Application of Next-Generation Plant-Derived Nanobiofabricated Drugs for the Management of Tuberculosis

2021 ◽  
pp. 81-100
Author(s):  
Charles Oluwaseun Adetunji ◽  
Olugbenga Samuel Michael ◽  
Muhammad Akram ◽  
Kadiri Oseni ◽  
Ajayi Kolawole Temidayo ◽  
...  
Keyword(s):  
Next Generation ◽  
Generation Plant

Next Generation CANDU Performance Assurance

2002 ◽  
Author(s):  
David J. Wren ◽  
P. J. Allsop ◽  
J. M. Hopwood
Keyword(s):  
Product Development ◽  
Large Scale ◽  
Low Cost ◽  
Development Program ◽  
Next Generation ◽  
Customer Expectations ◽  
Generation Plant ◽  
Reliable Performance ◽  
And Performance ◽  
Under Construction

AECL is developing a next generation CANDU design to meet market requirements for low cost, reliable energy supplies. The primary product development objective is to achieve a capital cost substantially lower than the current nuclear plant costs, such that the next generation plant will be competitive with alternative options for large-scale base-load electricity supply. However, other customer requirements, including safety, low-operating costs and reliable performance, are being addressed as equally important design requirements. The main focus of this paper is to address the development directions that will provide performance assurance. The next generation CANDU is an evolutionary extension of the proven CANDU 6 design. There are eight CANDU 6 units in operation in four countries around the world and further three units are under construction. These units provide a sound basis for projecting highly reliable performance for the next generation CANDU. In addition, the next generation CANDU program includes development and qualification activities that will address the new features and design extensions in the advanced plant. To limit product development risk and to enhance performance assurance, the next generation CANDU design features and performance parameters have been carefully reviewed during the concept development phase and have been deliberately selected so as to be well founded on the existing CANDU knowledge base. Planned research and development activities are required only to provide confirmation of the projected performance within a modest extension of the established database. Necessary qualification tests will be carried out within the timeframe of the development program, to establish a proven design prior to the start of a construction project. This development support work coupled with ongoing AECL programs to support and enhance the performance and reliability of the existing CANDU plants will provide sound assurance that the next generation CANDU plants will meet customer expectations.

scholarly journals Virtual Plant Tissue: Building Blocks for Next-Generation Plant Growth Simulation

2017 ◽  
Vol 8 ◽  
Author(s):  
Dirk De Vos ◽  
Abdiravuf Dzhurakhalov ◽  
Sean Stijven ◽  
Przemyslaw Klosiewicz ◽  
Gerrit T. S. Beemster ◽  
...  
Keyword(s):  
Plant Growth ◽  
Plant Tissue ◽  
Building Blocks ◽  
Next Generation ◽  
Growth Simulation ◽  
Virtual Plant ◽  
Generation Plant

scholarly journals Precision genetic engineering tools for next-generation plant breeding

2019 ◽  
Vol 38 (4) ◽  
pp. 435-436 ◽  
Author(s):  
Günther Hahne ◽  
Laurence Tomlinson ◽  
Fabien Nogué
Keyword(s):  
Genetic Engineering ◽  
Plant Breeding ◽  
Next Generation ◽  
Generation Plant

Targeted enrichment strategies for next-generation plant biology

2012 ◽  
Vol 99 (2) ◽  
pp. 291-311 ◽  
Author(s):  
Richard Cronn ◽  
Brian J. Knaus ◽  
Aaron Liston ◽  
Peter J. Maughan ◽  
Matthew Parks ◽  
...  
Keyword(s):  
Plant Biology ◽  
Next Generation ◽  
Generation Plant ◽  
Targeted Enrichment

scholarly journals The next generation leased line telecommunication protection for high voltage substation

2021 ◽  
Author(s):  
Murad Hussain
Keyword(s):  
Control System ◽  
High Voltage ◽  
Next Generation ◽  
Protection Scheme ◽  
Generation Plant ◽  
Generation Company ◽  
Zone Of Influence ◽  
Minor Flaw ◽  
A Minor

Telecommunication circuits and leased lines have been in use for controlling substations for many years. These circuits have usually been engineered according to set standards however recent studies have shown that the parameters used for engineering the telecommunication circuits have various design flaws that may put these circuits. in jeopardy during a local substation fault. The existing protection scheme for SolarI wind and other relevant power generating farms are such that if they lose communication with the local Utility Transmission Station (UTS)I the UTS automatically trips a local breaker and knocks the generation plant off the grid this could mean thousands of dollars in lost revenue for the generation company hence even a minor flaw in the telecommunication circuits can have a significant impact on the substation control system. This case study reviews the challenges of designing these telecommunication circuits for control and monitoring of substations and also reviews the case study performed by Hydro Quebec on the concept of Zone of Influence. In addition this study also proposes an alternate telecommunication model that when implemented will be able to withstand all the challenges of designing a circuits for the high voltage substation.

scholarly journals Discovering the Next-Generation Plant Protection Products: A Proof-of-Concept via the Isolation and Bioactivity Assessment of the Olive Tree Endophyte Bacillus sp. PTA13 Lipopeptides

Metabolites ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 833
Author(s):  
Evgenia-Anna Papadopoulou ◽  
Apostolis Angelis ◽  
Lemonia Antoniadi ◽  
Konstantinos A. Aliferis ◽  
Alexios-Leandros Skaltsounis
Keyword(s):  
Plant Protection ◽  
Bioactive Compound ◽  
Olive Tree ◽  
Plant Protection Products ◽  
Colletotrichum Acutatum ◽  
Bacillus Sp ◽  
Proof Of Concept ◽  
Next Generation ◽  
Selective Toxicity ◽  
Generation Plant

Endophytic microorganisms (EMs) have recently attracted interest for applications in plant protection, mainly due to their bioactive compound-producing capacity. Therefore, we underwent the task of isolating olive tree EMs and investigating their bioactivity against the devastating pathogen Colletotrichum acutatum. Several EMs were isolated; however, the Bacillus sp. PTA13 isolate exhibited the highest toxicity to the phytopathogen. Bacteria of the genus Bacillus exhibit superior bioactive metabolite-producing capacity, with the lipopeptides (LPs) of surfactin, iturin, and fengycin groups being the most studied. A total LP extract and several fractions were obtained, and their bioactivity was assessed against C. acutatum strains. LPs of the major surfactin, iturin, and fengycin groups and the minor gageotetrin and bacilotetrin groups were annotated. The results confirmed the bioactivity of the major LPs, with fengycins being the most fungitoxic. Interestingly, the minor LP fraction exhibited selective toxicity to the fungicide-resistant C. acutatum isolate, an observation that highlights the significance of our approach to comprehensively mine the total LP extract. This work represents a proof of concept of the exploitation of EMs in customized olive tree plant protection and aligns well with strategies that focus on the sustainability and safety of food production via the development of next-generation plant protection products.

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