but not in the CON and PRO groups. Changes in MS were significantly correlated with changes in PF between the pre- and post-intervention periods. A supervised resistance training program, regardless of protein supplementation, improved MS and PF in the mid-to-long-term period after RYGB and can lead to clinical benefits and improved quality of life.

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