The relationships between cancer diagnosis/prognosis awareness and quality of life, anxiety, and depression in Chinese gastroesophageal cancer patients: A cross-correlation analysis.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e24111-e24111
Author(s):  
Long Wang ◽  
Jing Zuo ◽  
Yudong Wang ◽  
Li Feng ◽  
Xue Zhang ◽  
...  

e24111 Background: Many gastroesophageal cancer patients in China are not made aware of their cancer diagnosis/prognosis. Explorations of the differences in depression, anxiety and quality of life between cancer patients with and without such awareness are rare. The aim of this study was to evaluate the correlation between cancer awareness status and quality of life, anxiety and depression in gastroesophageal cancer patients. Methods: Participants were gastroesophageal cancer patients recruited from a medical center in North China. The degree of awareness of their cancer diagnosis/prognosis was evaluated via interviews. Data were collected using the Self-Rating Anxiety/Depression Scale and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and were analyzed using quantitative methods. Results: The study included 157 gastroesophageal cancer patients: 31 were completely unaware of their cancer diagnosis/prognosis (19.75%); 51 were partly aware (32.48%); and 75 were fully aware (47.78%). Thirty patients (19.11%) experienced anxiety and 35 (22.9%) depression. Unawareness of the real disease status was significantly correlated with worse quality of life (cognitive functioning, social functioning and appetite loss) ( Ps < 0.05) and anxiety ( P = 0.003). Conclusions: More than 50% of gastroesophageal cancer patients were unaware their diagnosis/prognosis completely and were more likely to experience worse quality of life and anxiety. Medical staff and family members should take appropriate measures to make patients aware of their cancer diagnosis/prognosis, as awareness is valuable for improving quality of life and negative emotions, contributing to the successful overall management of gastroesophageal cancer.

2020 ◽  
Vol 28 (11) ◽  
pp. 5469-5478
Author(s):  
Yemataw Wondie ◽  
Andreas Hinz

Abstract Purpose Cancer is of increasing prevalence in less-developed countries. However, research on the patients’ quality of life (QoL) in these countries is very limited. The aim of this study was to examine QoL of cancer patients in Africa. Method A sample of 256 cancer patients treated in an Ethiopian hospital was examined with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire EORTC QLQ-C30, the Multidimensional Fatigue Inventory, and the Hospital Anxiety and Depression Scale. A group of 1664 German cancer patients served as a comparison group. Results Most of the scales of the EORTC QLQ-C30 showed acceptable reliability in the Ethiopian sample. Compared with the German cancer patients, the Ethiopian patients showed lower QoL in most dimensions, especially in financial difficulties, physical functioning, pain, and appetite loss (effect sizes between 0.52 and 0.75). Illiteracy, tumor stage, and treatment (surgery and chemotherapy) were associated with QoL in the Ethiopian sample. QoL was strongly correlated with fatigue, anxiety, and depression. Conclusion The EORTC QLQ-C30 is a suitable instrument for measuring QoL in Ethiopia. The detriments in QoL in the Ethiopian patients indicate specific cancer care needs for the patients in a developing country.


2004 ◽  
Vol 2 (2) ◽  
pp. 115-124 ◽  
Author(s):  
JÖRG DIRMAIER ◽  
SILKE ZAUN ◽  
UWE KOCH ◽  
TIMO HARFST ◽  
HOLGER SCHULZ

Objective: Recent years have shown an increase in the use of questionnaires measuring health-related quality of life to verify the quality of treatment in the field of oncology. An often used cancer-specific questionnaire is the “Quality of Life Core Questionnaire of the European Organization for the Research and Treatment of Cancer” (EORTC QLQ-C30). The purpose of this study is to analyze the psychometric properties of the EORTC QLQ-C30 (version 1) in order to determine the feasibility and appropriateness for its use in inpatient cancer rehabilitation in Germany with heterogeneous diagnoses.Methods: The questionnaire was administrated to a sample of 972 cancer patients at the beginning of treatment and to 892 patients after treatment. Besides descriptive analysis, the statistical analyses include confirmatory analysis and the multitrait/multimethod approach to test the questionnaire's postulated scale structure (factorial validity) and its reliability (internal consistencies). The analysis also includes a comparison of responsiveness indices (effect size, reliable change index) to test the sensitivity of the instrument.Results: The EORTC QLQ-C30 showed satisfactory levels of reliability and sensitivity, but the postulated scale structure could not be confirmed. The results illustrate that the varimax-rotated solution of a principal component analysis does not confirm the scale structure postulated by the authors. Correspondingly, the selected fit indices within the scope of the confirmatory factor analysis do not show satisfactory results either.Significance of results: We therefore consider version 1 of the EORTC QLQ-C30 to be only limitedly useful for the routine assessment of changes in the quality of life of cancer patients in inpatient rehabilitation in Germany, especially because of the instrument's length and possible redundancies. For this reason, a scoring procedure limited to a subset of items is suggested, revealing satisfactory to good psychometric indices. However, further psychometric tests are necessary, especially with regard to validity and sensitivity.


1995 ◽  
Vol 13 (5) ◽  
pp. 1249-1254 ◽  
Author(s):  
M J Hjermstad ◽  
S D Fossa ◽  
K Bjordal ◽  
S Kaasa

PURPOSE The European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) is a well-validated instrument that assesses health-related quality of life (HRQOL) in cancer patients. It is used in cancer clinical trials in Europe, Canada, and the United States, and has demonstrated high reliability and validity in different groups of cancer patients. Despite thorough testing of reliability and validity, we have not identified any reports on its test/retest reliability; thus, a test/retest study was performed at the Norwegian Radium Hospital (NRH). MATERIALS AND METHODS Cancer patients from the outpatient clinic who were off treatment for > or = 3 months were eligible for the study. The EORTC QLQ-C30 was given to the patients when they presented for their visit. The second questionnaire was received by the patients 4 days later. Of 291 eligible patients, 270 (93%) agreed to participate and 190 (73%) completed both questionnaires. RESULTS The test/retest reliability measured by Pearson's correlation coefficient was high for all functional scales, with a range from .82 for cognitive and role function to .91 for physical function. The r value for global HRQOL was .85. For the symptom scales--nausea/vomiting, fatigue, and pain--the coefficients were .63, .83, and .86, respectively. The single-item coefficients ranged from .72 for diarrhea to .84 for financial impact. The Spearman rank correlation was in the same range for all dimensions. CONCLUSION The EORTC QLQ-C30 seems to yield high test/retest reliability in patients with various cancer diagnoses whose condition is not expected to change during the time of measurement.


2017 ◽  
Vol 17 (2) ◽  
pp. 458-466 ◽  
Author(s):  
Byeongsang Oh ◽  
Thomas Eade ◽  
Andrew Kneebone ◽  
George Hruby ◽  
Gillian Lamoury ◽  
...  

Background. Guidelines surrounding optimum needle retention duration in acupuncture have not been established, despite a growing evidence base for acupuncture over recent decades. This retrospective study explored the effect of varying acupuncture needle retention durations in cancer patients. Method. Patients received either 2 (n = 35), 10 (n = 53), or 20 minutes (n = 54) of acupuncture once a week for 6 weeks. Outcomes of anxiety and depression, stress, fatigue, and quality of life (QOL), with the Hospital Anxiety and Depression Scale, Perceived Stress Scale, Functional Assessment of Cancer Therapy–Fatigue, and European Organization for Research and Treatment of Cancer Quality of Life, were measured at baseline and at 6 weeks following the intervention. Results. The mean age of participants was 58 years (n = 152). The majority were female, diagnosed with breast cancer. Depression, stress, fatigue, and QOL were significantly improved in all 3 groups at 6 weeks postintervention. No significant differences in all outcomes were found between the 3 groups (≤2 vs 10 minutes vs 20 minutes). There were no differences with the satisfaction of the acupuncture services and perceived efficacy of acupuncture among the 3 groups. More than 95% of participants indicated that they would recommend acupuncture to other cancer patients, friends, and their family members. Conclusion. The efficacy of acupuncture may not only depend on needle retention duration, but may also be associated with multiple factors. Considering the limitations of this study design, robust randomized controlled studies are warranted to confirm the findings.


Author(s):  
Ranjini Nanjaiah ◽  
Mudassir A. Khan ◽  
Vadiraja N. Rao

Background: The survival rate of cancer patients has improved and focus has shifted to improve the quality of life of the survivors. An adequate knowledge is required for psychosocial interventions and designing programs aimed at improving the quality of life of the cancer patients. The purpose of the study is to assess Anxiety and Depression [Psychiatric morbidity] among gynaecological cancer subjects and its association with duration since diagnosis, type of cancer, mode of treatment and socio-demographic variables.Methods: This is an interview based cross sectional study involving 131 patients diagnosed to have gynaecological cancer who were evaluated using hospital anxiety and depression scale (HADS). The gynaecological and socio-demographic data was analyzed for any correlation with HADS scores.Results: The prevalence of at least one psychiatric disorder was 90% (n=118). Sixty subjects [45.8%] had anxiety, 71 subjects [54%] had depression and 118 cases [90%] had psychiatric morbidity.  Patients suffering for less than three months had anxiety; three to 12 months were both anxious and depressed; more than 12 months were depressed. Young women with less education were more anxious compared to educated women.Conclusions: Given a gynaecological cancer an individual will have 0.9 chance of developing psychiatric morbidity. Young women with less education aware of cancer diagnosis for three to 12 months were at increased risk and needs intervention. As cancer incidence is increasing and psychiatric morbidity is common among cancer patients, training of health care personnel in cancer screening and recognizing patients with common mental disorders is required to improve their quality of life. Creating awareness of public regarding risk factors of cancers, importance of screening and cancer treatment is necessary.


BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e056187
Author(s):  
Bang Wool Eom ◽  
Dong-Hoe Koo ◽  
Ji Yeong An ◽  
Han Hong Lee ◽  
Hyoung-Il Kim ◽  
...  

IntroductionPatients who underwent curative gastrectomy for gastric cancer are regularly followed-up for the early detection of recurrence and postoperative symptom management. However, there is a lack of evidence with regard to proper surveillance intervals and diagnostic tools. This study aims to evaluate whether frequent surveillance tests have a survival benefit or improve the quality of life in patients who underwent curative resection for advanced gastric cancer.Methods and analysisThe STOFOLUP trial is an investigator-initiated, parallel-assigned, multicentre randomised controlled trial involving 16 hospitals in the Republic of Korea. Patients (n=886) diagnosed with pathological stage II or III gastric adenocarcinoma will be randomised to either the 3-month or the 6-month group at a 1:1 ratio, stratified by trial site and tumour stage. Patients allocated to the 3-month group will undergo an abdominal CT scan every 3 months postoperatively and those allocated to the 6-month group will undergo CT every 6 months. The primary endpoint is 3-year overall survival and the secondary endpoints are quality of life, as assessed using KOrean QUality of life in Stomach cancer patients Study group-40, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and the stomach cancer-specific module (STO22), and nutritional outcomes. Other survival data including data concerning 3-year disease-free survival, recurrence-free survival, gastric cancer-specific survival and postrecurrence survival will also be estimated. The first patient was enrolled on July 2021 and active patient enrolment is currently underway.Ethics and disseminationThis study has been approved by the Institutional Review Board of eight of the participating hospitals (NCC 2021-0085, KBSMC2021-01-059, SMC 2021-01-140, KC21OEDE0082, 4-2021-0281, AJIRB-MED-INT-20-608, 2021-0515 and H-2102-093-1198). This study will be disseminated through peer-reviewed publications, national or international conferences.Trial registration numberNCT04740346.


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