Long-term and late effects (LLEs), anxiety, and depression among long-term survivors of pediatric, adolescent, and young adult (P-AYA) cancer.

2019 ◽  
Vol 37 (31_suppl) ◽  
pp. 143-143
Author(s):  
Linda A. Jacobs ◽  
Abigail N. Blauch ◽  
Donna A. Pucci ◽  
Steven C Palmer
Keyword(s):  
Body Image ◽  
Low Income ◽  
Depression Scale ◽  
Psychosocial Outcomes ◽  
Well Being ◽  
Anxiety And Depression ◽  
Psychological Well Being ◽  
Income Status ◽  
Body Image Concerns

143 Background: Adult P-AYA cancer survivors report numerous LLEs, as well as potential decrements in psychological well-being. The relationship between LLEs and psychological well-being, however, has not been well described in this population. We examined this relationship and predictors of LLEs and well-being in a sample of adult survivors of P-AYA cancer. Methods: Survivors of P-AYA cancer > 2 years from end of treatment completed the Hospital Anxiety and Depression Scale (HADS) and a measure of presence and severity of 11 common LLEs following a survivorship visit. LLEs included fatigue, pain, insomnia, numbness, joint or muscle pain, difficulties with concentration or memory, body image concerns, decreased sexual interest, and weight. Results: Participants (N = 237) were predominately white (89%), college educated (76%), single (63%), and had an annual income of > $60,000 (69%). A plurality had diagnoses of leukemia (30%) or Hodgkin's lymphoma (29%) treated 17 years previously. Treatment included surgery (35%), chemotherapy (91%), XRT (59%), and BMT (17%). Anxiety (M = 6.02; SD = 3.07) and depression (M = 2.54; SD = 2.85) scores were generally low and below the cutpoint of 8 (all t < -7.8; all p < .001 ), although 21% and 9% screened positively for anxiety or depression, respectively. 91% of participants reported at least 1 LLE (M = 4.8, SD = 3.1), most commonly fatigue (73%), concentration (57%) and memory difficulties (53%), and body image problems (48%). Total number LLEs was associated with elevations in both anxiety and depression, as was severity for each individual LLE (all p < 0.001). Only one LLE, difficulty with body image, produced large effects for both anxiety and depression. Low income status were associated with both LLEs and elevations in anxiety and depression (all p < 0.01). Conclusions: Most P-AYA survivors report LLEs. Although anxiety and depression are modest, elevations occur in a substantial number of survivors. Presence of LLEs is associated with worse psychosocial outcomes, particularly difficulties with body image. Lower income individuals and those with body image concerns may be at particular risk of poorer psychosocial outcomes.

scholarly journals The long-term caregiver burden in WHO grade I and II meningioma: it’s not just the patient

2020 ◽  
Author(s):  
Amir H Zamanipoor Najafabadi ◽  
Pim B van der Meer ◽  
Florien W Boele ◽  
Martin J B Taphoorn ◽  
Martin Klein ◽  
...  
Keyword(s):  
Caregiver Burden ◽  
Informal Caregivers ◽  
Depression Scale ◽  
Well Being ◽  
Anxiety And Depression ◽  
Cross Sectional ◽  
Who Grade ◽  
Hrqol Questionnaire ◽  
Sf 36

Abstract Background Little is known about long-term caregiver burden in meningioma patients. We assessed meningioma caregiver burden, its association with informal caregiver’s well-being and possible determinants. Methods In this multicenter cross-sectional study, informal caregivers completed the Caregiver Burden Scale (five domains and total score). Patients completed a disease-specific health-related quality of life (HRQoL) questionnaire focusing on symptoms (EORTC QLQ-BN20) and underwent neurocognitive assessment. Both groups completed a generic HRQoL questionnaire (SF-36) and the Hospital Anxiety and Depression Scale. We assessed the association between caregiver burden and their HRQoL, anxiety and depression. Furthermore, we assessed determinants for the caregiver burden. Multivariable regression analysis was used to correct for confounders. Results 129 informal caregivers were included (median 10 years after patients’ treatment). Caregivers reported burden in ≥1 domain (35%) or total burden score (15%). A one-point increase in total caregiver burden score was associated with a clinically relevant decrease in caregiver’s HRQoL (SF-36) in 5/8 domains (score range: -10.4 to -14.7) and 2/2 component scores (-3.5 to -5.9), and with more anxiety (-3.8) and depression (-3.0). Patients’ lower HRQoL, increased symptom burden, and increased anxiety and depression were determinants for higher caregiver burden, but not patients’ or caregivers’ sociodemographic characteristics, patients’ neurocognitive functioning, or tumor- and treatment-related characteristics. Conclusions Ten years after initial treatment, up to 35% of informal caregivers reported a clinically relevant burden, which was linked with worse HRQoL, and more anxiety and depression in both patients and caregivers, emphasizing the strong interdependent relationship. Support for meningioma caregivers is therefore warranted.

scholarly journals Decreased Quality of Life in Patients with Acromegaly Despite Long-Term Cure of Growth Hormone Excess

2004 ◽  
Vol 89 (11) ◽  
pp. 5369-5376 ◽  
Author(s):  
Nienke R. Biermasz ◽  
Sjoerd W. van Thiel ◽  
Alberto M. Pereira ◽  
Hendrieke C. Hoftijzer ◽  
Albert M. van Hemert ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nottingham Health Profile ◽  
Depression Scale ◽  
Well Being ◽  
Anxiety And Depression ◽  
Health Profile ◽  
Hospital Anxiety ◽  
Gh Excess

Abstract The long-term impact of acromegaly on subjective well-being after treatment of GH excess is unclear. Therefore, we evaluated quality of life by validated questionnaires in a cross-sectional study of 118 successfully treated acromegalic patients. The initial treatment was transsphenoidal surgery in most patients (92%), if necessary followed by radiotherapy or octreotide. All patients were in remission at the time of assessment (GH, &lt;1.9 μg/liter; normal IGF-I for age). General perceived well-being was reduced compared with controls for all subscales (P &lt; 0.001) as measured by the Nottingham Health Profile and the Short Form-36. Acromegalic patients also had lower scores on fatigue (Multidimensional Fatigue Index) and anxiety and depression (Hospital Anxiety and Depression Scale). Radiotherapy was associated with decreased quality of life in all subscales except for the Hospital Anxiety and Depression Scale, and worsened quality of life significantly, according to the fatigue scores. Somatostatin analog treatment was not associated with improved quality of life. Independent predictors of quality of life were age (physical subscales and Nottingham Health Profile), disease duration (social isolation and personal relations), and radiotherapy (physical and fatigue subscales). In conclusion, patients cured after treatment for acromegaly have a persistently decreased quality of life despite long-term biochemical cure of GH excess. Radiotherapy especially is associated with a reduced quality of life.

scholarly journals Spinal Cord Injuries Among Genders; Psychological Well- Being

2021 ◽  
Vol 8 (3) ◽  
pp. 9-14
Author(s):  
Samir Khan Kabir ◽  
Akhlaq Wazir ◽  
Naseer Hassan ◽  
Ihsan Ullah ◽  
Raza Hassan ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injuries ◽  
Well Being ◽  
Total Sample ◽  
Anxiety And Depression ◽  
Psychological Well Being ◽  
Orthopaedic Department ◽  
Cord Injury ◽  
Male Patients

OBJECTIVES: The aim of this study was to analyse the psychological wellbeing among gender suffering from spinal cord injury (SCI). METHODOLOGY: This was a comparative study. It was conducted from January-March 2020 in Hayatabad Medical Complex (HMC), Peshawar. This study compares the psychological well being in terms of their stress, anxiety, and depression. A questionnaire DASS-42 was used to collect the data from both genders. The inclusion criteria comprise of patients who came for the treatment of their spinal cord injury to the orthopaedic department. Those patients having severe physical and comorbid psychiatric illness were excluded. The data was collected and analysed on SPSS 26. RESULTS: The total sample of 127 in which male were 83 and female were 44. The results were significant according to stress, anxiety, and depression. The level of stress was more in male patients, whereas anxiety results were insignificant among gender and depression were high in females respectively. CONCLUSION: Our results revealed, SCI patients have a high risk of anxiety or depression in among male and female. This information could help physicians understand the long-term risk of new-onset anxiety or depression in SCI patients .  

scholarly journals Long-term physical and psychological outcomes after out-of-hospital cardiac arrest—protocol for a national cross-sectional survey of survivors and their relatives (the DANCAS survey)

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e045668
Author(s):  
Vicky L Joshi ◽  
Lars H Tang ◽  
Britt Borregaard ◽  
Line Zinckernagel ◽  
Tina Broby Mikkelsen ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Depression Scale ◽  
Well Being ◽  
Psychological Problems ◽  
World Health ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Cross Sectional ◽  
Hospital Cardiac Arrest

IntroductionThe number of out-of-hospital cardiac arrest (OHCA) survivors is increasing. However, there remains limited knowledge on the long-term physical and psychological problems suffered by survivors and their relatives. The aims of the DANCAS (DANish cardiac arrest survivorship) survey are to describe the prevalence of physical and psychological problems, identify predictors associated with suffering them and to determine unmet rehabilitation needs in order to make recommendations on the timing and content of future rehabilitation interventions.Methods and analysisThe DANCAS survey has a cross-sectional design involving a survey of OHCA survivors and their relatives. OHCA survivors will be identified through the Danish Cardiac Arrest Registry as having suffered an OHCA between 1 January 2016 and 31 December 2019. Each survivor will be asked to identify their closest relative to complete the relatives’ survey. Contents of survivor survey: EQ-5D-5Level, Hospital Anxiety and Depression Scale, Two Simple Questions, Modified Fatigue Impact Scale, 12-item WHO Disability Assessment Scale 2.0, plus questions on unmet rehabilitation and information needs. Contents of relatives’ survey: World Health Organisation-Five Well-Being Index, Hospital Anxiety and Depression Scale, Informant Questionnaire on Cognitive Decline in the Elderly—Cardiac Arrest and the Modified Caregiver Strain Index. Self-report outcome data collected through the surveys will be enriched by data from Danish national registries including demographic characteristics, circumstances of cardiac arrest and comorbidities. The survey will be completed either electronically or by post December 2020–February 2021.Ethics and disseminationThe study will be conducted in accordance with the Declaration of Helsinki. Surveys and registry-based research studies do not normally require ethical approval in Denmark. This has been confirmed for this study by the Region of Southern Denmark ethics committee (20192000-19). Results of the study will be disseminated via several peer-reviewed publications and will be presented at national and international conferences.

scholarly journals Effect of Psychological well being, Death Anxiety and Depression On curable & Incurable Disease Patients

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Dr. Krishna J. Vaghela
Keyword(s):  
Death Anxiety ◽  
Depression Scale ◽  
Well Being ◽  
Anxiety And Depression ◽  
Psychological Well Being ◽  
Incurable Disease ◽  
Significant Difference ◽  
The Difference ◽  
Anxiety Depression ◽  
Scale Data

The present study has been designed to investigate the difference of psychological well- being, death anxiety, depression between incurable and curable diseases patients. The study was conducted over a sample of eighty patients both incurable diseases patients and curable diseases patients. All participates were administered the psychological well- being scale, death anxiety scale and depression scale. Data was analyzed using t-test. The results reported that exists a statistically significant difference in psychological well-being between incurable and curable diseases patients. As regarding the death anxiety in curable diseases patients was not different significantly from that of patients with incurable diseases. Significant difference is also observed between incurable diseases and curable diseases patients as regarding to their level of depression.

Engagement in activities revealing the body and psychosocial adjustment in adults with a trans-tibial prosthesis

2002 ◽  
Vol 26 (1) ◽  
pp. 15-22 ◽  
Author(s):  
M. K. Donovan-Hall ◽  
L. Yardley ◽  
R. J. Watts
Keyword(s):  
Psychosocial Adjustment ◽  
Depression Scale ◽  
Well Being ◽  
Self Esteem ◽  
The Body ◽  
Anxiety And Depression ◽  
Good Reliability ◽  
Psychological Well Being ◽  
Everyday Activities ◽  
Social Discomfort

The purpose of this study was to examine the effects of the appearance of a prosthesis on social behaviour, social discomfort and psychological well-being in eleven amputees taking delivery of a prosthesis with a silicone cover. Two new scales were developed: the ‘Engagement in everyday activities involving revealing the body’ (EEARB); and the ‘Discomfort-Engagement in everyday activities involving revealing the body’ (Discomfort-EEARB) scales. The psychometric properties of these scales were determined using a sample of 101 able-bodied adults. The Hospital Anxiety and Depression Scale and the Rosenberg Self-Esteem Scale were also used to measure psychological well-being in the amputee sample. The EEARB and Discomfort-EEARB proved to have good reliability and validity. Comparison of amputees’ scores prior to receiving the silicone cosmesis with those of the able-bodied adults revealed significant behavioural limitations and social discomfort, associated with low self-esteem, anxiety and depression. There was a significant increase in amputees’ scores three months afier taking delivery of their prosthesis, indicating that amputees reported engaging in more activities which involved revealing their body, and that they would feel more comfortable in situations which involved revealing the body. As the amputee sample available was small and self-selected, it is not possible to generalise these findings to the amputee population as a whole. However, since there is little previous research investigating the effects of the appearance of the prosthesis, these findings demonstrate the need for further research in this area.

The Colorado Study: Long-Term Solitary Confinement's Impact on Psychological Well-being

2011 ◽  
Author(s):  
Jeffrey L. Metzner ◽  
Jamie Fellner ◽  
Maureen O'Keefe ◽  
Kelli Klebe
Keyword(s):  
Well Being ◽  
Psychological Well Being

Our Bodies, Ourselves Revisited: Male Body Image and Psychological Well-Being

2004 ◽  
Vol 5 (3) ◽  
pp. 228-237 ◽  
Author(s):  
David Tager ◽  
Glenn Good ◽  
Julie Morrison
Keyword(s):  
Body Image ◽  
Well Being ◽  
Male Body ◽  
Psychological Well Being ◽  
Male Body Image

scholarly journals Psychological well-being and illness perceptions in patients with hypopituitarism

Pituitary ◽  
2021 ◽  
Author(s):  
Tessa N. A. Slagboom ◽  
Jan Berend Deijen ◽  
Christa C. Van Bunderen ◽  
Hans A. Knoop ◽  
Madeleine L. Drent
Keyword(s):  
Social Adjustment ◽  
Causal Attributions ◽  
Illness Perceptions ◽  
Causal Attribution ◽  
Depression Scale ◽  
Well Being ◽  
Mood States ◽  
Psychological Well Being ◽  
Language Version ◽  
Sleeping Problems

Abstract Objective The primary aim of the current study was to objectify a spectrum of persisting subjective psychological complaints in patients with hypopituitarism, at least six months after normalizing of the hormonal disturbances. Also, gender differences on these outcomes were investigated. The secondary aim was to identify illness perceptions and causal attributions within this patient group. Methods A total of 42 adult participants (60% females) with treated hypopituitarism once filled out a number of psychological questionnaires. The Profile of Mood States (POMS) and the Hospital Anxiety and Depression Scale (HADS) assessed mood and the Symptom Checklist-90 (SCL-90) and the Work and Social Adjustment Scale (WSAS) assessed well-being. Illness perceptions were identified using the Illness Perceptions Questionnaire-Brief Dutch Language Version (IPQ-B DLV) and causal attributions by using the Causal Attribution List (CAL). Patient outcomes were compared to reference values of healthy norm groups. Results Participants scored significantly worse on the POMS depression, anger, fatigue and tension subscales, the SCL-90 psychoneuroticism, depression, inadequacy of thinking and acting and sleeping problems subscales and all subscales of the WSAS when compared to reference data. Women also scored worse on depression (HADS) and somatic symptoms (SCL-90). Compared to other illnesses, patients with hypopituitarism have more negative and realistic illness perceptions on consequences, timeline, identity and emotions. Participants attributed their complaints more to physical causes than psychological causes. Conclusion Despite normalization of hormonal disturbances, patients with hypopituitarism in general can still experience problems during daily living, such as negative mood states and a decreased psychological well-being.

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